Basic Information

Insect: Drosophila picticornis
Gene Symbol: RREB1
Assembly: GCA_035043845.1
Location: JAWNMR010000492.1:3490899-3497569[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.038 2.3 8.7 0.8 1 21 267 287 267 289 0.93

2 13 0.00035 0.022 15.1 0.2 1 23 299 321 299 321 0.98

3 13 0.00026 0.016 15.5 7.2 1 23 327 349 327 349 0.98

4 13 0.25 15 6.2 1.7 2 20 581 599 581 601 0.93

5 13 0.016 1 9.8 0.2 1 23 749 771 749 771 0.97

6 13 1.3e-05 0.0008 19.6 0.7 1 23 781 803 781 803 0.99

7 13 0.00087 0.054 13.9 2.0 1 23 809 832 809 832 0.97

8 13 0.0031 0.19 12.1 2.0 1 23 1109 1132 1109 1132 0.95

9 13 9e-05 0.0056 17.0 0.3 2 23 1526 1547 1525 1547 0.97

10 13 0.15 9.4 6.8 6.3 1 23 1553 1576 1553 1576 0.97

11 13 9.8 6.1e+02 1.1 3.4 1 23 1694 1717 1694 1717 0.78

12 13 0.0088 0.54 10.7 0.5 3 23 1779 1799 1777 1799 0.96

13 13 0.0014 0.086 13.2 4.8 1 23 1805 1827 1805 1827 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.038	2.3	8.7	0.8	1	21	267	287	267	289	0.93
2	13	0.00035	0.022	15.1	0.2	1	23	299	321	299	321	0.98
3	13	0.00026	0.016	15.5	7.2	1	23	327	349	327	349	0.98
4	13	0.25	15	6.2	1.7	2	20	581	599	581	601	0.93
5	13	0.016	1	9.8	0.2	1	23	749	771	749	771	0.97
6	13	1.3e-05	0.0008	19.6	0.7	1	23	781	803	781	803	0.99
7	13	0.00087	0.054	13.9	2.0	1	23	809	832	809	832	0.97
8	13	0.0031	0.19	12.1	2.0	1	23	1109	1132	1109	1132	0.95
9	13	9e-05	0.0056	17.0	0.3	2	23	1526	1547	1525	1547	0.97
10	13	0.15	9.4	6.8	6.3	1	23	1553	1576	1553	1576	0.97
11	13	9.8	6.1e+02	1.1	3.4	1	23	1694	1717	1694	1717	0.78
12	13	0.0088	0.54	10.7	0.5	3	23	1779	1799	1777	1799	0.96
13	13	0.0014	0.086	13.2	4.8	1	23	1805	1827	1805	1827	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcagcagcagcagcagcagcaacaacaacagcaacaatcgcacacagcatcagcaactgcagaagcagcagcaacacacgAAGATGCTCGGGATTTGGGGTTAACGGAGACGCGACAGCGTCGTGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAAAAgttgaccagcagcagcggtgcGCCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAACGCAAGCTGCGacagcaacaccaccagcagcagcagcagttgccactCTCCGatgaggagcaacagcaacagcagcagcagctgttggatTCATCAGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCGGCGTTACTGGCGCTGCCAGCGCTAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTTCGAAAAAAGTTTCGACTGAATCgtagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAATCGGGCTTCGTTGACGGCAGCGCCCTCAGTGGTTATCTgcttggcagcaacaacaacaacaacaataataataacaacaacaacaacaacaatatcagtaatagtagcagcagcagtgcagtcgctcagtcagcagcagcagcagcagcgtcggcAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACTACCAATGGAAATATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcagcaacagcagcagcactcgcaacagcagcaatccacacaacagcagcaacaggcacagtcgcagtcgcagcaacaacagcaacgacgcCAGCAACATGCAGGTGGAGCAGGCGCAACTGGTTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCCACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaataacaatagccacaaaacgaacaacaacaataacaacaacaacaacaacaatgaggaTGAGCTCGAGCTGGAGGATGAGCAGCTCGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGCTGATTCGGACGCGGACAGCGCCGATAGTGTCGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTACTCGCCTCGGGCGACACCTCGCCCACCCACTCGCATTCGGACTCGCACTCAccgcctctgctgctgcagagctGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCAGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAaatggaggaggagcagcaacagcagcagcagcacgaggAAGACcccgaacagcagcagcacaagcaggaGGAACAGGAGCATGCTGAGCAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCATCCGCAACGCTGCTTCCCTCGCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCGAGCTGCACCTCGAGTTTCTTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAAGATGCCTTCACCAATGAATTCAGGCGAATGAAACTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCCTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGACATTTGCGCAATCGACATGGGAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGTCAGCTGCGAGGAGAACAAATCGCGGACCGAAGCCGATATCCTAACGGAGCTGAGCGGGTATCGTTGTGTAACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAGCTTAAGCACATGTTGCTGGCAGAGCCGACGCCGGCCGTAAaggtagcagcaacaacagttgcagcagcagcagcaacaccatcGCTGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCAGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGAGAGCAAAGGGAGCAGCTCGAAAGGCAcgaattgctgctgcagcagcaacaacagcaacagcagcaacaacaacagcagcagcagcagcagcagcaacaactgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAACTTCATGCTCCAGCAAACACCCGGTTTTCCTTTCTTTGGGTTTATggcgccaccgccaccaacaacggcagtagcagcagcagcagcagcagcagcaacagcagcagacaagtcaatgacaacaaatccaacagtagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCACTGCCTGTGCCACTACCCGCTGGTGGCCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATgccaaagcagaagcagcgacgCTATCGAACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCCTCGAATGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagcagccgctgccgccgcagcaATGAGTAAtctcagccagcagcaacagttgcagcagcagcagcaacagttgcagcattcgcattcacatcaCGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttgGCGCAACAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCTCTGGCACATGGCTCCAGCAGTGTTGTCACCAATCCGCTATTGCATTttagctacaacaacaacaacagcaacagcatcagcaacaagcagcagcaacaacagttgagCAACAACACTGGCAACTCTCTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCgaggacgatgaggatgaggaggaggagcaagaatttgatgttgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgaggatattgatgatgatgatgatgcagcagcaacagcagcagcagcagctgcagcagaggcgtcacagcaacaattgcagccaaCCCAGGACAAGCTACAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCTGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGCCGAGAAGCAGCCTCCTCAATCGGATTCCTTGGCCGGCAATAAGCCGGcgacgccaacaacaatgaaaacgaTGATTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTACCGGTAGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTCGTTGCCAGTGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGACACCAAAAAGAAGTCCGCCTACAGCCTGGCACCGAACCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTTACCACGAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCTATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGTCAGGCGGCCGAGGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACGTGAACTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACAACAGTTGCGCCAACAAatggccgctgctgcagcggctgctgtcgctgttgccactgttgctgcacCGGCGCATCCACCACCGCCAGACCAATCGCCACCGGGCCTGGAGGCAAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCATTCGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCGccctgctgctggccaagggTGCCATCGAAACGGATGCACAGCtccagcaccaacagcagcagcagcaacaactgccagCGGCTGGTGGTGCTCCACATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGAAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGCGGCGAGCTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCTTCAACGCCAACGCCccctaacaacaacaacaacaacaacacttgccagaataacaacaataataacaacaacaacaacaacaatagcaatagcaaacaGGTGCTGCGCGAGCTGCTGGGCAAGGCGCACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagcagcagcagctgctgtggccAGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTTAACAAACTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTAGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQQQQQSHTASATAEAAATHEDARDLGLTETRQRRDSSTSESSLEHLDLGRTPKKLTSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHQQQQQLPLSDEEQQQQQQQLLDSSAQRPRHKQRRSGVTGAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNNNNNNNNNNNNNNNISNSSSSSAVAQSAAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQSQQQQQRRQQHAGGAGATGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNNSHKTNNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDADSDADSADSVAQVITSTPDVATLLASGDTSPTHSHSDSHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESEMEEEQQQQQQHEEDPEQQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDVSCEENKSRTEADILTELSGYRCVTPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTVAAAAATPSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQQQQQQQQQQQQQQQQQLFGAGDAAAQYMQQLLRNFMLQQTPGFPFFGFMAPPPPTTAVAAAAAAAATAADKSMTTNPTVAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRHRSGHHVMRERAASSNAVQAAAAAQAAAAAAAAAAAMSNLSQQQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVTNPLLHFSYNNNNSNSISNKQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEEDDDEDIDDDDDAAATAAAAAAAEASQQQLQPTQDKLQSKPIEAAKKVAETILEQAIKEREEKAAEKQPPQSDSLAGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAVATVAAPAHPPPPDQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQQLPAAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPPNNNNNNNTCQNNNNNNNNNNNNSNSKQVLRELLGKAHEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -