Basic Information

Insect: Drosophila pectinifera
Gene Symbol: ken1
Assembly: GCA_008042775.1
Location: VNKC01002367.1:32354-34613[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00046 0.032 14.5 3.3 2 23 200 221 199 221 0.97

2 12 0.015 1.1 9.7 0.1 1 23 227 252 227 252 0.90

3 12 0.011 0.74 10.2 0.1 3 23 261 284 259 284 0.93

4 12 0.00068 0.048 14.0 0.5 2 23 297 318 296 318 0.96

5 12 8.7e-06 0.00061 19.9 0.6 1 23 325 347 325 347 0.98

6 12 0.0052 0.36 11.2 0.1 1 23 353 375 353 375 0.98

7 12 0.014 0.99 9.8 4.0 1 23 381 404 381 404 0.97

8 12 0.0093 0.66 10.4 4.0 1 23 410 432 410 432 0.96

9 12 0.00079 0.056 13.8 2.9 2 23 439 460 438 460 0.96

10 12 0.00026 0.018 15.3 1.1 3 23 549 570 547 570 0.95

11 12 0.01 0.7 10.3 0.7 1 19 576 594 576 598 0.95

12 12 4.3e-06 0.0003 20.9 0.7 1 23 604 626 604 626 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00046	0.032	14.5	3.3	2	23	200	221	199	221	0.97
2	12	0.015	1.1	9.7	0.1	1	23	227	252	227	252	0.90
3	12	0.011	0.74	10.2	0.1	3	23	261	284	259	284	0.93
4	12	0.00068	0.048	14.0	0.5	2	23	297	318	296	318	0.96
5	12	8.7e-06	0.00061	19.9	0.6	1	23	325	347	325	347	0.98
6	12	0.0052	0.36	11.2	0.1	1	23	353	375	353	375	0.98
7	12	0.014	0.99	9.8	4.0	1	23	381	404	381	404	0.97
8	12	0.0093	0.66	10.4	4.0	1	23	410	432	410	432	0.96
9	12	0.00079	0.056	13.8	2.9	2	23	439	460	438	460	0.96
10	12	0.00026	0.018	15.3	1.1	3	23	549	570	547	570	0.95
11	12	0.01	0.7	10.3	0.7	1	19	576	594	576	598	0.95
12	12	4.3e-06	0.0003	20.9	0.7	1	23	604	626	604	626	0.98

