Basic Information

Insect: Drosophila phalerata
Gene Symbol: Hivep2
Assembly: GCA_951394115.2
Location: OY729850.1:18410449-18419447[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00021 0.021 15.8 0.3 1 23 243 265 243 265 0.98

2 8 0.00032 0.031 15.3 2.9 1 21 271 291 271 295 0.89

3 8 0.028 2.8 9.1 0.1 1 19 929 947 929 950 0.93

4 8 2.8e-06 0.00028 21.7 2.0 1 23 1693 1715 1693 1715 0.99

5 8 1.2e-05 0.0012 19.7 5.3 1 23 1721 1745 1721 1745 0.92

6 8 2.2e-05 0.0022 18.9 3.5 2 23 2205 2226 2205 2226 0.97

7 8 0.00081 0.08 14.0 1.2 1 23 2232 2256 2232 2256 0.91

8 8 0.0026 0.26 12.4 2.7 1 23 2277 2301 2277 2301 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00021	0.021	15.8	0.3	1	23	243	265	243	265	0.98
2	8	0.00032	0.031	15.3	2.9	1	21	271	291	271	295	0.89
3	8	0.028	2.8	9.1	0.1	1	19	929	947	929	950	0.93
4	8	2.8e-06	0.00028	21.7	2.0	1	23	1693	1715	1693	1715	0.99
5	8	1.2e-05	0.0012	19.7	5.3	1	23	1721	1745	1721	1745	0.92
6	8	2.2e-05	0.0022	18.9	3.5	2	23	2205	2226	2205	2226	0.97
7	8	0.00081	0.08	14.0	1.2	1	23	2232	2256	2232	2256	0.91
8	8	0.0026	0.26	12.4	2.7	1	23	2277	2301	2277	2301	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTGGCAAGTAACTCATCGGGCCAAGTtgccacaacaaccacaacgaaTCATGCGGTTGTGCCAGTCAATGCGACGGCAACAGTCAGCGATGAAGCAACCGCAGCTGCAACAATTGCCGATTGGGCGAATACAACAACTAATTTGCGTTATTTGCACAAGAAATTCAAACGTTTGGCGAGCACCACCGAAGCAGAGGCTGTTGATGTGGTGCGCACCACATCGTTGTCATCAAATAGCTCCATAtcgccaccaccaccaccagcagcagcagcagcaacaacaacatttgcagcagcggcagcaacagttgtGCCGGTGTCGATGTCATTGGCGGTGCCATTGCTCAATGGTCATGTGACGACGACAAATGAATTCAGTgccaattttataaatgaagagagccacaacaacaacaacaacaacaacagcagcagcagtagtaAAAATGTTGTTAGTGCGCCAAGAACGCGTACACCGctcagcaataacaacagcaacagtaactaTGCCAGCAATGCAACATTATCGCCAGCAACATTCGCACAGCATCAGCAATCAACGCAgccaacaacattaacaacaacagcagcagcaacaacaactgttaccgcaacagcaacactgcAAATACAGCCGCAACAACAAGctgctgcaacagcaatagcaacaacatcagcaaccacaacaacaccTGCCGAGAAACCGGGACGTTATATATGTCCCTATTGCAATATGCCATGTGCCAAGCCATCGGTGTTGCAGAAGCACATACGTGCGCATACAAACGAACGTCCGTATCCGTGTGACACCTGTGGCATTGCCTTCAAAACGAAGAGCAATCTCTATAAACACTGCCGTTCCCGTTCACATGCGGCACGAATGCGAGGCATCGATGTGCCCGCCAATGAGGCGGATGGTCTATCCGATCAGGATGGCGATGGCGAACTGAGCAACAGCAGTTCCGAGCTCCTAAGTGTGGAAATTCTAAGTCGTGCGGAGTCGCCTTATGACGAGCCCATGGCATCGCCAACGCCATCTCCATCAACATTGTCGGCGGCGAAGAGCGCGTACCTGCAACAGCCGCCATTGCCGCAGCATTTGCAACAGTTGCCGCTGGGCTCGCCGGCAGCAGGCACATTGCCGCCGCCAACAGCAGATACGTTGCACTCGGCAACGGCGCAACATCGGCAATCGATTGATTACAAGCCATATAAGCCCAAGTTTCATAATGCAGCGCTTTATGCgcctggcagcagcagcaaggaGCAGCAAGTGCAATTGCAGgtgctgcaacagcaacagcaggcattacagcagcagcagcagcatcaacaacaacagcagcaacagcaacagcagaagTTGGCGTCGCAGCAACCAACATTGGCACATCCAACACTATCGCCGAGCACGCAGTTGAAGCTCAACAATCACATCAACTCACATCAGATGCAATTGCAGctacaacatcagcaacaacaacagctacatgCACAGCAATCATTGCTGCTGGCGGCAGCTGCTAATCCTGCGGCATTGACGGGATTACCACCACCACAGACCATGCCCACAAGTGTCTACTATTTGGGGCAGCCGCAGTATTTTAATCATACAATGCATCAACAGGCGTTAGCCTTTCAGCAAATGCAGTTCCAGCAACACTTCCAActccaacaacagcatcagcaccaacaccagcaacagcagcaacaccagcaacagcagcaacaccagcaacagcaacactcaCCGCTGTTGAAGGCGCCTACACATCCTCCGCAACCACAGCCACAACCACAAATGCAACCACTACCACCACAGCCATTGCCACAACCACAGCAGCTGGTGCGTTCAAACAGTCAACAGGCGTcgataacagcaacaacagccgccGTGTTGCCAGcccctgccacgcccacgcctCCAGCCAATTTGAGCAGCTTTGCCAGCGCCAGCGGTGGCATGCAAGTGAATGTGGAGAAGGTGCAGGAGCACATCTCGAAATTGATCTCACAGAACGAGGCCATAGTGGAGAATAAGGAGATATTGTTGCAGAAAAAGTATCCCAAGCAGTTGAATCGTTCGCGCAGCTTTaacaatgccaacaacaataacagcaatatcaacagcagcaacatcaacaacaacaatgcctcGCCtcacatcagcagcaacaacaacagcaacaataacaatgctcAGCAGATGGGCGAGACCAAAGTGAATCTGGCACAGGCCATAGttcaaaagcagcagcaacaacagctgcaacaacaacagcagcagcagcaacaattgctgcagcaacaacaataccaaATGTatttgcaacagcagcagcagcagcaacaactggaGCCTGTCAATGGTTTGCTAAAGCGTAGCTCCAACTATGTGGGCCTTAAAGgctctgccacgccccttgcAACGCCCAATGCCAAGCTGCAACAGTTGCCGCTGCCGCCATCGCCGTTGCCACTGCAAACGTTGCAATATCGCCAGGATCCCGCGACGCCAGTGCCCAAattggagcagcagcagcaacaaactaCATCAAATCATGTGCAACCTCTTAATTTGTCTGCGAAACCaaagccagtgttgccacaaaaagtggcagtagcaacagcaacagcaaccagtGTTGCTGCCACCTCAGTGGTAAAGAGCACAACAGCAATGCAACAGtcaaataattcaattattaaGAATCTATTGCTGAATGCACGCGGTTTGGCTGTGCCCATTGGCGAGGGCGATGATGCCGTCTATTCGTGTCCCATTTGTGCCAATGAATTTCGCAGTGCGGATGAGTTGAAGTTGCATAACAGCACCTACTGCCAGGATGCCAGCAGCAGTGCCCCAATGAGTCCAGCCTCATCGCCAAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTCAGTTTGCCCGAACTCAAGACCCACATGGCCAATTCAAAGAATCCATTGTCTTTGGCCAAGTTGGCCTGGTCGCAGCTAAAGACAAAACCGAGCAGTCTAGTGTTGAGTCGTCTCAGTGCGGCACAGTCGCCGGCACGCACCTCCACGATCACCTCAACcagcaatagcagcagcaaccacaacagcggcaacagcaaccacaacaatagcagcagcaacaacaacaattgcaacactatcagcagcagcaataacttGCCTTTGGCCACGCCTGCAATTGTGCCGCCCATCATTGATGCCGCCAATGTTGCCCTGCGTTTTGTGGATGCACCTTTACCGTCACCGGGTCCGCTCTTGGGCAAAACACCGCTTGTGGATTATGCGGCACCGCGCAAGACGCAGGACACCCAAGTGGTGATAACCAAAATGCACGAGGATCGTCTAGAGAACATAATCATTGAGACGCCGGCCAAGCGTGTGAAATTGGGCAACGACATTGGCAGCAGCAATAGCGGCAGTGGAAGCCTCAGCTCGACAAGCTCTGCCTTTGTCTTGCCGGCAGCGGTGCAGTTGATCTATGGCGGCAATCAGGAGCAATTGCAGTCGTCGGGCAGCAGTTATAGCGCCAAGGAGGAGCGACTGCGTCGGTTTACCTCCTCTGGCGGCAGCATGATACCCATCTCCGAGTGTCCTGAGCTCAACAAGAGTCCCAAAATGATACGCACTCCGTTGTTGTCCGGCGGCAGCTTTCAGGAGATGTCGCCACGTCCCAGCGACTCAAAGGAGCGTAAACTATCTACGCCAAATAATGGATTCCTACTAAGCTCCTCCACCACAACGCcacaacattttcaatttccgCCCATCAATTCCATAACTGCCTTCAATCCGTTGACATTGCCGCccatgagcaacaacaacaatgttggTGAAGCCAGCAAGGCAATACCCTATGTGCCGGGCATACCGGGACCGGGTAGCTTGTCATTGTTGCCGCCAccgcaacaactgcaactgccggcagcagcaacacgtGGACGCAGTCCCAATCGCAAGCAGCCAAGTCCCAATCTGTTGCTGGAAGCGCCGCTCAAGGCATTGTCACCATTCGGTGGCGTACAAAATGTGCCCAGCGAATTCAGTCGACAGCCGCCGACTCCAGCGCAACGTAATGCGCTGCAAtggaacagcagcaacaaggcaGCAGCAGGAGGATCTTCAGTAGGAGCAGCAGGAACAGCTGGAGCTACAACTGGACTGGACTTGAACAAGAAGCAACCATTTAATTTCCTGCGCATGGCCGACAATGTCAAGAGCTGCTCCACCTCGGAACTCACTGTGCCCGAGGTGCGACACTTTAATTTCGATAATGTACACAAAACGCAGGAGGCGCTGGCGCCGCTGCACGTGGACACGCCGGAGGAGCTGGCCAGCAACACAACGGCAACATCAACCACAACAATAATTACAACTCCAACCAGTGCCAAGTCGAAATTCCTGCGTCCCACCAGTCTGCCCCTTAAGCCGGGCACTTTTACGCCCAAGCGTCATCACGGAATTACGCCCACGGCAAATACGTTGCCATTGATCTCACCGGAAACGCCGCGTCCATCGAAATCATGTGTGCAGTTGTATTTGAATGGTCATGCCTACACTTATCTGGGTCTCAAGTGCAGCACCAAGATGTTCTACTGTACAGTAAACTGTCCACAGCCATCGTATGTCGCTGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAAGTGTGCGAGGAGAATCAACCGCATCCGTTGGGTTTCAAGCCCAAACAAGTGATGGCTTTGTATGATTCCAGGCAAAAGATGCTTGGTAGTGGTTCCTTTATGGCCATGGCCGGACAGGGCAAGATGTCCTACTCTGTGGTTAGTTCACAACAAACTGTGAGCACCTGTTCCACCATCGCCAATGGACAGAATAAGTTCTATCAGCATCAGTTAAAGCAACCACCGGCAATTGCCACATTGAGTGAGGCAAATGTGGCAGCCAAGGCAGCGAATGATGAGGCAGCAGCCAAGAAATTGGAGTCGGGACAACTACTTGTTGGTGGCTATGAGTCGCATGAGGATTACACCTACATACGGGGACGTGGACGCGGTCGTTATGTGTGCTCCGAGTGTGGCATACGTTGCAAGAAGCCATCCATGCTCAAGAAGCACATACGCACGCACACGGATGTGCGTCCCTTCACCTGCAGTCACTGCAACTTCAGCTTCAAAACAAAGGGCAATCTCACCAAGCACATGCAATCGAAGACGCACTTCAAGAAGTGCATAGAGCTGGGCATCAATCCTGGCCCCATGCCGGCAGACGGTGAATTCCTCGATGTCGATGTGGAATTCGATCAGCAATCTTCAACTTCGGCCGGCGGACGCACTTCCTCCATGGCTGGTGAATCTGATTCCGATGATTATAGCGACAATGAATCCGAGAGCAGCGACACTGATGAGTCCAAGTCGCGCCTAAAGGAGCACGAAGCAGCACGTGGCCTGCTCTCGTTGTCCATGACACCGCCAATACCGCAGAGTGTTTCTCCATTTCCCTCCCAGCTGCAGGATACTCCTCTGCCGGCTGCCAGTCCGGCGAATAGCATTGGCTCCTCCGCCGGCAGCAGCAGTGCAGCGGGAAGTTCTCAACCCAAACGTCTGGTTTGCTCATTTACATCACCGAAGCCGCCATTTGATTACCAGAAGCAAGAACAGTATTACTCCAATCCGGAGGAATCCAAGCCGAAGCGTGGCGTGCCCAACGATGAGAGCAGTGCTCCCATGGATCTGACCAAGCCAAGATCCTCTGCTGGCCAATTGGCAGCCTCATCAGCTGGATCTTCGCCGGTGGAGCAGCTGCCTGCCAAATCTCAGGCCCAACAGATGCGCGATGTTATCTTTGGTACCGGGAATAATGAATCTGGCTTCATGAAGACACTCATCTCGGTGTCCGACAAGGTGCGCATCTCAGCGGAAATGGAGGAGCAGGCAAAGCGCGAAACTGAAGGTGATGATGTGCTCCTGCAGACCTACATCAAGGAGCAGGCACTGCAATATGCCAAAATGAAGCAGAGTCAGTTTAGTCGCAGTTACCTGGTCAcaagcaccagcagcagctcGGCAGGCACTCCAATTGTGAGCAGCAGTCTCCATGTGTTGAACAAACAGCCAATGATCATCACAGAGCTGCCGAGCATTGAGGTGCATGAGGTGAAGACACCAGAGCCGGTTGCCATTGTCGAAGCCACGCCAGCGGCAGTCGAGGAGATGGACGAAGTCGAAGCAGGAACAGGAGCAACTGTGGAGCCGGAGCAGACAACGCCTGTTGCTGTCAGCGTAGCTGTCTCCATTCCTGTTACCGTCTCCATATCGAGCGCAAAGCAGCTGCCTCACAATGCCAACTTACCGGCTGCAGTGCAGCAACCAGATGCCACCGATTTTAGTGGTGTgctcagcaacagcaacaacaatgctgcaacaacaacagcaactcctGCCGCCCGCACTGTTATCGTTGGCGAGGAAGTCTTCAAGCCAACTCCAACGAGTGTCGCCGCCGAGGTGACTGCTCCAGTTTCCGTCGCCTCCACAAGCTATCCCGGTCGCGTTGTGccaccaccgccgccgccAATTGCCGGTGATGCGCGTCCCACGTGCAGCATCTGCAACAAGACGTTCCAGCGGCAACATCAGCTAACGCTGCACATGAACATCCATTACATGGAGCGAAAGTTCAAATGCGAGCCTTGCAGCATCTCGTTTCGCACGCAGGGACATCTCCAGAAACACGAGCGTTCCGAGGCGCACAAGAACAAGGTGATGATGACGTCGACATTTGGTGTGCCAACCACATCGAATCCACGTCCATTTGAGTGCACCGACTGCAAGATTGCCTTTCGCATCCACGGCCATTTGGCGAAACATTTGCGCTCCAAGACGCACGTGCAGAAGCTCGAGTGTCTGCAGAAACTGCCATTTGGCACCTATGCGGAGATTGAGCGCGCCGGGATCAGTCTGACTGAGATCGATACCAGTGATTGCGAAAACTCACTGATATCACTCAAGCTGCTGGCCCAGAAGCTGCTCGAGAAGGATCCCAATAAGCTGAGTGGTTATACCACGCCATCGGGCATGATGCAACTGGGATCGGATACACCGGCAGCTGGGCAGGACAGCGCTTCCGAGGATGGCTTCAGTGCGGCGAATAGTGCAGCTGCCTCGGCAATTGCATCGCTGGATAACGACAGTGCGGGCAACACGCCACAACGTGCCAGCTCCATGTCCGAGGATGAAACACTGGCCAACGGACTCAGTCAGAGTCACAGCCTGAAGCGTCGTCTGCCCGGCAGCAGCTTTAGCAGCAATGGCGACGAGAGCGACAATCCGCTGGAGGGCAGCGAGAAGCGGGCGAGAAGCAACACCAATGAGCAACTTACTCACCCAGTGGCGGCATCCACAGCAACAGCGAGCAACTGA
Protein Sequence: MTLQHVASNSSGQVATTTTTNHAVVPVNATATVSDEATAAATIADWANTTTNLRYLHKKFKRLASTTEAEAVDVVRTTSLSSNSSISPPPPPAAAAATTTFAAAAATVVPVSMSLAVPLLNGHVTTTNEFSANFINEESHNNNNNNNSSSSSKNVVSAPRTRTPLSNNNSNSNYASNATLSPATFAQHQQSTQPTTLTTTAAATTTVTATATLQIQPQQQAAATAIATTSATTTTPAEKPGRYICPYCNMPCAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARMRGIDVPANEADGLSDQDGDGELSNSSSELLSVEILSRAESPYDEPMASPTPSPSTLSAAKSAYLQQPPLPQHLQQLPLGSPAAGTLPPPTADTLHSATAQHRQSIDYKPYKPKFHNAALYAPGSSSKEQQVQLQVLQQQQQALQQQQQHQQQQQQQQQQKLASQQPTLAHPTLSPSTQLKLNNHINSHQMQLQLQHQQQQQLHAQQSLLLAAAANPAALTGLPPPQTMPTSVYYLGQPQYFNHTMHQQALAFQQMQFQQHFQLQQQHQHQHQQQQQHQQQQQHQQQQHSPLLKAPTHPPQPQPQPQMQPLPPQPLPQPQQLVRSNSQQASITATTAAVLPAPATPTPPANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSNINSSNINNNNASPHISSNNNSNNNNAQQMGETKVNLAQAIVQKQQQQQLQQQQQQQQQLLQQQQYQMYLQQQQQQQQLEPVNGLLKRSSNYVGLKGSATPLATPNAKLQQLPLPPSPLPLQTLQYRQDPATPVPKLEQQQQQTTSNHVQPLNLSAKPKPVLPQKVAVATATATSVAATSVVKSTTAMQQSNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKLHNSTYCQDASSSAPMSPASSPSSKYFRSNSISFSLPELKTHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSTITSTSNSSSNHNSGNSNHNNSSSNNNNCNTISSSNNLPLATPAIVPPIIDAANVALRFVDAPLPSPGPLLGKTPLVDYAAPRKTQDTQVVITKMHEDRLENIIIETPAKRVKLGNDIGSSNSGSGSLSSTSSAFVLPAAVQLIYGGNQEQLQSSGSSYSAKEERLRRFTSSGGSMIPISECPELNKSPKMIRTPLLSGGSFQEMSPRPSDSKERKLSTPNNGFLLSSSTTTPQHFQFPPINSITAFNPLTLPPMSNNNNVGEASKAIPYVPGIPGPGSLSLLPPPQQLQLPAAATRGRSPNRKQPSPNLLLEAPLKALSPFGGVQNVPSEFSRQPPTPAQRNALQWNSSNKAAAGGSSVGAAGTAGATTGLDLNKKQPFNFLRMADNVKSCSTSELTVPEVRHFNFDNVHKTQEALAPLHVDTPEELASNTTATSTTTIITTPTSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGSGSFMAMAGQGKMSYSVVSSQQTVSTCSTIANGQNKFYQHQLKQPPAIATLSEANVAAKAANDEAAAKKLESGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPFPSQLQDTPLPAASPANSIGSSAGSSSAAGSSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRSSAGQLAASSAGSSPVEQLPAKSQAQQMRDVIFGTGNNESGFMKTLISVSDKVRISAEMEEQAKRETEGDDVLLQTYIKEQALQYAKMKQSQFSRSYLVTSTSSSSAGTPIVSSSLHVLNKQPMIITELPSIEVHEVKTPEPVAIVEATPAAVEEMDEVEAGTGATVEPEQTTPVAVSVAVSIPVTVSISSAKQLPHNANLPAAVQQPDATDFSGVLSNSNNNAATTTATPAARTVIVGEEVFKPTPTSVAAEVTAPVSVASTSYPGRVVPPPPPPIAGDARPTCSICNKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLGSDTPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLANGLSQSHSLKRRLPGSSFSSNGDESDNPLEGSEKRARSNTNEQLTHPVAASTATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523176;
90% Identity: iTF_00523176;
80% Identity: -