Basic Information

Insect: Drosophila prosaltans
Gene Symbol: zfh1
Assembly: GCA_018151275.1
Location: JAECWY010000500.1:2243288-2247534[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.4e-05 0.0029 18.2 1.4 1 23 147 169 147 169 0.97

2 15 0.00078 0.068 13.9 1.2 3 23 177 197 175 197 0.94

3 15 8.6e-05 0.0075 16.9 0.1 1 23 351 373 351 373 0.98

4 15 0.00051 0.044 14.4 0.8 1 23 379 401 379 401 0.98

5 15 8.3e-05 0.0072 16.9 2.1 1 23 433 456 433 456 0.94

6 15 0.00057 0.05 14.3 1.9 1 23 485 507 485 507 0.95

7 15 0.011 0.95 10.3 1.6 1 23 513 536 513 536 0.97

8 15 0.025 2.2 9.1 0.4 3 19 545 561 544 562 0.95

9 15 0.00015 0.013 16.1 5.6 1 23 571 593 571 593 0.97

10 15 0.045 3.9 8.3 0.4 2 23 599 620 598 620 0.96

11 15 8.8e-06 0.00077 20.0 1.0 1 23 629 651 629 651 0.98

12 15 0.001 0.087 13.5 0.1 3 23 659 679 657 679 0.97

13 15 5.3e-05 0.0046 17.5 0.5 1 23 685 707 685 708 0.95

14 15 0.14 12 6.7 0.2 1 23 718 740 718 740 0.97

15 15 0.0053 0.46 11.2 0.2 1 23 1299 1321 1299 1321 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.4e-05	0.0029	18.2	1.4	1	23	147	169	147	169	0.97
2	15	0.00078	0.068	13.9	1.2	3	23	177	197	175	197	0.94
3	15	8.6e-05	0.0075	16.9	0.1	1	23	351	373	351	373	0.98
4	15	0.00051	0.044	14.4	0.8	1	23	379	401	379	401	0.98
5	15	8.3e-05	0.0072	16.9	2.1	1	23	433	456	433	456	0.94
6	15	0.00057	0.05	14.3	1.9	1	23	485	507	485	507	0.95
7	15	0.011	0.95	10.3	1.6	1	23	513	536	513	536	0.97
8	15	0.025	2.2	9.1	0.4	3	19	545	561	544	562	0.95
9	15	0.00015	0.013	16.1	5.6	1	23	571	593	571	593	0.97
10	15	0.045	3.9	8.3	0.4	2	23	599	620	598	620	0.96
11	15	8.8e-06	0.00077	20.0	1.0	1	23	629	651	629	651	0.98
12	15	0.001	0.087	13.5	0.1	3	23	659	679	657	679	0.97
13	15	5.3e-05	0.0046	17.5	0.5	1	23	685	707	685	708	0.95
14	15	0.14	12	6.7	0.2	1	23	718	740	718	740	0.97
15	15	0.0053	0.46	11.2	0.2	1	23	1299	1321	1299	1321	0.97

