Basic Information

Insect: Drosophila phalerata
Gene Symbol: -
Assembly: GCA_951394115.2
Location: OX596005.2:12386270-12390883[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0017 0.16 13.0 2.0 1 23 209 231 209 231 0.96

2 26 0.1 10 7.4 1.3 1 23 237 259 237 259 0.97

3 26 0.055 5.5 8.2 0.8 2 23 291 312 290 312 0.96

4 26 0.017 1.6 9.8 1.1 1 23 387 410 387 410 0.94

5 26 6.7 6.6e+02 1.6 5.9 2 23 422 445 421 445 0.93

6 26 0.096 9.5 7.4 1.1 1 23 451 473 451 473 0.97

7 26 0.07 6.9 7.9 0.6 2 23 492 513 491 513 0.96

8 26 0.0028 0.27 12.3 2.1 1 23 589 611 589 612 0.94

9 26 0.0033 0.33 12.0 0.2 1 22 621 642 621 642 0.95

10 26 0.066 6.5 8.0 5.7 1 23 651 674 651 674 0.95

11 26 5.7e-05 0.0056 17.6 0.3 2 23 703 724 702 724 0.97

12 26 5.8e-06 0.00057 20.7 3.5 1 23 732 754 732 754 0.99

13 26 0.0067 0.66 11.1 1.1 1 23 904 927 904 927 0.97

14 26 3.2 3.2e+02 2.6 1.6 2 22 935 955 934 955 0.89

15 26 0.09 8.9 7.5 0.5 1 23 964 987 964 987 0.91

16 26 1.2e-05 0.0012 19.7 1.8 1 23 1012 1034 1012 1034 0.97

17 26 0.00014 0.014 16.4 0.9 1 23 1041 1063 1041 1063 0.98

18 26 0.0024 0.24 12.5 0.0 2 20 1090 1108 1089 1110 0.94

19 26 0.013 1.2 10.2 3.9 1 23 1155 1178 1155 1178 0.96

20 26 0.0022 0.21 12.6 1.6 1 23 1215 1237 1215 1238 0.96

21 26 0.00098 0.096 13.7 3.5 1 23 1263 1286 1263 1286 0.97

22 26 1.4e-05 0.0014 19.5 0.1 2 23 1314 1335 1313 1335 0.95

23 26 4.7e-05 0.0046 17.9 2.9 1 23 1341 1363 1341 1363 0.99

24 26 2.3e-06 0.00023 22.0 2.0 1 23 1369 1391 1369 1391 0.97

25 26 5.9e-08 5.8e-06 27.0 2.4 1 23 1397 1419 1397 1419 0.99

26 26 0.001 0.099 13.7 0.2 1 21 1425 1445 1425 1449 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0017	0.16	13.0	2.0	1	23	209	231	209	231	0.96
2	26	0.1	10	7.4	1.3	1	23	237	259	237	259	0.97
3	26	0.055	5.5	8.2	0.8	2	23	291	312	290	312	0.96
4	26	0.017	1.6	9.8	1.1	1	23	387	410	387	410	0.94
5	26	6.7	6.6e+02	1.6	5.9	2	23	422	445	421	445	0.93
6	26	0.096	9.5	7.4	1.1	1	23	451	473	451	473	0.97
7	26	0.07	6.9	7.9	0.6	2	23	492	513	491	513	0.96
8	26	0.0028	0.27	12.3	2.1	1	23	589	611	589	612	0.94
9	26	0.0033	0.33	12.0	0.2	1	22	621	642	621	642	0.95
10	26	0.066	6.5	8.0	5.7	1	23	651	674	651	674	0.95
11	26	5.7e-05	0.0056	17.6	0.3	2	23	703	724	702	724	0.97
12	26	5.8e-06	0.00057	20.7	3.5	1	23	732	754	732	754	0.99
