Basic Information

Gene Symbol
-
Assembly
GCA_008121275.1
Location
CM017777.1:8524187-8530249[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.038 2.8 8.4 0.6 1 23 967 990 967 990 0.94
2 8 0.0073 0.54 10.7 0.1 1 23 995 1018 995 1018 0.98
3 8 0.0059 0.44 11.0 2.6 1 23 1211 1234 1211 1234 0.95
4 8 0.00033 0.025 14.9 2.1 1 23 1242 1264 1242 1264 0.98
5 8 3.7e-05 0.0028 17.9 0.8 1 23 1271 1294 1271 1294 0.97
6 8 4e-05 0.003 17.8 1.4 1 23 1300 1322 1300 1322 0.96
7 8 2.5e-06 0.00019 21.6 1.1 1 23 1327 1349 1327 1349 0.99
8 8 0.014 1 9.8 3.0 1 23 1355 1377 1355 1377 0.99

Sequence Information

Coding Sequence
ATGGCCCAGTTCCTGATGGTGGCCAAATTTCGAAGGAAATGTGTGCGGATGCAGCAGCGTTTGCAGGACTATGCCCAGGAAATATCcgacaggcaggcagccagacAGGCCAAGCGaaaacagaagcagcaacaaaggcaggaactgcagcaggagcagaccAAGGAAGAGGAAGCGAAGGATATGGACACGGATGCGAATTCGTCGGACTACATGCATTTGCCAGAGTCACAGATGGAGCGAAAGCGTCGCATAATCTCTGAATCGGAGGGTGAATCCCTATCCCCTCGACCGTCACGGCCGAAAATCGTAAAGACGGAGGAGGCCGCCACAGAGGAGGTCCTGCCCCCGCCCAAGGAGCGTCGCCTGCAGCTGAGATTGCGCAGAATGCGGACACAGTCCGCAGGAACTCCGGCAGCGGCTACCAATGCGATTGCGAATGCCGATGcggatgcgaatgcgaatgccgTTGCAGCAGAACGACCAGCGGCCCACGCTGATCCCAGCAGCATGCCCTGGAAGACAAAGGCTGCGAGGAAGCAGCTGTCCGAGTCGTGGTCAAGCTACTCGCCGGCCCCCTCCTCGGAGATAGAGGGCCGAAGGAGTACCAGCAGTGAGGCGGCCACAGAACATCTGAGCGATCTGTCCGTGGGGCCACTCTGTGGCTTCGAGAGCGACAGCAGTCCCTCCTCCACCTCAGCGCCATCGAAACTCAAGTTCCCCAGACGATCGCCCGAAGCGGTGCCCGCACTGCGACGTGGCCGTCGACCACGGAGTTCGCCCGTTTACATGCCCGTCAAGCGGCAACGGCGATCCGTGAGCAATAAGTCGATGGTGAAGGAACATCTCCATCAGATTGGAGCTGAATCCGGTCCGGAGGAGAGCACAAAGTCTGATGAGGAAATCTCCTGCCAAAATCCAAAGGAACAGCAGTCCGAAATTGATGAGAACTGTCCAACTCCGCTGCGTCCAGTGGAAGCGTCTTCCTCCTGCGGTGAGGCAAGCGACATCAGTACTTCAGATGCGGATGCTGACGTGGCAGGAGAATTATCCCACGCTGAGGTCTTAAAAGAAATCCAAGGCAAGGATGGCAAGGAGTCGTTAACTGAATTGGATACCAGCGGCGATGGAGGGATAACGGAGAACCCAGAGGCAGTATCGATCAAGGAGTTGTCGTCATCGAGTGATTCTTCGGACGAGAGCACCCTAAAAAATGAGGAAGAGACTCCGTCCAATCAACAGATTGAAGAAGAACCAACGTTGAATGGAGCAGTCACGGCCAGTCCAGCTTCGATGGAGCTTCAGTCGAAGGAACTGACCTCGTCCACAGAGGTCACAGCCACGGCTACAGCCACACCCATAGCCAGTGAGGAGGAGCAGGAATCTCCGGATGGAGCAGGACAGTCAGAGCAGCCAGAGATCATTGTGAGCATACCCCTCGAGGTACTCAATGAGGATCTGCAGCGCAGACTGTGCGtggaccaggagcaggacaacgaggaggaggaggataaGGATCCGGagaagaaggagcagcaggaccCTGGCCATCCCGACGATGTCAACAACAATGCCAACGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCAAACAAACGAAATTGAAGCAAACGCAGGCCGCCCCCCCGATGGGGCGCCACTACTACCACCACTAGCAGATGGGGACGAGGACTCCCTCTCGTCCTTGGATGAGGTGCCAGTGGTAAGGACTGGACCCACACCCATGGACTTTCTGGCCGAATTCGAGAAGCATTGTGAGAAGGGTCTCGAGCAGATCGGGGCCACAACACCGGCCCCATCGCCGCCACCCACGCCTAGAGCCGAGCCCCTGCCGCTGGCCCTCAACGATCTGGAGGCCAAGCAGCAGCTCGAGGTGGAGATGAACGATGTGGAGACCACGCTGAATGGCATCCTCAACGAGATGCAGGACCAGCACATGTACACACCGACCTGTCCGCACATCGACGAGTTCCTCACCCCCGCCGACTATGCCTCCCTCAgcgaacaggagcaggagcaggagtccTCCAGCGACTGCAGCCCTGTCGCAGTGGCAGCCCCAGAGGCATCGCCGTTGCGGGAGAAACCAAATGATATTCCCTGCTTTGAGAACATCGAGGCCACGCCAGAGCCCGAGCAGAGTCTGCATCTGGAGTTAACGCAGTTCCTCAACGAACTGCAGCCACAGCAGGGACCACAGCCAACGCAGGTGTCGCCGGGGGCTCAGGTGCAGGTGCAAGTGCAGGTTGCGGTACCTCAGGTTGaggcagtcgcagtcgcagcccCCCCTAAGGTGCAGCATCAGGTGGAGCCGCCTCTGGTTGAGCAACAGCCTCAGGCGGAGCCTCAGGTTCACGTTCGGGTGCAGCAACCACCTCTAGAGCATATTCATGTCCGTCAGCAGCCAATAGTCGCAAAAGCTCTAGAGCAGCCTCAGCTGGTCCAGGTGCCTCAGGTGCATCACCAGGAGACGACAACGACCGTTTCCTACGAGCAGAtctatcatcatcatcagcagcattCTGTCCAGCAGTCGGCCAGCAAGCTGCAACTGATGCCAGCTCCCATCgatccacagcagcagcagcaacaatggcaGCAGTATCAGccccaggagcagcagcagcagacgacACATCTGCAGTGGTCAGCAGTGGGCGGACTGGAGGCCATCAAGGGCGGCGTTGGTCCATTGGAAAGCACGACAACGTACTACATCAGTGCTGGGGATCTctaccagcaccagcagcaggTGTCGCTCAAGTGCCGCTTCTGCCAGAACGGACCGAGATTCTCCAACAGCCTGGAGTACAGTCGACACATCATCGAGCTGCATCCGGCTGTGGCGCCATTCAACTGCCCGCACTGTCCGCTGGCGTTTGCGGCGCGCAGCAAGCGATCGCAGCACATCCTCAACCAGCACGTGGTGCAGCAGTATCAGTGCGGTCAGTGCTCGCAGGTGTTTCCCGCCCAGCGAGCCCTGGACTTGCACATCCAGCGCTTCCACATGCAGATTACCAGCAAGACAGGAGGCGCAGAAAAGGGAGGAGGTGTGCGCGTGGAGGAGGTTCAGTTGCAGATCAGCAacgagcatcagcagcaacactCACCGCATCCAAAAGCTCTCGAGCTGCACGGCAACACGCCAGGACCACGCAGGCAGCGCATTCTCTGCTGTCCGGACTGCGAGGACTGCACCTCTGGCCACAGTCACGGCCATGGACAGTACGAGGAGCTGCAGACCACTCTGCAGGCACCGCCAACGGCGCTAACGCCGCCCTCGACGATTATGTCGGTGCCGTCCCCGCAGCCCCTGACGAGCTTACATCAGCACATAACCCTGCCCTCTCCAGAGCAATCGGAGCCGGACTCCACCACGACGCTGCGGCAGTTCCGCAAACGAGGCGTCATTGTGGGGCCGCAATCAGCCGGGGCCTTCAGTCAGTCGCTGCAGTTGGCCACTCCCGTGGCATCGCCCTCACCCTCGCCCTCGTCGTCGCCGTCCTCTTCCACGATAGACTCGGCGCCAAACACACCCGcatccgcctccgcctccgtgCAGGTCAGCGAACTGCGGACCAGCCACCAGTGCCTGTACTGCGAGGAGCGGTTCACCAACGACATTGCCCTGCGGAAGCACCACCAGCTGGCCCACGGGGCCCAGACCTCGATGCCCTTCGTGTGCACCATCTGCAAGCGGGGCTATCGGATGCGGACGGCCCTGCATCGGCACATGGAGTCGCACGATGTGGAGGGCAGGCCGTACGAGTGCAACCTGTGCCATGTGCGGTTCCCCCGACCCTCGCAGCTGACGCTGCACAAGATCACCGTCCATCTGCTTTCGAAGCCGCACACCTGCGACGAGTGTGGCAAACAATTTGGTACGGAGAGCGCCCTAAAGACGCACGTTAAGTTTCACGGTGAGCTTGGTTACCAGTGCGACGAGTGCGATCAGGCATTCGAGTATCTCAGAGATTTGCGCAAGCACCGGCGCACCCACAACAGCGAACTGTTTTACAAATGCGAGTTCTGTCCACGCTCCTTCTTGCATTTTATGGGTTTCCGCGCTCACATGAACTCCCATCTGCCACTTGGAGTATTTCTGAACGAGGAGACTGCCCTGAAGTCGTCGTCCAActgcagcaccaccagcatcagcatcgtccGCAATGACAAGTCCAGCGAGAATCCAGCCACACCCATCATGGAGGAGACACCGCTAACCCCGATGAGCAATATCAATACCAATTCAGATGAATGCTGTCCAATCTCCAATTCGGCGGAGGGCAGTGCTTTGGCAGGACGTAGCCTCCCTAGCCTAGATTCGATTGCCACAACGCCATAA
Protein Sequence
MAQFLMVAKFRRKCVRMQQRLQDYAQEISDRQAARQAKRKQKQQQRQELQQEQTKEEEAKDMDTDANSSDYMHLPESQMERKRRIISESEGESLSPRPSRPKIVKTEEAATEEVLPPPKERRLQLRLRRMRTQSAGTPAAATNAIANADADANANAVAAERPAAHADPSSMPWKTKAARKQLSESWSSYSPAPSSEIEGRRSTSSEAATEHLSDLSVGPLCGFESDSSPSSTSAPSKLKFPRRSPEAVPALRRGRRPRSSPVYMPVKRQRRSVSNKSMVKEHLHQIGAESGPEESTKSDEEISCQNPKEQQSEIDENCPTPLRPVEASSSCGEASDISTSDADADVAGELSHAEVLKEIQGKDGKESLTELDTSGDGGITENPEAVSIKELSSSSDSSDESTLKNEEETPSNQQIEEEPTLNGAVTASPASMELQSKELTSSTEVTATATATPIASEEEQESPDGAGQSEQPEIIVSIPLEVLNEDLQRRLCVDQEQDNEEEEDKDPEKKEQQDPGHPDDVNNNANDENFCQSATADSFNSAVALQTNEIEANAGRPPDGAPLLPPLADGDEDSLSSLDEVPVVRTGPTPMDFLAEFEKHCEKGLEQIGATTPAPSPPPTPRAEPLPLALNDLEAKQQLEVEMNDVETTLNGILNEMQDQHMYTPTCPHIDEFLTPADYASLSEQEQEQESSSDCSPVAVAAPEASPLREKPNDIPCFENIEATPEPEQSLHLELTQFLNELQPQQGPQPTQVSPGAQVQVQVQVAVPQVEAVAVAAPPKVQHQVEPPLVEQQPQAEPQVHVRVQQPPLEHIHVRQQPIVAKALEQPQLVQVPQVHHQETTTTVSYEQIYHHHQQHSVQQSASKLQLMPAPIDPQQQQQQWQQYQPQEQQQQTTHLQWSAVGGLEAIKGGVGPLESTTTYYISAGDLYQHQQQVSLKCRFCQNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPLAFAARSKRSQHILNQHVVQQYQCGQCSQVFPAQRALDLHIQRFHMQITSKTGGAEKGGGVRVEEVQLQISNEHQQQHSPHPKALELHGNTPGPRRQRILCCPDCEDCTSGHSHGHGQYEELQTTLQAPPTALTPPSTIMSVPSPQPLTSLHQHITLPSPEQSEPDSTTTLRQFRKRGVIVGPQSAGAFSQSLQLATPVASPSPSPSSSPSSSTIDSAPNTPASASASVQVSELRTSHQCLYCEERFTNDIALRKHHQLAHGAQTSMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNLCHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGELGYQCDECDQAFEYLRDLRKHRRTHNSELFYKCEFCPRSFLHFMGFRAHMNSHLPLGVFLNEETALKSSSNCSTTSISIVRNDKSSENPATPIMEETPLTPMSNINTNSDECCPISNSAEGSALAGRSLPSLDSIATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00581065; iTF_00575127;
90% Identity
-
80% Identity
-