Basic Information

Insect: Drosophila persimilis
Gene Symbol: zfh1
Assembly: GCA_003286085.2
Location: NW:12924093-12929670[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.4e-05 0.00081 19.4 1.8 1 23 145 167 145 167 0.97

2 15 0.0031 0.18 12.0 1.7 3 23 175 195 173 195 0.94

3 15 0.0002 0.011 15.8 0.4 1 23 339 361 339 361 0.98

4 15 0.00037 0.021 14.9 0.6 1 23 367 389 367 389 0.98

5 15 0.0039 0.22 11.7 6.8 1 21 419 439 419 441 0.93

6 15 5.7e-05 0.0032 17.5 2.6 1 23 479 501 479 501 0.96

7 15 0.035 2 8.7 1.2 1 23 507 530 507 530 0.96

8 15 0.026 1.4 9.1 0.4 3 19 539 555 538 556 0.95

9 15 0.00015 0.0086 16.2 5.6 1 23 565 587 565 587 0.97

10 15 0.045 2.6 8.4 0.4 2 23 593 614 592 614 0.96

11 15 4.8e-05 0.0027 17.7 0.2 1 23 623 645 623 645 0.98

12 15 0.001 0.057 13.6 0.1 3 23 653 673 651 673 0.97

13 15 5.4e-05 0.0031 17.6 0.5 1 23 679 701 679 702 0.95

14 15 0.0017 0.095 12.9 0.4 1 23 712 734 712 734 0.98

15 15 0.0055 0.31 11.3 0.2 1 23 1264 1286 1264 1286 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.4e-05	0.00081	19.4	1.8	1	23	145	167	145	167	0.97
2	15	0.0031	0.18	12.0	1.7	3	23	175	195	173	195	0.94
3	15	0.0002	0.011	15.8	0.4	1	23	339	361	339	361	0.98
4	15	0.00037	0.021	14.9	0.6	1	23	367	389	367	389	0.98
5	15	0.0039	0.22	11.7	6.8	1	21	419	439	419	441	0.93
6	15	5.7e-05	0.0032	17.5	2.6	1	23	479	501	479	501	0.96
7	15	0.035	2	8.7	1.2	1	23	507	530	507	530	0.96
8	15	0.026	1.4	9.1	0.4	3	19	539	555	538	556	0.95
9	15	0.00015	0.0086	16.2	5.6	1	23	565	587	565	587	0.97
10	15	0.045	2.6	8.4	0.4	2	23	593	614	592	614	0.96
11	15	4.8e-05	0.0027	17.7	0.2	1	23	623	645	623	645	0.98
12	15	0.001	0.057	13.6	0.1	3	23	653	673	651	673	0.97
13	15	5.4e-05	0.0031	17.6	0.5	1	23	679	701	679	702	0.95
14	15	0.0017	0.095	12.9	0.4	1	23	712	734	712	734	0.98
15	15	0.0055	0.31	11.3	0.2	1	23	1264	1286	1264	1286	0.97