13	26	0.0067	0.66	11.1	1.1	1	23	904	927	904	927	0.97
14	26	3.2	3.2e+02	2.6	1.6	2	22	935	955	934	955	0.89
15	26	0.09	8.9	7.5	0.5	1	23	964	987	964	987	0.91
16	26	1.2e-05	0.0012	19.7	1.8	1	23	1012	1034	1012	1034	0.97
17	26	0.00014	0.014	16.4	0.9	1	23	1041	1063	1041	1063	0.98
18	26	0.0024	0.24	12.5	0.0	2	20	1090	1108	1089	1110	0.94
19	26	0.013	1.2	10.2	3.9	1	23	1155	1178	1155	1178	0.96
20	26	0.0022	0.21	12.6	1.6	1	23	1215	1237	1215	1238	0.96
21	26	0.00098	0.096	13.7	3.5	1	23	1263	1286	1263	1286	0.97
22	26	1.4e-05	0.0014	19.5	0.1	2	23	1314	1335	1313	1335	0.95
23	26	4.7e-05	0.0046	17.9	2.9	1	23	1341	1363	1341	1363	0.99
24	26	2.3e-06	0.00023	22.0	2.0	1	23	1369	1391	1369	1391	0.97
25	26	5.9e-08	5.8e-06	27.0	2.4	1	23	1397	1419	1397	1419	0.99
26	26	0.001	0.099	13.7	0.2	1	21	1425	1445	1425	1449	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACCGATATCTGCCGGACATGTGCATTAAATGATGTAAACTTGTTAGAGCTTTCCACGCGCAATgagaaatatgcaaataaaagttttcatGACATGTTGCATGAGCTAACACAAAACGATccCTTAATGGAACACTCCGAGGATAATCTGCCTCAGTATTTGTGTACTGAATGCATACGTAAGCTGGAAGATGCTTTCGCATTTGTGATGCAAGCACGTCAGGTGCAGGAGCAACTGTTGCACAAAATTCGCAAAGGATTACAGTGTCTGGATGAGACGCCTATAGACATTGCCCCGCAATACATAAAGACAGAAGCCGACATTGCCTTGGTGCAAAACAAGGACGGCGATGAAGATAAAATTGCAACTGAGTCTGTTGCAGCTCTAAAGATACAACCGGGGAGTGAGAGCGACAGTAGCCAAGAAGACGCGGCTGATGATGATGTGCTAGACTTTAAGCCCACACAGCTGAGACGTAGCTCTCGGAAGATCAAATTTGGCACAGACAGCGAAAATGAAGTACACTCTGAAAAGTCAAACGCAATGCCTGTCAAGCGTCGTCGCGGTCGCCCTCCACGTATTCCCAAACAGGAAACCATCAACAAGGACGGTCGCCATGCCTGCGAGGTGTGTGGCAAGACGTTCTCGTGGCATCGCGACATGCAACGCCACGCTCGCGTCCACTTTGAACAGGCTGGCTACGTGTGCGACAGCTGTGGCAAGGGATTCCTCCGCAAGGACAAGTACATGTTCCATTTGCGGTCGCACGAGAAGCGCCAAGCCAAACGGCAGGCTTTGCAGCTGGGCAACGAATGGCGCTTTGCGGAACGCCTGTACAGTTCTGGACGCCTCAAGCGTGTCGAGTGTAAGCTGTGCGGCTTGAAGTGTCAGCGGATTCAGGAACTTCGTGAGCATCTGTCCATTCATGTCAGCATTGAAACATTGTCGAATCTCAGCGCCAATAGCGATGTTATCGTGGAACAGTTTACCAGCCAGTCGATAGACTTGATGCAGATTAAGCAACAGGTGTGTGCGGACATAGCCAAGGGAAGTGAACATTTGGATAAATACTGTGTGGTGGTCAATGCACATGGCTATGAACTCTGTCTGAGTGACTCCGACGAAGAGTTACCAGGAATGCCGCCTCCTTACCAATGCCTGGCTTGTAACACTCTATTCTCCCGCAAATATCGCCTGATGCGGCACACGTTGGAGGAGCACACCCAACCTAAAGCTGAGGCAACTCCCTGGCAACGTTGCAACTATTGTCATATTGGCTTTGTGTGCGTTAGGCTGTTGGAACAGCACCAGCGCACACAATGTCACAATCAATTGAAACGTTATAGTTGTCCCACTTGTCCAGGCAAATTTATTTGGCGGCAAAATCTGAAGCAACACGCGTGCTCTCATCTTACGAGCTCTTTAGAGGCTAGAGAACAGGAGAGAAGTCTAGGTCGACAGATTCAGTGTTGCCTTTGCGATGAGCAACTGGAAAGTATGTCAACACTACGTGCTCATCTTGTCACACATTGCGATGGAGAGAGGGGCATTGATCCAGATCGAGGATCTACCTTCTTTCGTTGTAATTATCTAGAGAGTTCTACCTACAACCAGACGGAACTCAGCATACGAATTGCAAGTGATTTCGCGGCCGAGGATTATGGTCGCTACTTCAATGCCTGCACAGGCAGCGGCCAAGAACTGGATTTCTTTGACTCTGATTCGGATTCAAGCGATCTGTCAGGTGCAGCTGTGCATTCGTGTGCTTTGTGTGGTCAAAGCACAATACGCCTTGCCCAACTCCTGAAGCATCAGCAGAATCATCACAGTGAGGTGATGGACACATTGCCTCATGTGTGCGACAAGTGTGGACTGGGATTTGTAGCTGAATCGCTGCTTCAGCAGCATCGTCGACGCATCTGTGCAAAGCGGCATGCTAAGTATCATTGTCAGCATTGCAATCTCCACTTTATCTGGCAGTCCAATTATGAGCGACACATGGAACTGCAGCACGAGGCGGTAGCAGAAACAGATGATGTCTCAGATCTTGTGCCCAATACCAGGCTAAGAAGCAAACGTCAACAAGCTGCCAAATTACAGTGTAATGAATGTGATAAGGTCTTCATCTGGCCTAAGGATCTGACGCGTCATAAACGCATTCATCAGCCGCAGGCATCGGCGCAGTACGAATGCAGCTACTGTGAGCGCAAGTTTCATCGCAAGGATGGGCTAAAGTCCCATATGCGTGTTCATGGAGAGCCCCATTTGGATGCGACAATTATGACCAACAGCGATCCGGATCCGTCAATGCTACAGCGAATGCCAATGGTGTTGATGCAATTGTGCCAACCGAATGGATGCAAGCTGATTCAATGCATGATCTGTTTATCTCAGCACTCGAAGATCTCTGATCTGCGCACGCATTTGGTGAAGCATCAGTTTGATGTAGAGTTTGCAGAGGAGCGTGCGAATTCGGAGAACATTTCTAGTATTTGTCGGGCCCTATATCCGGATCAGGTGACTCCTTTGGATAAGCAACAACTGATTGAACGCATCCAGAGAGATGTGGGTAAAGGCACTGAGTTGGAAAGATTCATTTCGATTACCAACGAGGCAGGCATTGAGCTGAGCTTAGACAGCAgcgaaactgaaactgattcGGATTCAGCCGAAGTGGAAAAGAACAGCAGTGTACGGCAATACAATTGTGAGCTATGCAAATTGAAGTTGCCGCGAAAGTATCAACTATATGCTCATCAGCTGAAGCAGCATACATGGCAACAGGCCACCCACATTTGCATCCACTGCCAGGCCAGATTCATCAATGACCAGTTGCTGGAGCACCACTATCGTAGTCTCTGTCGCAATGTGCACAAGCGTTTCCTTTGTCGGAAGTGCCCATTACGCTTTCGCTGGCGTGACAACCTCAAGCTGCATACAGACGTGGCACATCAGGAAACCACTGTAGAACAGACTAGCTTGGGCATCCAATTGAATGGGACAAGTCTTGTTCCTGTTGTCAGCTACGATTGCAGCGAGTGTAATCGCAgctttaaaatgcaaaaggaTCTCACACGTCACACGCTGATGCATGCCCAGGAGTCGAGCATTTACCGGTGTCGTTGGTGTGCTCGTCGCTTCTATCGCCAGGCTAATCTACTGCAGCACATTGAGCGTCATGGCATCAATGCCTCACAGCTGCCGTATGCCGAGTCCCTGCTCAATGCCAGCCGTCATCCAAATGGTCAGAAGTGTGTCCAATGCAAGGTGTGTGATATACGTTTTCCCACAATTTCCGCACTTCGTTCCCATTTGGCGTCCATACCGAGCGGGACTCATCATGGGATTGAATCCATGCTCAACTACTCGATTACAAATCAGCTGGGCTATGAACTGCACTTGGAAGACTCGGAAACGGATGAGGAGACTAAGCCGCCTGGTATTCCCTCACACTACACCTGTGGCATGTGCCAGCTGCGTTGTGTACGGAAGTATGAGctgcatcagcatcagcaggcCATGCATCGATTAGAGCGGATTACTGAGGGCTGTGATCTGTGCATCTTTAAGAGTGTTTCCCCAGATCTTATCGCCTATCATCGGCGTGTACAGTGTTGCAACACGGAGAAGCAATTCAAATGCGACAACTGTGGCTACAAGTTCATGTGGGAGTCCAATCTGTTACAGCACATTCAACTTCACCATCCTGGCAATATAGATCAAAAGGAGATGTCAGCGGGGCCTGCACCGGAGACAACCACTGTGGAGTGTCAGATCTTTCAGTGTGGGCAGTGCCCACGCAAATACAATCGCAAGGATCGACTGACAGCCCATGTAAAGAAGTGCCATGCACCAGGAGCTGTTGGTCAAACTGAGCATCCAACGAGAACATCGACGTCCTCAAGTGTCGCAAAACCACAGAAAAGTTTTCTCTGCGCCTTTTGTGGCAAAGCGGTGAGCTCCTCTTCTAATCTCATTATACACATACGTCGTCATACTGGCGAGAAACCCTTCAAGTGCGACTATTGCGACATGGCTTTTCCCCGTTCATCGGATCTGCAGTGCCATCGACGCACTCACACTGGTGAACGTCCTCATGTTTGCACCGTGTGCCAAAAGGGATTCGCCCGCTCCTACAAGCTTCAGCAACATATGCGCATCCATAATGGTGAACGTCCCTACAAGTGCACATACTGCGACAAAAGCTTCACCCAGTCCAATGACCTGACCCTCCACATTAGACGACACACCGGCGAGCGACCTTATCAATGTGACACCTGCGGGGAACGTTTTATTCAGGGCACAGCACTCAAGAATCATCGACTACAGAATGGACATTACGAGGCAGTGGATGGCCTAGCTAAAGTTAATTAA
Protein Sequence: MLPTDICRTCALNDVNLLELSTRNEKYANKSFHDMLHELTQNDPLMEHSEDNLPQYLCTECIRKLEDAFAFVMQARQVQEQLLHKIRKGLQCLDETPIDIAPQYIKTEADIALVQNKDGDEDKIATESVAALKIQPGSESDSSQEDAADDDVLDFKPTQLRRSSRKIKFGTDSENEVHSEKSNAMPVKRRRGRPPRIPKQETINKDGRHACEVCGKTFSWHRDMQRHARVHFEQAGYVCDSCGKGFLRKDKYMFHLRSHEKRQAKRQALQLGNEWRFAERLYSSGRLKRVECKLCGLKCQRIQELREHLSIHVSIETLSNLSANSDVIVEQFTSQSIDLMQIKQQVCADIAKGSEHLDKYCVVVNAHGYELCLSDSDEELPGMPPPYQCLACNTLFSRKYRLMRHTLEEHTQPKAEATPWQRCNYCHIGFVCVRLLEQHQRTQCHNQLKRYSCPTCPGKFIWRQNLKQHACSHLTSSLEAREQERSLGRQIQCCLCDEQLESMSTLRAHLVTHCDGERGIDPDRGSTFFRCNYLESSTYNQTELSIRIASDFAAEDYGRYFNACTGSGQELDFFDSDSDSSDLSGAAVHSCALCGQSTIRLAQLLKHQQNHHSEVMDTLPHVCDKCGLGFVAESLLQQHRRRICAKRHAKYHCQHCNLHFIWQSNYERHMELQHEAVAETDDVSDLVPNTRLRSKRQQAAKLQCNECDKVFIWPKDLTRHKRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGEPHLDATIMTNSDPDPSMLQRMPMVLMQLCQPNGCKLIQCMICLSQHSKISDLRTHLVKHQFDVEFAEERANSENISSICRALYPDQVTPLDKQQLIERIQRDVGKGTELERFISITNEAGIELSLDSSETETDSDSAEVEKNSSVRQYNCELCKLKLPRKYQLYAHQLKQHTWQQATHICIHCQARFINDQLLEHHYRSLCRNVHKRFLCRKCPLRFRWRDNLKLHTDVAHQETTVEQTSLGIQLNGTSLVPVVSYDCSECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINASQLPYAESLLNASRHPNGQKCVQCKVCDIRFPTISALRSHLASIPSGTHHGIESMLNYSITNQLGYELHLEDSETDEETKPPGIPSHYTCGMCQLRCVRKYELHQHQQAMHRLERITEGCDLCIFKSVSPDLIAYHRRVQCCNTEKQFKCDNCGYKFMWESNLLQHIQLHHPGNIDQKEMSAGPAPETTTVECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVGQTEHPTRTSTSSSVAKPQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQNGHYEAVDGLAKVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558059;
90% Identity: iTF_00507018; iTF_00523088;
80% Identity: -