Basic Information

Insect: Drosophila planitibia
Gene Symbol: RREB1
Assembly: GCA_035043785.1
Location: JAWNMS010000048.1:2812262-2819195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.037 2.3 8.7 0.8 1 21 275 295 275 297 0.93

2 13 0.00035 0.021 15.1 0.2 1 23 307 329 307 329 0.98

3 13 0.00026 0.016 15.5 7.2 1 23 335 357 335 357 0.98

4 13 0.24 15 6.1 1.7 2 20 589 607 589 609 0.93

5 13 0.016 1 9.8 0.2 1 23 756 778 756 778 0.97

6 13 1.3e-05 0.00079 19.6 0.7 1 23 788 810 788 810 0.99

7 13 0.00086 0.053 13.9 2.0 1 23 816 839 816 839 0.97

8 13 0.0031 0.19 12.1 2.0 1 23 1122 1145 1122 1145 0.95

9 13 8.9e-05 0.0055 17.0 0.3 2 23 1538 1559 1537 1559 0.97

10 13 0.15 9.3 6.8 6.3 1 23 1565 1588 1565 1588 0.97

11 13 9.7 6e+02 1.1 3.4 1 23 1705 1728 1705 1728 0.78

12 13 0.0087 0.54 10.7 0.5 3 23 1789 1809 1787 1809 0.96

13 13 0.0014 0.086 13.2 4.8 1 23 1815 1837 1815 1837 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.037	2.3	8.7	0.8	1	21	275	295	275	297	0.93
2	13	0.00035	0.021	15.1	0.2	1	23	307	329	307	329	0.98
3	13	0.00026	0.016	15.5	7.2	1	23	335	357	335	357	0.98
4	13	0.24	15	6.1	1.7	2	20	589	607	589	609	0.93
5	13	0.016	1	9.8	0.2	1	23	756	778	756	778	0.97
6	13	1.3e-05	0.00079	19.6	0.7	1	23	788	810	788	810	0.99
7	13	0.00086	0.053	13.9	2.0	1	23	816	839	816	839	0.97
8	13	0.0031	0.19	12.1	2.0	1	23	1122	1145	1122	1145	0.95
9	13	8.9e-05	0.0055	17.0	0.3	2	23	1538	1559	1537	1559	0.97
10	13	0.15	9.3	6.8	6.3	1	23	1565	1588	1565	1588	0.97
11	13	9.7	6e+02	1.1	3.4	1	23	1705	1728	1705	1728	0.78
12	13	0.0087	0.54	10.7	0.5	3	23	1789	1809	1787	1809	0.96
13	13	0.0014	0.086	13.2	4.8	1	23	1815	1837	1815	1837	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcagcaacagcagcagcagcaacaacaacagcaacaatcgcaCACAGcatctgcaactgcagcagcagcagcagcagcagcagcagtagcagcaacacaTGAAGATGCTCGGGATTTGGAGTTAATGGAGACGCGACAGCGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGacagcaacaccaccagcagcagcagcagcaacagtcgccgCTCTCCGatgaggagcaacagcagcaacaacagcagcagctgttggacTCATCAGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCgccgttgctgccgctgccagcgCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAATCGGGTTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTgcttggcagcaacaacaacaacaacaacaataataataacaacaacaacaatatcagtaatagtagcagcagcagcagcgcagtcgctcagtcagcagcagcagcgtcggcAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCTGAGTCGGGCATCGGTGCCGGCGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTAAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcaacagcagcagcagcactcgcaacagcagcaatccacacaacagcagcaacaggcacagtcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCGggtggagcaggagcaactgGCTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaataacaacaacaacaatagccacaaaacgaacaacaataacaataacaacaacaacaacaatgaggaTGAGCTCGAGCTGGAGGATGAGCAGCTAGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGCcctgaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGACAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCTTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTCACCgcccctgctgctgcagagctGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGTGAACTGGaggagcagcaccagcagcagcacgaggaggaggataacgaacagcagcagcacaagcaggaggaacaggagcaggctGAGCAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAACAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGACCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGGCGAATGAAACTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGTGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCCGCGCTCGTCCGGCACATGCGCACCCACAACGGCGATCGGCCTTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGTCACTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTTTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAAGCCGATATCCTAACGGAGCTGGGCGGCTATCGTTGTGCAACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGTAAaggtagcagcaacaacagctgcagtagcagcagcagcagcagcagcaacaacaacatcgctGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCAGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACACGAATtggtgctgcagcagcaacagcagcagcaacaacaacagctgcagcagcagcagcaacagcagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTAtatgcaacagctgttgcGCAACTTCATGCTCCAGCAATCACCCGGTTTTCCCTTCTTTGCGTTTATggcgccaccgccaccaacagcggcagcagcagcagcagcagcaacagcagcagacaaatcaatgacaacaaatccagcagcagcagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCTGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTCCGCTCCAACATGGAGCGCCATgtaaagcagcagcatccacagtTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCCTCGAGTGCTGTCCAAGCGGCAGCCGCtgcacaggcagcagcagcagccgccgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcactCGCATTCACATCACGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttgGCGCAGCAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATttcagctacaacaacaacaacagcagcaacagcatcagcaacaagcagcagcaacaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCgaggacgatgaggatgaggaggaggagcaggaatttgatgttgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGatgagcatcagcagcagctgcacgacgaggatgatgatgatgatattgatgatgatgatgatgcagcagcaacagcaacagcagcaacagcagcagcagctgcagctgcagcagaggcgtcgcagcaacaattgcagccaaCCAAGGACAAGCTGCAAGCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCGGCCGAGAAGCAGCCGCATCCTCAATCGGAGTCCGTGGGCGGCAATAAGCCGGcggcgccaacaacaatgaaaacgaTGATTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCTAGCGACGTTGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCACTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACACCAGTTGCGCCAACAAATGgccgctgcagcggctgctgtcgctgttgccgcCGTTGCTACACCAACGCATCCACCACCGCCGGCCCAATCGCCGCCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCgcactgctgctggccaagggGGCCATCGAAACGGATGCACagctccagcaccagcagcagcagcaacaattgccagcGGCTGGTGGTGCTCCACATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGACGATGAGCAGCTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaacaacaataacaataacaacaacaatagcaatggcaAGCAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGCGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagcagcagctgttgccagtGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQQQQQSHTASATAAAAAAAAAVAATHEDARDLELMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHQQQQQQQSPLSDEEQQQQQQQQLLDSSAQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNNNNNNNNNNNNNNISNSSSSSSAVAQSAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQSQQQQQRRQQHAGGAGATGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNNSHKTNNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQHEEEDNEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELGGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTAAVAAAAAAATTTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELVLQQQQQQQQQQLQQQQQQQQQQQMFGAGDAAAQYMQQLLRNFMLQQSPGFPFFAFMAPPPPTAAAAAAAATAADKSMTTNPAAAAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAAMSNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNSSNSISNKQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQLHDEDDDDDIDDDDDAAATATAATAAAAAAAAEASQQQLQPTKDKLQAKPIEAAKKVAETILEQAIKEREEKAAEKQPHPQSESVGGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIHQLRQQMAAAAAAVAVAAVATPTHPPPPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQLPAAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNNNNSNGKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -