Dput012167.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila putrida
Gene Symbol
ken
Assembly
GCA_037043535.1
Location
JBAMBI010000472.1:3587725-3589473[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7e-22 1.3e-19 70.4 0.1 7 104 23 119 18 125 0.91

Sequence Information

Coding Sequence
atgttgatgttgcaatATAGCAAACATGGCGAGTGTATACTCAAAGAAATCGGAGCAGCGTTTAGAGGGGAGCATCCAGCGGACTTAACAATCGTGTGTGAGAATAAGGTGAAGCTTCATGCCCACAAACTGGTACTCGCCGCTGCCAGTCCACTTATAAGGAATTTGTTGGAGGACACGCATTTAAGTGATTGTACTACAACCGTATATTTTCCGGACGTCAATGCCACCTATTTTAAATTCCTACTGGATTTCTTATATTCCGGTCAGACATGTATCACATCCAGGGACGTGAACTATCTGCACGatctgttgctattgctgcagATCAAGTCGGACAGCTGGAAGACAACAGATTCCGCATATCTGAGTAGTAAATGCTCCAGCTTACGGGAAAGGCCTAGAAAACAGTACTCTTCCTCCCAGAACTTAGATCAATCGTTGAAATATGAGGTGGAAAGTGTCGATGATAATAGAAATATTGGAGATTTCTCCACATTTTCCGCCGAGAATTGTGAGAGTGCGATCGATGATTGCCCGCAAaaagaagatgatgatgattccGCCAATAATAAGGACAACAAAAGCGACAAAGACACTGATGAAATTGTAAATCTTTCCAACATTCCAGCTAGTGGACTTGCCAATAGCAtcaccaataacaacaacaacagcaacaacaataataattcgACAATAAACCCAGTTAATCTATCGCTTGACCTTcgaacaaaaaatgaaaatgcagctCGCAGTGAAATGAGTAAAAGTTTTCTGCAAAAACACAATAATAGCGATACAATCAGCGCCAATGAGAGCACGAAGCGAAAAGGACTCTTTTTTGAGTCGCACAAGGATGTGATGAAGCCCCTCTCCGATGGATCTGATATCAATAGTTCGCCCGAGAATTATGTTGTAACGCCGCATCGAAAACGACGACCTGGTTTTCACAATACACAGAGCGATAATCAACCGTTTACGACATATCAACATAATCTATTGGAGGAACTGCGACTGGTAAAGTCGACATCATCGCCAATATCGGGATTGGGTTCGGAAAAGAATATGTTATCCCATCTGGAGGATGGTGCACTTAATGCGGAATCAATGACCCCGGAACGGAAACTTCTTGAATCACAACGGAATCGAGGACAAAGTCCCGAACTACAAATGCATCTTGGCCAACAGTTTGTCTATCAATGGCAGTCGAATCAAAGTGCTGCCATTTCGTCAATGCCCAACTTGCAATCGCGACTATCGAGTCTATCgcatattaacttaaatttggACCCAGATAGTCGCAATAGCAGCACTTCCGTATCCAATATTTCAACTAACAATACGCACTCATCGTCGGTCCGTGAATATCGTTGCGAATACTGTGGCAAACAGTTTGGCATGTCATGGAACCTTAAGACCCATCTCCGCGTACACACGGGCGAAAAGCCGTTTGCCTGTCGCCTCTGTGTGGCAATGTTTAAGCAGAAGGCGCATCTTTTGAAGCATCTGTGCTCGGTTCACCGAAATGTTATAACCACAACAAATGGCACGGATACGGAGAATCGATAtagctgctgcttctgttccATGTGCTTTGAATCGGTGCAGGAACTTGTCCGCCATCTGTCCGGACACCATAATAACCTTCTGCTCACTAAGAATCTTCGGGAATAA
Protein Sequence
MLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCTTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCSSLRERPRKQYSSSQNLDQSLKYEVESVDDNRNIGDFSTFSAENCESAIDDCPQKEDDDDSANNKDNKSDKDTDEIVNLSNIPASGLANSITNNNNNSNNNNNSTINPVNLSLDLRTKNENAARSEMSKSFLQKHNNSDTISANESTKRKGLFFESHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTTYQHNLLEELRLVKSTSSPISGLGSEKNMLSHLEDGALNAESMTPERKLLESQRNRGQSPELQMHLGQQFVYQWQSNQSAAISSMPNLQSRLSSLSHINLNLDPDSRNSSTSVSNISTNNTHSSSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGTDTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00608814; iTF_00558289; iTF_00608540; iTF_00558014; iTF_00584063; iTF_00471239; iTF_00569068; iTF_00470965; iTF_00569339; iTF_00529193; iTF_00528904; iTF_00337131; iTF_00336871; iTF_00337673; iTF_00338500; iTF_00339269; iTF_00338762; iTF_00337944; iTF_00339513; iTF_00575979; iTF_00575687; iTF_00579371; iTF_00579618; iTF_00537868; iTF_00537605; iTF_00586060; iTF_00586313; iTF_00589164; iTF_00588931; iTF_00832268; iTF_00832522; iTF_00806063; iTF_00806316; iTF_01554799; iTF_01555052; iTF_00523312; iTF_00523049; iTF_00805585; iTF_00805285; iTF_01553329; iTF_01553582; iTF_00587763; iTF_00587495; iTF_00533908; iTF_00534214; iTF_00520725; iTF_00472450; iTF_00553799; iTF_00554034; iTF_00556850; iTF_00472695; iTF_00556601; iTF_00614283; iTF_00562800; iTF_00562561; iTF_00509439; iTF_00509193; iTF_00336054; iTF_00336340; iTF_00493046; iTF_00493269; iTF_00589878; iTF_00589635; iTF_00479129; iTF_00478821; iTF_00595577; iTF_00595338; iTF_00510906; iTF_00510641; iTF_00541850; iTF_00542062; iTF_00506972; iTF_00803228; iTF_00802945; iTF_01320092; iTF_01319857; iTF_00585309; iTF_00585594; iTF_01559133; iTF_01559373; iTF_01570333; iTF_01570573; iTF_00803998; iTF_00803696; iTF_01356222; iTF_01356477; iTF_00519551; iTF_00519259; iTF_00901855; iTF_00901596;
90% Identity
iTF_00608814; iTF_00558289; iTF_00608540; iTF_00558014; iTF_00584063; iTF_00579371; iTF_00579618; iTF_00537868; iTF_00537605; iTF_00586060; iTF_00586313; iTF_00587763; iTF_00587495; iTF_00533908; iTF_00534214; iTF_00585309; iTF_00585594; iTF_00519551; iTF_00519259;
80% Identity
iTF_00584063;