Basic Information

Insect: Drosophila prostipennis
Gene Symbol: prg
Assembly: GCA_037075205.1
Location: JBAMCJ010004477.1:1407625-1409379[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.019 1.5 9.7 0.8 1 23 208 231 208 231 0.95

2 9 0.054 4.2 8.3 0.7 1 23 237 260 237 260 0.96

3 9 3.8e-06 0.0003 21.3 1.6 1 23 266 288 266 288 0.98

4 9 5.4e-09 4.2e-07 30.3 2.5 1 23 294 316 294 316 0.99

5 9 0.00012 0.0093 16.6 0.5 1 23 322 344 322 344 0.98

6 9 1.2e-06 9.7e-05 22.9 0.8 1 23 350 372 350 372 0.98

7 9 8.9e-05 0.007 17.0 1.3 1 23 420 442 420 442 0.96

8 9 0.0003 0.023 15.4 1.5 1 23 447 470 447 470 0.91

9 9 0.16 13 6.7 2.0 1 23 474 496 474 496 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.019	1.5	9.7	0.8	1	23	208	231	208	231	0.95
2	9	0.054	4.2	8.3	0.7	1	23	237	260	237	260	0.96
3	9	3.8e-06	0.0003	21.3	1.6	1	23	266	288	266	288	0.98
4	9	5.4e-09	4.2e-07	30.3	2.5	1	23	294	316	294	316	0.99
5	9	0.00012	0.0093	16.6	0.5	1	23	322	344	322	344	0.98
6	9	1.2e-06	9.7e-05	22.9	0.8	1	23	350	372	350	372	0.98
7	9	8.9e-05	0.007	17.0	1.3	1	23	420	442	420	442	0.96
8	9	0.0003	0.023	15.4	1.5	1	23	447	470	447	470	0.91
9	9	0.16	13	6.7	2.0	1	23	474	496	474	496	0.98

Sequence Information

Coding Sequence: ATGCATATACCGGAGTCCGACGTCACCCAGGATCGGGATGTGAACACCTGCCGCCTGTGCCACCGTGTAACGGATGCCAATTCGCCCAATATTTTCGAGAGCTCGGTGGCGTGCTGCAAAGATGTGTCCATCTCGGAGGTTTCCCAGGCTCTGTGGAGCGTTCAGTACGATCGCCATGAGTTGCTGTCTGAGCTCATTTGCCCGGAGTGTCTGGAGATCCTGGAGGATGCCTTTGAGCAGCGGAGAGGAATGCAGGAGCGGGAGCAGGCGCTGCAGGAGCAGCTTAAGGACGTGATCAGGGAGGATGCCAAGTACCGGCCTGGCTTAAATGGCAACCCAGGCGAATTTACGCCCGAGGAGGGATGCATCATCGTGGACGTAGACCCTGAAAAGCTGGCGGAGACTAGTGAGGATGAGTTTGCCCTGGGTTCCGACGGAGAATATGAAAACTACGAGGACGAcgatgaggacgaggaggaaGACTATgatgaggaggacgaggaagaTGGCCAGAATGGAGAGGATGTGGAAATGCCGCTGGGCATGGATGCGGCCCAGATGGCGGCTCAAAAGACCGTTGCGGCCGACGCCAACTCCGCGACGGCACGGCCAAAGCGCGCTTTCCTTTGCCAGTACTGCGATCTGGGATTCACCCTCCCCTCCGACTGTCAAGAGCACGAGCGGACCGCCCACGATCCTAACGCACCGTTCTGCTGCGCCTACTGCAACCTCAGAATGGTCACCCGGCCCGCTTTGATTTCGCACATCAAGTCACTTCACGATCCGGATCGTCCGTATGTTTGCGCCCACTGCCGTAAAGGATTCGTGCGTCGCTCCGATCTGAAGAAGCACACAATTGTGCACACGGGCGTGCGACCCTATACCTGCAACGTGTGCTCCAAGAGCTTCTCGAGGAACACCAATCTGACCAAGCACATGCGCATCCACAGCGGCGTCAAGCCGTTCGTCTGCCAGCAGTGCCCGCGATCGTTCCAGACGGCAGTGGAAATGATGAGGCATTCGCGATCTCACGGTGAGGTGAAGGCTTTTCAATGTGGCCGCTGTCCTTACTCGTTCTCGCGCAAGGATAAATTGATGGCCCACCAGCAAGTCCACACCAGGCGAGAcgtggagcagcagcagcagcaaatggGACTACTTCCTCCGCTGGAGGGCGATCTGGCgcatctgcagcagcagcaacaggcgtTCCAGGCGAAGCAAAAAGCTCAGACACAGTCTAAAAACTCTCGCAATCACCGATGCGATGTTTGCGATCGTGGCTTCCAGCGCGAGCGGGACCTGCAACGCCATCGAGCACTGCACATGGACTCGCTGTTCGCCTGCAAGACATGTAACCAAGGTTTCAACCGACGCGAGCAACTGCATCGCCATGAACTGGAGGCCCATGGACCCAGCTTTACGTGTGGCATCTGCTGCATCAGCTTCCTCCATCAGATTGATCTCGAGAATCACCTGAAGGTTCATCAGTTGCAGCACAAAATGGCGCAGCGGGCGCAGGAGGCTTCTATTTTGCCCCTCAAAATGGCCGAGCAGGCGCCAGTGGCTATGATGGCTCCGTTGGTCCAGGAACAACCGCCACCAATGCGACCCTCGGCCGCTGAACTCTCGTTCTACAGCAACATGATCCCCACTATGAATCTGGGCTTCTACAGCGAGACTCGACCCGAGGAGTAG
Protein Sequence: MHIPESDVTQDRDVNTCRLCHRVTDANSPNIFESSVACCKDVSISEVSQALWSVQYDRHELLSELICPECLEILEDAFEQRRGMQEREQALQEQLKDVIREDAKYRPGLNGNPGEFTPEEGCIIVDVDPEKLAETSEDEFALGSDGEYENYEDDDEDEEEDYDEEDEEDGQNGEDVEMPLGMDAAQMAAQKTVAADANSATARPKRAFLCQYCDLGFTLPSDCQEHERTAHDPNAPFCCAYCNLRMVTRPALISHIKSLHDPDRPYVCAHCRKGFVRRSDLKKHTIVHTGVRPYTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEMMRHSRSHGEVKAFQCGRCPYSFSRKDKLMAHQQVHTRRDVEQQQQQMGLLPPLEGDLAHLQQQQQAFQAKQKAQTQSKNSRNHRCDVCDRGFQRERDLQRHRALHMDSLFACKTCNQGFNRREQLHRHELEAHGPSFTCGICCISFLHQIDLENHLKVHQLQHKMAQRAQEASILPLKMAEQAPVAMMAPLVQEQPPPMRPSAAELSFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605037;
90% Identity: iTF_00605764;
80% Identity: -