Basic Information

Insect: Drosophila paulistorum
Gene Symbol: zfh1
Assembly: GCA_018152135.1
Location: JAECXG010000499.1:2473130-2480077[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2e-05 0.0015 18.9 1.3 1 23 144 166 144 166 0.97

2 15 0.00082 0.063 13.8 1.2 3 23 174 194 172 194 0.94

3 15 8.2e-05 0.0064 17.0 0.1 1 23 357 379 357 379 0.98

4 15 0.00062 0.048 14.2 0.8 1 23 385 407 385 407 0.98

5 15 0.00019 0.014 15.9 3.9 1 23 439 462 439 463 0.94

6 15 0.0016 0.12 12.9 0.9 1 23 491 513 491 513 0.95

7 15 0.011 0.88 10.2 1.6 1 23 519 542 519 542 0.97

8 15 0.026 2 9.1 0.4 3 19 551 567 550 568 0.95

9 15 0.00016 0.012 16.1 5.6 1 23 577 599 577 599 0.97

10 15 0.047 3.6 8.3 0.4 2 23 605 626 604 626 0.96

11 15 9.2e-06 0.00071 20.0 1.0 1 23 635 657 635 657 0.98

12 15 0.001 0.081 13.5 0.1 3 23 665 685 663 685 0.97

13 15 5.6e-05 0.0043 17.5 0.5 1 23 691 713 691 714 0.95

14 15 0.16 12 6.7 0.2 1 23 724 746 724 746 0.96

15 15 0.0056 0.44 11.2 0.2 1 23 1307 1329 1307 1329 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2e-05	0.0015	18.9	1.3	1	23	144	166	144	166	0.97
2	15	0.00082	0.063	13.8	1.2	3	23	174	194	172	194	0.94
3	15	8.2e-05	0.0064	17.0	0.1	1	23	357	379	357	379	0.98
4	15	0.00062	0.048	14.2	0.8	1	23	385	407	385	407	0.98
5	15	0.00019	0.014	15.9	3.9	1	23	439	462	439	463	0.94
6	15	0.0016	0.12	12.9	0.9	1	23	491	513	491	513	0.95
7	15	0.011	0.88	10.2	1.6	1	23	519	542	519	542	0.97
8	15	0.026	2	9.1	0.4	3	19	551	567	550	568	0.95
9	15	0.00016	0.012	16.1	5.6	1	23	577	599	577	599	0.97
10	15	0.047	3.6	8.3	0.4	2	23	605	626	604	626	0.96
11	15	9.2e-06	0.00071	20.0	1.0	1	23	635	657	635	657	0.98
12	15	0.001	0.081	13.5	0.1	3	23	665	685	663	685	0.97
13	15	5.6e-05	0.0043	17.5	0.5	1	23	691	713	691	714	0.95
14	15	0.16	12	6.7	0.2	1	23	724	746	724	746	0.96
15	15	0.0056	0.44	11.2	0.2	1	23	1307	1329	1307	1329	0.97

