Basic Information

Insect: Drosophila prostipennis
Gene Symbol: ush
Assembly: GCA_037075205.1
Location: JBAMCJ010006663.1:651890-657838[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0073 0.57 11.0 0.0 1 20 255 274 255 276 0.90

2 9 0.0017 0.13 13.0 0.8 3 23 330 350 328 350 0.98

3 9 0.12 9.5 7.1 2.4 2 21 396 415 396 416 0.92

4 9 0.1 8.1 7.4 1.9 2 20 793 811 792 813 0.93

5 9 0.01 0.78 10.6 0.0 3 21 863 881 861 882 0.91

6 9 0.019 1.5 9.7 0.0 2 23 955 976 954 976 0.98

7 9 0.003 0.24 12.2 1.2 1 23 982 1004 982 1004 0.99

8 9 0.00076 0.06 14.1 0.8 1 23 1058 1081 1058 1081 0.96

9 9 0.46 36 5.3 0.5 2 20 1200 1218 1199 1220 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0073	0.57	11.0	0.0	1	20	255	274	255	276	0.90
2	9	0.0017	0.13	13.0	0.8	3	23	330	350	328	350	0.98
3	9	0.12	9.5	7.1	2.4	2	21	396	415	396	416	0.92
4	9	0.1	8.1	7.4	1.9	2	20	793	811	792	813	0.93
5	9	0.01	0.78	10.6	0.0	3	21	863	881	861	882	0.91
6	9	0.019	1.5	9.7	0.0	2	23	955	976	954	976	0.98
7	9	0.003	0.24	12.2	1.2	1	23	982	1004	982	1004	0.99
8	9	0.00076	0.06	14.1	0.8	1	23	1058	1081	1058	1081	0.96
9	9	0.46	36	5.3	0.5	2	20	1200	1218	1199	1220	0.91

Sequence Information

Coding Sequence: ATGGTGGAGACTTTTGGGAGCTGTGGCCCGCACGAGCAGGCCAAAATGTTCGCTGCGGTCGAGATGTCGAATTTCTGGCGAAGCGAGATGCGAGAtgcaaactgcaaactgcgACGCTTATCCGGCGGCTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACTGTCCACTGTCCACCGTTCACTTCCCCAATTCCAAAGATCTGACCGCCCAGGAAATGGGCGaggagaagcagcagcaaatggAGGATCAGATGGAGGACTCCAGCGACCCCCAAgagaacaacaataataataacaatattaataatgaCGATGATGGAGATGAAGATGGCTCTTTTGAGCAGCCAGAAGAGACTAATCCCGTGGAGGATCAGGATTTGGGGGAGACAGAGATGGAGCAGGATCAGGATGTTCGgcgggaggaggaggcggatcAGCTGGAACTGCCAGCACTGAACAGTCCCAGCACTCCGCCCAGGAGTCCCATCTCCCCCCAGCTGATTCCCAAGCTGGAACAGCCCGCCACGCCGCCCTCGGAGGCGGAACCTTCTCCATGTCCCTCGCCCTGTCCTCCCACGCCCACTCCAAAGTTCCCCAAGGTGCGTCTGAATGCGCTCCTGGCCTCGGATCCTGCCCTCAAGCCCGATGCCAAGGAGCTGACGCTGCCCGACTCCCGTCTCCTGGCTCCGCCGCCACTGGTCAAGCCGGAGGCGCAGGCACCGCCGCCGGAGGAGCCCCATCTCAAGCCAGCCCGGTTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCACCCTCGACGCTGGAAGCCCACCAGGCCTACTACTGCTCTCATCGGATCAAGGAGACGGACGAGGCGGGCAGTGATAAGTCGGGGGCAGGAGGATCTGCAGGAACAGCTGGCGATGGAGGATCCGGCTTAACCGGTGGCTCCGGCTCCGAGCCACCGGCCAAAATGGCCAGAACGGGCAAGCAGTACGGCTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTGTCCCTCAACCGCCACATGCGGATGCACCAGACCTCGCCGGCGGCTCCCACTTTGGCCAGTTTGCCGAGTCTCCTCCAGAACGGAATACCACCGCCGTTACCGGTTGGTAACGTAGCGCAGCCCCTTTCGCTGGAGGACAGCCCTAGTCAACAAACTGATCGCTACTGCAGCCACTGTGATATCCGGTTCAACAACATCAAGACCTATCGGGCGCACAAGCAGCACTACTGTAGTTCCAGGAGGCCGGAGGGTCAACTTACGCCCAAGCCAGATGCCTCCCCGGGCTTGGGAGGATCAGGAGGAGCAAGTGGTTCCACTGGTGGACCCGTTGCGTCCAGTGCGCAGGCAGCTGCTCCCGGCAAGCTGAGTCCGCAGGCCAGGAACAAAACACCCACGCCGGCCATGGTCGCTGTGGCGGCTGCTGCAGCGGCGGCCGCTGCCTCCCTCCAGGCGACGACCCATTCGCACCCGCCCTTCCTGGCGCTGCCCACCCACCCGATCATCATTGTGCCCTGCTCGCTGATCCGAGCGGCCAGCTTCATTCCAGGACCACTGCCCACACCGAACTCGGGGATTGTGAATCCAGAGACCACCTGCTTCACCGTGGACAATGGAACGATCAAGCCCCTGGCCACTGCCCTCATCGGCGCCTCCTTGGAGCCCGAGCGCCCCTCGGCTCCCTCGTCAGCTGCGGAGGCCACCGAACCCAAGAGCAGTCCACCGGAACCCAAGCGAAAGGAGGCAGGAGGAAGTCGcGAATCTGCGCCTTTGGATCTCTCGCTGCGTCGATCGCCCATCTCCCTGAATTCCCTGAGCTTGCGACAGCACCAATTGCGCAACGCCCTTCTCGATGTGGAGGAAGTACTCCTTGCCAGCgccgcaggaggaggaggaggaggaggaggaagtgcTAAGGATCACGTGGAAGCTCCGCGAGGAGGTGGAAGTGTGACTCCCGAGCAGATCGTGTGCGCCCCCTCCCTGCCCTCGAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATCAGTCCACGCAGCTCGGGCGCCGGCAGTGCCTCCTCCATGTCGCCACCTGGCCTCAACGTGGCCGTGCCCCACATGCTCGACATGCGCTCCATGCTGCCGGCGGACTTTGGCCTCTCCGAATCGCTGTTGGCCAAGACCAATCCGGAATTAGCTCTCAAACTGGCGGCGGCAGCTGCGGCGGCTGCTGTGGCGGGCAGTGGAGCTGCTGGAGCGGCAGCCTTTTCCCCATCTCCCCTCGCTTCCTCTTCCGCCCAGACGAGTGGAAATCCCGGAAGCGGGGCGACTCCACAGCAGCCGCAAATCTATGTGAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTTTGCCAGTACGAGAATTACTTGGTCCACAAGCAGCACTACTGCTCGGCGAGGAGTCAggagggaggaggaggagcggcTGGAGGAGATGGGGATGTCAAGTCGTCGGCCGTTTCACCATCCAATCCAGGAGCAGAAGCATCTTCCTCCGTGGAAGCCACTCCGGTGGCCTATCAACAACTGATCTGCGCCGCCTGCGGCATCAAGTACTCTTCGCTGGACAACCTGCGGGCGCACCAGAACTACTACTGCCCCAAgggaggagcagctgcagctgcagtcgCTGCCTCCGCCGCAACGCCCTCGGATCCTGGCCAGCTGGCCATGGTGAAGGAGAAGTGCGGCAAGTGCAAGAGCCTGCATGAGATTGGCCTGCCCTGTCCACCACCCGTCTCGAATCCACTCCACGCAGcagccaccagcagcaacTCCCAACCCGCCGCCACCTCCAACAGCCTGAACAAGTGTCCCGTCTGCGGAGTGATCAGTCCCACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCACGGCACAGTGAAGGCCTATCGCTGCAGCATCTGCCAGTACAAGGGCAACACCCTGCGCGGCATGCGCACCCACATTCGCACGCACTTCGACAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGAGGGCAGCTCGGCTCTGAACCAAGAGCTGCCTACCGCAGCGGGAGCGTCTGCATCTGCAACAGTTGCCCACGATTCCATGGATCATCCCTCTCAGATGTTCAACTGCGACTACTGCAACTATGCCTCCAGCTACAAGGGCAATGTGCTGCGACACATGAAACTGATGCATCCGCACGTGGCCATCAACTCACCTTCAATTTCCCCCGACGCCAGGGAGCAGGAGGTGTCCTCGATCACCACTCCCAACCAGCACTCGAATTCCGATGGTTCCAACGGTGAGGCAGCCAGCTTCCACATCAAATCAGAGCCCCTGGATCCTCCGCCGACGCTGAGTCTGGTgcacgacaacaacaactcgCCGATTCCGACGATTCCCCACATCAAGGCTGAGCCCATGGAGATCGGTGCGGATGCGATGTCGCCCGTTGGTGGGCTGGTTCCGCCGATGGCCTCTCCGCTGGGCAACAGCAGCGTGGCCGCCGCAGCAGCTGCCGCCGTCGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTACGTGAAGACCTACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCGATTCGCCCGGAGGCGAGCGACAGTCCCAGTCCGAATCATCTGGGCGGCGGAGGCGTGGCCGTGGGCCTGGGCATCGGCGGAcatggccagcagaagcagaacaAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MVETFGSCGPHEQAKMFAAVEMSNFWRSEMRDANCKLRRLSGGSICMPCVCHVHVHCPLSTVHFPNSKDLTAQEMGEEKQQQMEDQMEDSSDPQENNNNNNNINNDDDGDEDGSFEQPEETNPVEDQDLGETEMEQDQDVRREEEADQLELPALNSPSTPPRSPISPQLIPKLEQPATPPSEAEPSPCPSPCPPTPTPKFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPEAQAPPPEEPHLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKETDEAGSDKSGAGGSAGTAGDGGSGLTGGSGSEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPSLLQNGIPPPLPVGNVAQPLSLEDSPSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGLGGSGGASGSTGGPVASSAQAAAPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATTHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALIGASLEPERPSAPSSAAEATEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQHQLRNALLDVEEVLLASAAGGGGGGGGSAKDHVEAPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHMLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSGAAGAAAFSPSPLASSSAQTSGNPGSGATPQQPQIYVKKGVSKCMECNIVFCQYENYLVHKQHYCSARSQEGGGGAAGGDGDVKSSAVSPSNPGAEASSSVEATPVAYQQLICAACGIKYSSLDNLRAHQNYYCPKGGAAAAAVAASAATPSDPGQLAMVKEKCGKCKSLHEIGLPCPPPVSNPLHAAATSSNSQPAATSNSLNKCPVCGVISPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEGSSALNQELPTAAGASASATVAHDSMDHPSQMFNCDYCNYASSYKGNVLRHMKLMHPHVAINSPSISPDAREQEVSSITTPNQHSNSDGSNGEAASFHIKSEPLDPPPTLSLVHDNNNSPIPTIPHIKAEPMEIGADAMSPVGGLVPPMASPLGNSSVAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGGVAVGLGIGGHGQQKQNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00537041;
80% Identity: -