Basic Information

Insect: Drosophila persimilis
Gene Symbol: -
Assembly: GCA_003286085.2
Location: NW:23500947-23539236[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.054 3 8.1 0.6 1 23 1273 1296 1273 1296 0.94

2 8 0.01 0.58 10.4 0.1 1 23 1301 1324 1301 1324 0.98

3 8 0.0099 0.56 10.4 2.2 1 23 1517 1540 1517 1540 0.94

4 8 0.00047 0.026 14.6 2.1 1 23 1548 1570 1548 1570 0.98

5 8 5.2e-05 0.0029 17.6 0.8 1 23 1577 1600 1577 1600 0.97

6 8 5.6e-05 0.0032 17.5 1.4 1 23 1606 1628 1606 1628 0.96

7 8 3.6e-06 0.0002 21.3 1.1 1 23 1633 1655 1633 1655 0.99

8 8 0.019 1.1 9.5 3.0 1 23 1661 1683 1661 1683 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.054	3	8.1	0.6	1	23	1273	1296	1273	1296	0.94
2	8	0.01	0.58	10.4	0.1	1	23	1301	1324	1301	1324	0.98
3	8	0.0099	0.56	10.4	2.2	1	23	1517	1540	1517	1540	0.94
4	8	0.00047	0.026	14.6	2.1	1	23	1548	1570	1548	1570	0.98
5	8	5.2e-05	0.0029	17.6	0.8	1	23	1577	1600	1577	1600	0.97
6	8	5.6e-05	0.0032	17.5	1.4	1	23	1606	1628	1606	1628	0.96
7	8	3.6e-06	0.0002	21.3	1.1	1	23	1633	1655	1633	1655	0.99
8	8	0.019	1.1	9.5	3.0	1	23	1661	1683	1661	1683	0.99

