Basic Information

Insect: Drosophila pseudotakahashii
Gene Symbol: ken1
Assembly: GCA_035046095.1
Location: JAWNOE010000189.1:4936628-4938779[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 9e-05 0.0076 17.0 3.2 2 23 188 209 187 209 0.97

2 12 0.0063 0.53 11.1 0.1 1 23 215 240 215 240 0.92

3 12 0.12 10 7.1 0.1 3 23 249 272 247 272 0.92

4 12 0.00078 0.066 14.0 0.5 2 23 285 306 284 306 0.96

5 12 1e-05 0.00084 20.0 0.6 1 23 313 335 313 335 0.98

6 12 0.0096 0.81 10.6 0.2 1 23 341 363 341 363 0.98

7 12 0.016 1.4 9.9 4.0 1 23 369 392 369 392 0.97

8 12 0.011 0.9 10.4 4.0 1 23 398 420 398 420 0.96

9 12 0.00091 0.076 13.8 2.9 2 23 427 448 426 448 0.96

10 12 0.0003 0.025 15.3 1.1 3 23 537 558 535 558 0.95

11 12 0.0032 0.27 12.1 1.1 1 19 564 582 564 586 0.95

12 12 1e-06 8.4e-05 23.1 0.8 1 23 592 614 592 614 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	9e-05	0.0076	17.0	3.2	2	23	188	209	187	209	0.97
2	12	0.0063	0.53	11.1	0.1	1	23	215	240	215	240	0.92
3	12	0.12	10	7.1	0.1	3	23	249	272	247	272	0.92
4	12	0.00078	0.066	14.0	0.5	2	23	285	306	284	306	0.96
5	12	1e-05	0.00084	20.0	0.6	1	23	313	335	313	335	0.98
6	12	0.0096	0.81	10.6	0.2	1	23	341	363	341	363	0.98
7	12	0.016	1.4	9.9	4.0	1	23	369	392	369	392	0.97
8	12	0.011	0.9	10.4	4.0	1	23	398	420	398	420	0.96
9	12	0.00091	0.076	13.8	2.9	2	23	427	448	426	448	0.96
10	12	0.0003	0.025	15.3	1.1	3	23	537	558	535	558	0.95
11	12	0.0032	0.27	12.1	1.1	1	19	564	582	564	586	0.95
12	12	1e-06	8.4e-05	23.1	0.8	1	23	592	614	592	614	0.98

