Basic Information

Insect: Drosophila kanapiae
Gene Symbol: Trerf1_2
Assembly: GCA_008042475.1
Location: VNJM01002139.1:937805-947843[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.038 3 8.5 1.7 2 23 191 212 190 212 0.97

2 6 3.5e-06 0.00028 21.2 1.3 1 23 218 240 218 240 0.98

3 6 0.00035 0.028 14.9 2.5 1 23 246 270 246 271 0.94

4 6 3.7 3e+02 2.2 0.5 7 23 553 569 548 569 0.91

5 6 0.0016 0.13 12.8 0.1 1 23 1718 1742 1718 1742 0.98

6 6 7.9e-05 0.0063 17.0 0.8 1 23 1869 1891 1869 1891 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.038	3	8.5	1.7	2	23	191	212	190	212	0.97
2	6	3.5e-06	0.00028	21.2	1.3	1	23	218	240	218	240	0.98
3	6	0.00035	0.028	14.9	2.5	1	23	246	270	246	271	0.94
4	6	3.7	3e+02	2.2	0.5	7	23	553	569	548	569	0.91
5	6	0.0016	0.13	12.8	0.1	1	23	1718	1742	1718	1742	0.98
6	6	7.9e-05	0.0063	17.0	0.8	1	23	1869	1891	1869	1891	0.98

