Basic Information

Insect: Drosophila parvula
Gene Symbol: ZNF541
Assembly: GCA_018904695.1
Location: JAEIIG010004148.1:1-15687[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.037 2.8 8.6 1.7 2 23 191 212 190 212 0.97

2 6 3.4e-06 0.00026 21.3 1.3 1 23 218 240 218 240 0.98

3 6 0.00034 0.026 15.0 2.5 1 23 246 270 246 271 0.94

4 6 0.00057 0.043 14.3 0.8 2 23 549 570 548 570 0.97

5 6 0.95 72 4.2 0.0 1 16 1723 1740 1723 1741 0.93

6 6 0.13 9.6 6.9 1.1 1 11 1791 1801 1791 1804 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.037	2.8	8.6	1.7	2	23	191	212	190	212	0.97
2	6	3.4e-06	0.00026	21.3	1.3	1	23	218	240	218	240	0.98
3	6	0.00034	0.026	15.0	2.5	1	23	246	270	246	271	0.94
4	6	0.00057	0.043	14.3	0.8	2	23	549	570	548	570	0.97
5	6	0.95	72	4.2	0.0	1	16	1723	1740	1723	1741	0.93
6	6	0.13	9.6	6.9	1.1	1	11	1791	1801	1791	1804	0.88

Sequence Information

Coding Sequence: GTACCCAAGAGCATACACCTGCCATTGACCACTCTCAGCAGCAGCAGCAGCAGCAGCAGTGCGCCGCGCGTCTTGTTGTGCAGCGCCTCCGTGGGCACCGAGGGATCCGTGACTCTGCAACTGAGGGATGCCAACGCCTTGGAGGCAGCCACAGCCTCAGCCTCAAACGCAGCCTCGTCAAAGCCAGCGGGAACAGCGACAACAAGCGGTGGGGCAGCAACAGGAACAACGTCCACGAATGGCGCTGCAACAGCATCAGCGGCGACGCTAGAGAATGCTCTGACCATCGGCTATCCGGATCCGGAAATGCTAGCAGATGTTTTGGGCACCATTCAGACAGCCTCTCTTAAAAACCACAACAGCAACTCAATCACAGCAAGCAACGGACACGGCCACGGACACGGACACCACGGCAGACATGTGCCCGCTTCCGGCGGAGTAAGCACATCGGCGACAGCCACCAACACCAGCTCGGGTGGGATTGGAATCGGGATCGGTGGCATCATAAGCGTTGAAGCGCCACGCAAGAATCGACCCAAATTATCCTCACCGACGCGACACGGTCCGCAGCAGTGTCAGACTTGTTGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAACGGAAATACATCTGTGCGCTCTGCTCGAAGGCATTCAAGCGACAAGATCACTTAAACGGACACATGATGACTCATCGGAACAAGAAGCCTTACGAGTGTAAGGCGGATGGCTGCGGCAAGTCCTATTGCGACGCCCGCTCCCTGCGGCGTCACTCGGAGAATCACCATAACGGAGGTGCCACCACGCCCACCACCACCAGCCAGCAATCGTTGTCGCCCACCGCCAGCTCGAGCGGAGCGAGCAGCAGCAGCGTCGGCGTGGCCACCAGCTCGCTGAGTCTCTCGCCGGCCACGGCCAGCGGGGATGCCAGCTCTCCGGACGGTGCCACCTGCATTCGCACCTACATCTCCACGGGCAGCTCGGTGGTGGACGCGGCCACCGGCATCGCTTTGTCGGACGAGCAGATCAAGGCCATGAACCTGCCGATCAAGACGGGCGTGACTCTGTTATCGCCCACCACCTCGACATCGTCAAATGCCTCCTCAACGGCATCCTCGTCGTCATCCTCCGCCTCCGCCTCTGTCTCGTCACTGTCCTCGGCGACATCTGGAATGGGTTTGACGGCGGTTTCCTCGCCTTCTGGCGGCGGCGGCGGCGGGACCGTGATAGCCACCAGTTCGCCAGCGCCAACTATTACGCTCAGCGATGGAATGACCCTTGAGGGCGAGGGCCTGACCCGAGAGCAACTGGACCTCATCAGCAAGATTATGCAGCAGACGAAGCAGACAAGCGCCCAGGTCACTGTCTCCTCGCCCACCAGCGTCAGCTCCTACAAGATCAACACGAACTCGGCGCCGTCGCAGGCCAGACCGCGCACTTGGAACATGCAATTGCTGAACAGCGCCCAGAATGTGACGGTCACCGTTGAGGAGAACAGCGAACTGGTGGCTCCCTGCTCCAGCTCCCCCGTGGAGATCAAGGAGGAGGAGCTAAGTCCGCAGCTAGTGGCCGCCATCAATCCCCACCTGCTCAACATTGTGAAGCTCGACAAGCCCGTCGAGTGTAATCTGTGTCACCGCAAGTTCAAAAACATACCCGCCCTAAACGGGCATATGCGTCTCCATGGAGGCTACTACAAGAAGGATCCGGAAACTAAGCGGAGCGAGAAGAAGGACTCCAATGGACCGCCCCTGCAGACGGCCAGCATTGGAGTGCGTGCCCTCATCGAGGAGAAGATCATCAGCAAGCGAAAGGACATGACGAAGGGCTCCTTTGTGGTTCCCGCACCACCGCACAGCAGCGGCACCACCACCACCCTGCGTCGATCCATCAGCGACCTGGAGAGCTTCCTCAATCCGAAGAACAGCTCGAGCGGCCACACACAGACCCTAAACACCGGCGCGGGCACCACCACGGCGGTCCTGCCAGCGGCCACCACCATTAAGAGCAGCAACGGGCTGAGCATCCAACAGATTGGTCTGCCGCAGAGTATCGAGATCTTCAGTGGCGGCCAGAAGCAGGCAAAGACCCTCAATCTGGGCAGTGGCACGAATACCATCACTATAACTACCAACAATGTGCCCACCACCACGACGATGAGTGCGTTGACTGCCTTAAAGGCCGGCGGCACTATCAGCGGCATTTCTACGGCAACCAACACAGATCCCAAGGACTCCACGCTGATTGAGCTCCTGAAGCGAGGCACCCGCATTGCAGTCACCTCGAAGAAGGCCCAGGCTCAGGCGCAGTGTCAAACGACAACCGGTGTCCTGATGACCTCCAGTGGCACGGCCACGCAATCAATGGGCACCCTCACCGAGCTGACCACGATTGGCGGCAACAGTAGTGTCCAGACGGTGGGCCGCCAAATCATCACGAACAACAATCGCACCGTGATCATACCCTCCGACGTCCAGGTGGTGTCCACCAAGAGCAAGCTGAGCAGCCTCACCAGTCTGAGCAGTCTGAGTAGTCTGAGTAGCCTGAGCAGTCTGAGCAGTCTGGTGAAGAGCACCAGCACCAGCACCAGCACCAGTTCCACCAATACCAGCTGCTCCTCGGGTAATCTCTCGCTGGCAGACGGTACTCCGCTCTCGCTCACTATAGCGCCCAGCCAGGATGTGTCTGGTGCTGCTACTGGTGGTGTTCCGAGTGGGACAGGCAGTGTGATCACCAGCGGTGGCGGCGGCGTCTACACGGTGACCTATACCAGTGACGGCACCGATCTCTTTGACGACGCCGAAGTGTACAATGTGTCCGACACGGAGATGCTGCTGCAGACGGTGGACTCGATGGAGCTGCTCAACGATGACGAGGAGGAGCCGCAGATCAAGAGGGAACATTCCGAGGACTTTGCCATGCTGAGCGAGACCGGCGACAGTGCCCACACCCAGCTCGTAAAGCTGGAGCCGGAGAGCGGGCAGGCTGGCGGCGGCTCCAACTCCTCGGGAGGAGGAGCAGGAGCGGGAGCCAACACAACGCCGCTGCCCACCTTCCAGCAATTCCATTCCAAGGAGCTGATCATGCAGAACAGTTCGCAGATCCAGGCCATAGCCAGCATGCGGGCAACCGGAAATGGTAATGGTAGCGGTAATGGTAATGGTAATGGCAATGGCACTGTCCTGGCCTCGCCGCTTCACTCGCCGCTGGCTTATCCCACGCCGCCTTCGAGCCACGAGAACATGGCTCAGAGCTCGCCGTTTATTGAGGACGCGGCCGCCCAGTTCGTGGACGCCAGCAACACCTTCTTCGGCGACAAGACGGACTTCTCGCACATCTACTTTAAGACGGACGAGGGTCAGGCCACCATCGAGCAGATGAACGAGCATGACAACGAGAAGATCCTCAAGCTCAAGTCGGTGCTGGAGGAGAGCAGCTTCGATCCCTCCATCAAGGTGGAAGACCTGCTCAACGGCACCGACGACGACACCGAGTGTGATCTTCGAGAGTTTGCGGAGACGAATCTCTCGTTTCTGGACGAGGATCAGGAGTTCCTCAACGACTCTCGTAATGCCACCTCCCCGCTGTCGGAGTCCTTCTTCACCAGCGGCATTGGCTCGGCGGAGGATGTAAAGCAGGTACTGCGCGAAGTCCTGCCGGATGAGAATATGCAGCTGCAGCTGACCAGCGAGCAGCAGGGCGAGAATATCATCGATCTCTACTATCTGCCGGGCCTGGGACTGCAATCCCAGATGATGCCCAACTCGGAGGACCCCTTGCTATCCTCCTCGCCCCGGGAGTTTGGCCAGCAGCGGCCGCAGATGAGCAGCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATCCTGTTGCCCCAGCAAGCGGCTAATCAAGGGGAATCCCTGCCAGCGGTGGTACAGCAGCAGGCCGACTTCATGATGCCACTGGTGGGAGGACATGGCTTTACCCAGGTCTCTTCCGGCCAGGCCCAATACGTGGACAATGGCCAGGGTAACATGCAAGGGATGCAGCCTCTCAACAATCTTCTGCAGCCGTTGCTCTACCAAGGAACAGTTGCCGCCGGGGGACAAGCGGGCCTGCTGCCCACCGATTGCCAAATGAATGCCAATCAGAACCAGACAACGACTACCCTGGATGCCGGCCTGTTGTTCGCCTGCGGCAACACCACCTCGGCTACAGCCACATCGATGGGCAATAAATCCCTGCTAGCCTCAGGGCCTCTGCCCGGCTCGGTGGCCAATCTCCAGCCGCTGTCGAACCAAACCAATTCCATTCTGAAGCGCCGCCTGCGCTCCAGTGCGCCCCAGGAGACCCACAAGTTCTCCAAGTTCCACACTCTGTCGCCGCACCGCTCCAAGCTGAGGAAACCGTCTCGCACCCATTATACACCTGGTCCGATCCTGAATCCGGACCGCAAGGGCACCGGCCTCTACAGCAGCGTCCGCAAGCAGATGGGCCTGGCTCAGGGCCTCTTCGATGGCTTCGACGATGACTTCGGTGATCCGGTGGGCCTGGTCGACTTCTCCGACGAGTCTAAGGTGAATCTTGGTTCCACCTACCAGGCGCAGATACCAAGCTGCCGGCTGCCGGAGGAGGCTATGCGAGATCCACTCGGTGCGGAGATGATGTGGAATCCGGAGGTGCAGGAGGACGAGAAGATCCTGATGCGCTACATTGATCTCAGCAAATCATCGGCCGTGCCCATGGGCAGTCATTCCGAGGAGGTGGCCCTCCACACGCTGCTCAAGGCCAGGGGCAACTCGGCGGCAGCGGTGCTCAGCCTGCTGCAGACGCAATCCGGCGCCTTCCAGATGAAGTGGTCGGCCTACGAGCTGGAGCAGTTCCTGCGCGGTCTAGAGAAGCACGGCAAGGACTTTGGCAAGATTGCCAGCGAGCTCCTCACCAAGTCCTCTGGGGACTGTGTGCAGATGTACTACTTCTGGAAGAAGCTGTGCGTGGATTATAAGGTGTCGCACCTCAAGATGGAGCCGGTTGTGGTGATCACGCCCGCCGTGGAGAAGCCCTATGTCTGCGAGATTGCCGACTGCTCAGCGAGCTTCAGTTCGAAGGCGGCGCTGCACGGAGCCGCAGGAGCCACACACGGTGGCAATTGCAATCAGAATCCTGGCGCCACGACTGGAGCTGTTGCCGCCTCCGCGGCGACCACGGCCACGTCCAAGCCGGAACAGGGAATTAACGCCATACCAGGTGCCGCCAAGGAGGGCGAGTTTCCCTGCAAGGTGTGCGGCAAGGTCTTCAATAAGACTACAGCAGGGCTGCCCACACAGAGCACTTGCGAGCACACGAAGCTGGAGTACTCTGTGCGGGCAGCTCTGCCTTGA
Protein Sequence: VPKSIHLPLTTLSSSSSSSSAPRVLLCSASVGTEGSVTLQLRDANALEAATASASNAASSKPAGTATTSGGAATGTTSTNGAATASAATLENALTIGYPDPEMLADVLGTIQTASLKNHNSNSITASNGHGHGHGHHGRHVPASGGVSTSATATNTSSGGIGIGIGGIISVEAPRKNRPKLSSPTRHGPQQCQTCCKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHNGGATTPTTTSQQSLSPTASSSGASSSSVGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSSSSASASVSSLSSATSGMGLTAVSSPSGGGGGGTVIATSSPAPTITLSDGMTLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTNSAPSQARPRTWNMQLLNSAQNVTVTVEENSELVAPCSSSPVEIKEEELSPQLVAAINPHLLNIVKLDKPVECNLCHRKFKNIPALNGHMRLHGGYYKKDPETKRSEKKDSNGPPLQTASIGVRALIEEKIISKRKDMTKGSFVVPAPPHSSGTTTTLRRSISDLESFLNPKNSSSGHTQTLNTGAGTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGQKQAKTLNLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTATNTDPKDSTLIELLKRGTRIAVTSKKAQAQAQCQTTTGVLMTSSGTATQSMGTLTELTTIGGNSSVQTVGRQIITNNNRTVIIPSDVQVVSTKSKLSSLTSLSSLSSLSSLSSLSSLVKSTSTSTSTSSTNTSCSSGNLSLADGTPLSLTIAPSQDVSGAATGGVPSGTGSVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSMELLNDDEEEPQIKREHSEDFAMLSETGDSAHTQLVKLEPESGQAGGGSNSSGGGAGAGANTTPLPTFQQFHSKELIMQNSSQIQAIASMRATGNGNGSGNGNGNGNGTVLASPLHSPLAYPTPPSSHENMAQSSPFIEDAAAQFVDASNTFFGDKTDFSHIYFKTDEGQATIEQMNEHDNEKILKLKSVLEESSFDPSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSEDPLLSSSPREFGQQRPQMSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXILLPQQAANQGESLPAVVQQQADFMMPLVGGHGFTQVSSGQAQYVDNGQGNMQGMQPLNNLLQPLLYQGTVAAGGQAGLLPTDCQMNANQNQTTTTLDAGLLFACGNTTSATATSMGNKSLLASGPLPGSVANLQPLSNQTNSILKRRLRSSAPQETHKFSKFHTLSPHRSKLRKPSRTHYTPGPILNPDRKGTGLYSSVRKQMGLAQGLFDGFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPSCRLPEEAMRDPLGAEMMWNPEVQEDEKILMRYIDLSKSSAVPMGSHSEEVALHTLLKARGNSAAAVLSLLQTQSGAFQMKWSAYELEQFLRGLEKHGKDFGKIASELLTKSSGDCVQMYYFWKKLCVDYKVSHLKMEPVVVITPAVEKPYVCEIADCSASFSSKAALHGAAGATHGGNCNQNPGATTGAVAASAATTATSKPEQGINAIPGAAKEGEFPCKVCGKVFNKTTAGLPTQSTCEHTKLEYSVRAALP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00572137;
90% Identity: iTF_00569628; iTF_00525820; iTF_00526146;
80% Identity: iTF_00569628;