Basic Information

Insect: Drosophila lutescens
Gene Symbol: ush
Assembly: GCA_037075285.1
Location: JBAMCF010000324.1:667081-672393[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0074 0.6 11.0 0.0 1 20 277 296 277 298 0.90

2 9 0.0017 0.14 13.0 0.8 3 23 352 372 350 372 0.98

3 9 0.12 9.9 7.1 2.4 2 21 416 435 416 436 0.92

4 9 0.1 8.4 7.3 1.9 2 20 811 829 810 831 0.93

5 9 0.01 0.81 10.5 0.0 3 21 879 897 877 898 0.91

6 9 0.0067 0.54 11.1 0.0 2 23 966 987 965 987 0.98

7 9 0.003 0.24 12.2 1.2 1 23 993 1015 993 1015 0.99

8 9 0.00083 0.067 14.0 0.9 1 23 1069 1092 1069 1092 0.96

9 9 0.46 37 5.3 0.5 2 20 1212 1230 1211 1232 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0074	0.6	11.0	0.0	1	20	277	296	277	298	0.90
2	9	0.0017	0.14	13.0	0.8	3	23	352	372	350	372	0.98
3	9	0.12	9.9	7.1	2.4	2	21	416	435	416	436	0.92
4	9	0.1	8.4	7.3	1.9	2	20	811	829	810	831	0.93
5	9	0.01	0.81	10.5	0.0	3	21	879	897	877	898	0.91
6	9	0.0067	0.54	11.1	0.0	2	23	966	987	965	987	0.98
7	9	0.003	0.24	12.2	1.2	1	23	993	1015	993	1015	0.99
8	9	0.00083	0.067	14.0	0.9	1	23	1069	1092	1069	1092	0.96
9	9	0.46	37	5.3	0.5	2	20	1212	1230	1211	1232	0.91

Sequence Information

Coding Sequence: ATGGGCGGCCGACGGAGGGGGGCGGAGACTTTTGGGAGCTGTGGCCCGCACGAGCAGGGCAAAATGTTCGCTGCGGTCGAGATGTCGAATTTCTGGCGAAGCGAGAtgcaaactgcaaactgcGACGCTTATCCGGCGGCTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACTGTCCACCGTTCACTTCCCCAGTCCGCCGCCATAATCTCGGCCAGCATCGCCGTTGATTCCAAAGATCTGACCGCCCAGGAAATGGGCGaggagaagcagcagcaaatggAGGATCAACTGGAGGATCAGATTGAGGACTCCAGCGACCCCCAAGagaacaacaataataataacaataataataatgacgATGGTGGAGATGAAGATGGTGACTTTGAGCAGCCAGAAGAGACTAACCCCGTTGAGGATCAGGATTTGGGGGAGACAGAGATGGAGCAGGATCAGGCTGTTCGACGGGAGGAGGGGGAGCAGCTGGAGCTGCCTGCACTGAACAGTCCCAGCACTCCGCCCAGGAGTCCCATTTCCCCCCAGCTGATTCCCAAGCTGGAACAGCCCGCCACGCCGCCCTCGGATGCGGAAGCCTCGCCCTGTCCCTCGCCCCGTCCttccactcccactcccactcccacgCTTACGCCCAATTTCCCCAAGGTGCGTCTGAATGCGCTCCTGGCCTCGGATCCTGCCCTCAAGCCAGATGCCAAGGAGCTGACGCTGCCCGACTCCCGACTCCTGGCTCCGCCGCCACTGGTCAAGCCGGAAGCGCAGGCACCGCCGCCGGAGGAACCCCATCTAAAGCCAGCCCGATTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCACCCTCAACGCTGGAAGCCCACCAGGCCTACTACTGCTCTCATAGGATTAAGGAGACGGACGAGGCGGGCAGTGATAAGTCGGGGGCAGGAGGATCTGCAGGAGCCACTGGCGATGGAGGGTCCGGCCTATCCGGTGGCTCCGGCTCCGAGCCACCAGCCAAAATGGCCAGGACGGGAAAGCAATACGGCTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTGTCCCTCAACCGCCACATGCGGATGCACCAGACCTCGCCGGCGGCTCCCACACTGGCCAGTCTGCCAAGTCTCCTCCAGAACGGAATACCACCATCGTTACCAGCCGTAACGCAGCCCCTTTCGCTGGAGGATAGCCCTAGTCAACAAACTGATCGCTACTGCAGCCACTGTGATATCCGGTTCAACAACATCAAGACCTATCGGGCGCACAAGCAGCACTACTGCAGTTCGAGGCGGCCGGAGGGTCAGCTAACCCCCAAGCCGGACGCATCGCCGGGCCTGGGAGGTCCGGGAGGACCAAGTGGTTCCGCTGGACCCGTGGTGTCTGCGCAGGCAGCTGCACCCGGCAAGCTGAGTCCGCAGGCCAGGAACAAAACACCCACGCCGGCAATGGTCGCTGTGgcggctgctgcggcggcggcggccgcCTCCCTCCAGGCCACGACCCATTCGCACCCGCCCTTCCTGGCACTGCCCACTCACCCGATAATCATTGTGCCCTGCTCGCTGATCCGGGCGGCCAGCTTCATTCCAGGACCACTGCCCACACCGAGCTCGGGGATTGTGAATCCAGAGACCACCTGCTTCACCGTGGACAATGGAACGATCAAGCCCCTGGCCACTGCCCTCATTGGCGCCTCCTTGGAGCCCGAACGCCCCTCGGCTCCCTCCTCAGCTGCTGAGACCACGGAACCCAAGAGCAGTCCACCGGAACCCAAGCGAAAGGAGGCGGGAGGAAGTCGcGAGTCTGCGCCCTTGGATCTCTCGCTGCGTCGATCGCCCATCTCCCTGAACTCTCTGAGCTTGCGACAGCACCAATTGCGCAACGCCCTCCTTGATGTGGAGGAAGTACTCCTTGCCGgcgccggaggaggaggaggagcaagtGCTAAGGATCACGCGGAAACTCCGCGAGGAGGCGGAAGTGTGACTCCCGAGCAGATCGTTTGCGCCCCCTCCCTGCCCTCGAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATCAGCCCACGCAGCTCCGGCGCTGGCAGTGCCTCCTCCATGTCGCCACCTGGCCTCAACGTGGCCGTGCCCCACATGCTCGACATGCGCTCCATGCTGCCGGCGGACTTTGGCCTCTCCGAATCGCTGTTGGCCAAGACCAATCCCGAGCTGGCTCTCAAACTggcggcggcagctgcagcggctGCTGTGGCGGGCAGTGGTGCTGCTGGAGCGGCAGCCTTTTCCCCATCTCCTCTCGCTTCCTCTGCCCAGGCGAGTGGAAATCCCGGAAGCGGGGGATCAGTCGGTGGAGGCGCCCAGCAGCCGCAAATCTATGTGAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTTTGCCAATACGAGAATTACTTGGTCCACAAGCAGCACTACTGCTCGGCGAGGAGTCAGGAGGGAGGAGGAGCGGGTGGAGGAGATGGGGATGTCAAGTCGGCCGTTTCCCCATCCAATCCAGGAGCAGAAGCATCTTCGTCCGTGGAAGCCACTCCGGTGGCCTATCAACAACTGATCTGTGCCGCCTGTGGCATCAAGTACTCTTCGCTGGACAACCTGCGGGCGCACCAGAACTACTACTGCCCCAAGGGGGGAGCAGCTGCATCCGCTGCCTCCGCCGCCACGCCCTCGGATCCTGGACAGCTGGCCATGGTGAAGGAGAAGTGCGGAAAGTGCAAGAGCCTGCATGAGATTGGCCTTCCCTGTCCGCCGCCCGTCACCAATCCACTCGCAGCACCCACCAGCAACTCCCAGCCCGCCGCCTCAAATAGCCTGAACAAGTGTCCCGTCTGCGGAGTGGTCAGTCCTACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCACGGCACGGTGAAGGCCTATCGGTGCAGCATCTGCCAGTACAAGGGCAACACCCTGCGCGGCATGCGCACCCACATTCGCACGCACTTCGACAAGAAGACCAGCGACGTGAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGAGGGCAGTTCCACGCTCAGCCAGGAGCTGCCTCCAGCAGCGGGAGCATCTGCGTCGGCAACGGTGGCCCACGATTCCATGGATCATCCCTCTCAGATGTTCAACTGCGACTACTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTGCGACACATGAAGCTGATGCATCCGCATGTGGCCATCAACTCACCTTCGATTTCCCCCGACGCCAGGGATCAGGAGGTGTCCTCGATCACCACTCCCAACCAGCACTCGAATTCCGATGGTTCTAACGGTGAGGCAGCCAGCTTCCACATCAAGTCGGAGCCCCTGGAGCCCCCGCCGACGCTGAGTCTGGTgcacgacaacaacaactcgCCGATTCCGACGATTCCCCACATCAAGGCTGAGCCCATGGAGATCGGTGCGGATGTGACGTCGCCCGGCAGTGGAGGGCTGGTTCCGCCGATGGCTTCTCCGCTGGGCAACAGCAGCGtggccgccgcagcagcagccgccgtTGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTACGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCGATTCGCCCGGAGGCGAGTGACAGTCCCAGTCCGAATCACCTGGGCGGAGGAGGCGTGGCCGTGGGCCTGGGCATCGGCGGCATTGTGGGTGGACatggccagcagaagcagaacaAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MGGRRRGAETFGSCGPHEQGKMFAAVEMSNFWRSEMQTANCDAYPAAPSACHVCAMSTSTVHRSLPQSAAIISASIAVDSKDLTAQEMGEEKQQQMEDQLEDQIEDSSDPQENNNNNNNNNNDDGGDEDGDFEQPEETNPVEDQDLGETEMEQDQAVRREEGEQLELPALNSPSTPPRSPISPQLIPKLEQPATPPSDAEASPCPSPRPSTPTPTPTLTPNFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPEAQAPPPEEPHLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKETDEAGSDKSGAGGSAGATGDGGSGLSGGSGSEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPSLLQNGIPPSLPAVTQPLSLEDSPSQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGLGGPGGPSGSAGPVVSAQAAAPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATTHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPSSGIVNPETTCFTVDNGTIKPLATALIGASLEPERPSAPSSAAETTEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLSLRQHQLRNALLDVEEVLLAGAGGGGGASAKDHAETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHMLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSGAAGAAAFSPSPLASSAQASGNPGSGGSVGGGAQQPQIYVKKGVSKCMECNIVFCQYENYLVHKQHYCSARSQEGGGAGGGDGDVKSAVSPSNPGAEASSSVEATPVAYQQLICAACGIKYSSLDNLRAHQNYYCPKGGAAASAASAATPSDPGQLAMVKEKCGKCKSLHEIGLPCPPPVTNPLAAPTSNSQPAASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEGSSTLSQELPPAAGASASATVAHDSMDHPSQMFNCDYCNYASTYKGNVLRHMKLMHPHVAINSPSISPDARDQEVSSITTPNQHSNSDGSNGEAASFHIKSEPLEPPPTLSLVHDNNNSPIPTIPHIKAEPMEIGADVTSPGSGGLVPPMASPLGNSSVAAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGGVAVGLGIGGIVGGHGQQKQNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00578840; iTF_00548350;
80% Identity: -