Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: -
Assembly: GCA_009870125.2
Location: CM020868.1:26820155-26824087[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 8.6e-05 0.0065 17.0 0.1 1 23 175 198 175 198 0.96

2 13 0.0018 0.14 12.9 3.1 2 23 247 269 243 269 0.90

3 13 0.0078 0.59 10.9 0.8 1 23 358 381 358 381 0.93

4 13 0.34 26 5.7 5.4 2 23 430 452 429 453 0.95

5 13 0.0015 0.11 13.2 0.6 1 23 515 538 515 538 0.88

6 13 0.00072 0.054 14.1 3.3 2 23 589 611 589 611 0.96

7 13 0.00058 0.044 14.4 0.0 1 23 696 719 696 719 0.95

8 13 0.00072 0.055 14.1 0.2 1 23 779 802 779 802 0.93

9 13 0.0012 0.091 13.4 2.2 2 23 852 874 851 874 0.97

10 13 0.0034 0.26 12.0 3.8 1 23 966 988 966 989 0.94

11 13 0.055 4.1 8.2 1.5 1 21 1041 1061 1041 1062 0.95

12 13 1.9 1.5e+02 3.3 0.2 2 19 1103 1120 1102 1127 0.74

13 13 0.88 67 4.4 1.8 1 23 1144 1168 1144 1168 0.68

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	8.6e-05	0.0065	17.0	0.1	1	23	175	198	175	198	0.96
2	13	0.0018	0.14	12.9	3.1	2	23	247	269	243	269	0.90
3	13	0.0078	0.59	10.9	0.8	1	23	358	381	358	381	0.93
4	13	0.34	26	5.7	5.4	2	23	430	452	429	453	0.95
5	13	0.0015	0.11	13.2	0.6	1	23	515	538	515	538	0.88
6	13	0.00072	0.054	14.1	3.3	2	23	589	611	589	611	0.96
7	13	0.00058	0.044	14.4	0.0	1	23	696	719	696	719	0.95
8	13	0.00072	0.055	14.1	0.2	1	23	779	802	779	802	0.93
9	13	0.0012	0.091	13.4	2.2	2	23	852	874	851	874	0.97
10	13	0.0034	0.26	12.0	3.8	1	23	966	988	966	989	0.94
11	13	0.055	4.1	8.2	1.5	1	21	1041	1061	1041	1062	0.95
12	13	1.9	1.5e+02	3.3	0.2	2	19	1103	1120	1102	1127	0.74
13	13	0.88	67	4.4	1.8	1	23	1144	1168	1144	1168	0.68