Sequence Information

Coding Sequence: ATGAGTGCCAACGCCAACATCAGCAGAACCAGGAGACGCAGCAATAGCTGGTCGTCGGAAAAGCAACCGCAGCAGCCGGCGGCGCAACTTTCTCTGCCGGAAGACGATGACGTCGCAGGTGGTTTGCTGGAAATGCCGCGCAtatgccgttgctgctgcaaaCGGGATCTGGAGCTGCTTAGCCTCTTTGGGGCCGACAAACCAACCATATCCTCCCCAGAAACGacggaaacagaaacagccaacgccacagtcacagtcacagccacagccacagccacgtCTAAGATGCGACGCCGCGAGACCACCACAGCAGCCCTGGGTGATCGCACCAACGGCAATCCCGTGGACTACGCCCTGAGCGGTGCCCACAGCAGCATGGACATTGTCCTCGAGGAGATGATCATCTGGATGCTCAATGTCAGCCGCGACGATGGACTGCCGCAGGAGATCTGCCGCCAGTGCATGGCCCAGTTCCTGATGGTGGCCAAATTTCGAAGGAAATGCGTGCGGATGCAGCAGCGCCTGCAGGACTACGCCCAGGAGATATCCGACCGGCAGGCCGCCAGACAGGCCAAGCGaaaacagaagcagcaacaaaggcaagcacagcagcaggagcagacCAGGGAAGAGGAGGCGAAGGATATGGACACGGATGCGAATTCGTCGGACTACATGCATTTGCCGGAGTCACAGATGGAGCGGAAGCGTCGCATCATCTCTGAATCGGAGGGTGAATCCCTATCCCCTCGATCGTCGCGGCCCAAAATCGTAAAGACGGAGCAGCCCGCCACGGAGGAGGTCCTGCCCCCGCCCAAGGAGCGTCGCCTGCAGCTGAGACTGCGCAGAATGCGGACACAGTCCGCGGGAACTCCGGAAGCGGCTACCAATGCGAATGTGAATGCCGTTCCCGATCCAGTGGAACGACCAGCGACCCACGCTGATCCCAGCAGCATGCCCTGGAAGACAAAGGCTGCCAGGAAGCAGCTGTCCGAGTCGTGGTCCAGCTACTCGCCGGCCCCCTCCTCGGAGATTGAGGGCCGAAGGAGCACCAGCAGTGAGGCGGCCACAGAGCATCTGAGCGATCTGTCGGTGGGGCCACTCTGCGGCTTCGAGAGCGACAGCAGTCCCTCCTCCACCTCAGCGCCATCGATCCTCAAGTTCCCCCGACGATCGCCCACAGCGGTGCCCGCACTGCGACGTGGCCGTCGACCCCGGAGTTCGCCCGTTTACATGCCCGTCAAGCGGCAGCGGCGATCCGTGGGCAACAAGTCGATGGGGAAGGAACTGCTCCATCAGATTGGAGCTGAGTCCGGTCCGGAGCAGAGCACAAAGTCTGATGAGGAAATCTCAGGCCAAGATCCAAGGGAACAGCAGCCCGAGATTGATGAGAACTGTCCAACTCCGCTGCGTCTAGTGGAAGCGTCTTCCTCCTGCGGCGAGGCGAGCGACATCAGTACTTcagatgcggatgcggatgcggacgTGGCAGGAGAATCATCCTACGCGGAGGTCGTAAAAGAACTCCAAGGCAAGGATGGAACCAGCGGCGATGAAGGGATACGGGAGAACCCAGTATCGGCAGTATCGATCAAGGAGTTGTCGTCATCGAGTGATGCCTCGGACGAGAGCACCCTAAAAAATGAGGAGGAGACTCCGTCCCATCAACAGATTGAAGGAGAACCAAAGTTGAATGGAGCCGTCACGGCCAGTCCAGCTTCGATGGAGGTTCAGTCGAAGGAACTGACCTCGTCCACAGAGGTCACAGCCCCGGCCACGGctactgccacagccacagtcagtgaggaggagcaggaatCTCCGGATGGAGCAGGACAGTTCGAGCAGCCAGAGATCATTGTGAGCATACCCCTCGAGGCACTCAACGAGGATCTGCAGCGCAGACTGTGCGTGGACCAGGAGCAGGACAACGacgagggggaggaggaggaggacaagGATCCGGagaagaaggagcagcaggacCCTGACCACCCCGACGACGTCAACAACAATGCCAACGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCAAACAAACGAAATTGAAGCAAACGCAGGCCGCCCCCCCGATGGGGCGCCActaccaccaccagcagcggATGGGGACGAGGACTCGCTCTCGTCCTCGGATGAGCTGCCAGTGGTACGGACTGGACCCACGCCCATGGACTTTCTGGCCGAATTCGAGAAGCATTGCGAGAAGGGTCTCGAGCAGATCGGGGCCACGACACCGGCCCCATCGCCGCCGCCCACGCCCAGAGCCGAGCCCCTGCCGCTGGCCCTCAACGACCTGGAGGCCAAGCAGCAGCTCGAGGTGGAGATGAACGACGTGGAGACCACGCTGAACGGCATCCTCAACGAGAtgcaggaccagcacatgtACACACCGACCTGTCCGCACATCGACGAGTTCCTCACCCCCGCCGACTATGCCTCCCTCAGCGaccccgagcccgagcccgagcaggagcaggagtcCTCCCGCGACTGCAGccctgtggcagtggcagtggcagccacgGAGGATAACGTATCGCCGCTGCGGGAGAAACCAGGGGCCAGGCAGCAGGAGGATCTCTTCGATAACAGCAACTTCAGCAACGAACTGATTGGCTTCCAGAATGACATACCCTGCTTTGAGAACATCGAGGCCTCGCCAGAGCCCGACCAGAGTCTGCATCTGGAGCTGACGCAGTTCCTCAACGAACTGCAGCCTCAGCAGGGATCACAGGCAACGCAGGTGTCGCCTGGGGCCCAGGTTCAGGTGCAGGTGGCGGCACCTCAGGTCGaggcagtcgcagtcgcagtccccCCTAAGGTGCAGCATCTGGTGGAGCCGCCTCTGGTCGAGCAACAGCCTCAGGCGGAGCCTCAGGTTCAGGTGCAGGTGCAGCAACCACCTCTAGAGCATATTCATGTCCGTCAGCAGCCAACAGTCGCAAAAGCTCTGGAGCAGCCTCAGCTGGTCCAGGTGCCTCAGGTGCATCACCAGGAGACGACAACGACCGTTTCCTACGAGCAGATCTATCACCATCATCACCAGCAGTCGGCCAGCAAGCTGCAACTGATGCCAGCTCACATCGatacgcagcagcagcagcagcagcagcaatggcAGCAGTATCAGtcccaggagcagcagcagcacacgaCACATCTGCAGTGGTCAGCAGTGGGCGGACTGGAGGCCATCAAGGGCAGCTTTGGTCCATCGGAGAGCACCACAACGTACTACATCAGTGCCGGGGATCTctaccagcaccagcagcaggctGCGCCACTGGAGACCACCTACACGATGCTAGATCCCAACGAGAACTACATGCTCGAGCAGGCCacccatcagcagcagcagcagctgcagcagatccatcatcagcaacagcagcagcaacagcaggcgcagcagcaccagcagcagcagcaacagcagcccaTCATGATACTGATCcagcagccggagctgcagcAGCCAGTGGCCTCGGCCAGTAATCCCCAGCAGGCGCCGTTGCATTTTTACGGTGCGCCCATCAGCAACGAGTTGCACCAtctccagcaacagcagcagcaacaacagcatcaacagcagcagcatcaagtACAAAATCAGTCAGTATTAGCAGCAGCCTCTCCAATGCCTGCCACCACGCCCAAGGGCCGTGCAGTGTCGCTCAAGTGCCGCTTCTGCCAGAACGGACCGAGGTTCTCCAACAGCCTGGAGTACAGTCGTCACATCATCGAGCTGCATCCGGCGGTGGCGCCATTCAACTGCCCGCACTGTCCGCTGGCGTTTGCGGCGCGCAGCAAGCGCTCGCAGCACATCCTCAACCAGCACGTGGTGCAGCAGTACCAGTGCGGCCAGTGCTCGCAGGTGTTTCCCGCCCAGCGAGCCCTGGActtgcacatccagcgcttCCACATGCAGATCACCAGCAACACGGGCGGCGCAGAGAAGGGCGCAGGTGTGCGCGTGGAGGAGGTTCAACTGCAGATCAGCAAcgagcaccagcagcagcactcacCGCATCCAAAAGCTCTCGAGCTGCACGGCAACACGCCACGACGACGCAGGCAGCGCATTCTCTGCTGTCCGGACTGCGAGGACTGCACCTCTGGCCACAGTCACGGCCATGGACAGGGACAGTACGAGGAGCTGCAGACCAATCTGCAGGCACCGCCAACGGCCCTAACGCCGCCCTCGACGATCATGTCGGTGCCGTCGCCGCAGCCCCTGACGAGCACACATCAGCACATAACCCTGCCCTCGCCAGAGCAGTCGGAGCCGGACTCCACCACGACGCTGCGGCAGTTCCGCAAACGAGGCGTCATTGTGGGGCCGCAATCTGCGGGGGCCTTCAGCCAGTCGCTGCAGTTGGCCACTCCCGTGGCCTCGCCCTCACCCTCGCCCTCGTCGTCGCCGTCCTCTTCCACGATAGACTCGGCTCCAAACACgcccgcctccgcctccgtgCAGGTCAGCGAACTGCGGACCAGCCACCAGTGCCTGTACTGCGAGGAGCGGTTCACCAACGACATTGCCCTGCGGAAGCACCACCTGCTGGCCCACGGGGCCCAGACCTCGATGCCCTTCGTGTGCACCATCTGCAAGCGGGGCTATCGGATGCGGACGGCCCTGCACCGGCACATGGAGTCGCACGATGTGGAGGGCAGGCCGTACGAGTGCAACCTGTGCCATGTGCGGTTCCCGCGACCCTCGCAGCTGACGCTGCACAAGATCACCGTCCATCTGCTGTCGAAGCCGCACACCTGCGACGAGTGTGGCAAACAATTTGGTACGGAGAGCGCCCTAAAGACGCACGTTAAGTTTCACGGTGAGCTCGGTTACCAGTGCGACGAGTGCGATCAGGCATTCGAGTATCTCAGAGATTTGCGCAAGCACCGGCGCACCCACAACAGCGAACTGTTTTACAAGTGCGAGTTCTGTCCACGCTCCTTCTTGCATTTCATGGGCTTCCGCGCTCACATGAACTCCCATCTGCCGCTTGGAGTGTTCCTGAACGAGGAGACCGCACTGAAGTCGGCGTCCAActgcagcaccaccagcatcatcagcagcgTCCGCAATGACAAGTCCAGCGAGAATCCAGCCACACCCATCATGGAGGAGACACCGCTGACCCCGATGAGCAATATCAATAACAATTCAGACGAATGCTGCCCGATCTCCAATTCGGCGGAGAGCAGTGCTTTGGCTGGACGTAGTCTTCCTAGCCTAGATTCGATTGCCACAACGCCATAA
Protein Sequence: MSANANISRTRRRSNSWSSEKQPQQPAAQLSLPEDDDVAGGLLEMPRICRCCCKRDLELLSLFGADKPTISSPETTETETANATVTVTATATATSKMRRRETTTAALGDRTNGNPVDYALSGAHSSMDIVLEEMIIWMLNVSRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDYAQEISDRQAARQAKRKQKQQQRQAQQQEQTREEEAKDMDTDANSSDYMHLPESQMERKRRIISESEGESLSPRSSRPKIVKTEQPATEEVLPPPKERRLQLRLRRMRTQSAGTPEAATNANVNAVPDPVERPATHADPSSMPWKTKAARKQLSESWSSYSPAPSSEIEGRRSTSSEAATEHLSDLSVGPLCGFESDSSPSSTSAPSILKFPRRSPTAVPALRRGRRPRSSPVYMPVKRQRRSVGNKSMGKELLHQIGAESGPEQSTKSDEEISGQDPREQQPEIDENCPTPLRLVEASSSCGEASDISTSDADADADVAGESSYAEVVKELQGKDGTSGDEGIRENPVSAVSIKELSSSSDASDESTLKNEEETPSHQQIEGEPKLNGAVTASPASMEVQSKELTSSTEVTAPATATATATVSEEEQESPDGAGQFEQPEIIVSIPLEALNEDLQRRLCVDQEQDNDEGEEEEDKDPEKKEQQDPDHPDDVNNNANDENFCQSATADSFNSAVALQTNEIEANAGRPPDGAPLPPPAADGDEDSLSSSDELPVVRTGPTPMDFLAEFEKHCEKGLEQIGATTPAPSPPPTPRAEPLPLALNDLEAKQQLEVEMNDVETTLNGILNEMQDQHMYTPTCPHIDEFLTPADYASLSDPEPEPEQEQESSRDCSPVAVAVAATEDNVSPLREKPGARQQEDLFDNSNFSNELIGFQNDIPCFENIEASPEPDQSLHLELTQFLNELQPQQGSQATQVSPGAQVQVQVAAPQVEAVAVAVPPKVQHLVEPPLVEQQPQAEPQVQVQVQQPPLEHIHVRQQPTVAKALEQPQLVQVPQVHHQETTTTVSYEQIYHHHHQQSASKLQLMPAHIDTQQQQQQQQWQQYQSQEQQQHTTHLQWSAVGGLEAIKGSFGPSESTTTYYISAGDLYQHQQQAAPLETTYTMLDPNENYMLEQATHQQQQQLQQIHHQQQQQQQQAQQHQQQQQQQPIMILIQQPELQQPVASASNPQQAPLHFYGAPISNELHHLQQQQQQQQHQQQQHQVQNQSVLAAASPMPATTPKGRAVSLKCRFCQNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPLAFAARSKRSQHILNQHVVQQYQCGQCSQVFPAQRALDLHIQRFHMQITSNTGGAEKGAGVRVEEVQLQISNEHQQQHSPHPKALELHGNTPRRRRQRILCCPDCEDCTSGHSHGHGQGQYEELQTNLQAPPTALTPPSTIMSVPSPQPLTSTHQHITLPSPEQSEPDSTTTLRQFRKRGVIVGPQSAGAFSQSLQLATPVASPSPSPSSSPSSSTIDSAPNTPASASVQVSELRTSHQCLYCEERFTNDIALRKHHLLAHGAQTSMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNLCHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGELGYQCDECDQAFEYLRDLRKHRRTHNSELFYKCEFCPRSFLHFMGFRAHMNSHLPLGVFLNEETALKSASNCSTTSIISSVRNDKSSENPATPIMEETPLTPMSNINNNSDECCPISNSAESSALAGRSLPSLDSIATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536312;
90% Identity: iTF_00581065;
80% Identity: -