Basic Information

Insect: Drosophila pullipes
Gene Symbol: ush
Assembly: GCA_035043795.1
Location: JAWNMT010000181.1:38652-57144[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.05 3.2 8.3 0.0 1 20 204 223 204 225 0.89

2 9 0.00029 0.018 15.3 0.8 1 23 280 302 280 302 0.98

3 9 0.052 3.3 8.2 1.0 2 21 354 373 354 374 0.92

4 9 0.036 2.3 8.7 3.0 2 21 763 782 762 783 0.93

5 9 0.0093 0.59 10.6 0.0 3 21 833 851 831 852 0.91

6 9 0.019 1.2 9.6 0.0 2 23 922 943 921 943 0.98

7 9 0.0039 0.25 11.8 1.3 1 23 949 971 949 971 0.99

8 9 0.0013 0.079 13.3 1.8 1 23 1036 1059 1036 1059 0.96

9 9 0.31 20 5.8 0.7 2 20 1169 1187 1168 1189 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.05	3.2	8.3	0.0	1	20	204	223	204	225	0.89
2	9	0.00029	0.018	15.3	0.8	1	23	280	302	280	302	0.98
3	9	0.052	3.3	8.2	1.0	2	21	354	373	354	374	0.92
4	9	0.036	2.3	8.7	3.0	2	21	763	782	762	783	0.93
5	9	0.0093	0.59	10.6	0.0	3	21	833	851	831	852	0.91
6	9	0.019	1.2	9.6	0.0	2	23	922	943	921	943	0.98
7	9	0.0039	0.25	11.8	1.3	1	23	949	971	949	971	0.99
8	9	0.0013	0.079	13.3	1.8	1	23	1036	1059	1036	1059	0.96
9	9	0.31	20	5.8	0.7	2	20	1169	1187	1168	1189	0.91

Sequence Information

Coding Sequence: ATGATCAGCAgtcaaacaacagcagcaacaataaaagGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGAATTGGCCGCACACGAGCTGAGCGaggagaagcaacagcaacaccagcagcaccaacaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCTTGCAACCCATCGAGACTGACATGGAACAGGAACTGGAGGAGGCGCAAGCGGCAGCCCAGGATTCCAGCGACCAGAAGTTGGCGGACAACCCGACCACGACGACGCCGCCGCGCAGCCCAACGCCTGGAGAACTGGTGCCAAAGCTGGAGAGAGCTGATACGCCTCCCTCAGTTCCAGTCACGCCCAGTCCACCACCGCGCACGCCCACACCACCGCCAATTGTACTGCCCAAGCTGCGACTCAATGCGTTGCTTGCCTCAGATCCGGCATTGAAGCCCGATGCCAAGGAGCTCAATTTGCACGAGTCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAGCCGACTCTGCAGCCAGATGTGGAGCCGCTATTGAAACCGGCGCGATTTATGTGCCTGCCGTGCAGCATCGCTTTCAGTTCACCATCAACGCTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGCAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCcaatgccaacagcagctccagcgGCTCAACTGCCGCCGGCTCCGAGCCGCCCAACAAGATGTCCCGCATTGGCAAGCAATATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGACACATGCGCATGCATCAAACATCCCCAGCGACACCCAGCCTAAACAGCCTCTCCAACTTGACAGCAAAtggtgttgttgccgctgctgctgccgccgctgcggcggctgctgctgctgctgctgctggtgcgcAGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGCGACGGACAACTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGTACTgtagttggagttggagttggtggagctggtggtggtggtggtggtggtgctggagGTGGAACTGcatcagttgctgctgttgctgccggcaAGCATAGTCCACAGACGCGCAACAAGACGCCAACGCCAGCaatggttgctgctgccgccgccgcagctgcggctgctgctgcctcgctGCAGGTGGCACCACCGCAACCCTTCCTAGCGCTGCCCACTAATCCGATTATCATAGTGCCCTACTCGCTTATACGTGCTGCCAGCTTGATACCGGGACCACTCACAACTTCTACGTTGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACGGCTCTAAACATAAATACGCTGGGGGGCAGTGCCACGCCTACGCCTACGCCTATGCCCAGCAGCAATCAGATACCGATGCCCGCTTTAGAGCCAGATCGTCCAACTCCTGTGAGCATTTCGAGCAACCTGGAAACGGAACCCAAGAAAAGTCCAGCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACGCCACTGGATTTATCGCTAAGACGCTCGCCAATCGCAGCGCTGTTGCAGCGTCAGCGTCTCGCGCGCTCTGCCGCTGCATTGCTCGACGCCGAGGATGCTGCAGGCAAGGATGCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCTGGAGCTGGCAGCGCTTCGTCGATGTCACCGCCAGCCCATCATATGCTGGATAATTTGCCGCCGTTGCGCTCCATGCTGCCCTCCGATTTTAATCTCTCCGAATCGCTGCTGGCCAAAACGAATCCAGAGTTGGCCCTCAAACTggctgcggcagcagcggctgctgtgGCTGGCAGTGGCTCGGCGGAGCTGGCCAAACTAGGATTTCCAGGAGCTGGTACAGCACCCAGCAGTAGTGCTGCTGCACCATCCTCTGCACAGAATGCACCGCAGATGTATGTGAAGCAGGGCGTCTCCAAGTGCAAGGACTGCAACATTGTCTTCTGCAAATATGAGAATTACTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAAACGGGTCTGGATGGAGATGCCTCCAAAAGCGCTGTAACGCCTCCCAGTGGACTATCATCAGTTGGCGGCAATGCTGGCGCCTCCTCTGCAGAAACCACTCCAGTTGCCTATCAGCAACTAATATGCGCCGCCTGCGGCATTAAATACACCTCGCTAGATAATTTGCGTGCGCATCAGAATTACTACTGTCTGAAAGGAGGCgctgcggcagctgccacGCCAGCTgaggcagcaccagcaccacaacTGCCACTCGCCCATCCCAAGGAGAAGTGCCCGAAATGCAAGACTCATCATGAGCACGGACAGAATTGTCCACCACCCCCACCACCAGCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTGCCACGTCGAATAGTGTCAATAAATGTCCCGTTTGTGGCGTAATTAGTCCCACTGCTGCTCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGTCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATTCGCACCCATTTCGATAAGAAGACCAGCGACGTGAACGAGGAGCACTACATGACATGCATCTTTGAGGAGGATGCTGCGGCGgtggcagctgcagttgctgctccaACTCAATCCTTGAATCTAGATCTGCCCGctgtagcagcagcggcggcggcagcagcagcagctcaagaGCAACTGGAACAGCATCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTACAAGGGCAATGTGCTGCGTCACATGAAATTACTGCATCCACATGTGGCCATTAGTTCGCCCTCCATTTCACCTGAGTCGCGCGAACACGAAGCCAATCCACACGCCCTACCCGAAATAGCGCTGGTTAATGGGGAACGGGAGGCAGCAGCTGTGCCCAGCTTCCACATTAAAATGGAGGCATTGGAGGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTGGCACGCCTCTTACCCACATTAAAGCGGAGCCCATGGAACTTGGAGTAGATGTATCAGTACCATCGCTACCCCCGCCGATGGCAAATTCCCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACATTTCTTGCGCACAAGCAATTCTACTGCAAGAGCAAACCGCATCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGTGGAGGCGTCTCAATGCCGCTGCAGTCGCCCAccgagctgctgttgctccagaAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MISSQTTAATIKGDCSDTTEEMTVDSRDSKELAAHELSEEKQQQHQQHQQQQQQQLEDQAEDEQLEQQSNNSSLQPIETDMEQELEEAQAAAQDSSDQKLADNPTTTTPPRSPTPGELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNLHESRLLGPPPKPEQQPTLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSTAAGSEPPNKMSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPATPSLNSLSNLTANGVVAAAAAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGITGTVVGVGVGGAGGGGGGGAGGGTASVAAVAAGKHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPYSLIRAASLIPGPLTTSTLGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPTPMPSSNQIPMPALEPDRPTPVSISSNLETEPKKSPAEPKRKETSGIRETTPLDLSLRRSPIAALLQRQRLARSAAALLDAEDAAGKDAHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHMLDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFPGAGTAPSSSAAAPSSAQNAPQMYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQETGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSATSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAAAVAAPTQSLNLDLPAVAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHALPEIALVNGEREAAAVPSFHIKMEALEAPVATLSLVHENNNSPIGTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPHRPEANDSPSPTVGGGVSMPLQSPTELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -