Dpeg003886.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pegasa
Gene Symbol
hang
Assembly
GCA_035046225.1
Location
JAWNOD010000085.1:204593-217836[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.37 23 5.6 1.0 3 23 487 508 486 508 0.93
2 18 1.1 65 4.2 3.2 3 22 615 634 613 634 0.89
3 18 0.00079 0.049 14.0 3.3 1 22 728 749 728 751 0.90
4 18 0.4 25 5.5 0.1 3 21 764 782 763 783 0.94
5 18 0.00091 0.056 13.8 0.2 2 23 917 939 916 939 0.95
6 18 0.0026 0.16 12.3 0.1 1 23 947 970 947 970 0.96
7 18 0.0002 0.012 15.9 0.2 2 23 1056 1077 1055 1077 0.97
8 18 0.00038 0.023 15.0 2.9 2 23 1143 1165 1142 1165 0.97
9 18 0.03 1.8 9.0 0.2 2 23 1174 1196 1173 1196 0.95
10 18 0.0016 0.097 13.0 0.1 1 23 1209 1232 1209 1232 0.97
11 18 0.00016 0.01 16.1 1.1 1 23 1274 1296 1274 1296 0.99
12 18 0.0026 0.16 12.4 0.9 1 23 1304 1327 1304 1327 0.96
13 18 0.089 5.5 7.5 0.4 2 19 1335 1352 1335 1353 0.94
14 18 3.5e-05 0.0021 18.3 0.4 3 23 1463 1483 1462 1483 0.98
15 18 0.0066 0.41 11.1 0.1 1 23 1518 1540 1518 1540 0.97
16 18 0.00078 0.048 14.0 0.6 2 23 1629 1651 1628 1651 0.93
17 18 0.0084 0.52 10.8 0.3 3 23 1707 1727 1707 1727 0.98
18 18 5e-05 0.0031 17.8 2.3 1 23 2208 2230 2208 2230 0.99

Sequence Information

Coding Sequence
ATGGTTGCCCGCCGCTGCGACGATGACTCTCTGGACTGCGCCCCCGGCAACGACATCATCATCTACGTCGGCGTCGTCAAcacgttgctgctgcgtgtgcTGCTTGGTGCTTGGTGCTGGCACTGGatcaCATCATTGGATCGTCTGTCGCTGCACATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGGCCAAGCAGCGCCAGTGGCTGGAAAGCGATAAGAACAAGCAGCAGACGCTATTGGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATtgaacagcatcagcagcagcacgagtcGAATATTGATTCGGCAACGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATTCCTTCGTTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCcaagcaacagctacaacagctacagcagcagcagcaacaacaacatcaacagcagcagcagcatgcagCAAGAGCATCGAgcgcggcgacggcggcggcggaatCCCAGCAAACGCTTCAGACCCTTTTATTGCAGGTGCcctccgcagcagcagctttggcAACGTCGTCCacccatcagcagcagcagcagcaacagcaacagcgcaaatatcaacagcagcagcagcagcgtgtcAAGCAGCAGCACTACCACCAGCAACATCTACAAAgtcagcagcatcatcagcatcagcgcTTGAGCCGCATTCGTCAGCcgagacggcagcagcaggcgaccaTGTCCGCCCAGCGTCTGGTCAAATTCAAGccgaaattgttgttgccactggATATAGcggtgccgccgctgccacccTTGCTGCCGACGCCGTCGCAGCAGGCCGACAcggttgctgctggtgctaaGTTggcgccgttgccgttgccgctgccgctgccacttgATTTTAGCCAGAGTCAGCATCCGAATCCGACTCCGAGTCAGCCGAAGCATGGCAGcgtgttgccgctgccgttgccattgccagtgccgccgtcgacgccgctgttgccgccgctgccagctgcaacaGTGACCAGCAACGCCGCTGCATCtagcgctgcctctgcctctgcatCTGCCTCTGGCTCTGCATCTGCCGCAGGTGGAGCCGCAGTCACGACTCCTCTGCTCATGCCGCCGCTGCCCGCCGTGCCGATCAAGGACGAGCCCATCGACGACACGGACGATGACTTTCAAATGAAGAGCATAGACGAGTCCGACGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACGCGACGCAACACGGCGTGACGGCGGTTGCGGCGGCAGCCTCGCTGCCCGCCAGCGCGGTTGCCAACGTGGCCGCCGCTGGCGACTCGAAGGTGGCCAGCTGTCGGGCCTGCAGCTTGCAGTTCTCGACGCGCGCGAACGCCCGACGCCACGAGCGCAATCTGCACCCGAATCTGTTTCAATTGTCGACAGACTCGCCGAACAATACGCCGATCACGAAGCCAACGCCGGCACTGGCCGCCGCACTGGAGATTCAACGGGCCGCCGCGGCGGCCGCAGCCACAGCGGAAGCGACCAAAGCCGCCGCCGGCGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAATACGTTCATCAAGTGCGAGAATGGCGGCTTCGACTACGACAATCCGGAGCAgtaccagcagctgctcacgCGCGACAAGGTGGAGTTCATCCAGGAGAACAACGAGTTTCTGGAGCAATACCAGACGATgacctgccgctgctgcaacaaATACTTCAACACCTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTatccgctgctgccgcgcaaCCTCTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTCTTCATATCGCATCTGAAGAAGCGCAACTGCATCAACTTGTATCGCGTGCTCAATGCGTTGCGCCTGAAGCTGCCGAACTTCTCGCACGCCAACGCCTCCGGCGTGGCTATCTCGTCCGATCTGAGCCTTGGCCAGGCGGCTGGTGGGGCGCATGACACCTCAGCGGAGCGGCCGGAGAAGCTGCGTGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTCTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGAACCTGTGCAGCTTCTGTGGACTGGACTTTGCTGATCCCGTCGACCGACGGCGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGCGACGCCAAGCTGGAGACGCATCAGCGCTTCCTCGACCACGTCTACCAGGATCACTTGGGCGGCGTGAGCAGTGACAACGCCTCGACGGCCAACAGCGGCCTGGACCACTCGCCGGGCAAGCGCAGCCTGCTGGGCGCCCTGGGTATCGGCGCAAGTCAGTCCTCCAACGATGAGTCGCGCGGCAgcacgcacaacaacaacaatgccgtCGAATCGCCCTTCACCTCAACGCCGAAACCGGCTGAGATGGGGGGCGGCCtagcatctgctgctgcggcggcagctgccggcggcggtggcggcggctccACGTCGGGCAGTCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCCATCTGCGGCCAGCagtacaacaactacaacaacgtGCTCCGCCACATGGAGTCGAAGCATCCCAACAAGCTGCCCGAGACGTACAAGTGCGTGCGCTGCGGCCTGGGCTATCCGCGCATCTCCTACCTGCGCGAGCACATGATCAATGTGCACGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATTGTGAATGCGGATGCGGTCAAGCTGGCGGACGGCAGCACGCCGAACGTCTACACCGGACGCTACGACTATGTGATGAAGGATTTGATGTCTATAACAAATGGTGGGACACTcgatgatgaggatgaggaaGGCGGAAGCGTTGCCAAAAAAATGCGGCTCgatgacagcagcaacaacagcagcatcaacatgAGCCTGGCCAATCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTgttcagcaacaacatcggCCTGTCGAACCACATGCGCTCGCATTACACCGCctcgacgacggcgacgaatGCGGCGCTGGCGGCTGCCAATCGCATGACACCCAAATCTCTGACAATTACTGCAACGCCGCCCTTGGAGACGACCTTGCCACCGGCGATGGTGCATCAGACGCCGCAGGAGCAGGCCGTCTTCCGGCGCAGCTTGGACCAGGCGGCCGATCGTCGCTTTCGCCGCATGCGCTGTCGCATCTGCCAGCGGCGCTTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTGACCGACCACCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCCGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCACCTGTTCAAGGTGCACGGGCGGGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGACATCTGCTCGATTGTGTACAGctccgagctggagctgcagcagcacaagcgcaGCGTGCACAAGTCCCAGCTGGGCGCCAACGATGCCTCGAAGTCGTCAACCAAATCGTCTACCGCTACCTCAGCCTCGGCTGACCTGGCCGACGCATCCGGCACGGCTGCGGCCGTCCTGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGACTATTCGTGCAAGGATTGCGGCAATGTCTACAGCGGGCGCAAGAGCCTCTGGgTGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCGGCCGAGTGCACGCTCTGCCGCAAGATGTTCTTCGACCGGCAGATGCTGGAGAATCACACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAGgatccgcagcagcaacaccagcaacaacaacaacaacagcagcagcagcaacagcagctgcagcagcagcaacagcaacaacaacaacgcaccATATTCAAGCATAAGACgggcgacgatgacgacgaggaggatgaTGACCAGCTAATGATGCTGGAGGATGGGCTCcttggcagcgacagcaacggcGCCAATGTGATCCAAGCGGCGGCCGCAAGCGCCGGCAATCCAAATACGCTAAATGCGAGCACACTGAAGATACGCATACCGGAGGTGGCGTGCACCATTTGTGGGGCGCGCTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAGCAGGACCTGTATGTGGACAATCCGCTGGCGGCCATGTTCGACGATGGCCCCGCCGATGCGGGCCAGTTTCAGGTGGAGCGCCAGAACGAGAACGGGGAGTATGCGTGCGACTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTGCGCGAACTGCATGCAGTGGGCCTGATgcccaaccagcagcagcaccagaagcaactgctgcaacagcagcagcagcagcaacagcaacagtcgcagcgGAACAACACGTCGAGCAGCTCGAGCAAGTCGATGAAGCGAAAGCGTGAGCTGAAATGCGAATATTGCGCCTCCACCTtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCGGAGCCGCCCGTCATCCAGGTGGACGAGCCGCTGACGTGTCGCCGCTGCGGCGACATACGCTTCGATAGCAAAGAGCTGTGGATCGAGCACAAGCTGGCGGACGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAGTGGGGCTGTGACCTGTGCGGCGAGTACCTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCACCTCAAGGAGGACGTGATAGTGCCGGTGCCAACGGCGGCGAATGCCGCCAAAGCAACGCCGCCCGCCAACACCGTGCAGTCCAACAAGaatgcggcggcagcaaaggcagcagccggaataacaacagcaacgacagcgacaacaacagcggcagtgacagcaacagcaggcgcCAAGGCGGCGGCGACACCAGCTGGCAGAATCAAGAGCAAGCCACTGGAGGAGCTGACCATGAAGGTGGCTACAAAGCAGCAGTCGTCGAACGATGACaacgatgaggaggaggaggacagTGATATGgatggcgatgatgatgatgatgatagcgACAGTGGCGATGGGGAGAGCATAAGTGATGACGAGgaggacgatgacgatgacgacgacgaggagggcGACGTCGATGACGATGAGGATGAAGACGACGAAGACGTGCAACAAATgctgcagcaaaagcaacaacaacaacaacagcagcagcagcagcagtccctcaacagcaacagcgtcGTTGCacacgacgatgacgacgatctCATTGAGGAAGTCATCGAGGAAGACGGCATTGTCGAGGAATTGGACGACGATGAGGACGACGACGGGGACGATGAGGGCGACGACGATGGCAACACAACCGAtgagcaccaacagcagcggcgccgccagcaacagcagcagcagcagctggcagcaaatgctaagcagcagcagccacgtcGCCTCAACTTTGACTACTCCCGCTCGGACGGCGCCAAGCTGAACGGCACCGGCAAGCAGACGACGGCCAAGTCAAAGGGCGGGCAGTCCGCGGTGCTGGTCATGCATAGCTCcgaggaggacgaggatgaggagggtgtgcgtgtgcctgtgCGTGTTGGTCGTGTCAATCACATGGATGAGGAGGACGATGACGAGGGCGTGGGTGAAGCGATGACCATTGATGATATTATTGAGGAAGATGATGGggaggacgacgaggacgatgTGGTCGGTGTCGACGGTGGTGTTGTtgaggatgatgatgacgacgacgatgatgatgatgttgaggAAGATATggatgaggatgatgatgaggaggacgacgacgaggacgacgatgacgccgacgacgacgacgtcgacgtcaatATGCGCAACCGCAATCGTCGTCGCGACGGCGCTGTCTTGGTCAGCGGCGGCATCAGCAttgccgacgacgacgacgacgatgatgatgatgaggatgatgatgatgatggtggtgaTGATGGTGGTGATGTTGGTGGTGCAGGTGGTGGAGGCGGTGGTGTTGCCGGTGCTGATGTGGATGGTGATGCTACATCATCATCCGAGAGCGagtcgacