Dinn002679.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila innubila
Gene Symbol
-
Assembly
GCA_004354385.1
Location
NW:6796053-6800486[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.075 4.2 7.6 1.3 1 23 14 36 14 36 0.97
2 25 0.036 2 8.6 1.1 2 23 68 89 67 89 0.97
3 25 0.0025 0.14 12.2 2.2 1 23 164 187 164 187 0.94
4 25 4.1 2.3e+02 2.1 6.1 2 23 199 222 198 222 0.93
5 25 0.15 8.6 6.6 3.8 1 23 228 250 228 250 0.98
6 25 0.051 2.9 8.1 0.6 2 23 269 290 268 290 0.96
7 25 0.0033 0.19 11.8 1.8 1 23 366 388 366 389 0.94
8 25 0.055 3.1 8.0 0.1 1 22 398 419 398 419 0.94
9 25 0.048 2.7 8.2 5.7 1 23 428 451 428 451 0.95
10 25 0.00015 0.0083 16.1 0.3 2 23 480 501 479 501 0.97
11 25 4.2e-06 0.00024 21.0 3.5 1 23 509 531 509 531 0.99
12 25 0.0096 0.54 10.4 0.7 1 23 681 704 681 704 0.95
13 25 0.043 2.4 8.3 2.2 1 22 711 732 711 732 0.94
14 25 0.066 3.7 7.8 0.5 1 23 741 764 741 764 0.91
15 25 8.7e-06 0.00049 20.0 1.8 1 23 789 811 789 811 0.97
16 25 0.0001 0.0058 16.6 0.9 1 23 818 840 818 840 0.98
17 25 0.0068 0.39 10.9 0.0 2 20 867 885 866 887 0.93
18 25 0.0092 0.52 10.5 3.9 1 23 932 955 932 955 0.96
19 25 0.0019 0.11 12.6 0.5 1 23 992 1015 992 1015 0.96
20 25 0.00071 0.04 14.0 3.5 1 23 1040 1063 1040 1063 0.97
21 25 1e-05 0.00057 19.8 0.1 2 23 1091 1112 1090 1112 0.95
22 25 3.4e-05 0.0019 18.1 2.9 1 23 1118 1140 1118 1140 0.99
23 25 1.7e-06 9.4e-05 22.2 2.0 1 23 1146 1168 1146 1168 0.98
24 25 4.3e-08 2.4e-06 27.2 2.4 1 23 1174 1196 1174 1196 0.99
25 25 0.00073 0.041 13.9 0.2 1 21 1202 1222 1202 1226 0.91

Sequence Information

Coding Sequence
ATGCAACGTCACGCTCGTGTCCACTTTGAACAGGCTTGCTACGTGTGCGACAGCTGTGGCAAGGGATTCCTCCGCAAGGACAAGTACATGTTCCATTTGCGTTCGCACGAGAAGCGCCAAGCCAAACGGCAGGCTTTGCAGCTGGGCAACGAATGGCGCTTTGCGGAACGCCTGTACAGTTCAGGACGCCTCAAGCGTGTCGAGTGTAAGTTGTGCGGCTTGAAGTGTCAGCGGATTCAGGAACTTCGTGAGCATCTGTCCATGCATGTCAGCATTGAAACATTGTCGAATCTCAGCGCTAATAGCGATGTTATCGTGGAACAGTTTACCAGCCAGTCAATGGACTTGATGCAGATTAAGCAACAGGTGTGTGAGGACATAGCCAAAGGACGTAAACATCTGGATAAATACTGTGTGGTAATCAATGCACATGGCTACGAACTCTGTCTAAGCGACTCGGACGAAGAGATACCAGGAATGCCGCCTCCATACCGATGCCTAGCTTGTAACACTGTGTTCTCGCGCAAACATCGCCTGATGCGGCACACGTTGGAGGAGCACACTCAACCTAAAGCTGAGACAACTCCCTGGCAACGTTGCAACTACTGCCATATTGGCTTTGTGTGCGTTAAGCTGTTGGAGCAGCATCAGCGCACACAGTGTCACAATCAGCTGAAACGTTATAGTTGCCCCACTTGTCCAGGCAAATTTATTTGGCGGCAGAATCTTAAGCATCACACGTGCTCCCATCGCACGAGATCTTCAGAGGCCAGAGATCAGGAGAGAAGTCTAGGACGACAGATACAGTGCTGCCTTTGCGATGAGCAACTGGAAAGTATGTCAACACTACGTGCTCATCTAGTCACACATTGCGATGGAGTAAGCGGCATTGATCCAGAGCGAGGATCAACCTTCTTTCGTTGTAATTATCCAGAGGGTTCTACCTGCAACCAGACGGAGCTCAGCACACGAATTGCAAGTGATTTCGCGGCAGAGGATTACGGTCGCTACTTTAATGCCTGCACAGACAGCGGCCAAGAACTGGATTTCTTTGACTCAGATACGGAACTAAGCGATCAGTCAGCCGCTGCTGTGCATTCGTGTGCTTTGTGTGGCCTGAGCACAATACGTCTTGCCCAACTCCTGAAGCATCAGCAGAATCATCACAGTGAGGTGATTGACACATTGCCTCATGTGTGCGACAAGTGTGGATTGGGATTTGTAGCTGAATTGCTGCTTCAGCAGCATCGTCGACGCATCTGTGCGAAGCGGCATGCAAAGTATCATTGTCAACATTGCAATCTACACTTTATCTGGCAGTCCAACTACGAGCGACACATGGAACTACAGCACGAGGCGGAAGCAGAGACAGATGATGTCTCCGACCTTGTGCCCATCACCAGGCTAAGGAGCAAACGTCAACAAGCGGCTAAATTGCAGTGCAATGAATGTGAAAAGGTCTTCATCTGGCCAAAGGATCTGACGCGTCATAAGCGCATTCATCAGCCGCAGGCATCGGCACAGTACGAATGCAGCTACTGTGAGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCATATGCGTGTTCATGGAGAGTCGCATTTGGATGCGACGGCTATGACCAACAGCGATCCGGATCCGTCGATGCTACAGCGAATGCCAATGGTGTTGACGCAATTGTGCCAACCGAATGGATGCAAACTGATTCAGTGCATGATTTGTCTATCGCAGCACTCGAAGATCTCTGACCTACGCACGCATTTGGAGAAGCACCAGTTTATTGTGGAGTTTGCGGAGGAGCGAGCGAAGCCGGAGAGCATTGTGAGTATTTGTCGGGCCCTATATCCGGAGCAGGTTACTCCTCTGGATAAGCAGCAATTGATTGAACGCATCCAGAGAGATGTGGGTATGGGCACTGAGTTGGAACGATTCATTTCGATTACCAACGAGGCAGCCATTGAGCTGAGCCTTGATAGCagcgaaactgaaactgattcGGACTCAGCCGAGATGGAAAGGATCAGCAGTGGACGACAATACAATTGTGATCTTTGCAAGTTGAAGCTACCGCGTAAATATCAACTCTATGCTCATCAGTTGGAGCAGCATACATGGCAACAGGCCACCCACATTTGCACCCACTGCCAGGCCCGATTCATCAATGACCAGTTGCTGGAGCACCACTATCGAAGTCTCTGTCGCAATGTACACAAGCGTTTCCTTTGTCGGAAGTGCCCATTACGCTTTCGCTGGCGTGACAACCTCAAGCTGCATACAGACGTGGCACATCAGGAAGCCACTGTAGAGCAGACGAGCTTGGGTATCCAATTGAATGGGGCAAGTATTGTTCCTGTTGTCAGCTACGATTGCAGCGAGTGTAATCGCagctttaaaatgcaaaaggaTCTCACACGGCACACGCTGATGCATGCCCAGGAGTCGAGCATTTATCGGTGTCGTTGGTGTGCCCGTCGCTTCTATCGCCAGGCTAATCTCCTGCAGCACATTGAGCGTCATGGCATCAATGCCGCACAGCTACCCTATGCCGAGTCCCTGCTCAATGCCAGCCGTCATCCAAATGGTCAGAAGTGTGTCCAATGCAAGGTGTGTGATATACGCTTTCCCACAATTGCCGCACTGCGTTCCCATTTGGCGTCCATACCGAGCGGGAGTCATCATGAGATTGGATCGATGCTCAACTACTCGATTACCAATCAGCTGGGCTATGAACTGCACTTGGAAGACTCGGAAACGGATGAGGAGACCAAGCCGCCTGGTGTACCCTCACACTACACCTGCGGCATGTGCCAGCTGCGTTGTGTGCGTAAGTATGAGctgcatcagcatcagcaggcCATGCATCGATTGGAACGGATTACTGAGGGCTGTGATCAGTGCATCTTTAAGAGCGTATGCCCGGATCTTATCGCCTATCATCAGCGTGTGCAGTGTTGCAACACGGAGAAGCAATTCAAATGCGACAACTGTGGCTACAAGTTCATGTGGGAGTCGAATCTATTACAGCACATTCAACTTCAGCACCCTGGCAACAAAGATCAGGAGGCGATGGCAGCGGGGCCACCACCGGAAACAGCCGCTGTGGAGTGCCAGATCTTTCAGTGTGGTCAGTGCCCACGCAAATACAATCGCAAGGATCGACTGACGGCCCATGTAAAGAAGTGTCATGCACCAGGTGCAGTTGGTCCTGCTGAGTGTCCAACGAGAACATCAACGTCTTCAAGCGTCGCCAAACAACAGAAAAGTTTTCTCTGCGCCTTTTGCGGCAAGGCGGTGAGCTCCTCCTCTAATCTCATCATACACATACGTCGTCATACTGGCGAGAAGCCCTTCAAATGCGACTATTGCGACATGGCTTTTCCCCGTTCATCCGATCTGCAGTGCCATCGACGCACCCACACTGGCGAACGGCCTCATGTTTGCACCGTGTGCCAAAAAGGATTCGCCCGCTCCTACAAGCTCCAGCAACATATGCGAATCCATAATGGCGAACGTCCCTACAAGTGCACATACTGCGACAAAAGCTTCACCCAGTCCAATGACCTGACACTCCACATAAGGCGACACACCGGCGAGCGACCCTATCAATGTGACACCTGCGGGGAACGTTTCATTCAGGGCACTGCCCTCAAGAATCATCGACTACAGAATGGGCATTACGAGGCAGCGGATGGCCCAGCAAAAGTTAATTAA
Protein Sequence
MQRHARVHFEQACYVCDSCGKGFLRKDKYMFHLRSHEKRQAKRQALQLGNEWRFAERLYSSGRLKRVECKLCGLKCQRIQELREHLSMHVSIETLSNLSANSDVIVEQFTSQSMDLMQIKQQVCEDIAKGRKHLDKYCVVINAHGYELCLSDSDEEIPGMPPPYRCLACNTVFSRKHRLMRHTLEEHTQPKAETTPWQRCNYCHIGFVCVKLLEQHQRTQCHNQLKRYSCPTCPGKFIWRQNLKHHTCSHRTRSSEARDQERSLGRQIQCCLCDEQLESMSTLRAHLVTHCDGVSGIDPERGSTFFRCNYPEGSTCNQTELSTRIASDFAAEDYGRYFNACTDSGQELDFFDSDTELSDQSAAAVHSCALCGLSTIRLAQLLKHQQNHHSEVIDTLPHVCDKCGLGFVAELLLQQHRRRICAKRHAKYHCQHCNLHFIWQSNYERHMELQHEAEAETDDVSDLVPITRLRSKRQQAAKLQCNECEKVFIWPKDLTRHKRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGESHLDATAMTNSDPDPSMLQRMPMVLTQLCQPNGCKLIQCMICLSQHSKISDLRTHLEKHQFIVEFAEERAKPESIVSICRALYPEQVTPLDKQQLIERIQRDVGMGTELERFISITNEAAIELSLDSSETETDSDSAEMERISSGRQYNCDLCKLKLPRKYQLYAHQLEQHTWQQATHICTHCQARFINDQLLEHHYRSLCRNVHKRFLCRKCPLRFRWRDNLKLHTDVAHQEATVEQTSLGIQLNGASIVPVVSYDCSECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINAAQLPYAESLLNASRHPNGQKCVQCKVCDIRFPTIAALRSHLASIPSGSHHEIGSMLNYSITNQLGYELHLEDSETDEETKPPGVPSHYTCGMCQLRCVRKYELHQHQQAMHRLERITEGCDQCIFKSVCPDLIAYHQRVQCCNTEKQFKCDNCGYKFMWESNLLQHIQLQHPGNKDQEAMAAGPPPETAAVECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVGPAECPTRTSTSSSVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQNGHYEAADGPAKVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00558059;
90% Identity
iTF_00575740;
80% Identity
-