Basic Information

Insect: Drosophila pegasa
Gene Symbol: ken1
Assembly: GCA_035046225.1
Location: JAWNOD010000322.1:1114256-1116613[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.021 1.3 9.5 7.0 3 23 246 266 244 266 0.96

2 12 0.00022 0.014 15.7 0.9 1 23 272 297 272 297 0.94

3 12 0.0053 0.33 11.4 0.4 2 23 305 329 304 329 0.93

4 12 0.00059 0.036 14.4 5.1 1 23 339 361 339 361 0.97

5 12 0.00021 0.013 15.8 1.9 2 23 369 390 368 390 0.96

6 12 0.0073 0.45 11.0 0.5 1 23 396 418 396 418 0.97

7 12 0.02 1.2 9.6 2.6 1 23 424 447 424 447 0.97

8 12 0.0016 0.097 13.1 1.9 1 23 453 475 453 475 0.97

9 12 0.0044 0.27 11.6 0.6 2 23 482 503 481 503 0.97

10 12 0.00019 0.011 16.0 0.8 1 23 592 615 592 615 0.95

11 12 0.096 5.9 7.4 1.3 1 21 621 640 621 643 0.75

12 12 6.3e-05 0.0039 17.4 2.2 1 23 649 672 649 672 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.021	1.3	9.5	7.0	3	23	246	266	244	266	0.96
2	12	0.00022	0.014	15.7	0.9	1	23	272	297	272	297	0.94
3	12	0.0053	0.33	11.4	0.4	2	23	305	329	304	329	0.93
4	12	0.00059	0.036	14.4	5.1	1	23	339	361	339	361	0.97
5	12	0.00021	0.013	15.8	1.9	2	23	369	390	368	390	0.96
6	12	0.0073	0.45	11.0	0.5	1	23	396	418	396	418	0.97
7	12	0.02	1.2	9.6	2.6	1	23	424	447	424	447	0.97
8	12	0.0016	0.097	13.1	1.9	1	23	453	475	453	475	0.97
9	12	0.0044	0.27	11.6	0.6	2	23	482	503	481	503	0.97
10	12	0.00019	0.011	16.0	0.8	1	23	592	615	592	615	0.95
11	12	0.096	5.9	7.4	1.3	1	21	621	640	621	643	0.75
12	12	6.3e-05	0.0039	17.4	2.2	1	23	649	672	649	672	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACACTCGATATGTCGCATTTGCTTGAATCATTTGCGAAACGAACCGGCCTACGACCTGTTTCTTGTCCCTGGTCTGGCCAAGAAACTCTGTGTGTGCACTTCACTCTCAGTGGAGCAGCACGACGGCTTCCCGAAGAACCTTTGCTCCACCTGCCATACCCGGCTCAATGACTTGCACGGATTCCAGAAGCAATGCGTGGACTCCGTGCAAAAGTTTCAGGAAATGGTCGCGAGTAATTACTTCGTTCCTGTCGTGGGCGATGTGGACAAGGTTGATGTGATGCACGATGCAGCGGCTGATGGGGACATGGAGGAGGATCGCTTAAACTTCGATCCGCTCCTAAATACTAAGATAGAGATAGTGGAGACTGAAGATGTTTTTAAAATGCTAGACGATGTGGACAGAGAAGTCGAGGAGGTTGAGAAGGAGCTCTCGAGTGGGAACGAGAGCGACAACGATGACGATCCAGAATTCGAAGTAAACAGCAGCAATTCTGAAGATGCTGTGCCCCTGTCCCGCTTGCGAAGTGTGACTAGAGCATCGAAAGCAAAAGCCAAGAGCAAACCTGTAGTAGATGACGATGATTCTTCGAGCTTCGAGTGGAACACTAACAATGATGGGGGCAAGGAAAAGcctaaaacaaaagcgaaagtgAAACGTAAACGCATGACGAGGAGCGAGGCATCACTGGATACCGATCAAATAGATTGTCAcatttgccataaaaaattCAAGAGTACCAATCTGTATGATGAGCACATGAAGCATCATAATGATCTCTTGCCCTTCCAATGCACTGTGGAGACCTGCAAGAAGGGCTTCACCACGTCTGGCGGTCTACGCCTGCACATGGACCACGCTCATTCGGAACTCTCAGAGGTCCACGCCTGTTCTTTTGAGGGATGTGGCATGACATTTCCTCGGCCTGTTCTCCTAACATTCCATATGAAGAAGGTGCACAAAGTAGTCACGTCTCGGGCCAAGGATCATCCTTGTACGGAATGTGATAAGGTATTCCGTTGTTCGACGGCCCTGAAGAAGCATATGTACAAACACACCGGAGAGGAGAAGCCGATTTCCTGCAATATCTGCAACAAACGTTTCCACATCAACAGCGAACTCAAGGATCACCTCTTGCGCCATGCCGGAGTGAAGAATCATGTGTGTCCCTACTGTGGCGTGGGTAAGACAACTCGTCAGGAGTGGAACAAGCACATATTGACGCACACCAAGGAGAAGCAGTTCCAGTGCCGCCAGTGTGATCACTCCTCCCACAACAAACAAGCTCTGGCCAATCACGTCAAAGTGGTTCATCTGAAGATTAAGAACTATGCGTGTCAGTACTGCGGCAAGACTTTTGGCAAGTCGTATGCCTGCAAAATCCACGAGAGAATCCACACTGGGGAAAACTGTTCGCAGTGTAAAATATGTGGTAAAGTCTTGCTGTTCGAGAGGAGCTTGACCAAACATCTGAAGATTCATGAGAAGCGAGATCTACGGGCATCAGCGACCAGTGCGACGCCACAGGCAGTTGACGAAGCGCAGAACAACCAGAATCTGAGTCGAGATGCGAGTGACCCGATGGAGATGAAGCCCATTCCAGCAGAGCAAGCCAAGCCGAGAAATTCAAATAGGCTAGAGCGCGTAGATATATCCCAGTTGGCAGGCACCTCCGTCAATCCCATTCCAACAGTCTCTGTGGCATCCTGGGCACCACAGGTGAACTTCACTAAGAAGGAGGGTCAGCACATTTGTCCgggatgtgggcgtggcttcaACCACATAGGTAATATGAAACTTCACTACAAGATAATTCATGAGAAGGTGAAGGATTTCGCCTGTCGCTTCTGTCCCAAACGATTCTCAAAGGCCCAAATCTTGCGGCATCACGAATGGATTCATACGGGTGAAAAGCCGTATGAGTGCAAGATATGCGGCAAGCACTTCCGCCAGGAGCAAGTGATGAAGACGCATGTCAGAAAAGTACACGAGAATCCGGCGAAGCCACGCCGAGAACCAAAGCCCCAAAAAGCTGCAACAGAGAAGAGATCGAAGATGAACCTCAACACAAAGCCACCTAAGATCCTTGACGAGTACCAAGATCCTGCTGCAGAGCGTGCTGCAGCAACCGCTGCGCTGCTCGCTCAACAAATAGAGGAGAGCCAGGCGAAGCGCAAGGCCGAGGAGGAGATTCGGAAGATCCAAGAAGCCGCCTGTGAACAGCTTCAGATGCTGCAGAAGGAGCAGCTCATTGACAAGCTGCCCAGTGATAGCTTTCAAGTGAAAAAGCCCGAAACAGGCATCAGTGTGGATGACCTTAAACAGGATTAG
Protein Sequence: MNEGSEYSIHSICRICLNHLRNEPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCSTCHTRLNDLHGFQKQCVDSVQKFQEMVASNYFVPVVGDVDKVDVMHDAAADGDMEEDRLNFDPLLNTKIEIVETEDVFKMLDDVDREVEEVEKELSSGNESDNDDDPEFEVNSSNSEDAVPLSRLRSVTRASKAKAKSKPVVDDDDSSSFEWNTNNDGGKEKPKTKAKVKRKRMTRSEASLDTDQIDCHICHKKFKSTNLYDEHMKHHNDLLPFQCTVETCKKGFTTSGGLRLHMDHAHSELSEVHACSFEGCGMTFPRPVLLTFHMKKVHKVVTSRAKDHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHSSHNKQALANHVKVVHLKIKNYACQYCGKTFGKSYACKIHERIHTGENCSQCKICGKVLLFERSLTKHLKIHEKRDLRASATSATPQAVDEAQNNQNLSRDASDPMEMKPIPAEQAKPRNSNRLERVDISQLAGTSVNPIPTVSVASWAPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPYECKICGKHFRQEQVMKTHVRKVHENPAKPRREPKPQKAATEKRSKMNLNTKPPKILDEYQDPAAERAAATAALLAQQIEESQAKRKAEEEIRKIQEAACEQLQMLQKEQLIDKLPSDSFQVKKPETGISVDDLKQD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532579;
90% Identity: iTF_00502729;
80% Identity: -