Dpen005601.1
Basic Information
- Insect
- Drosophila peninsularis
- Gene Symbol
- -
- Assembly
- GCA_035047485.1
- Location
- JAWNPN010000035.1:6388540-6389152[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 3.4e-23 3.3e-20 72.0 16.8 1 70 88 158 88 158 0.96
Sequence Information
- Coding Sequence
- ATGGATCAGAAGCGCGCCATGCTCTATCCCCAAGTGGATTTCAACACGCCCAGCGCTCCGCTGCCAACGCCAACGGCCGAGTTGACGGTGCCAACGCTGGAGGCGCCGCCGTCATACGATGTGGCAATTGCAGCACAAACTCCAATTGTGATCGCACAGCCACAACCACAGCCAAcaccaccacaacaacagcaacaaccacagcagcagccagaacaGTTAGAGCCCACATTAGTCCAAACAGCAGCCACAAATTTGGGTCCGAATCCCTGCCGTGTGCTGTGTCCCGCTTGTGGCGCACAGAAGACCACACGCATGACGCACACAGCCAACGCAAGGACTCACCTGGCCGCAGCCCTCATCTGCCTAGTGGGCTGGTGTGTCTGTGCGTGCTTTGTGCCCTATTGCATGAATAGCTGCCGCACAGGTAACCACTATTGCCGCAAGTGCAACACCTTTCTAGGTGTCTACAATCCGCAGGGCGTCAAATGA
- Protein Sequence
- MDQKRAMLYPQVDFNTPSAPLPTPTAELTVPTLEAPPSYDVAIAAQTPIVIAQPQPQPTPPQQQQQPQQQPEQLEPTLVQTAATNLGPNPCRVLCPACGAQKTTRMTHTANARTHLAAALICLVGWCVCACFVPYCMNSCRTGNHYCRKCNTFLGVYNPQGVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00520300;
- 90% Identity
- iTF_00568643; iTF_00587076; iTF_00551976; iTF_00599978; iTF_00559888; iTF_00544890; iTF_00547036; iTF_00513131; iTF_00532780; iTF_00494060; iTF_00473454; iTF_00479848; iTF_00549936; iTF_00540764; iTF_00545646; iTF_00516664; iTF_00572987; iTF_00477020; iTF_00510207;
- 80% Identity
- -