Basic Information

Insect: Drosophila pullipes
Gene Symbol: ham
Assembly: GCA_035043795.1
Location: JAWNMT010000637.1:839629-864388[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.55 35 5.0 0.0 2 21 332 351 331 354 0.87

2 9 0.0083 0.52 10.7 0.1 1 23 361 384 361 384 0.92

3 9 1.7e-07 1.1e-05 25.5 1.7 1 23 390 413 390 413 0.96

4 9 3.3e-07 2.1e-05 24.6 1.5 1 23 419 441 419 441 0.97

5 9 8.4e-05 0.0053 17.0 3.8 1 23 447 469 447 469 0.97

6 9 0.0018 0.12 12.8 2.0 2 21 477 496 476 497 0.94

7 9 6.5e-09 4.1e-07 30.0 1.3 1 23 990 1012 990 1012 0.99

8 9 3.4e-07 2.2e-05 24.5 0.9 1 23 1018 1041 1018 1041 0.97

9 9 4.4e-05 0.0028 17.9 6.8 1 23 1047 1069 1047 1069 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.55	35	5.0	0.0	2	21	332	351	331	354	0.87
2	9	0.0083	0.52	10.7	0.1	1	23	361	384	361	384	0.92
3	9	1.7e-07	1.1e-05	25.5	1.7	1	23	390	413	390	413	0.96
4	9	3.3e-07	2.1e-05	24.6	1.5	1	23	419	441	419	441	0.97
5	9	8.4e-05	0.0053	17.0	3.8	1	23	447	469	447	469	0.97
6	9	0.0018	0.12	12.8	2.0	2	21	477	496	476	497	0.94
7	9	6.5e-09	4.1e-07	30.0	1.3	1	23	990	1012	990	1012	0.99
8	9	3.4e-07	2.2e-05	24.5	0.9	1	23	1018	1041	1018	1041	0.97
9	9	4.4e-05	0.0028	17.9	6.8	1	23	1047	1069	1047	1069	0.98

Sequence Information

Coding Sequence: ATGTTATTCGATCGTTATATTATATCAGGCTCTAACGGCGACGATTACGATCCGAGCGTCGTGCgccatcatcaccatcatcatcaccactTGGATCACAGCAGTGGGGCGCCGGCATTTGCACCATTGCCGCCGGCACATCTAACCTCCGGTCAGACGAGGCCCGAGGAATCGTTTGGTCGCCACCTGCCGCCAACGATATCCCCGCCACCAGCAACGCtccagcatcaacagcagcagcagcagcaacagctgcaacattcACCGCCCACGCTGCCGCCTGCCTCAGCGTCCGTCTCCAACGGTTCCAGCATGGAGCATCTGTTCAATGACAAGGCGCAGGCGGAACGCTTTCTGCTGGAGATGGCGCGTCTGCGCGAACCCGTCTGTGATCTGGATATACGTGATACTGGCGTCTATGCCAAGACACATCTGCCCCGAGGCACCCGCTACGGACCCTTTCCCATGCGACTCTGCCAGCAGCCCAGCGATCGACACTTGGCCTGGGAGGTGATTGCCGGCCCATTGTTTCACGGTTGGCTGGAACCCTCATCGGATGTGGCCACATGGCTGAAAAAAATACGCGCCGTTCAAAGTGATGAAATCGAAGAGGCTAATTTAAGGAATTTCATCATTGCCGGCTAtCTGTGGTACGAGACGAAACGGGACGTAAATGCTGGCGCTGAAATTGTTGTCGATGCCCGTCCGAAAACCCCCTACGATATCAGCGACAGTTTTATGAACGGGGCAGGGGCTGCCGGCGGCGCGGGCAGTGCAACATCGGCGGGGGCCAGCAGtacagcagccgctgcagcgacagcagcagcagcagcagcagcaactgcaatggcagcggcagcaacatccagcaacaacaacaacaatggttcGTTGCCAGGCGATGATCGCAGCGATCGTGATAATGGCTTTTATAGCGGGGACGAGAAGAAAGGCGACAACGATTTCACGGACGACGAGAACGGTTTCGATATACGCTGTGAGGTGTGTGATAATGTCTATACGGATTTAGAACGATTGGACGATCATTTAGTGGGCGCACATCATTTCAAGCGCGGAGAATTCCCCTGCGAGCTTTGTGCCCAGCGTTTCAGCCATCGTCCTTTGCTAATCAAGCACGGAGCCATCGCCCATAATAATATACGCAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGtaaaacatttgccacatcATCGGGCTTAAAGCAGCATCAGCACATCCACTCATCGGTTAAGCCGTTCGCCTGCGAGGTGTGCTTCaaggcgtatacgcaattctCCAATCTGTGTCGCCACAAGCGGATGCACGCCGACTGTCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACATCGCTGTCCAAGCACAAGAAGTTCTGCGATACCTCCGACAGTTTtcgcagccagcagcagagtCGCCTGCAACACGCCCACGAACGCCACCatcaccagcatcagcatcatcagcagcagcagcagcagcaactctcGCAGCCGCCATCACTTCTGTTGCCACCCGGTGCCCATCAGCGACTTGCCGCCGAGACATCCAATTCGGCCATGGCCACGCCACCAAATCGCATATTTATGATGCATCCGACATCGTCGTTCTTTGCTGGCTTTCCCAATTACGGGCTGCATGGCTTATTTCCCGGCTTCCAGCAGGCTGGCAATTTTCCGCTATCACACATGTTTCCCAATTCGCCGCTGGGCGATATGAGTCGCGGCCTGCCGCCAATTGTCTCCCCAACAGCCGCAttccaacagcagctgcagtcagCGATGACAATGAAAACCGAATCGCCACGTTTGAAACGCGACTCCAGCACACCGGAGCGTAAGCCCATCAAATCGGAGCTACATCCCTCCGACGAGGAGTCCAATTCGCTCAGCTACGACGAGCTCAAGCTGAAGTCGAGCAAGTTGCAGCAGGAGTCGGGCAAGGTGAAGCGGGAACTTAAATCGGAGGCCAGTTGCACCCAGCAAGCCGACGAGGACAGCGATCATAATAATAGTGACAATGATCACGATAATGATATTGAAAATGATAGGAAATCGATTGACATTGTTAGCACTCCGCCGCCAGCGGAAACGCAACTGAAGACCGAACCGGAAACGGCGGATGTGGACAAGAGCAGCGCTGAACTGCCGCTGGATCTGTCCATCAGTCGCAAGCGTCGCAGTTCGCTGTGCGCCGCCTCCACGCCCGCCCCGCTCTCCATATCGCTGTCGAGTCGCGAGCCATCGCCCGAGCTGGACgccgatgaggatgaggaagAGGATGAGGACGAAGTGGAGCTGCTGGCGCCGCCGGCAAAGCAACCAAAGCACAGTTCCGGCGAATCGAGCACTTCCCGTCAGTCGTACAAGGGCTGCAGTCCGGTGCCAAGTGCAAGTGCCTCTCCCGGACCCACGCCCTCACCGTCGCCACCCATCAGCACTGGCGGCGAGTTGAGCAGCATGTCGGAGAGTGCCGCTGCCaatgcaacggcaacggcaacggcaacggcaacggcatcggcagctgccgcagccgcagcagcagcggccgccTCAGCGATGGCCTGTCCACGGCAACTACatccgcagctgctgctggaggagcTCTACCGTACGCGATTCCCAACGCAGCCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCACTAAAGTCGCCAGCGATGGGTGCCGCACATGCGCCCATCAGTGGCGGCGGCTCGCGTCATCTGCCGTTTCCGCCCGAGCATAATTTCCACGAGGCACTCCGTGCCGCTGGCTTGGCGGCCGCTGCCGTCCGTCCGCCGACAGCGTGCAACGCCAGTGGCAAGCTAAAGGATCGCTATACGTGCAAATTCTGTGGCAAGGTGTTTCCACGTTCCGCGAATCTAACACGGCATCTGCGCACCCACACCGGCGAACAGCCGTACACGTGCAAGTATTGCGATCGTGCCTTCAGCATCTCATCGAATCTGCAGCGTCATGTGCGCAACATCCACAACAAGGAGCGACCATTTCGCTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTCAAGAAGCACGAGGCAGATGCTGGCGGCTTCGAGTACAACGATTCGCCCAGTTCGAATGAGGCAAATGATCGCGATGAGGCCTGCTTCGATGATATCCGTTCGTTTATGAAACGCGTCTACACGCCCACCAGTTTGGGCGGGGCGGATGGGGATACGGAGGAGTATGCGGGCAGTGATGATCAGTTGTCCGTTTCCACGCGTCAGTCTGCCAACTTTGACAAGGAGCTGCTCTCAAAtggcaacatcatcaacatcaacaacaacaatagcagcaacaataacaacaacaatagcaacaacaacaacaatagcaacagcagcagcaacaatcagaCTTTAAATACATCGGAAACAATTGCCGTGAGCACCTAA
Protein Sequence: MLFDRYIISGSNGDDYDPSVVRHHHHHHHHLDHSSGAPAFAPLPPAHLTSGQTRPEESFGRHLPPTISPPPATLQHQQQQQQQQLQHSPPTLPPASASVSNGSSMEHLFNDKAQAERFLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSSDVATWLKKIRAVQSDEIEEANLRNFIIAGYLWYETKRDVNAGAEIVVDARPKTPYDISDSFMNGAGAAGGAGSATSAGASSTAAAAATAAAAAAATAMAAAATSSNNNNNGSLPGDDRSDRDNGFYSGDEKKGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFPCELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDTSDSFRSQQQSRLQHAHERHHHQHQHHQQQQQQQLSQPPSLLLPPGAHQRLAAETSNSAMATPPNRIFMMHPTSSFFAGFPNYGLHGLFPGFQQAGNFPLSHMFPNSPLGDMSRGLPPIVSPTAAFQQQLQSAMTMKTESPRLKRDSSTPERKPIKSELHPSDEESNSLSYDELKLKSSKLQQESGKVKRELKSEASCTQQADEDSDHNNSDNDHDNDIENDRKSIDIVSTPPPAETQLKTEPETADVDKSSAELPLDLSISRKRRSSLCAASTPAPLSISLSSREPSPELDADEDEEEDEDEVELLAPPAKQPKHSSGESSTSRQSYKGCSPVPSASASPGPTPSPSPPISTGGELSSMSESAAANATATATATATASAAAAAAAAAAASAMACPRQLHPQLLLEELYRTRFPTQPFHFLGQMGGRPGFESLKSPAMGAAHAPISGGGSRHLPFPPEHNFHEALRAAGLAAAAVRPPTACNASGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSANFDKELLSNGNIININNNNSSNNNNNNSNNNNNSNSSSNNQTLNTSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01327310;
90% Identity: iTF_00513601;
80% Identity: -