Sequence Information

Coding Sequence: ATGAACAATTCGAGCTATGGTAGATTCCAATGGATACAGCACCACGCCTCCGGCGACGAGACGGAGGCGGAAACCATAGTCGGAGGCGATGGTGAACCCGCAACTGCTTTTTTGGTGAATGGCACTACCCCGGACGAAGATCTCGATCATATGGCGGCCGAAAATCTAATTTTCATGGCACGCGATGGCCAGCTGGATGAAATTATAGCTGGTAATGATGCGGATTCGGGCGGTGCAGTGCTAGCCTACGCCTCGGACAAACCTTTCGATGATGAAGCCGAGGTGGTCACCGAAGAGGTCATTACTGATGACTGGGTCCAGCATCAGGGAGCGGAGAGGGTGGAAATTGCTGCAGAGCAAATAGCTGGTACCACAAGTTCCCAAGAGCTATTAGATATGGAGCAGGATGAATATACAGTGCTGCGTCCATATCCCTGTGATTTCTGCAGTCGCCGGTTTCGCAAAAAGGGCAGCCTCAACAATCATATGCAGGCCCATCAGAACGATCGACCGCATCTCTGCAAGCTGTGTGGCGCCCGCTTCTCACGTCGCGGGGAGCTGATTAGTCATTTTAAAGCCCATGCGGAGGCCCAGGATGCAGCCGATGCTGAAGCAGCAGCAGCGGCGGCCGCTGCTTCCGCCGCAGCAGCGCCGTCTTCGTTGTGTGCCTCCGTAAAGTATGAACAGCAACAGCAACGCCAACTGGATGATCACTACTACGAGCAGGATTGGCCCCTGTATCAGCAAGAGCAGAATCAAGAGCAGCAATGCTTAATCGTATCCAGCAGTGAGGTACCGCAACTGATGCAACAAACTAACTATATGACCGAAACCAACAGCAATGTGGCCACACCAGTGGCATCTGCATCTCGAGGCAGGATAAGTCGACTAAAGCCCAAAGAGGAGACCACCCAGTATATTGTGATTACCGAGAATGTGCAGAATGAACCGCCCCAGGGCCAGGTGGTGGCCACATCTACTTTAGTTGAACCGTCATCAGGCGTTGTGTCTGCCTCAGATCCTCCTGAACATCTTCTTAATTTCCCAGTCCTGGATGAGGGGAAACCATTTGTCTGTCAGGAATGTGGCTTAGCCTTTGCCCGTGAAAAGGCTCTGGTGTCTCATCTTAAGAATCATCGCGTGGACTCACCCTTTGAGTGCAACCAATGCCAGGAAATGTTCTGGGACAACAATAGCCTGCAGGAGCATCAGAAGACTCATCAGTTTGAGGAGAGTAACTCGGAATACGATCCGGCTTCAGCGTCAGATAGTGGCAGCGAATCGGAACAGGAGGATCAGCAGCTTTATGGTGAATTCTATTGCAACGAATGCGGCATTTCCTTTCACAGGCAGAATCTGCTACGTCGCCATGCCAAAGAGCAGCACCACAAGTCCGCCAATGGAACACATCCATCAGACAGCCATCAGCAGGAATTTGGTGAATTGGAAAACGGCACGGAAGGCTCTCCGCATTGTTGTCATACATGTGGCAAAGCTTATCCCAGCGCCATCGAGCTGCTTGCTCATGCAGAGATTCATGCCCGTTTTCCGCCCTTTAAGTGTGTCCTGTGTGGGATGAGTTTCTATGAGGAGCAAGCTATTAAGCGACATTTGCACACCCGCCATCCCCAAGAACTGAAGCCCAACTCGTGTGTGCTATGCGGCAAGGAGTGCCGCGATAGAAAGGCTCTCATCAAACACGCCTGGGACCATTCCCGTGAGAAGTGTCACTCCTGCTCCAAATGCGGCAAAAACTTTCACAACAAAGCCCGACTGAAGCGTCATATGGCATCTCATAGGGATAAATCGGTGGTCTGTGAGGTTTGCCAGGAAGAATTCCCCGATGGGCGAACTCTATCGAATCATCGACATTCACACAGCACCACTTCGCCGGGCAAACTGTTTCCCTGTCATGAGTGTGGAAAAACATTTGGCTCACGCAGCTCCCAGCAGATCCACGTACGTATCCACACGGGAGAACGTCCATATGGCTGTCGCTATTGCTGGAAAGCATTCGCCGATGGCGGAACCCTGCGCAAACATGAACGCATTCACACTGGCGAAAAGCCCTATGCCTGTTCGGTCTGTCCACGTGCCTTCAATCAGCGAGTGGTTCTTCGTGAGCATATTCGCTCCCATCATTCGGGTCTCGATGTAACAAAAGGAACCTATCACTGTACAGTCTGTTCGGCCGACTTACCCTCATCCAACGAGTTGATCCAGCATCTCATCCAGCATAGTGACTCGAACACGGCCAAGCAAAGAGCGCCCATTACTGGTCCGCGAAAATACAAACGTCGCCGCAAGTTACAGCCTCATGAAATAGCTCAAATGCGGGATGAGCACCAAGATGTTGAAACTGCCGGCGATGATGGTTTAGGGGAGGACGAGGGCGACGAGTATGCCACTGACATCGACATCTGTGACTTTGAATTGGAGAATGTGGATGATATCTTTGATATGGCTTCATCTACGCACACCAACAAAAAAGAAAGACGCAAGAAACCCGTCACAAAGGACACCAAACCAGTGCGCAATGGAACCGGGGCCAAGGGGCCGGATAAATCTACATCTAAACAGCGCTTTGATTCCAATAGTAGTCAATCGGAGCGTATGTGGGATGAGAAACTTTTGCAGGATAATCAAGCGGCCTTCTTTCAAATTGACTCGCTGGTGGTGGTTAACGATACCACTCTACAACCAGCTAGCTCTGTGAGTTGTTCCAACGGTGTGGGGAATGCGGCAAGGACGCGAAGAGCTGTCAAACAATCAGCCCAGACCAAACTTCCTCCGCCAGTTGATAGTAAAACCGATGTGATTGCCACTGCCGCAAGCTATGCCGCTTCTGGCAACACGAATAGCCGCAGCAAAAAGAAGACTACAAGCAAACCAAGTGCCTCCACCACCTCGCGTCCTCGAATGATACACACTGAAAAGACTAAGATGCCACGAGCCACGGCCACAGAGAGCTTGAATGGTGGTGGTGGTGTAGCGGCAGGAGTGGGCAGCACCAAAAGGACTCGTGCCAAGACCTATATAACGCGCACAGAGACCAACAATCTGGACTTGCTTGCGGGCGATGGCGGCAATCGTGCCAAAGCGAGTTCCACCGCCCCTGCGAATATTGTAGACGACTATGAGATCATTTCCCCTGCCACTCAACCTCCTAATCAGATAAGTTCCAGCCCACTGCATATAAAGCAAGAACAGGAGCAACAGCGTGTTCAGATGATGTACGACGATACGCTCCTGATTGATGCAGCACTTCTACGGGAGAAAACCTACGAAAAATACAATCCCAGCATTGTTAATGATTTGGAGGAGATTCTTCGGTCACCACTTAAAAACGATCGCAACACAAGTCGCCTGCGTTTCACCAGTGAGTCCTCTACAACTCCACAGTTCCTGCCCGGTGAGGAGCAAAACCTCATCAAGATTGAACCAACTTCACCCGATCTACGTGAAATGGTTGAGGGCCAACAGCGGATGACAAATTGTAATATTACGACTCCTACAACTTCCTCATCATCGTCGTCACCAGCAGCTTCCAATTCCCGGCACTTGCGTCAACTTACTGCCAACAGTCAGAGGACAGCAGGCAGCAAACGACCTAGCAGCAGCACCAGCACCTCCAGCAAAGCTGCATCCACAACTGCCTCAACGAGTTCCGCAAAGAAACCAGTTACTTCCTCATCCATAGTGGCCTCCAGCAAGGCCACCAGAAACACAGTCAGCAATTCCTATCTTAGCTATGGAGTTGGGGTAGACGCCTATAATGTGAATGTACCTGCCAATGCCAGCACTGCCGATGTGAATTCTGGTTTCTTCTCCATCTCCGAAGTTGTTTCCGCTGCCGAGACAGCCGATGCGGCAGCCAAAGAAGCGGCTGCCGGCAAAACGGAGCGAAAGACGCGAAGCTTTGAATGTGAAATGTGTTCGGCCATATTCTATGATCGAGCCCAACTGCTGGACCATGTTCACATTCACATTTAG
Protein Sequence: MNNSSYGRFQWIQHHASGDETEAETIVGGDGEPATAFLVNGTTPDEDLDHMAAENLIFMARDGQLDEIIAGNDADSGGAVLAYASDKPFDDEAEVVTEEVITDDWVQHQGAERVEIAAEQIAGTTSSQELLDMEQDEYTVLRPYPCDFCSRRFRKKGSLNNHMQAHQNDRPHLCKLCGARFSRRGELISHFKAHAEAQDAADAEAAAAAAAASAAAAPSSLCASVKYEQQQQRQLDDHYYEQDWPLYQQEQNQEQQCLIVSSSEVPQLMQQTNYMTETNSNVATPVASASRGRISRLKPKEETTQYIVITENVQNEPPQGQVVATSTLVEPSSGVVSASDPPEHLLNFPVLDEGKPFVCQECGLAFAREKALVSHLKNHRVDSPFECNQCQEMFWDNNSLQEHQKTHQFEESNSEYDPASASDSGSESEQEDQQLYGEFYCNECGISFHRQNLLRRHAKEQHHKSANGTHPSDSHQQEFGELENGTEGSPHCCHTCGKAYPSAIELLAHAEIHARFPPFKCVLCGMSFYEEQAIKRHLHTRHPQELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVTKGTYHCTVCSADLPSSNELIQHLIQHSDSNTAKQRAPITGPRKYKRRRKLQPHEIAQMRDEHQDVETAGDDGLGEDEGDEYATDIDICDFELENVDDIFDMASSTHTNKKERRKKPVTKDTKPVRNGTGAKGPDKSTSKQRFDSNSSQSERMWDEKLLQDNQAAFFQIDSLVVVNDTTLQPASSVSCSNGVGNAARTRRAVKQSAQTKLPPPVDSKTDVIATAASYAASGNTNSRSKKKTTSKPSASTTSRPRMIHTEKTKMPRATATESLNGGGGVAAGVGSTKRTRAKTYITRTETNNLDLLAGDGGNRAKASSTAPANIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQMMYDDTLLIDAALLREKTYEKYNPSIVNDLEEILRSPLKNDRNTSRLRFTSESSTTPQFLPGEEQNLIKIEPTSPDLREMVEGQQRMTNCNITTPTTSSSSSSPAASNSRHLRQLTANSQRTAGSKRPSSSTSTSSKAASTTASTSSAKKPVTSSSIVASSKATRNTVSNSYLSYGVGVDAYNVNVPANASTADVNSGFFSISEVVSAAETADAAAKEAAAGKTERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501217;
90% Identity: iTF_00503414;
80% Identity: -