Sequence Information

Coding Sequence: ATGGGCACCAGGGAGCTCCAGTACTCCGTCCACTCGCTGTGTCGCATCTGCCTTAGCCACCTGGAGCAGGGTGTTGGCcatgatcttttcctggttcCAGATCTGGTCAGGAAACTGGTTTCCGTGACTTCCTTGGAGGCGGATCAAAGCGACGGTTTCCCAAACAAGCTGTGCGCCCTGTGCTTCACCAGGTTGAACGACCTGCACGATTTTCGGGAACTCTGTGCGGGATCCATCAAGCGTTTTAAGGAAATGGTGGCCAGCAATAGGATTCTGCCCATGGGCGATTTTGAGCCCATTGCGGAGGATTCTGAGACAATGGGAAGGCAGGAGGAGCAGGCCAGCTTTGATCCCCTGCTAAATCACAAGATGGAGCTGATTGAGAACGAGGAAGAAGTCTTCAAGATGCTGAACTCTGTGGACAGGGAACAGGAGGAACAAAGCCAAGTGGATTCATCCAGTGAAGAAGagaacgaggaggaggagaagaagcTGTCGGATGGGTTCTCCAGCGATGATGAACAACCCTTGGCCAGACGGCGGAGGATTCCCGGCCTCATAACCTGCCCCATCTGCCAGCAGAAGTTCAAGAAGCAGTCAAAGTACGAGGAGCACATGAAGCACCACAACGACCTGCTGCCCTTTCAGTGCGAGGAGGAAAGCTGCCGCAAGGGCTTCACCACAGCCGGTGCACTGCGTCTCCACGTGGACTATGCGCACACCAAGAAGGCCGATGAGATTCCCTGCACTGTGGAGGGCTGTAGGTTACTGTTTCCTCGTCTCCGCCTGCTGACCATCCACCTGAAAAAGGTTCACAATCAGGCGAGGGTCAGTGCGCCGCGGTCTGAGCAGCCTTGCGGTGAATGCGGCATGGTCTTCCGCTGTCCGGTGGCTCTGAAGAAGCACATGTACAAGCACACCGGCGCGGAGCTTCCCTATCCCTGCAATATCTGCGGCAAGGGCTTCCATATCAACAGTGCCCTGAAGAATCATCTTCTCCGGCATGCCGGGATCAAGAACTACGTGTGTCCGTACTGCGGAGTGGGCAAGACCACGCGCCAGGAGTGGAGCAAGCACCTCCTGACCCACACTCAGGAAAAGCAGTTCAAATGCCACATCTGCGATCATGCCACCCACACAAAGCGGGCTCTGGATAGCCACGTAAAGATTGTGCACGAGAAGATCCGGAACTTTGCCTGCCAGTATTGTGGGAAGACCTTTGGCAAGTCGCATGCCTGCAAGATTCACGAGATGACGCACACCGGGGAGAAGCGCTGCGAGTGCAAGGTTTGTGGCAAGAAGTTCCTGTACACGGAAAGCCTGACGAAGCACCTGAAAATCCACGAAAAGAGCGTTGAGAGGGCTCTGGAAACCTATAGACAGAGGCAGGGGGATGGTGAGGCCTTGGACCGCCAAGTGGATGCTGATCAGCTGCTAAGGGTATGCGCCGAATCTGTGGCCACCATACCCAAAGATCCTCGCCGCGTGGAGCGCGTTGACCTCGCCCAACTGGCTGGAACCGTAGTGAATCCCATACCCACCGTTCAGATGCCGCCCAGCGAAGCTCCCGCACGCACCAAGTTTGTCCAGAAGGAGGGCATGCACCTGTGCCCCGGGTGCAGCCAGGGATTCAATAATCTGGGCAACATGAAGCGCCACTACAAGAGCGTCCATGAGAAGGTCAAGGACTTTGAGTGCCGCTTCTGCTCACGTCGCTTCGCCAACTCCCAGTCCCTGAAGCAACACGAGTGGATACACACTGGCGAAAAGCCGTACGAGTGCAAGGTTTGTGGCACTCATTTCCGCCAGGAAGCGGCTCTCATCCGTCACCAAAAGGTCCACGACGAAAAGCCGCCAAAGCCTCCCAGGCCACCGAAGGAAATTAGCGAAAGGGCGCGCCAGAAGGCGATGCAGAAAAGTGAGCGAAGACGTAAAGTGGAGGCTCTGCGGCAGGAAATTGCCGAGGCTGCCAAGGAGGAGCTCAAGGATTTGGAGAACCAACGGGCTCTGGAGAAGCAGCAGAACACCTACGAACAGTATCAAGCAGCGGCAGCTGGCCAGACTAATCCCGAGTCCAAGGAGGAATCCTGA
Protein Sequence: MGTRELQYSVHSLCRICLSHLEQGVGHDLFLVPDLVRKLVSVTSLEADQSDGFPNKLCALCFTRLNDLHDFRELCAGSIKRFKEMVASNRILPMGDFEPIAEDSETMGRQEEQASFDPLLNHKMELIENEEEVFKMLNSVDREQEEQSQVDSSSEEENEEEEKKLSDGFSSDDEQPLARRRRIPGLITCPICQQKFKKQSKYEEHMKHHNDLLPFQCEEESCRKGFTTAGALRLHVDYAHTKKADEIPCTVEGCRLLFPRLRLLTIHLKKVHNQARVSAPRSEQPCGECGMVFRCPVALKKHMYKHTGAELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHLLTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKIRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGDGEALDRQVDADQLLRVCAESVATIPKDPRRVERVDLAQLAGTVVNPIPTVQMPPSEAPARTKFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCSRRFANSQSLKQHEWIHTGEKPYECKVCGTHFRQEAALIRHQKVHDEKPPKPPRPPKEISERARQKAMQKSERRRKVEALRQEIAEAAKEELKDLENQRALEKQQNTYEQYQAAAAGQTNPESKEES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548237;
90% Identity: iTF_00486730;
80% Identity: -