Sequence Information

Coding Sequence: ATGGGCACCAGGGAGCCCCAGTACTCCGTCCACTCACTGTGTCGCACCTGCCTTGTCCACCTGGAGCACGGGAGAGGCCACGACTTGTTCCTGGTTCCAGATCTGGCCAAGAAACTGACTGTTTGCACATCAATGGAAGTAGATCCGCAGGATGGCTTTCCCAGCCACATCTGCCACCTGTGTTTTGGGAAGTTGATCGAGCTGCACGATTTCCAGGAGCAGTGTGCAAGTTCCCAAAAGCGCTATAAGGAGATGGTGGTCAATAACAAGGTTATCCCTGTTGGACAATTTGAGCCTGTGGCGGAGGAGGGCGAGACGCTGGgcaggcaggaggagcaggccagTTATGATCCTCTCCTGAACCACAAGCTGGAGATGATTGacaacgaggaggaggtgTTCAAGATGCTGGAAACGGTGGACATGGAACCGGAGGAGCATGTAAATTGCAATAACCAAGAGGATTCCTCCAGTGAAGAGGATGATCAGAATGAGCGGGATGAGGTGGAGGCACAAAAAAGCTTCTCCAGCGATGAACAACCCTTGGCTACGCGGAGAACGAATCCCTGCGCCGAACGCCACCTGCATCACCTTATCACATGTCCCATTTGCCAGCAGAAGTTCAAGAAGACGTCGAAGTACGAGGAGCACATGAAACACCATAATGACCTGCTCCCCTTTCAGTGCGCAGAGGAGAGCTGCCGAAAAGGCTTCACAACGGCGGGTGCCCTGCGGCTGCACGTTGACTACGCACACACCAAGAAGGCGAATGAGATTCCCTGCACCGTGGAGGGCTGCCGGTTGATGTTtccccgcctccgcctgctGACGATCCATCTGAAGAAGGTGCACAACCAGGCGAGAGTTAGTACTCCACGGGCAGATCAGCCGTGCGGAGAGTGCGGTATGGTTTTCCGCTGTCCGGTGGCCCTTAAGAAGCATATGTACAAGCACACTGGCGAGGAGCTTCCGTATCCCTGCAACATTTGCGGCAAGGGCTTCCACATCAACAGCGCATTGAAGAATCATCTCCTTCGGCACGCAGGCATCAAGAACTACGTGTGCCCGTACTGCGGGGTGGGAAAGACCACGAGGCAGGAGTGGAGCAAGCACATTCTCACGCACACCCAGGAAAAGCAGTTCAAGTGCCACATATGCGACCACGCCACCCACACGAAGCGCGCCTTGGACAGCCACGTGAAGATTGTGCACGAGAAGATCCGGAACTTTGCCTGTCAGTATTGCGGGAAGACCTTTGGCAAATCGCACGCCTGCAAGATACACGAGATGACGCATACGGGAGAAAAGCGGTGCGAGTGCAAGGTTTGTGGCAAGAAGTTCCTGTACACGGAGAGTCTGACGAAGCATCTTAAGATCCACGAAAAGAGCGTGGAAAGAGCTCTGGAAACCTATCGGCAACGACAGGGAGAGTGTGAGCCGGGGGAAGTCCAAGTGGATGCGGATCAACTCCTAAAAGTGTGCGCCGAATCCGTGGCCACCATTCCAAAAGATCCACGTCGCGTGGAGCGAGTTGATCTGTCACAACTTGCGGGCACAGTGGTGAATCCCATTCCCACAGTTCAAATGCCGCCCAGCGAGACGTCAACCCGCACGAAATTCGTCCAAAAGGAGGGCATGCACCTTTGCCCCGGCTGCAGCCAGGGATTCAATAACCTGGGGAATATGAAACGTCACTACAAGAGCGTCCATGAAAAGGTTAAGGACTTTGAGTGTCGTTTCTGCGCACGCCGCTTTGCCAACTCCCAGTCCCTGAAACAACACGAATGGATACACACGGGTGAAAAGCCGTACGAGTGCAAGGTGTGCGGCAATCATTTCCGGCAGGAGGCAGCTCTCATCCGACACCAAAAGGTCCATTTTGAAAAGCCACCCAAACCGCCGAAGCCACCTAAGGAAATCACCGATAAATCTCGCCAAAAAGCGTTGCAGAAGAGAGAACGGCGACAGAAAGTGGAGGCGCTCCGTCAGGAGATTGCAGAAGCTGCCAAGGAGGAACTGAAGGATCTGGAAAAGTTGCGTACCCTGGAGAGGCAAAAGAACAGCTACGAACAGTATCAGGCAGCTGCCGCTGTTCAAGCTAATCTTGAATCTGATTTGGACGATGAATCTTGA
Protein Sequence: MGTREPQYSVHSLCRTCLVHLEHGRGHDLFLVPDLAKKLTVCTSMEVDPQDGFPSHICHLCFGKLIELHDFQEQCASSQKRYKEMVVNNKVIPVGQFEPVAEEGETLGRQEEQASYDPLLNHKLEMIDNEEEVFKMLETVDMEPEEHVNCNNQEDSSSEEDDQNERDEVEAQKSFSSDEQPLATRRTNPCAERHLHHLITCPICQQKFKKTSKYEEHMKHHNDLLPFQCAEESCRKGFTTAGALRLHVDYAHTKKANEIPCTVEGCRLMFPRLRLLTIHLKKVHNQARVSTPRADQPCGECGMVFRCPVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKIRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGECEPGEVQVDADQLLKVCAESVATIPKDPRRVERVDLSQLAGTVVNPIPTVQMPPSETSTRTKFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYECKVCGNHFRQEAALIRHQKVHFEKPPKPPKPPKEITDKSRQKALQKRERRQKVEALRQEIAEAAKEELKDLEKLRTLERQKNSYEQYQAAAAVQANLESDLDDES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548237;
90% Identity: iTF_00606495;
80% Identity: -