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAGTCAGCGGCACatggcgctgccgctgaccAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCAACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGcgggtggcggcggcggcggcagcagcagcagcagcagcggcaggagaGTCGGTGccagcgccggcagcagcagcaccagcagcagcagcagcagcggcggcggcggcaccagcagcagcagcagcaccaggaacaacaacaacaacaataataataacaacaacaacaacaacagcaaaagtaaAACCAAAAAGTCCGGCTTGGAtggcagtgctgctgctgcggcagcaacagcaacagcaacaacaacagcgacaacaagagccacgacaacagcaacagttgccgctgaAGCCACAGCAAGCAGCTTGAACTGA
Protein Sequence
MVARRCDDDSLDCAPGNDIIIYVGVVNTLLLRVLLGAWCWHWITSLDRLSLHICHACISYLNSWQSFKNRCLSSQAKQRQWLESDKNKQQTLLGYLDLNKTENGSSIEQHQQQHESNIDSATIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQLQQQQQQQHQQQQQHAARASSAATAAAESQQTLQTLLLQVPSAAAALATSSTHQQQQQQQQQRKYQQQQQQRVKQQHYHQQHLQSQQHHQHQRLSRIRQPRRQQQATMSAQRLVKFKPKLLLPLDIAVPPLPPLLPTPSQQADTVAAGAKLAPLPLPLPLPLDFSQSQHPNPTPSQPKHGSVLPLPLPLPVPPSTPLLPPLPAATVTSNAAASSAASASASASGSASAAGGAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKSIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYATQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKLPNFSHANASGVAISSDLSLGQAAGGAHDTSAERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSNLCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGLDHSPGKRSLLGALGIGASQSSNDESRGSTHNNNNAVESPFTSTPKPAEMGGGLASAAAAAAAGGGGGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEDEEGGSVAKKMRLDDSSNNSSINMSLANQQKECLICNAVFSNNIGLSNHMRSHYTASTTATNAALAAANRMTPKSLTITATPPLETTLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKSQLGANDASKSSTKSSTATSASADLADASGTAAAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDPQQQHQQQQQQQQQQQQQLQQQQQQQQQRTIFKHKTGDDDDEEDDDQLMMLEDGLLGSDSNGANVIQAAAASAGNPNTLNASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLLQQQQQQQQQQSQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIQVDEPLTCRRCGDIRFDSKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVPTAANAAKATPPANTVQSNKNAAAAKAAAGITTATTATTTAAVTATAGAKAAATPAGRIKSKPLEELTMKVATKQQSSNDDNDEEEEDSDMDGDDDDDDSDSGDGESISDDEEDDDDDDDEEGDVDDDEDEDDEDVQQMLQQKQQQQQQQQQQQSLNSNSVVAHDDDDDLIEEVIEEDGIVEELDDDEDDDGDDEGDDDGNTTDEHQQQRRRQQQQQQQLAANAKQQQPRRLNFDYSRSDGAKLNGTGKQTTAKSKGGQSAVLVMHSSEEDEDEEGVRVPVRVGRVNHMDEEDDDEGVGEAMTIDDIIEEDDGEDDEDDVVGVDGGVVEDDDDDDDDDDVEEDMDEDDDEEDDDEDDDDADDDDVDVNMRNRNRRRDGAVLVSGGISIADDDDDDDDDEDDDDDGGDDGGDVGGAGGGGGGVAGADVDGDATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADQSNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGGGGGSSSSSSGRRVGASAGSSSTSSSSSSGGGGTSSSSSTRNNNNNNNNNNNNNNSKSKTKKSGLDGSAAAAAATATATTTATTRATTTATVAAEATASSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00476771;
90% Identity
-
80% Identity
-