Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:27208275-27215020[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 8e-05 0.0045 17.0 0.1 1 23 175 198 175 198 0.96

2 13 0.0017 0.096 12.9 3.1 2 23 247 269 243 269 0.90

3 13 0.0074 0.41 10.9 0.8 1 23 358 381 358 381 0.93

4 13 0.32 18 5.7 5.4 2 23 430 452 429 453 0.95

5 13 0.0014 0.077 13.2 0.6 1 23 517 540 517 540 0.88

6 13 0.00067 0.038 14.1 3.3 2 23 591 613 591 613 0.96

7 13 0.00054 0.03 14.4 0.0 1 23 698 721 698 721 0.95

8 13 0.00068 0.038 14.1 0.2 1 23 781 804 781 804 0.93

9 13 0.0011 0.064 13.4 2.2 2 23 854 876 853 876 0.97

10 13 0.0032 0.18 12.0 3.8 1 23 968 990 968 991 0.94

11 13 0.051 2.9 8.2 1.5 1 21 1043 1063 1043 1064 0.95

12 13 6.3 3.6e+02 1.6 0.9 2 19 1105 1122 1104 1129 0.68

13 13 0.83 47 4.4 1.8 1 23 1146 1170 1146 1170 0.68

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	8e-05	0.0045	17.0	0.1	1	23	175	198	175	198	0.96
2	13	0.0017	0.096	12.9	3.1	2	23	247	269	243	269	0.90
3	13	0.0074	0.41	10.9	0.8	1	23	358	381	358	381	0.93
4	13	0.32	18	5.7	5.4	2	23	430	452	429	453	0.95
5	13	0.0014	0.077	13.2	0.6	1	23	517	540	517	540	0.88
6	13	0.00067	0.038	14.1	3.3	2	23	591	613	591	613	0.96
7	13	0.00054	0.03	14.4	0.0	1	23	698	721	698	721	0.95
8	13	0.00068	0.038	14.1	0.2	1	23	781	804	781	804	0.93
9	13	0.0011	0.064	13.4	2.2	2	23	854	876	853	876	0.97
10	13	0.0032	0.18	12.0	3.8	1	23	968	990	968	991	0.94
11	13	0.051	2.9	8.2	1.5	1	21	1043	1063	1043	1064	0.95
12	13	6.3	3.6e+02	1.6	0.9	2	19	1105	1122	1104	1129	0.68
13	13	0.83	47	4.4	1.8	1	23	1146	1170	1146	1170	0.68

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTGTGGACGTCCATGTTCTCGGCAGACTTcgaggagggggaggaggagatTGAGCAATATGCGAATGAAAACGGTCTGGACAGCAATCCCGCCGGCGACAGTGACGACATTCTGCCCGagggcgatggcgacgacgaggacgaagaaaacgaggaggaggacgacgatgatgatgataatgatgtgGAGGATGATGCGGAGGAGGAGACCGGCCGTGACAGTGGGAAAACAAAAGAACCCGATCAGGATGATGATGCCATATTTCAGTTCGATCTGGAGCCGATTGTAAGCATTGGAGAGCCACAGGCTCAGCCACCGTTGCTGGCGCCTCCGGGTCCACTTGGCGCGCCGCCTGTGCGTCCCATGCATCGCCACTCACTGCCCAGGGCCAGCCAGGGTCGGCCCAAGGAGGGGCGTCTTTCGGGCGTGCTCACGCGGCCCACCACCTCGCAGATCAATGCAACCGATGCGAACGGGATTCCCATCAACTATGAGCTGGGCGTCATCTACATCTGCCCCGCGTGCGGAGCGGAATTCCGGCAGCAGGATCTCTGGAAACGCCACATGAACCAGATGCACCAGTTCAACACGCGCCGCGGCCTCAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGCAACAAGCGCATCGCCATGCATAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCATCTGCCGTTCAGGTGCACCAAGTGCTACATCTGCAAACGGGAGTACAAATACAGACAAGACCTGATGGTCCACCTGAGGATGGTCCATTGCGACGAGGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGACGCAAGACGCGGGTGCGGGAGCCGCGCACAGAACAAATGCAACGCAAGGACCCGTTCCCAGAGGAGGATGATGAGCGGAACGATCTTCTCGAGCCGGAGACTGAGACTGTGCCACCTATGCTGGAAGAGGAGGCCCCGCCGAGGCGCAGGAAGAAGCGCTACCAAGGAGGTCCCTCCGGCGATGGAGGTGCGGATCTTTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACGGAGTGCGACACGCACGCCCAGTGGAGTCAGCACATTGAGTTTGTCCACGACTACGTCAGTCGCAGGGGGCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCATCCCCAACACCATTAAGACGCTGCGGGCGCACAAGTTCACGCATCTGTCGCAGCCCGAGTGGCTCCGCTGCAAGCTGTGCTACAAGGGCTACACGGAGCACCACGAGCTGGTCAGTCATCTGCTGAAGCAGCACCACCTGGAGTCGCTGATGCCCGAAGATTCGCCTGATCCATCACCCGTCAAAAAGACagacggaggcggaggcgACGATTGGGAGGACAATGGAAACGGGAGCGTCTTCGATGACGTGTCGCCGCACTTTGAAGATGTCCCGCGGCGGGGAGGCCGTATCGGGAGCGATGACATGTATGAGCCCCACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAATTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGCAGGTGCACGGCATGAACGACGTGACGAAGCTCAACTTTGAGATAATCAACGATCGCCAGCTGAAGTGCACGGAATGCGCCAAGATCATAACAAACGCCTACGGCATACAGAATGCCCAGCAGCACAGGATCACACACCTGCCATTCAAAGCGTACGCCAGGTGCCGCAAGTGCCACAAGTCTTACACGGACCGCAAGGGTCTGGTCAAGCATCTGGCCACCTACCACCGTGTGGGCTACGTGCCGCGCAAAACCCTGAAAAGAGGCGGACGACCAGCCGCGCCGTTTGCGTCGCCCAAGCAGCAGCGCAGACAAATTGTGACCTTGGGAAAAGAGACCTACGAGATCATCTTCCTGGACGAAGAGCTGATGCACTCAAGTGTCGACGAGGAGAACGACTTCGGAGAGCAGATGCAGATGGCGGATGAGGAGGACTTGCCCACTGTCAGTGCTGGCGTACCGCCGCCCAGCCCGAATCGCTACAAGTGCGTGGAATGCGGGACGCTGTTCCCCACCCAAGTGGCTCTCAAACTGCACATCAGCGAGGCACATACGTTCCGGGACCCCCCTCAGTACGGGGGATCCAAGAAGCTGGACAAATCCCAGGGCAAAGAGGAGTCGCCCAAGAAGAGGAGACTAGGAGCGggtccagcagcagcactgaCACCATCATCATTGCCAGCGGCCACAAGCACTCCATCGTCGGGCACCGTAGAGCAGAACTACATATTTCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACGCAGTTCGAATGGCGCCGCCACATCAACGAGGCCCACAACTTTGACAAGCGGCAGTATCTGAATATGCGCCAACTCGACAAGTACCGATACCAGTGCACCCAGTGCAACGACATTGTGTGCAACTCCAAGTTGAAGGGGCTGCAGGACCACCACTTTCGCCATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACCTGCTACAACCACAAGCCCAACATTGCCGCTCATCTGAGGACGCGGCACAACATCTACGAGCGCGAAACGCCCTGGCGGGAGCTACAGACCAAGCCCCAGTACTCTTATGTTCAGTCCAAGGAAAAGGACAGGGACACGGCCGTCAAGAGCAGGCCGCAATCACCCTCGCATGCAGTTGTGCCCTCCTCATCAGGCTCATCCAGTACCAGCAGTCGCCCACTCTGGCCGCAGTCCGAGAAGCGTCCGACACGGCCGGCCGGTCTCAACACCCTGGAGGACAGCATCTCGTACCACAATGCGGTGGACATGGACTTCATCACCTACTACTGCCCCAAGTGCAACAAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCACCACAACTTCAACAGCCGCGAGGGCCTGAACTTCCGGCAGATCGACATCCACCACTACTTATGCCTGGAGTGCTACAAGCGTGTCACCGTCACTCATACCAAGGGCGCCATCGGGCAGCTCCAGTCGCACAAGTTCCGCCATCTGCCCTACCGATCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTGCGCAAGCAGATGTTCTTCAAGCATCTCAATCGGGACACCAATCGGTGCGATAACAAGCCCAGCGCCGCAGAGGTGTTTGATGACGAGGAGCAGGACGCGATTGGCGTCACCGCCGCGGAAGATGAAGACGTTGAAGCCTCTGCCTATCGACTGATGTGCCCCCAGTGCGGCGACGACTTCACCACCTGCAACCAGGCGGTGTGGCACAACCACCTCAACGTCTCGCACGGCCTGGACAAGCAGCTTCTGCACATTCGGAAGGTAGGCGAGGGGCTGTACCGCTGCCACGACTGCAACGAGGAGTTGGCTACGAAGAGCAGGCGGGTCCTGCAGCAGCACCGCTTCAAGCATATGCCCCATGCCGGCTACATTCGTTGCCAACTTTGCGAGAGCGGGACGGAAGAGAAGGCGGCTGAAGTGCACAGCATGCGGGAGCTGCATCAGCACATCCGCGAACACCATCCGGCAGTGGACGAGAGTGACGAGAGGATGCTGAAGGTGCGCCAGCTAATGGACGAGGAGGAGACCGACGAGGACCGTCAGCCAACAGCAAACAGTGACAATGAATCAGGCTCGACGCCAAACAATGGTCCATATATGCCGCTACCGCCGCATTTACTGGACGAGGTGGAGGATTTGGATTTCGAGGATCAGTATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSADFEEGEEEIEQYANENGLDSNPAGDSDDILPEGDGDDEDEENEEEDDDDDDNDVEDDAEEETGRDSGKTKEPDQDDDAIFQFDLEPIVSIGEPQAQPPLLAPPGPLGAPPVRPMHRHSLPRASQGRPKEGRLSGVLTRPTTSQINATDANGIPINYELGVIYICPACGAEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRKDPFPEEDDERNDLLEPETETVPPMLEEEAPPRRRKKRYQGGPSGDGGADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLSQPEWLRCKLCYKGYTEHHELVSHLLKQHHLESLMPEDSPDPSPVKKTDGGGGDDWEDNGNGSVFDDVSPHFEDVPRRGGRIGSDDMYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFEIINDRQLKCTECAKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPRKTLKRGGRPAAPFASPKQQRRQIVTLGKETYEIIFLDEELMHSSVDEENDFGEQMQMADEEDLPTVSAGVPPPSPNRYKCVECGTLFPTQVALKLHISEAHTFRDPPQYGGSKKLDKSQGKEESPKKRRLGAGPAAALTPSSLPAATSTPSSGTVEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQSKEKDRDTAVKSRPQSPSHAVVPSSSGSSSTSSRPLWPQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPSAAEVFDDEEQDAIGVTAAEDEDVEASAYRLMCPQCGDDFTTCNQAVWHNHLNVSHGLDKQLLHIRKVGEGLYRCHDCNEELATKSRRVLQQHRFKHMPHAGYIRCQLCESGTEEKAAEVHSMRELHQHIREHHPAVDESDERMLKVRQLMDEEETDEDRQPTANSDNESGSTPNNGPYMPLPPHLLDEVEDLDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581100;
90% Identity: iTF_00581100;
80% Identity: -