Sequence Information

Coding Sequence: ATGAACTATCATCTATTGTGTATCTCGCAGGTACCCAAGAGCATACACCTGCCATTGACCActctcagcagcagcagcagcagcagcagcagcgcgccGCGCGTCTTGTTGTGCAGCGCCTCCGTGGGCACCGAGGGATCCGTGACTCTGCAACTGAGGGATGCCAACGCCTTGGAGGCAGCCACAGCCTCAGCTTCGAACGCAGCCTCGTCAAAGCCAGCGGGAACGGCGACAACAAGCGggggagcagcaacagcaacgtccACGAATGGCGCTGCAACAGCGTCAGCGGCGACGCTAGAGAATGCGCTGACCATCGGCTATCCGGATCCGGAAATGCTAGCAGATGTCTTGGGCACCATTCAGACAGCCTCTCTTAAAAACCACAACAGCAACTCAATCACAGCAGTAACTTCAAGCAATATCTCGGCCAAATCGGCCCTAGGCAATCATTTGACCACCAACACCAGCTCGGGTGGGATTGGAATCGGGATCGGTGGTATCATTAGCGTTGAAGCGCCGCGCAAGAATCGACCCAAATTATCCTCACCGACGCGACACGGTCCGCAGCAGTGTCAGACTTGTTGCAAGATCTTTGGAAATGCCTCGGCGCTGGCCAAGCACAAACTGACGCACAGCGACGAGCGGAAATACATCTGTGCGCTCTGCTCGAAGGCATTCAAGCGACAAGATCACTTAAACGGACACATGATGACTCATCGGAACAAGAAGCCTTACGAGTGTAAGGCGGATGGCTGCGGCAAGTCCTATTGCGACGCTCGCTCCCTGCGGCGTCACTCGGAGAATCATCATAACGGAGGAGCCACCACGCCAACCACCACCAGCCAGCAATCGCTGTCGCCCACCGCCAGCTCGAGCggagcaagcagcagcagcgtcggcGTGGCCACCAGCTCGCTGAGTCTCTCGCCGGCCACGGCTAGCGGGGATGCCAGCTCCCCGGACGGTGCCACCTGCATTCGCACCTACATCTCCACGGGCAGCTCGGTGGTGGACGCGGCCACCGGCATCGCCTTGTCGGATGAGCAGATCAAGGCCATGAACCTGCCAATCAAGACGGGCGTAACTCTGCTATCGCCTACCACCTCGACATCGTCAAATGCCTCCTCAACGgcatcctcgtcatcgtcctccgcctccgcctctgtCTCGTCACTGTCCTCGGCGACATCTGGAATGGGTTTGACGGCGGTTTCCTCGCCTTCtagcggcggtggtggcaccGTTATAGCCACCAGTTCGCCAGCGCCAACTATTACGCTCAGCGATGGAATGACCCTTGAGGGCGAGGGCCTGACCCGAGAGCAGCTGGACCTCATCAGCAAGATCATGCAGCAGACGAAGCAGACGAGCGCCCAGGTTACCGTCTCCTCGCCCACCAGCGTCAGCTCCTACAAGATCAACACGAACTCGGCGCCGTCGCAGGCCAGACCGCGCACTTGGAACATGCAATTGTTGAACAGCGCCCAGAATGTGACGGTCACCGTTGAGGACAACAGCGAACTGGTGGCTCCCTGCTCCAGCTCACCCGTGGAgatcaaggaggaggagctaaGTCCGCAGTTAGTGGCCGCCATCAATCCCCACCTGCTCAACATTGTTAAGCTTGATAAGCCCGTTGAATGTAATCTGCGTCACCGCAAGTTCAAAAACATACCCGCCCTTAACGGGCACATGCGTCTCCATGGAGGCTATTACAAGAAGGATCCGGAAACCAAGCGGAGCGAGAAAAAGGACTCCAATGGACCGCCCCTGCAGACGGCCAGCATCGGTGTGCGTGCCCTCATCGAGGAGAAGATTATCAGCAAGCGAAAGGACATGACGAAGGGCTCCTTTGTGGTTCCCGCACCACCgcacagcagcggcaccaccaccaccctgCGTCGATCCATCAGCGACCTGGAGAGTTTCCTCAATCCGAAGAACAGCTCTAGTGGCCACACACAGACCCTGACCACCGGCACGGGCACCACCACGGCGGTACTGCCAGCGGCCACCACCATTAAGAGCAGCAACGGGCTGAGCATCCAACAGATCGGTCTGCCGCAGAGCATCGAGATCTTCAGCGGCGGCCAGAAGCAGGCAAAGACCCTCAACTTGGGCAGCGGCACGAATACCATCACTATAACTACCAACAATGTGCCCACCACCACAACGATGAGTGCGCTGACTGCCTTAAAGGCTGGCGGCACAATTAGCGGCATTTCTACGGCCACCAATACGGATCCCAAGGACTCCACGCTGATCGAGCTCCTGAAGCGAGGCACCCGCATTGCAGTCACCTCGAAAAAGGCCCAGGCTCAGGCGCAGAGTCAAACGACAACCGGTGTCCTGATGACCTCCAGTGGCACGGCCACACAATCAATGGGCACCCTCACTGAGCTGACCACGATTGGCGGTAGCAGCAGTGTCCAGACGGTGGGTCGCCAGATCATCACAAACAACAATCGCACCGTGATCATACCCTCCGACGTCCAGGTGGTGTCCACCAAGAGCAAGCTGAGCAGCCTGACCAGTCTGAGCAGTCTGAGTAGTCTAAGTAGCCTGAGCAGTCTGAGCAGTCTGGTGAagagcaccagcaccagcaccagttCCACCAATACGACCTGCTCCTCGGGTAATCTCTCGTTGGCAGACGGTACACCGCTCTCGCTCACTATAGCGCCCAGTCAGGATGTGTCTGGTGCTGCTACTGGTGGTGTTCCGAGCGGGACAGGCAGCGTGATTAccagcggtggcggcggcgtctACACGGTGACCTACACCAGCGACGGCACCGATCTCTTCGACGACGCCGAGGTGTACAATGTGTCCGACAcggagatgctgctgcagaCGGTGGACTCGATGGAGCTGCTcaacgacgacgaggaggagccggaGATCAAGAGGGAACATTCCGAGGACTTTGCCATGCTGAGCGAGACCGGCGACAGTGCCCACACCCAGCTCGTGAAGCTGGAGGCGGAGAGCGGGCAGGCCGGCGGCGGCTCAAACTCctcaggaggaggagcaggagcgggagccaACACCACGCCGCTGCCCACCTTCCAGCAATTCCATTCCAAGGAGCTGATCATGCAGAACAGTTCGCAGATCCAGGCCATAGCCAGCATGCGGGCAACCGGAaatggtaatggtaatggcaatggcaatggcactgTCCTGGCCTCGCCGCTCCACTCGCCGCTGGCGTATCCCACGCCACCTTCGAGCCACGAGAACATGGCTCAGAGCTCGCCGTTTATTGAGGATGCGGCCGCCCAGTTTGTGGATGCTAGCAACACCTTCTTCGGCGACAAGACGGACTTCTCGCACATCTACTTTAAGACGGACGAGGGCCAGGCCACCATCGAGCAGATGAACGAGCACGACAACGAGAAGATCCTTAAGCTCAAGTCGGTGCTGGAGGAGAGCAGTTTCGATCCCTCGATCAAGGTGGAGGACCTGCTCAACGGCACCGACGACGACACCGAGTGTGATCTACGGGAATTTGCGGAGACGAATCTCTCGTTTCTGGACGAGGACCAGGAGTTCCTCAACGATTCCCGTAATGCCACCTCCCCGCTCTCGGAGTCCTTCTTTACCAGCGGCATTGGCTCGGCTGAGGATGTAAAGCAGGTCCTGCGCGAAGTCCTGCCGGATGAGAatatgcagctgcagctgaccAGCGAGCAGCAGGGCGAGAACATCATCGATCTCTACTATCTGCCGGGCCTGGGACTGCAGTCCCAGATGATGCCCAACTCGGAGGACCCCTTGCTGTCCTCCTCGCCCAGGGAGTTTGGCCAGCAGCGGCCGCAGATGAGCAGCATGCAGCCCCTGGAGCAACAGCTCCAGCAGAATGGCAACCTttatcagcagcaggagcagcagcaacaacagcagctccaGGAGCAACCCCAGCAGGAGCaatcacagcagcagcagcagcaacaataccAGCAGATCCTGTTGCCCCAGCAAGCGGCTAATCAAGGGGAATCCCTGCCAGCGGTGGTACAGCAGCAGACCGATTTCATGATGCCCCTGGTGGGAGGACATGGCTTCACCCAGGTCTCTGCCGGCCAGGCCCAATACGTGGACAATGGCCAGGGTAACATGCAAGGCATGCAGCCACTCAACAATCTTTTGCAACCGCTGCTCTATCAAGGAACAGTTGCCGCCGGCGGACAAGCGAGCCTGCTGCCCACCGATTGCCAAATGAATGCCAATCAGAATCAGACAACGACTACCCTGGATGCCGGCCTGCTGTTCGCCTGCGGCAACACCACCTCTGCTACAGCCACATCGATGGGCAATAAATCCCTGCTAGCCTCAGGCCCTCTGCCCGGCTCGGTGGCCAATCTGCAGCCGCTGTCGAACCAAACCAATTCCATTCTGAAGCGCCGCCTGCGCTCCAGTGCGCCCCAGGAGACCCAGAAGTTCTCAAAGTTCCACACATTGTCGCCGCACCGCTCCAAGCTGAGGAAGCCCTCTCGCACGCATTATACGCCTGGACCGATCCTAAATCCGGACCGTAAGGGCACCGGCCTCTACAGCAGCGTCCGCAAGCAGATGGGCCTGGCCCAGGGTCTCTTCGATGGCTTCGACGACGATTTCGGTGATCCGGTGGGCCTGGTCGACTTCTCCGACGAGTCCAAGGTGAATCTTGGTTCCACCTACCAGGCGCAAATACCCAGCTGCCGGCTGCCGGAGGAGGCTATGCGAGATCCACTCGGCGCGGAGATGATGTGGAATCCGGAGGTGCAGGAGGACGAGAAGATCCTGATGCGCTACATTGATCTCAGCAAGTCGTCGGCCGTGCCCATGGGCAGTCATTCCGAGGAGGTGGCCCTCCACACGCTACTCAAGGCCAGGGGCAACTCGGCGGCAGCGGTGCTCAGCCTGCTGCAGACGCAATCCGGCGCCTTCCAGATGAAGTGGTCGGCCTACGAGTTGGAGCAGTTCCTGCGCGGTCTGGAGAAGCACGGCAAGGACTTTGGCAAGATAGCCAGCGAGCTCCTGACAAAGTCCTCTGGGGACTGTGTGCAGATGTACTACTTCTGGAAGAAGCTGTGCGTGGACTACAAGGTGTCGCACCTCAAAATGGAGCCGGTTGTGGTGATCACGCCCGCCGTGGAGAAGCCCTATGTCTGCGAGATTGCCGACTGCTCAGCGAGCTTCAGTTCGAAGGCGGCGCTGCACGGTCATGTCCGCATTCACGCTTATGGTCGCAAcaacagtagcaacaacaccagcaatagcaacaacaatggcagcagcaacaataaccaGCATGCCACGGCCACTAATGTCAATAGTAGCAGCAAtacgaacaacaacagcagcagcggcaacaccaacagcaacggcaacatcaacggcagcagcaacagcaactatGCCAGCAATAGTAGTAGCAACAACACCGCCAGCAATGTAGCAACTGCCACAGGAGCCGCAGGAGCCACACACGGTGGCAATTGCAATCAGAATCCTGGCGCCACgactggagctgctgccgcctccaCGGCGACTACGGCCACGTCCAAGCCGGAACAGGGAATTAACGCCATACCAGGTGCCGCCAAGGAGGGCGAGTTTCCCTGCAAGGTGTGCGGCAAGGTCTTCAATAAGGTGAAGAGTCGCAGTGCGCATATGAAGACCCATCGTGTCCAGGAGCCGGATCAAAAGCACCAGCAACAAAATCATCagacgacagcagcagcagcagcagcaggagcaggatcagCTGGATCAGGACTGGCGACCGTGACCCCATCAAGCATCACCACTTCGTCGTAG
Protein Sequence: MNYHLLCISQVPKSIHLPLTTLSSSSSSSSSAPRVLLCSASVGTEGSVTLQLRDANALEAATASASNAASSKPAGTATTSGGAATATSTNGAATASAATLENALTIGYPDPEMLADVLGTIQTASLKNHNSNSITAVTSSNISAKSALGNHLTTNTSSGGIGIGIGGIISVEAPRKNRPKLSSPTRHGPQQCQTCCKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECKADGCGKSYCDARSLRRHSENHHNGGATTPTTTSQQSLSPTASSSGASSSSVGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSVVDAATGIALSDEQIKAMNLPIKTGVTLLSPTTSTSSNASSTASSSSSSASASVSSLSSATSGMGLTAVSSPSSGGGGTVIATSSPAPTITLSDGMTLEGEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTNSAPSQARPRTWNMQLLNSAQNVTVTVEDNSELVAPCSSSPVEIKEEELSPQLVAAINPHLLNIVKLDKPVECNLRHRKFKNIPALNGHMRLHGGYYKKDPETKRSEKKDSNGPPLQTASIGVRALIEEKIISKRKDMTKGSFVVPAPPHSSGTTTTLRRSISDLESFLNPKNSSSGHTQTLTTGTGTTTAVLPAATTIKSSNGLSIQQIGLPQSIEIFSGGQKQAKTLNLGSGTNTITITTNNVPTTTTMSALTALKAGGTISGISTATNTDPKDSTLIELLKRGTRIAVTSKKAQAQAQSQTTTGVLMTSSGTATQSMGTLTELTTIGGSSSVQTVGRQIITNNNRTVIIPSDVQVVSTKSKLSSLTSLSSLSSLSSLSSLSSLVKSTSTSTSSTNTTCSSGNLSLADGTPLSLTIAPSQDVSGAATGGVPSGTGSVITSGGGGVYTVTYTSDGTDLFDDAEVYNVSDTEMLLQTVDSMELLNDDEEEPEIKREHSEDFAMLSETGDSAHTQLVKLEAESGQAGGGSNSSGGGAGAGANTTPLPTFQQFHSKELIMQNSSQIQAIASMRATGNGNGNGNGNGTVLASPLHSPLAYPTPPSSHENMAQSSPFIEDAAAQFVDASNTFFGDKTDFSHIYFKTDEGQATIEQMNEHDNEKILKLKSVLEESSFDPSIKVEDLLNGTDDDTECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLTSEQQGENIIDLYYLPGLGLQSQMMPNSEDPLLSSSPREFGQQRPQMSSMQPLEQQLQQNGNLYQQQEQQQQQQLQEQPQQEQSQQQQQQQYQQILLPQQAANQGESLPAVVQQQTDFMMPLVGGHGFTQVSAGQAQYVDNGQGNMQGMQPLNNLLQPLLYQGTVAAGGQASLLPTDCQMNANQNQTTTTLDAGLLFACGNTTSATATSMGNKSLLASGPLPGSVANLQPLSNQTNSILKRRLRSSAPQETQKFSKFHTLSPHRSKLRKPSRTHYTPGPILNPDRKGTGLYSSVRKQMGLAQGLFDGFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPSCRLPEEAMRDPLGAEMMWNPEVQEDEKILMRYIDLSKSSAVPMGSHSEEVALHTLLKARGNSAAAVLSLLQTQSGAFQMKWSAYELEQFLRGLEKHGKDFGKIASELLTKSSGDCVQMYYFWKKLCVDYKVSHLKMEPVVVITPAVEKPYVCEIADCSASFSSKAALHGHVRIHAYGRNNSSNNTSNSNNNGSSNNNQHATATNVNSSSNTNNNSSSGNTNSNGNINGSSNSNYASNSSSNNTASNVATATGAAGATHGGNCNQNPGATTGAAAASTATTATSKPEQGINAIPGAAKEGEFPCKVCGKVFNKVKSRSAHMKTHRVQEPDQKHQQQNHQTTAAAAAAGAGSAGSGLATVTPSSITTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00572137;
90% Identity: iTF_00569979;
80% Identity: iTF_00525820;