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTGTGGACGTCCATGTTCTCGGCAGACTtcgaggagggggaggaggagattGAGCAATATGCGAATGAAAACGGTCTGGACAGCAATCCCGCCGGCGACAGTGACGACATTCTGCCCGAGGGCGATggcgacgacgaggacgaagaaaacgaggaggaggacgacgatgatgatgataatgatgtgGAGGATGATGCGGAGGAGGAGACCGGCCGTGACAGTGGGAAAACAAAAGAGCCCGATCAGGATGATGATGCCATATTTCAGTTCGATCTGGAGCCGATTGTAGTCATTGGAGAGCCACAGGCTCAGCCACCGTTGCTGGCGCCTCCGGGTCCACTTGGCGCGCCGCCTGTGCGTCCCATGCATCGGCACTCACTGCCCAGGGCCAGCCAGGGTCGGCCCAAGGAGGGGCGTCTTTCGGGCGTGCTCACGCGGCCCACCACCTCGCAGATCAATGCAACAGATGCGAACGGGATTCCCATCAACTATGAGCTGGGCGTCATCTACATCTGCCCCGCGTGCGGAGCGGAATTCCGGCAGCAGGATCTCTGGAAACGCCACATGAACCAGATGCACCAGTTCAACACGCGCCGCGGCCTCAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGCAACAAGCGCATCGCCATGCATAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCATCTGCCGTTCAGGTGCACCAAGTGCTACATCTGCAAACGGGAGTACAAATACAGACAAGACCTGATGGTCCACCTGAGGATGGTCCATTGCGACGAGGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGCCGCAAGACGCGGGTGCGGGAGCCGCGCACAGAACAAATGCAACGCAAGGACCCGTTCCCGGAAGAGGATGAAGAGCGGAACGATCTTCTCGAGCCGGAGACTGAGACTGTGCCACCTATGCTGGAAGAGGAAGCCCCGCCGAAGCGCAGGAAGAAGCGCTACCAAGGAGGTCCCTCCGGCGATGGAGGTGCGGATCTTTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACGGAGTGCGACACGCACGCCCAGTGGAGTCAGCACATCGAGTTTGTCCATGACTACGTCAGTCGCAGGGGGCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCATCCCCAACACCATTAAGACGCTGCGGGCGCACAAGTTCACGCATCTGTCGCAGCCCGAGTGGCTCCGCTGCAAGCTGTGCTACAAGGGCTACACGGAGCACCACGAGCTGGTCAGTCATCTGCTGAAGCAGCACCACCTGGAGTCGCTGATGCCCGAGGATTCGCCGGATCCATCACCCGTCAAAAAGACAGACGGAGGCGACGACTGGGAGGACAATGGAAATGGGAGCGTCTTCGATGACGTGTCACCGCACTTTGAAGATGTCCCGCGGCGGGGAGGCCGTATCGGGAGCGATGACATGTATGAGCCCCACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAATTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGCAGGTGCACGGCATGAACGACGTGACGAAGCTCAACTTTGAGATAATCAACGATCGCCAGCTGAAGTGCACGGAATGCGCCAAGATCATAACGAACGCCTACGGCATACAGAATGCCCAGCAGCACAGGATCACGCACCTGCCATTCAAGGCGTATGCCAGGTGCCGCAAATGCCACAAGTCTTACACGGACCGCAAGGGTCTGGTCAAGCACCTGGCCACCTACCACCGTGTGGGCTACGTGCCGCGCAAAACCCTGAAAAGAGGCGGACGACCAGCCGCGCCGTTTGCGTCGCCCAAGCAGCAGCGCAGACAAATTGTGACCTTGGGAAAAGAGACCTACGAGATCATCTTCCTGGACGAAGAGCTGATGCACTCAAGTGTCGACGAGGAGAACGACTTCGGAGAGCAGATGCAGATGGCGGATGAGGAGGACTTGCCCACTGTCAGTGCTGGCGTACTGCCGCCCAGCCCGAATCGCTACAAGTGCGTGGAATGCGGAACGCTGTTCCCCACCCAAGTGGCTCTCAAGTTGCACATCAGCGAGGCACATACGTTCCGGGACCCCCCTCAGTACGGGGGATCCAAGAAGCTGGACAAATCCCAGGGCAAAGAGGAGTCGCCCAAGAAGAGGAGACTAGGAGCgggtccagcagcagcactgacACCATCATCTTCGCCAGCGGCCACAAGCACCCCATCATCGGGCACCGTAGAGCAGAACTACATATTTCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACGCAGTTCGAATGGCGCCGCCACATCAACGAGGCCCACAACTTTGACAAGCGGCAGTATCTGAATATGCGCCAACTCGACAAGTACCGATACCAGTGCACCCAGTGCAACGACATTGTGTGCAACTCCAAGTTGAAGGGGCTGCAGGACCACCACTTTCGCCATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACCTGCTACAACCACAAGCCCAACATTGCCGCTCATCTGAGGACGCGGCACAACATCTACGAGCGCGAAACGCCCTGGCGGGAGCTACAGACCAAGCCCCAGTACTCTTATGTTCAGTCCAAGGAAAAGGACAGGGACACGGCCGTCAAGAGCAGGCCGCAATCACCCTCGCATGCAGTTGTGCCCTCCTCATCAGGCTCATCCAGTACCAGCAGTCGCCCACTCTGGCCACAGTCCGAGAAGCGTCCGACACGGCCGGCCGGTCTCAACACCCTGGAGGACAGCATCTCGTACCACAATGCGGTGGACATGGACTTCATCACCTACTACTGCCCCAAGTGCAACAAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCACCACAACTTCAACAGCCGCGAGGGCCTGAACTTCCGGCAGATCGACATCCACCACTACTTATGCCTGGAGTGCTACAAGCGTGTCACCGTCACCCATACCAAGGGCGCCATCGGGCAGCTCCAGTCGCACAAGTTCCGCCACCTGCCCTACCGCTCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTGCGCAAGCAGATGTTCTTCAAGCATCTCAATCGGGACACCAATCGGTGCGATAACAAGCCCAGCGCCGCAGAGGTGTTTGATGACGAGGAGCAGGACGCGATTGGCGTCACCGCCGCGGAAGATGAAGACGTTGAAGCCTCTGCCTATCGACTGATGTGCCCCCAGTGCGGCGACGACTTCACCACCTCCAACCAGGCGGTGTGGCACAACCACCTCAACGTCTCGCACGGCCTGGACAAGCAGCTTCTGCACATTCGGAAGGTAGGCGAGGGGCTCTACCGCTGCCACGACTGCAACGAGGAGTTGGCTACGAAGAGCAGGCGGGtcctgcagcagcaccgcTTCAAGCATATGCCCCATTCCGGCTACATTCGTTGCCAACTTTGCGAGAGCGGGACGGATGAGAAGGCGGCTGAAGTGCACAGCATGCGGGAGCTGCATCAGCACATCCGCGAGCACCATCCGGCAGTGGACGAGAGCGACGAGAGGATGCTGAAGGTGCGCCAGCTAatggacgaggaggagaccGACGAGGACCGTCAGCCAACAGCAAACAGTGACAATGAATCAGGCTCGACGCCAAACAATGGTCCATATATGCCGCTACCGCCGCATTTACTGGACGAGGTGGAGGATTTGGATTTCGAGGATCAGTATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSADFEEGEEEIEQYANENGLDSNPAGDSDDILPEGDGDDEDEENEEEDDDDDDNDVEDDAEEETGRDSGKTKEPDQDDDAIFQFDLEPIVVIGEPQAQPPLLAPPGPLGAPPVRPMHRHSLPRASQGRPKEGRLSGVLTRPTTSQINATDANGIPINYELGVIYICPACGAEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRKDPFPEEDEERNDLLEPETETVPPMLEEEAPPKRRKKRYQGGPSGDGGADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLSQPEWLRCKLCYKGYTEHHELVSHLLKQHHLESLMPEDSPDPSPVKKTDGGDDWEDNGNGSVFDDVSPHFEDVPRRGGRIGSDDMYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFEIINDRQLKCTECAKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPRKTLKRGGRPAAPFASPKQQRRQIVTLGKETYEIIFLDEELMHSSVDEENDFGEQMQMADEEDLPTVSAGVLPPSPNRYKCVECGTLFPTQVALKLHISEAHTFRDPPQYGGSKKLDKSQGKEESPKKRRLGAGPAAALTPSSSPAATSTPSSGTVEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQSKEKDRDTAVKSRPQSPSHAVVPSSSGSSSTSSRPLWPQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPSAAEVFDDEEQDAIGVTAAEDEDVEASAYRLMCPQCGDDFTTSNQAVWHNHLNVSHGLDKQLLHIRKVGEGLYRCHDCNEELATKSRRVLQQHRFKHMPHSGYIRCQLCESGTDEKAAEVHSMRELHQHIREHHPAVDESDERMLKVRQLMDEEETDEDRQPTANSDNESGSTPNNGPYMPLPPHLLDEVEDLDFEDQYLLG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575176; iTF_00536356;
90% Identity: iTF_00536356; iTF_00575176;
80% Identity: -