Basic Information

Insect: Drosophila percnosoma
Gene Symbol: ush
Assembly: GCA_035043855.1
Location: JAWNMQ010000032.1:1118371-1136598[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.052 3.4 8.3 0.0 1 20 202 221 202 223 0.89

2 9 0.0003 0.02 15.3 0.8 1 23 278 300 278 300 0.98

3 9 0.054 3.5 8.3 1.0 2 21 351 370 351 371 0.92

4 9 0.037 2.4 8.8 3.0 2 21 750 769 749 770 0.93

5 9 0.0097 0.64 10.6 0.0 3 21 820 838 818 839 0.91

6 9 0.02 1.3 9.6 0.0 2 23 909 930 908 930 0.98

7 9 0.0041 0.27 11.8 1.3 1 23 936 958 936 958 0.99

8 9 0.0013 0.086 13.3 1.8 1 23 1024 1047 1024 1047 0.96

9 9 0.33 21 5.8 0.7 2 20 1156 1174 1155 1176 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.052	3.4	8.3	0.0	1	20	202	221	202	223	0.89
2	9	0.0003	0.02	15.3	0.8	1	23	278	300	278	300	0.98
3	9	0.054	3.5	8.3	1.0	2	21	351	370	351	371	0.92
4	9	0.037	2.4	8.8	3.0	2	21	750	769	749	770	0.93
5	9	0.0097	0.64	10.6	0.0	3	21	820	838	818	839	0.91
6	9	0.02	1.3	9.6	0.0	2	23	909	930	908	930	0.98
7	9	0.0041	0.27	11.8	1.3	1	23	936	958	936	958	0.99
8	9	0.0013	0.086	13.3	1.8	1	23	1024	1047	1024	1047	0.96
9	9	0.33	21	5.8	0.7	2	20	1156	1174	1155	1176	0.91

Sequence Information

Coding Sequence: ATGATCAGCAgtcaaacaacagcagcaacaataaaagGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGAATTGGCCGCACACGAGCTGAGCGaggagaagcaacagcaacaccagcagcaccaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCCTGCAACCCGTCGAGACTGACATGGACCAGGAACTGGAGGAGGCACAAGCGGCAGCCCAGGATTCCAGCGAACAGAAGTTGGAAGATAATCCGACAATGACAACGCCGCCGCGTAGCCCAACGCCCGAACTGGTGCCTAAGCTGGAGCGAGCTGATACGCCGCCCTCAGTTCCGGTCACGCCCAGTCCACCACCGCGTACGCCCACACCGCCGCCAATTGTGCTGCCCAAGCTGCGACTCAATGCGTTGCTTGCCTCCGATCCGGCATTGAAGCCCGATGCCAAGGAGCTCAATATGCACGAGTCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAACCGAGTCTGCAGCCGGATGTGGAGCCGCTGTTGAAACCGGCGCGATTTATGTGCCTGCCCTGCAGCATCGCTTTCAGTTCACCCTCAACACTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGCAACAAGGACGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCcaatgccaacagcagctccaGCGGCTCAAGTGCCACCGGCTCCGAGCCACCCAACAAGGTGTCCCGCATTGGCAAACAGTATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGACACATGCGCATGCATCAAACATCCCCAGCGGCACCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAATGGTGTTGTTGCCgcggctgctgccgccgccgctgcggcagctgccgctgctgctggtgcgcaGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGCGACGGACAACTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGAAGTGGAGTtggtggagctggagctggtggtggaggtggagctgtatcagttgctgctgttgctgccggcaAGCACAGCCCACAGACGCGCAATAAGACGCCAACGCCAGCaatggttgctgctgccgccgccgcggctgcggctgctgctgcctcgctGCAGGTGGCACCACCGCAACCCTTCCTAGCGCTGCCCACCAATCCAATTATCATAGTGCCCTGCTCGCTAATACGTGCAGCCAGCTTGATACCGGGACCACTCACCACCTCAACGTCGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACAGCTCTAAACATAAATACGCTAGGCGGCAGTGCCACGCCTACGCCTATGCCTAGCAGCAATCAGATACCGATTCCCGCTTTAGAGCCAGATCGTCCAACCCCGGTGAGCATTTCAAGCAACCTGGAAACTGAACCCAAGAAAAGTCCACCAGAACCGAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACACCCCTGGATTTGTCGCTGAGGCGCTCGCCAATCTCTGCGCTATTGCAGCGCCAGCGTATCGCGCGCTCGGCCGCTGCGCTGCTGGACGCCGAGGATGCTGCAGGCAAGGATTCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCACCCAAACGACGTGCTTTAAGTCCACGCAGCTCGGGAGCTGGGAGCGCTTCGTCGATGTCACCGCCAGCCCATCACATACTGGATAATTTGCCGCCATTGCGCTCCATGCTGCCCTCCGACTTTAATCTCTCCGAATCGCTGCTGGCCAAAACAAATCCAGAGCTGGCCCTCAAactggcggcggcagcagcggctgctgtggCAGGCAGTGGCTCGGCGGAGCTGGCTAAACTAGGATTTCCAGGAGGCGGTGCAGCAACCAGCAGTGGTGCTACTGCACCATCCTCTGCACAGAATGCACCGCAGATCTATGTGAAGCAGGGCGTCTCCAAGTGTAAGGACTGCAATATTGTATTCTGCAAATATGAGAATTATTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAGACGGGCCTGGATGGAGAAGCCTCCAAGAGCGCTGTAACGCCCCCCAGTGGACTATCGTCAGTTGGCGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCCGCCTGTGGCATTAAGTACACCTCGCTGGATAATTTGCGTGCGCATCAGAATTACTACTGTCTGAAAGGAggcgctgcggctgctgccacGCCAGCTgaggcagcaccagcaccacaacTGCCACTCGCGCATCCCAAGGAGAAGTGCCCGAAATGCAAGACTCATCATGAGCACGGACAGAATTGtccaccacctccaccaccgGCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTACCACGTCGAATAGTGTCAATAAGTGCCCCGTTTGTGGCGTAATTAGTCCCACAGCTGCCCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATCCGCACACATTTCGATAAGAAGACCAGCGATGTGAATGAGGAGCACTACATGACATGCATCTTTGAGGAAGAtgctgcagcagtggcagcttcagttgctgctccAACTCAATCCTTGAATCTAGATCTGCCCGCtgtggcagcggcggcggcggcagcagcagcagcagctcaagagCAACTGGAACAGCATCCAGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTATAAGGGCAATGTGctgCGTCACATGAAATTACTGCATCCACATGTGGCCATTAGTTCGCCCTCCATTTCACCCGAGTCGCGCGAACACGAAGCCAATCCTCATGTCCTACCCGAAATATCGCTGGTTAATGGGGAACGGGAGGCAGCATCTATGCCCATCTTCCACATTAAAACGGAGGCATTGGAGGCACCGGTAGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTGGCCCACTTACCCACATTAAAGCAGAGCCCATGGAACTTGGTGTAGATGTATCAGTACCGTCTCTACCCCCGCCGATGGCCAACTCGCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTAAAAACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCACTCCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGCGGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagaAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MISSQTTAATIKGDCSDTTEEMTVDSRDSKELAAHELSEEKQQQHQQHQQQQQQLEDQAEDEQLEQQSNNSSLQPVETDMDQELEEAQAAAQDSSEQKLEDNPTMTTPPRSPTPELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNMHESRLLGPPPKPEQQPSLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSSATGSEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAAAAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGITGSGVGGAGAGGGGGAVSVAAVAAGKHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPMPSSNQIPIPALEPDRPTPVSISSNLETEPKKSPPEPKRKETSGIRETTPLDLSLRRSPISALLQRQRIARSAAALLDAEDAAGKDSHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHILDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFPGGGAATSSGATAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQETGLDGEASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSTTSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAASVAAPTQSLNLDLPAVAAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHVLPEISLVNGEREAASMPIFHIKTEALEAPVATLSLVHENNNSPIGPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPLRPEANDSPSPTVGGGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -