Basic Information

Insect: Drosophila percnosoma
Gene Symbol: RREB1
Assembly: GCA_035043855.1
Location: JAWNMQ010000261.1:144912-151628[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.037 2.4 8.8 0.8 1 21 237 257 237 259 0.93

2 13 0.00035 0.023 15.2 0.2 1 23 269 291 269 291 0.98

3 13 0.00026 0.017 15.6 7.2 1 23 297 319 297 319 0.98

4 13 0.91 59 4.4 1.5 2 20 551 569 551 571 0.93

5 13 0.017 1.1 9.8 0.2 1 23 715 737 715 737 0.97

6 13 1.3e-05 0.00083 19.7 0.7 1 23 747 769 747 769 0.99

7 13 0.00086 0.056 13.9 2.0 1 23 775 798 775 798 0.97

8 13 0.0031 0.2 12.2 2.0 1 23 1063 1086 1063 1086 0.95

9 13 8.9e-05 0.0058 17.0 0.3 2 23 1470 1491 1469 1491 0.97

10 13 0.15 9.8 6.9 6.3 1 23 1497 1520 1497 1520 0.97

11 13 9.7 6.3e+02 1.2 3.4 1 23 1640 1663 1640 1663 0.78

12 13 0.0087 0.57 10.7 0.5 3 23 1722 1742 1720 1742 0.96

13 13 0.0014 0.09 13.3 4.8 1 23 1748 1770 1748 1770 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.037	2.4	8.8	0.8	1	21	237	257	237	259	0.93
2	13	0.00035	0.023	15.2	0.2	1	23	269	291	269	291	0.98
3	13	0.00026	0.017	15.6	7.2	1	23	297	319	297	319	0.98
4	13	0.91	59	4.4	1.5	2	20	551	569	551	571	0.93
5	13	0.017	1.1	9.8	0.2	1	23	715	737	715	737	0.97
6	13	1.3e-05	0.00083	19.7	0.7	1	23	747	769	747	769	0.99
7	13	0.00086	0.056	13.9	2.0	1	23	775	798	775	798	0.97
8	13	0.0031	0.2	12.2	2.0	1	23	1063	1086	1063	1086	0.95
9	13	8.9e-05	0.0058	17.0	0.3	2	23	1470	1491	1469	1491	0.97
10	13	0.15	9.8	6.9	6.3	1	23	1497	1520	1497	1520	0.97
11	13	9.7	6.3e+02	1.2	3.4	1	23	1640	1663	1640	1663	0.78
12	13	0.0087	0.57	10.7	0.5	3	23	1722	1742	1720	1742	0.96
13	13	0.0014	0.09	13.3	4.8	1	23	1748	1770	1748	1770	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagtagcagcagcagcaacacaagaGGATGCTCGGGATTTGGGATTAACGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAaaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAgccacaccagcagcagcaacagttgccgctcTCCGAtgaggagcaacagcagcaacagcagcagcagctgttggatTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGcagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAATCGCAGTagcgccagcagcaatgcCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGTGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCCTCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGgcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCAGGCGGAGCAGGCGCAACTGGCTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCTAGTGAACTAAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataataacaacaacaacaacaataataataataataataataatgaggaTGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCGCAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGACGTGGACAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGCTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAAAGCGAactggaggagcagcagcagcagcacgaggAGGATCACGAAAAACAGCACAAGCAGGAGGAACAGGAGCACACCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAACAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGTTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCACAGGATGCTTTCACTAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTACGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGACATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCCTCGTCACAGCTAAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTaaaagtaacagcaacagcagcagcaacggtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacagcagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCacgccgccgccaccagcaacggcagcagcagcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaACAGCAGGAACAATTGCTGCAATGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGTGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCTTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcaactgccgcAGCAATGAGTAATCTcacccagcagcaacagttgcagcagcaacagttgcagcattcacattcacatcaCGTCCATGCCCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcagcagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAGaggacgatgaggatgaggaggaggatcAGGAATTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACGTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgacgatgatgatgatgttgatgatgatgctgcagcagcagcaacagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCACCCGCATTCTCAAGCGGAGTCCCTGAGCGGCAATAAGCCGGCGGCGCctacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGTCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAAGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgggaacgggagcgggaacaacaacatttgatCCAACAGTATCGCCAACAAatggccgctgctgcagcggctgctgttgccgttgccgctgTCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAActgcagcatcaacagcaacagttgccaatGGCTGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAGTATCCCGACTATAGCAACCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGTATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGCTGCCCTGCTCCCCACCTTCAACGCCAACGCCcactaataacaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQPQQQQSHTAAATAVAAAATQEDARDLGLTETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQLPLSDEEQQQQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVIVAAAAQSLSQQQQQRRQRSMRQALAARACSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNNNNEDELELEDEQLVLSNKQRRRKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEKQHKQEEQEHTEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAAAAADKSMPTNPAAAAGATAGTIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAATAAAMSNLTQQQQLQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQQQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEDQEFDVDEDEQEDEEMDVDDEHQQQPHEEDDDDDDDDVDDDAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKHPHSQAESLSGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -