Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: -
Assembly: GCA_009870125.2
Location: CM020868.1:21376124-21379318[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.1e-05 0.0038 17.7 4.8 1 23 175 198 175 198 0.97

2 16 0.0025 0.19 12.4 2.4 1 23 244 267 244 267 0.95

3 16 0.0054 0.41 11.4 5.9 1 23 332 355 332 355 0.96

4 16 0.00069 0.052 14.2 1.1 2 23 413 434 412 434 0.97

5 16 7.1 5.4e+02 1.6 1.1 1 20 547 566 547 568 0.88

6 16 0.012 0.91 10.3 0.6 1 23 577 599 577 599 0.94

7 16 0.00019 0.014 15.9 0.7 1 23 606 629 606 629 0.96

8 16 0.00079 0.06 14.0 0.8 2 23 638 659 637 659 0.95

9 16 0.0038 0.28 11.9 0.1 2 20 686 704 685 709 0.90

10 16 0.0017 0.13 12.9 1.6 1 23 744 767 744 767 0.96

11 16 3.4 2.5e+02 2.6 0.7 3 22 776 795 774 795 0.95

12 16 0.17 13 6.6 1.2 1 23 804 827 804 827 0.95

13 16 4.1e-05 0.0031 18.0 0.1 1 23 849 872 849 872 0.97

14 16 0.039 2.9 8.7 0.2 1 23 882 904 882 904 0.94

15 16 6.6e-05 0.005 17.4 3.7 1 23 910 932 910 932 0.99

16 16 6.8e-06 0.00052 20.5 3.2 1 23 938 960 938 960 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.1e-05	0.0038	17.7	4.8	1	23	175	198	175	198	0.97
2	16	0.0025	0.19	12.4	2.4	1	23	244	267	244	267	0.95
3	16	0.0054	0.41	11.4	5.9	1	23	332	355	332	355	0.96
4	16	0.00069	0.052	14.2	1.1	2	23	413	434	412	434	0.97
5	16	7.1	5.4e+02	1.6	1.1	1	20	547	566	547	568	0.88
6	16	0.012	0.91	10.3	0.6	1	23	577	599	577	599	0.94
7	16	0.00019	0.014	15.9	0.7	1	23	606	629	606	629	0.96
8	16	0.00079	0.06	14.0	0.8	2	23	638	659	637	659	0.95
9	16	0.0038	0.28	11.9	0.1	2	20	686	704	685	709	0.90
10	16	0.0017	0.13	12.9	1.6	1	23	744	767	744	767	0.96
11	16	3.4	2.5e+02	2.6	0.7	3	22	776	795	774	795	0.95
12	16	0.17	13	6.6	1.2	1	23	804	827	804	827	0.95
13	16	4.1e-05	0.0031	18.0	0.1	1	23	849	872	849	872	0.97
14	16	0.039	2.9	8.7	0.2	1	23	882	904	882	904	0.94
15	16	6.6e-05	0.005	17.4	3.7	1	23	910	932	910	932	0.99
16	16	6.8e-06	0.00052	20.5	3.2	1	23	938	960	938	960	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGCGATGCAAATGGGCGTTACTGGATCGAGACGCCGGTGGAGAAGTATGCCGAGAAGACCTTCAATCAGCTATTGCTGGAGCTAACGAAGATTGAGTTGACCATGGTCCAGGCCGAGAAATTGCCCCACTGGTTGTGCTCCAGTTGCTCCCAGAAACTGGAGAGCGCCTACGATTTTGTGTTGCAGGCGAAACAGACGCACAAACTGTGGCTGCAACAGCTAGAGGATACGGGCCAGATAATGAGCTCTGGGGGGGCCTTGGAGTGCCTGCGGGAGACCCCCATACATCTGTTCGAGATCGAGGGCGTTACCATCAAAACCGAAGCGCTAGAATCAGCGGTTGCAGATGTCGGTAACAGCTCCTCCGATCCTCTAGTCCGCACACGCATCAAAAAGCGTACCGTATTTCACTTCAGCGATACGGAGGATGACCAGGATGATGTGCCGCTAAGGCATCGCAGGACTGCCAGTCAAGCGAACAGCTTGTCAGTAAAGCTGCACAAGTGCAATCTGTGCGGCAAATCCTTCAGATATATCACAAATCTCTATCGCCACAAGAAAAGAGATCACGGCTATCCAGGGCATTCCCAGGGTGAGAGCTCCGAATCAtaccaaaacacacaaaagagcGCCGTGGCAGCGCAAGAAACTTCCAATTTGGAACAAAACGAAGATaacgatgaggatgatgataatgataacTACTACAAATGCGATCAGTGCGACAAAACCTACAAGCACATAATGGTGCTTATCAAGCACAAGCAGAATGTTCATGAAACCAATCAACTGCCAATCCAATCTGGGCCCAAGCGAAGGAACAGAAGGGACGTGGGTGAAGCAGCAAGTCCAGCTTCTTCCGGGAAATCCATACAACGAACCAGAATCAGCACAGACACCCTGGTCCATAGCCTCATCAAAGCAGTGCAACTGTCGGATGAGGATGGAAACAGCGGCACCGACAACTATTACAAGTGCGATCAGTGCCACAAATCGTACAAATACATTGTAAGCCTCAtcaagcacaagcacaaggATCATTCGGAAGCTGATAAAAACTGGGACGATGAGGACAATCAACCATTGGCCTCCACATCTGCTCGCGCCTCCGCTGCCTCAGGCTCAGGCTCTCCCACCAAGGCATCGCGAATCAATCGTCGCGTACAGGGCTTCGATCTGCATCGCTGCGAGCCGAATGGTGCGAAAGAAATTCAGTGCATGATCTGTCTGCGGAAATTCACTAAATTGCGTGAGCTGAGAGATCACCTCAGGTCGCATCCCACCGACTTTAATTTCCAGGCGCACGGTGAGCCTATCGAACGCATTGCCGAGGGATTTTTCAAGACGGCTGTGGAGTCCACTGTGGAGGGTTTGAAAAGCAGAATTCTGCACGATTTAAGGATGGGTGCCTTCGGACGCTTCTATTCCATTACCAACGAGGCGCGCTACGAGATGAGTCTGGACAGCTCCGACACGGATAGCGACGGCGATGCAGATGTTGTACTAAGGCGAAGCTATGCCTGTGAGCTATGCGACTCCCCGGAGGCCAGATGGCCGCGCAAGTATCAATTGCACGAGCATCACAGGCAGCAGCACACCTGGGAAGAGGCTCCGCATGTCTGCCAGCGGTGCGATTCGCGTTTCCTCAGtctccagctgctggagcATCATACTCTACAGCTCTGCCAGAACACTCTGAAGCGATACATGTGCGACAAGTGCCCGCAGCGCTTCTTTTGGCGAAAAAATCTGCGTGCCCATCTTGTCGAGCACAAGAGCAAGCAAGACAACTATCCGTGCGACCAATGCCAGCGTAGCTTTCAGGATAAAAGCGCCGTGACCAAGCACAAGCTGATGATGCACCGGGAGGAAACGAATCAACTTATTCCCTGCCGCTGGTGCTCACGGACATTCTATCGTCCCGCCCTCTTGCACAAGCATGTCGAACGGCATGGCTTCACCGGCGAAGATTTGCCTCTTGCAGAGACATTACTGGCCGATGCAGCCAAGCCATCGGGCCCAAAGACTGTCCAGTGCAAGATCTGTGATCTGCAGTTTGTAAGCGTTGCAGATCTGCGCCGTCACAATGCTATGCTGGGCCACAGTGAGCGGATTACCGATTACATGATCAGCACCGAGGCTGGCTTCGAGCTGTTATTGGAGGATACAGATGACAGCGAAGACGACACTACGGGGGGCAGATCCTACTCGTGTGATCTCTGTCAGATGACTTTCCGTCGCCGAAGGGAGATGAGCGAGCATCAGTATTCATTGCACGCATTTGACAAGTTGCCGTATGGCTGCGAGCATTGCATTTATAAGACCGTGGATAAGCTCATGCTGGAGCATCATCTGCGCACACAATGCCTGAACAACGAGAAGCCGTTCAGCTGTTCCCGCTGTAGATACAAGTTTATGTGGAAGGAGAATCTGGAGCAGCACTACGCCATTCAGCATTCCAAGCAGCCGCCCACCCAAGAGCAGTCGTCCATGCCCTTAAGAAGAAGGCGACGCTTCAGATATCAATGCCCCCAGTGCTGGCGATCCTTTGTGGTACAGCCCAGCCTCGATAAGCATATAAGGGACATGCATGTGGCCAAGAGGAATCCGGGCAAGAAATACCTGTGCTCCCTCTGTGGCCTGGAGTCGCTGACGCCCAACAAGCTGAACATCCATATGCGTCGCCACAACGGAGAAAAGCCCTTCAAATGCGATCTCTGCGACATGCGCTTCACAGTTCACTACGAGCTGAAGGTCCATCGGCGGAAGCACACGGGCGAGCGGCCCTACCAGTGCACCTTCTGTGACAAGCATTTTGCCCGACCCGACAAACTGAGACGTCATGTCTACATGCACAGTGCTCGTCGCTAG
Protein Sequence: MTRTCRICGDANGRYWIETPVEKYAEKTFNQLLLELTKIELTMVQAEKLPHWLCSSCSQKLESAYDFVLQAKQTHKLWLQQLEDTGQIMSSGGALECLRETPIHLFEIEGVTIKTEALESAVADVGNSSSDPLVRTRIKKRTVFHFSDTEDDQDDVPLRHRRTASQANSLSVKLHKCNLCGKSFRYITNLYRHKKRDHGYPGHSQGESSESYQNTQKSAVAAQETSNLEQNEDNDEDDDNDNYYKCDQCDKTYKHIMVLIKHKQNVHETNQLPIQSGPKRRNRRDVGEAASPASSGKSIQRTRISTDTLVHSLIKAVQLSDEDGNSGTDNYYKCDQCHKSYKYIVSLIKHKHKDHSEADKNWDDEDNQPLASTSARASAASGSGSPTKASRINRRVQGFDLHRCEPNGAKEIQCMICLRKFTKLRELRDHLRSHPTDFNFQAHGEPIERIAEGFFKTAVESTVEGLKSRILHDLRMGAFGRFYSITNEARYEMSLDSSDTDSDGDADVVLRRSYACELCDSPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDSRFLSLQLLEHHTLQLCQNTLKRYMCDKCPQRFFWRKNLRAHLVEHKSKQDNYPCDQCQRSFQDKSAVTKHKLMMHREETNQLIPCRWCSRTFYRPALLHKHVERHGFTGEDLPLAETLLADAAKPSGPKTVQCKICDLQFVSVADLRRHNAMLGHSERITDYMISTEAGFELLLEDTDDSEDDTTGGRSYSCDLCQMTFRRRREMSEHQYSLHAFDKLPYGCEHCIYKTVDKLMLEHHLRTQCLNNEKPFSCSRCRYKFMWKENLEQHYAIQHSKQPPTQEQSSMPLRRRRRFRYQCPQCWRSFVVQPSLDKHIRDMHVAKRNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSARR*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00481028;
80% Identity: -