Sequence Information

Coding Sequence: ATGAACAATTCGAGTTATGGTACCATCCAATGGATACAACACCACGCCTCCGCTGACGACACAGAGGCGGTCACAATAGACGATGGCGGCGATGCTTATCTGGTTAATGGCACTGCCACAGATGAGGATCTCGATCATATGGCGGCAGAGAATCTAATTTTTATGGCGCGCGATGGTCAGCTGGATGGGATTATAGCTGGAAGTGATGCGGAATCAGGTGGTGCGGTGCTAGTCACGGCCGATGGCACAACGTTAGCCTATGCCGACAAATCTTTTGATGATGAAGCCGAGGTGGTCACTGAGGAGGTCATCACCGATGATTGGGTGCAACATCAAGGAGCTGAGCGGGTGGAAATTGCTGCAGAGCAAATAGCTGGTACTACAAGTTCCCAGGAGCTGTTGGATATGGAGCAGGATGAGTATACGGTACTCCGTCCATATCCCTGTGATTTCTGCAGTCGCCGCTTTCGCAAGAAGGTCAGCCTCAACAATCACATGCAGGCCCATCAAAATGATCGTCCGCATCTCTGCAAGCTGTGCGGTGCCAGATTCTCACGCCGTGGAGAACTGATAAGTCATTTTAAGGCCCATGCCGAGGCCCAGGATGCAGCTGATGCCGAAGCAGCGGCAGCCGCAGCAGCTTCAACTGTAAAATACGAACATCAACAACAACAGCGACAGCTGGATGATCATTACTATGAGCAGGATTGGCCTTTGTATCAGCAAGATCATAATCCGGAGCAAAGCCAGGAGCAGCAATGCCTAATTGTATCCACCAGTGAGGTGCCTCCACTGATGCCACAAACAAACTATCTGACCGAAACCAACGTGGTAAATGCCACACCGGTGGCATCTCGTGGCAGGATTAGTCGACTAAAGCCCAAAGAGGAAGCAACTCAGTATATTGTGATAACCGAAAATGTGCAGAGTGAACCAACCCAGGCGGTGATGACGACATCCACTTTAGTTGATCCTCCACCAGCCGTTGTAACTGCCAATGATCCTCCACAACAGCTTCTCAATTTCCCAGTGCTGGATGAGGGCAAACCATTTGTGTGCCAGCAATGCGGTTTGGCATTTGCTCGAGAAAAGGCTCTGGTGTCTCACATTAAGAACCATCGCGTGGACTCGCCTTTTGAGTGTAACCAATGTCAGGAGATGTTCTGGGACAATACGAGCCTCCAGGAGCACCAGAAAACGCATCAATTCGAGGAGAGTAATTCGGAATACGATCCTGCTTCGGCCTCAGATAGTGGCAGCGAAACAGAACCGGAGGAGCAACAAATTTATGGTGAATTCTATTGTAGCGAATGCGGCATTTCCTTTCACAGACAGAACCTATTGCGTCGGCATGCCAAGGAGCAGCACTTTAAGTCTACAAATGGAACCTATCAACCAGCGAGCATTCAACAAGAAGCTGTCGGCAATCAGGAAAATGGCACAGATGCCCCGCACTGTTGCCATACGTGTGGTAAATCCTTTCCCAGCGCCCTCGAGTTGCTTGCCCATGCTGAGATTCATGCCCGTTTCCCGCCCTTTAAGTGTGTCCTGTGTGGGATGAGCTTCTATGAGGAGCAAGCCATCAAGCGACACTTGCATACCCGCCATCCCCACGAATTGAAGCCCAACTCTTGTGTGTTGTGCGGCAAGGAGTGCCGCGATAGAAAGGCACTTATCAAACATGCCTGGGACCATTCGCGTGAGAAGTGCCACTCTTGCTCCAAATGCGGCAAAAACTTCCATAATAAGGCGCGGCTGAAGCGCCACATGGCATCGCACAGGGACAAGTCGGTGGTTTGTGAAGTGTGCCAAGAAGAGTTTCCCGATGGACGTACATTATCGAATCATCGGCACTCGCACAGCACCACTTCGCCGGGAAAACTTTTTCCCTGCCATGAGTGTGGAAAAACCTTTGGCTCACGCAGCTCTCAGCAGATTCATGTGCGCATTCATACCGGAGAACGGCCATATGGATGTCGCTATTGCTGGAAAGCCTTTGCCGATGGCGGAACACTTCGTAAACATGAACGCATTCACACAGGCGAGAAGCCCTATGCCTGCTCGGTCTGTCCACGTGCCTTTAATCAGCGTGTCGTTCTCCGTGAACATATACGCTCCCATCACTCGGGTTTGGATGTAACAAAGGGAACTTACCATTGTACTGTCTGCACGGCAGACTTACCATCATCCAACGAGCTTATCCAGCATCTCATTCAGCATAGTGACTCAAATACAGCCAAGCAGAGGCAACCAATTACTGGTCCGCGAAAGTACAAGCGACGCCGTAAGCTTCAGCCCCATGAAATAGCACAGTTGCGTGATGAACATCAGGATGTTGAAACTGCCGGTGATGACGGTTTGGTTGAGGATGAGGTTGACGGTGACGGTTATGCCACCGACATTGACATCTGCGATTTCGATATGGAAAATGTAGATGATATCTTTGAAATGGCATCCTCGACCCATACCAACAAAAAGGAAAGGCGCAAAAAGTCGTCGGCAAAGGACACCAAGCCACCAAAGAATGGGGCAGTGTCCAAGCCAGAAGCTGGATTGGTTCAGCATAAATCTAAACAGCGCTATGATTCCAATAGTAGTCAATCGGAACGTATGTGGGGTGATAAACAGGATAATCAAGTGGCCTTCTTTCAAATCGATTCTCTGGTGGTGGTTAATGACACTACACTGGAGCCAGCTAGTTCAGTGAGCTGTCCCAATGGTAACACGACTAGGACACGAGGACGCTCTGTTAAACAATCGGCACAGATGCAACCAAAAGTGCCTCCTCCTATTGATAGTAAAACCGATTTCATTGCCACTTCTTACGCTTCATCCGGTGGCTCTAGTAGTCGTGGTAAAAAGAAGACTGCCACCAAGCCAAGTGCAGCCAGCGTCTCGCGTCCACGTATGATTCACACTGAAAAGACCAAGGTTTCTCGACCGGCTACAGAAAGTACAAGCGCTGGAGCAGGAGGGGGCAAAAGAACTCGTTCCAAAACTTATATAACTCGCACAGAGACCAGCAATTTGGATTTGCTATCAAGCGGCAATGGGAAGACAAACACCACAGCAGCGACTGCATCCAATATGGTGGACGATTATGAGATCATTTCCCCTGCCACACAGCCACCTAATCAGATAAGTTCCAGTCCCTTGCACATAAAACAGGAGCAGGAACAACAGCGTGTCCAATTGATGTACGATGATACTCTCCTTATCGATGCAGCACTTTTGCGTGAGAAGACTTACGAGAAGTTCAATCCGAGCATTGTCAATGATTTGGAGGAGATTCTGCGATCGCCATTGAAAAGTGATAGAAATTCAAGTCGCCTGCGTTTCACCAGTGAATCCTCAACAACACCACAGTTCCTGCCCAGTGAAGAGCAAAACCTCATTAAAATCGAGCCCACTTCGCCGGATTTGCGGGAAATGGTAGAGGGCCAACAGCGAATTACGAATTGTATTGCCACGCCATCCTCCATTGCATCCTCCTCGTCACCGTCAACTACAAGTAATTCGCGTCATTTGCGTCAACTTACTGCCAATAGTCAGCGGGCGGGTAGCAAACGATCCGCTGGCAGCTCTATCAGCACAAGTACCAATAAATCTGCCTCAACAACTTCCACGAGCTCTGTGACAAAAAAACCAGCTTTATCTTCCACTACCTCCCCCTCGGTGGGGGTTGGTAAAGTCACTAGGAACACTGTCAGCAACTCTTACCTTAGCTACGGAGTAGGCGTAGATGCCTATAATGTGAATGTACCTGCCAATGGCAGCGCCTCCGATGTGAGTTCCGGTTACTTCTCCATCTCCGAGGTTGTCTCCGCCGCAGAAACAGCCGATGCAGCAGCCAAAGAGGCGGCGGCCGGCAAATCGGAGCGCAAGACGCGCAGCTTTGAATGTGAAATGTGTTCGGCTATATTCTATGATCGCGCCCAGTTATTGGAACATGTTCATATACACATTTAA
Protein Sequence: MNNSSYGTIQWIQHHASADDTEAVTIDDGGDAYLVNGTATDEDLDHMAAENLIFMARDGQLDGIIAGSDAESGGAVLVTADGTTLAYADKSFDDEAEVVTEEVITDDWVQHQGAERVEIAAEQIAGTTSSQELLDMEQDEYTVLRPYPCDFCSRRFRKKVSLNNHMQAHQNDRPHLCKLCGARFSRRGELISHFKAHAEAQDAADAEAAAAAAASTVKYEHQQQQRQLDDHYYEQDWPLYQQDHNPEQSQEQQCLIVSTSEVPPLMPQTNYLTETNVVNATPVASRGRISRLKPKEEATQYIVITENVQSEPTQAVMTTSTLVDPPPAVVTANDPPQQLLNFPVLDEGKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNTSLQEHQKTHQFEESNSEYDPASASDSGSETEPEEQQIYGEFYCSECGISFHRQNLLRRHAKEQHFKSTNGTYQPASIQQEAVGNQENGTDAPHCCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGMSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVTKGTYHCTVCTADLPSSNELIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAQLRDEHQDVETAGDDGLVEDEVDGDGYATDIDICDFDMENVDDIFEMASSTHTNKKERRKKSSAKDTKPPKNGAVSKPEAGLVQHKSKQRYDSNSSQSERMWGDKQDNQVAFFQIDSLVVVNDTTLEPASSVSCPNGNTTRTRGRSVKQSAQMQPKVPPPIDSKTDFIATSYASSGGSSSRGKKKTATKPSAASVSRPRMIHTEKTKVSRPATESTSAGAGGGKRTRSKTYITRTETSNLDLLSSGNGKTNTTAATASNMVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQLMYDDTLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKSDRNSSRLRFTSESSTTPQFLPSEEQNLIKIEPTSPDLREMVEGQQRITNCIATPSSIASSSSPSTTSNSRHLRQLTANSQRAGSKRSAGSSISTSTNKSASTTSTSSVTKKPALSSTTSPSVGVGKVTRNTVSNSYLSYGVGVDAYNVNVPANGSASDVSSGYFSISEVVSAAETADAAAKEAAAGKSERKTRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501217;
90% Identity: iTF_00591119;
80% Identity: -