Sequence Information

Coding Sequence: ATGAACCACCAGAACTATGGCGGCATCCAATGGATACAGCAACACCCCGCCGCATCCGACTCCGGGGTGGACATACTGGTGGGGGACGGTGTGACGCCGGACGGGTATCATCTCGTGACCGATGAAGCGACGGGCGAGGATCTTGACCATATGGCGGCCGAGAATCTCATATTTATGGCCCGCGACGGCCAGCTGAGTGAGATCATAGCTGGCGGAAACGCTGTGATAGTCACTGCCGATGGCCACGGCGTGACGTACGCCGATTCCTTTGACGATGACGCCCAGGTGGTGACCGAGGAGGTCATCACGGACGACTGGGTGCAGCATCAGGGAGCCGAGCGTGTGGAAATAGCCGCGGAGCAAATAGCTGGAAATGGAAGCTCGCAAGAGCTGCTGGACATGGAGCAGGACGAGTACACGGCCCTACGACCATATCCCTGTGACTTTTGCAGCCGCCGCTTTAAGAAGAAGTCCAGCCTGAACACCCACATGCTGGCCCACCAAAACGATCGTCCTCATCTTTGCAAGCTGTGCGGGTCACGCTTCTCTCGCCGCGCCGAGCTCATCAGTCATTTCAAGGCGCACGCGGAAGCTCAGGATGCAGCGGATGCCGAGGCAGCTGCGGCCACATCCATTAAATTCGAGCACCGCCCAATGGACGATCATTACTATGAGCACGAGTGGCCTTTATACCAGCAGGATCAGGACGCCGAGGACCAGCAGCAGTTGGTGTCCAGCAGCGAAACTCAACTTGTGCACCAGAATAGCTACAATGTTGCCGCAGTTACCGTCGATGCTCCAGTGCCGACGCGAGGACGGATCAGTCGCCTGAAGCCAAAGGAGGAAGCCACACAGTACATTGCGATTTCCGACAAAACGGAAGCACCCGAGATGCAGGACTATATGCAAAGCGAGCCAATGCAGGCGGTGGTCACTACCTCGACAGCGATCGAGCCCCCACCTAAAGCTGACCTTCCCCAGCCGAACTATCCAGTGCTGGACGACAGCAAGCCGTTCGTGTGTCAGCAGTGCGGCTTGGCCTTTGCCAGGGAGAAGGCGCTCTTCTCTCACACGAAGAACCATCGCGTGGACTCGCCCTTCGAGTGCAACCAGTGTCAGGAGATGTTCTGGGATAACAGCAGCTTGCTGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCTGAGTACGATCCGGCATCGGGCGACGACAGTGTCAGCGAGTCGGAACCGGATCAGCTCTATGGCGACTTTTACTGCAGCGAATGCGGCATTTGCTTTCACAGGCAGGACCTGCTGCGACGCCATGCGAAGTGCCATTTCCAGCAGCCAGACGCAAGTAACTTTGACCAAAAGCCGATTGTGGGAGAAGTGGGAGTCACCGACGAAGTGATAGCTGGAGATGCTGAAAATGCCAAAGATGATGCTGCCCACCGGTGTCACACGTGCGGCAAGTGTTTTCCCAATTCAGTTGCGTTGAGCGCCCATGCCGAAATCCACGCCCGTTTTCCGCTCTTCAAGTGCGTCTTGTGCGGTGTTAGCTTCTATGAAGAGCAGGCCATCAAGCGGCACTTGCACAGTCGTCATCCGAACGAGCTGAAGGCCAACTCGTGTGTGCTGTGTGGAAAGGAGTGTCGCGATCGGAAGGCTCTCATCAAGCATGCCTGGGACCACTCGAGGGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCATAACAAGGCGCGTCTGAAGCGTCACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGTGAGGTCTGTCAGGAGGAATTCCCCGACGGACGGACGCTATCCAATCACCGCCACTCCCACAGCACCACCTCGCCGGGCAAACTCTTCCCGTGCCTGGAGTGTGGCAAGACCTTCGGTTCGCGCAGCTCTCAGCAGATTCACGTACGCATCCACACGGGCGAGCGTCCGTACGGCTGTCGCTACTGCTGGAAGGCCTTTGCCGACGGCGGCACTTTGCGCAAACACGAGCGCATCCACACGGGCGAGAAACCCTACGCCTGCTCCGTATGTCCGCGTGCCTTTAACCAGCGAGTGGTGCTCCGCGAGCACATTCGCTCCCATCACTCCGGTATGGATGTAACGCTTGGCACTTACCACTGCGAAGTGTGCTCCGAGGACTTGTCCTCGTCCAGTGAGCTCATCCAGCATCTTATCAAGCACAGCGACACGAACACCGCCAAACAGCGTCAGCCCGTCACGGGGCCTCGGAAGTACAAACGACGGCGCAAGCTGCAGCCGCATGAGATTGCCCACATGCGGGCCGAGAACAAGGAAGATGAGCTCTTGCAAGAGGCCGAAGAGTATAACAGTGACTTAGACATCTGCGACTTTGATGTGGAGAACGTGGACCAAATCTTCGAAATGGCCGAATCCCCCAAAAAGGAGAAGCGCAAAAAGGGGGCATCCAAGGATCCGCAGGCGGTGGCCAATGGAACAGCCAAGGCTGTCACGGATAAGTCGAAAATGCGGTACGATTCCACCAGCAGTCACTCGGATCGCATGTGGGAGGAGAAGTTCCTGCACGACAACCAGGTGTCGTTGTTTCAAATTGATTCGTTAACGGCTATGAATCAACAGCAATCACCGCTGCCTACCAGCACCGCCAGTTCCTCCAGCGTTCAAAACACGAGACGCAGTTCAAAGCAGTCACAGGCCCAAGGGCAGGCCAAGACGGCGCCACCAGTTGAGGTAAAAGCAAACCCCAGTGCATCATCCTCCTCTACGACAGCGAGCtccagcagccgcagccgaaAGAAGGCGGGAACAAGTAAGGCGGCCAGTAGCAAATCGGCTGCTGCGGGAAGCTCGCGGCCGCGAATGATCCACACCGAGAAGGCCAAGGTTCCGAAGGCTGCAGAAAACTCGGGCACTGCATCCGGATCTACCAAGAAGACGCGTGGCAAGAGTTACATTACCCGGACAGAGACAAGCAATCTGGATCTGCTttccagcagcggcagcggcaagtCGCGATCCACTGCGTCCAACATGGTCGACGACTATGAGATCATATCCCCAGCCACGCATCCACCCAACCAGATCAGCTCCAGTCCCCTGCACATTAAGCAGGAGCAAGAACAGCAGCGCGTTCCGATGATGTACGACGACAATCTGCTCATCGATGCCGCACTGCTCCGTGAAAAGACGTACGAGAGGTTCAACCCCGCAATAGTCAATGATTTGGAGGAGATTCTGCGCTCTCCACTTAAAAGTGAGCACAATTCCCGACTGCGTTTCACCAGCGAGTCATCGACAACGCCGCAGTTTCTGCCCGGGGAGGAGCAGAACCTCATCAAGATCGAGCCGACATCCCCCGATTTACGCGAAATGGTGGAGAGTCAGCAGCGCGTCACGGCTACCACTGGCAACACGCCCTcttcctcgtcgtcgtcggcccGTACCTCGCGTCACCTGCGCCAGATAACTGCCAACAGCCCGCGAGTGGGCAGCAAAcgttccagcagcagcaggccggACTCTGCATCCGGCGCGGCAGCCAAGAAGCCCACCACATCGTCCTCCTCTTCGCCAGTTGCAGCCGGGAGCAAGACCAGAAGCTCCGAACACTCGTACCTCAGCTACGGCGTGGGCGTGGACTCCTACAATGTGAATGTACCTGCCAGCGCCAACACTGCCGATGTGAGCTCTGCTTTCTTTTCCATTTCCGAGGTGGTTTCCGCCGCCGACGCAGCCGATGCTGCAGCCAAGGCAGCCGCAGCCAGCAAATCGGACCGCAAGAAGCGCAGCTTCGAATGCGAGATGTGCTCGGCCATCTTCTACGACCGCGCGCAGCTGCTGGACCAcgtccacatccacatctag
Protein Sequence: MNHQNYGGIQWIQQHPAASDSGVDILVGDGVTPDGYHLVTDEATGEDLDHMAAENLIFMARDGQLSEIIAGGNAVIVTADGHGVTYADSFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMEQDEYTALRPYPCDFCSRRFKKKSSLNTHMLAHQNDRPHLCKLCGSRFSRRAELISHFKAHAEAQDAADAEAAAATSIKFEHRPMDDHYYEHEWPLYQQDQDAEDQQQLVSSSETQLVHQNSYNVAAVTVDAPVPTRGRISRLKPKEEATQYIAISDKTEAPEMQDYMQSEPMQAVVTTSTAIEPPPKADLPQPNYPVLDDSKPFVCQQCGLAFAREKALFSHTKNHRVDSPFECNQCQEMFWDNSSLLEHQKTHQFEESNSEYDPASGDDSVSESEPDQLYGDFYCSECGICFHRQDLLRRHAKCHFQQPDASNFDQKPIVGEVGVTDEVIAGDAENAKDDAAHRCHTCGKCFPNSVALSAHAEIHARFPLFKCVLCGVSFYEEQAIKRHLHSRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGMDVTLGTYHCEVCSEDLSSSSELIQHLIKHSDTNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAENKEDELLQEAEEYNSDLDICDFDVENVDQIFEMAESPKKEKRKKGASKDPQAVANGTAKAVTDKSKMRYDSTSSHSDRMWEEKFLHDNQVSLFQIDSLTAMNQQQSPLPTSTASSSSVQNTRRSSKQSQAQGQAKTAPPVEVKANPSASSSSTTASSSSRSRKKAGTSKAASSKSAAAGSSRPRMIHTEKAKVPKAAENSGTASGSTKKTRGKSYITRTETSNLDLLSSSGSGKSRSTASNMVDDYEIISPATHPPNQISSSPLHIKQEQEQQRVPMMYDDNLLIDAALLREKTYERFNPAIVNDLEEILRSPLKSEHNSRLRFTSESSTTPQFLPGEEQNLIKIEPTSPDLREMVESQQRVTATTGNTPSSSSSSARTSRHLRQITANSPRVGSKRSSSSRPDSASGAAAKKPTTSSSSSPVAAGSKTRSSEHSYLSYGVGVDSYNVNVPASANTADVSSAFFSISEVVSAADAADAAAKAAAASKSDRKKRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480991;
90% Identity: iTF_00601198;
80% Identity: -