Dqui013211.1
Basic Information
- Insect
- Drosophila quinaria
- Gene Symbol
- spopl
- Assembly
- GCA_035047525.1
- Location
- JAWNPO010000455.1:17935000-17944685[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 1.4 3.8e+02 1.6 0.0 8 30 140 162 133 165 0.86 2 3 2.1e-17 5.7e-15 55.8 0.0 12 107 868 961 860 964 0.91 3 3 4.6 1.2e+03 0.0 0.0 79 109 965 995 961 996 0.89
Sequence Information
- Coding Sequence
- ATGGCGTTGGAGCACACATTCCTTGGGACCTGGGAGATAGTTTCCTGCACTTTTGAGGGAAAGCGTGAATTATCCGGACTGGAGGGCATAAAATTTCGACTGGATGACACTAGTGACATTACCTGGTACAATGATCTAATTAGCCCACTTCCAGAAAGAAAAGACTGTGGTACTGTCTGTGATTCAGCAAATGTCTTATTTAGCTGTGAGACATTTGATGTGCACGAAGCTAATCCCCGTCTGATCTTTGGTGCTTTTGCTGGACACAGCATAGAGTTCAGTACAAACACTCTTATGCCAAGTGATACTTTGGTTCTTAGCTGTGAGAATTGGTATTCAGTCAAGTGCAAAAGGCTTAAAGATGATCAGGCAGCGGGCCAGGAGAGACAATTTAGCTTTGGTGAGGCTCTAGTGGAGACTTATTTTAGCGATGTTATGGTGAAAAGTGGCAGTGGCATGGAATTCGCTGTGCATGCATCTATTCTACGTCTTAACGGATTTGACTGCAGCATGTGCACCAGCAGTGTGGCGATTCCAACGCCATCGCGAAGTCAAAGCCCTTTGTACAATGAATCTCACATAGCCAACCATAGTCCCATAAGCATATTGGTAGCAGGCGATAGTGGCGATGTGAAACAGCAGCTATTATCAAGCTTAAACCTGTCCCCGACTTATTTACAACCACCATGCAATTTCCAGCTAATGGATGCCGATTCCGATAGTCTAGGAACGTTGCGTTTACACCCGTTTAGTAGCAGCTTTAACTGTCTAAGCAATGGTAATGCAGAGGACTTTTTGCGAATATCTATTGATAGCGGTAATGAATTGCTTAGCTTGGAGAGCGGTGGTATACGACGATTTCCACCCACATCACACTCGGATTCGCATCTAGAGGCTTCGCAGGTacattgcaaaaatatttttaatttttgccagGATATGATACTCCAGCCGATGCCATCGTCCAATCCGCCAACAAGTAGTCCAGCTTGTGGCTTAACTGTATGCAGTACACGGCGACCGCCACTTTCACCGTATCGAGCACGTAGTCCTTCACCATTTCCAAGCTCAATGGATACGCCACCATCGTCACCACTTACGCCAGTCGGCGTTCTTTATAACCTGCCTACTTTACTACTTAGCCCAATTTTGCACTGGCTTTACACGGAGTCCATGCTACCCGAGCTGGATGAAAATATCTGTGAGAAACTAATCATCTTAGCTGAAGCACAGCCCCCGCTAACAAAGCTGGTGGAGCCAACACGCAAATACCTGAGACTGCTACGacttaaaaaatTTGTAGTCAATGTGACCATGGATCTGCACAGCATTCTCAATCGTGTTATTCAGCGCATAGATCCTGATTGCCTATCGCACGAGCCCGCCTTGCTCTATGCAACCTTTCAGGATGTTCTTCGAGATTGTGCTATTGGATGTGCAAAGGTTCTgcaattttgcaatatatttataaaggaTGCCACGCACCTTGAGCGttatcaaaaaaatgaaattgtcaAATACGTGCGCACTCGCATTCCGATATTCATGACGCAAGCACATCAACTGTTGCAAAATGTGCTAGGAGTTCTTGTAGATCTAAGCATTGATGAAAAGGCAGAGTTGGTGAATTATCTTGTACCTGAGATTGAGTCGAccttattaattttatcagCTGTGATAGAGGAAATTAAAACCTCACTGGAAACTATGTGTAAGGATTTGAAGTGCACACACTTGGATCAAGCTCTCCATCAACAAACGGACGATGCTCTTGGTATGCAGCTGCAGTACGTGAGCGGAGAAGTGCTAACACCTCGTCCTCGTCGGGGACCACCTATCGGCTTAATGCTGTACGAAAATCCTACAGAACAGCGAAAAAGTTGCGGCGAGAACGATCTCAAGTTTGTGCTTTATATGTGCAAAGTGCGTAAAATGCGTGATATTTATGGTCGCATATCTGCAGCACTTGACATTATCAAAGCGAAGAGAAGCACCTTCTGTGAAATGGATTTCCCTAGTAAACAGAGTACTATCAATCAAAATCTTGAGCAGCTAATAATGGATATACCAGCATATATAAAACTGATACAAAATTTATCAGATCGCCTGGACGACAAATTGGGCTGGAAAgagtttaaattttgtttcaagTTGGCTACAAGTCAAATTaacgGTGTTATTGTCAAGCTGTTGGATCAGAAGTCAGCCCTGCGTCACGCTATTGAACAAATTTGTAAACTAGTAAAAGAGCAAGAGTTTTTGAAAGCTATTGTAGAACTTGGCCTCTTAGAGTCATCAAATCTGCTACAACAAGATTTAAAGATAGCTGACCATGAGAACAATTTGGATATGGACACAAACGAGGCGGAAACTATGCATAAATACAACTATGATTACAAGAATATCAagCTCAATTTAATTAGGCATTTGTGCGAGCCGCCCATTGCCGCCAATAGCAATCTATCGAAAAATGCTTTGCGTTTACTTCACTCCGCACAACTGGCTGACATGGAGTTTGAGGTTCAAACATATACAACATCTGCAACAGCTAAAAAAGATGAGGCCGCAGCTGAGTTGACGTCGAAGAGTTCTGGGCCAACAAATGTGGCACTGCAAGTGCATAGCTTTAAGGCACATCGTGTAATTGTGGCAGCTCGTTGCGAATGGTTTAAGAAAGCTCTTATGTCTGGCATGCAGGAGTCAATTAACAAAAAGGTCATAATCACAGATACTTCGCCGGTAATATTTCGAAGGTTGCTTCTATATCTGTATGGCGCTCCCATTGACCGCACCGTTGGAGCCGAGCAAATTTGCGAACTAATGTTGCTAGCTGATAGATACTCCGTGGATGATCTAAAGGAGCTGTGTGAAAATACATTGAACTCATTGATCGATGAGGAATCGGTTGTCTGTCTACTGGGCATTGCTGACCGTTACATGGCCACGGTGCTAAAATCCAACTGTCTATCGTTTCTATCACAACATGCTGAATTAACTAAAAGTGAGATATTTAAGGAACTACCACAGAACTTACAGTTAGAGGTCATGGATTTGGTACAATGGTTTGGTCGCGTTTCGGAGCCATGGAATGATCACAGCTTTCAATCAGACAGCAAGGCACGACACTGCCTAAAAAGCCCGTCTAAACCTCGCTTACGATCCCGTAAATCATCTCCTTCCTATATATGA
- Protein Sequence
- MALEHTFLGTWEIVSCTFEGKRELSGLEGIKFRLDDTSDITWYNDLISPLPERKDCGTVCDSANVLFSCETFDVHEANPRLIFGAFAGHSIEFSTNTLMPSDTLVLSCENWYSVKCKRLKDDQAAGQERQFSFGEALVETYFSDVMVKSGSGMEFAVHASILRLNGFDCSMCTSSVAIPTPSRSQSPLYNESHIANHSPISILVAGDSGDVKQQLLSSLNLSPTYLQPPCNFQLMDADSDSLGTLRLHPFSSSFNCLSNGNAEDFLRISIDSGNELLSLESGGIRRFPPTSHSDSHLEASQVHCKNIFNFCQDMILQPMPSSNPPTSSPACGLTVCSTRRPPLSPYRARSPSPFPSSMDTPPSSPLTPVGVLYNLPTLLLSPILHWLYTESMLPELDENICEKLIILAEAQPPLTKLVEPTRKYLRLLRLKKFVVNVTMDLHSILNRVIQRIDPDCLSHEPALLYATFQDVLRDCAIGCAKVLQFCNIFIKDATHLERYQKNEIVKYVRTRIPIFMTQAHQLLQNVLGVLVDLSIDEKAELVNYLVPEIESTLLILSAVIEEIKTSLETMCKDLKCTHLDQALHQQTDDALGMQLQYVSGEVLTPRPRRGPPIGLMLYENPTEQRKSCGENDLKFVLYMCKVRKMRDIYGRISAALDIIKAKRSTFCEMDFPSKQSTINQNLEQLIMDIPAYIKLIQNLSDRLDDKLGWKEFKFCFKLATSQINGVIVKLLDQKSALRHAIEQICKLVKEQEFLKAIVELGLLESSNLLQQDLKIADHENNLDMDTNEAETMHKYNYDYKNIKLNLIRHLCEPPIAANSNLSKNALRLLHSAQLADMEFEVQTYTTSATAKKDEAAAELTSKSSGPTNVALQVHSFKAHRVIVAARCEWFKKALMSGMQESINKKVIITDTSPVIFRRLLLYLYGAPIDRTVGAEQICELMLLADRYSVDDLKELCENTLNSLIDEESVVCLLGIADRYMATVLKSNCLSFLSQHAELTKSEIFKELPQNLQLEVMDLVQWFGRVSEPWNDHSFQSDSKARHCLKSPSKPRLRSRKSSPSYI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00584520;
- 90% Identity
- iTF_00601917;
- 80% Identity
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