Dpav016002.1
Basic Information
- Insect
- Drosophila parvula
- Gene Symbol
- -
- Assembly
- GCA_018904695.1
- Location
- JAEIIG010031726.1:49647-53445[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.11 8.1 7.1 4.9 2 23 341 363 340 363 0.95 2 17 0.05 3.8 8.2 0.1 1 23 370 395 370 395 0.94 3 17 0.033 2.5 8.8 2.2 2 23 406 427 406 427 0.93 4 17 0.042 3.2 8.4 0.1 3 23 468 489 467 489 0.95 5 17 0.0041 0.31 11.6 0.3 3 23 497 517 495 517 0.95 6 17 0.043 3.3 8.4 0.7 1 23 525 548 525 548 0.97 7 17 0.0059 0.44 11.1 0.3 2 23 553 574 552 574 0.97 8 17 0.0022 0.17 12.4 0.5 1 22 622 643 622 646 0.90 9 17 0.34 26 5.6 1.4 3 21 653 671 653 672 0.90 10 17 0.0026 0.19 12.2 0.9 1 23 691 716 691 716 0.96 11 17 0.15 11 6.7 1.3 2 23 734 756 733 756 0.94 12 17 0.017 1.3 9.7 0.5 2 23 762 784 761 784 0.92 13 17 0.017 1.3 9.7 0.2 2 23 788 810 787 810 0.95 14 17 3.2e-05 0.0024 18.3 0.6 1 23 816 838 816 838 0.97 15 17 0.0083 0.63 10.6 0.9 1 23 842 865 842 865 0.93 16 17 8.2e-06 0.00062 20.1 1.4 1 23 871 894 871 894 0.97 17 17 5.7e-05 0.0043 17.4 0.2 5 23 907 926 898 926 0.90
Sequence Information
- Coding Sequence
- ATGTCGGAAAACCAGAAAAACAATAGCTGCCTGCATTGTAGTGTTTTCAATACGAAATACCGGTACCAGGAGATCTTTGATGAGTTTGGCGCGGAGCTGGGCCTGCAATCGTTGCTGGCCAAGCACTTTCAGCTGAATGTGGAACCCGATCCGCAGCAGCGTCAGCTTCTGTGCGAGGTTTGCGTCAACACGCTCATCCGGCTGTTCGATATCGATGAATTGCAACGGCAACGGGATGCGGCGAGGGGTGGTAGGATCAAACATTCCAGCCCGCAGCCCCACCAACAAACTGTTGTCAATCCGGTTGCAGTCAAGGTTCCGCCAGCTGTAGCTAAGCCTGCTCCTCCTGCTACTGATGCTCCCAAAAGGGCGAAGATTCTTAAGCCCGTAGTGGTTGCTCCTCCTCCTGTTCCTTCCATCAGGGAACCAAGTGCACGGATTTGCAAGAGAGTTGCGCCACCTCCAGTATTGCCGGCTGCATCTAAGCCATCTGGTAAAGTGAATGAGTGTGCAAAGCCTGCCAAGGAGCCTGTGAAGCCTGCCAAGGAGGCATCGCCCGTCAAACCCAAGGATGCAGATCAGGAACACATCAGTGTCCTCATCCAGAACCTACTCGCCGAAGATGAAGTCATGTGCGAGGATGTGGCAGACGAACCAGAGCCCATCTCCGAAGAAGACGAATTCAAGGCTGTTGTCATTCCAGAGGAGCCGCCAACCAAAAAGAAAATGGTGCTGCTAAACAAGAGAGCCGTACGGCAGCCTAGCATAGATGAAGATGTCTACATTTATGAGCATGAGGAAATTTTGGCACCAAAGAAGGAAAAGGTCGAAGCCAAGTCAACAGTTAAGCTAACAGTTCAAGCGGAGGACAGCCAGAGTGAGGGAGAAGCCGAAGAGAGTCATGTGGTTCTCTTCGACTTTGTGATGATCAAAGAAAAGGATGACATTGACAACATTGCCGAGTACTTGTCCAAGGTGGTAAAGACCAGCTTCGAGAACCTTACCTTTGAATGGTCCATGGAGTGCAAACACTGCTCCCAGAAGTGCTCCACCTTTGAGAGCCTTCTGAGTCACACGCTAAAAGCCCATGAATCCCGGGGTAATGCCTACAAGTGTCCCATTGATGGCTGCAACAAGAAGCTGAAGGGCAGCAAATTTCTGGCCATGCATTTGGTTGTTTTGCATGCTCCCGTAGCTGAAATACCAATTTACGGCAGCTGTCCCGAGTGCAAGATGACATTCTCCAACATATTGCAGTATAACAAACACTCTTGCGCTCATATGATAAAAAAGAAGCGCGGTGTTCGTCTATATTGTGAAATGTGTGCGCTGGAGTTTCCCTCCTGGAAGCGGTTCAACTTTCACAATCAATTCCATTTGGAGAAGCACAGGCCTCGCGCTTGCTTTGTCTGTGATTATGCCAGCACCAACATCGATGAGCTGTTCCAGCACTTAAATTACTCCCATGAGCCTGTGGGCACCTTGTTTTGCGACCTTTGCGATCGGACTTTCCGGGATCCTGCGGTGTTCATGGAGCACAATAAGTCGCATGCCAATGTTAGCAGCACTACTTATCACTGCAGCGAATGCATGGCGCCTTTTGATTCACGAGGTCGCCTAAATGGACACATGCGCTCCATGCATGGCAGCATTATTAGCTGCGAGCTCTGTTCCCGGGAGTTTGGCAGCGAGGCCACCTACAGCATACACATGAAGAAGCATCTGATTATCGAGCGGGATCTGCACATTTGCCCCAACTGTGGACTGCTGGACGATAGCCAGGAGAAGATGGCTGCACATGCCGGAGCCAAGAATTCGCCCTGCTTTGGCGCGAAAATATATACGGAGATGACGCGCGATGCCTTTGCCTGTGAATACTGTTCGTCGTACTTTAAGCAAAAGACCGACCTGCAAGCACATCGCGAATCGGGAATCCATAAGAATGGTTTGTTTTGGTGCCAGCCGTGCGGCAAGGATTTTCCACACATGAAACTGTACCGTCATCACCTGCGCAACTATCAGAAACTGCGAACAGATACGACGCATCGTAAGCTCGAGATCTGTATCTTCTACATGTGTGATCAGAAGGACTGCAAGGAGGCCTATGTTAACTGGAACTCGCTGTATACGCACAAGCGACGCACCCACGAATCGTCGGATAAGCAGGCGGCGACGGCTTCAAAGTCCGGCCAAGATTGGGTTTGCCAGTTCTGTTTGAAGGAGTGTCGCTCGAAGATGTCCTTGTCTGTTCATGTGGCAAGGAGCCACAATAATGACAACGTGGTCTGTTCCTTATGCAATTCCTCGTACAAAAGCCAGGATGCCTTGGACAAGCATCATGCCTACTGGCATGAGCCCATCGAGTGTCCGCAGTGCTTCAAAATTGTCAAAAATCGTCGAAATTACGACACGCATGTTAATGTGGTGCATTCAAACAAAAAACGCTATGCCTGCGGTGTTTGTGAGAAAGGATTCTATCACAAAAGCGAAATGGAGGCTCATCAAAGGCTCCATGGCCAATTGTACAGCTGCGAACAGTGCAGCTTCACCACACGAAACAAGAAGTCTCTGTCCGTTCATGTCCTCGGTCAGCACTACAAGCGTTTCGCCTTCGAGTGCAAGATTTGCAACAAGAGATTCGGACGTCGTCAGGGCCTGAATACGCACATACAGCGGCAACATGGTTCCAAGTACTTGTGTCGGTATTACTTTGAGGGTGGCTGCGGGCGCACCTTTGTCAGTCGTTCTCAACTTAATGTTCATGTAAGGAAAGTGCACGAGGGAAGTATTTGTCTGCAGGAGGAGGAGGAGATGGAGGAAGAGGTTGACAGCGATGGGCCATCCACATCCAAGAGGCGCTGCTATCGCATTGACGATGATAGCAATATTGAGTTTGTGGGAATTGGAGAGAGCGATGAGCTGGATGACGATGAGGAGGAGATTGAGGAGGATGAGGAATTTGTGGACGATCCCGAATCAGACACTAAGCATTAA
- Protein Sequence
- MSENQKNNSCLHCSVFNTKYRYQEIFDEFGAELGLQSLLAKHFQLNVEPDPQQRQLLCEVCVNTLIRLFDIDELQRQRDAARGGRIKHSSPQPHQQTVVNPVAVKVPPAVAKPAPPATDAPKRAKILKPVVVAPPPVPSIREPSARICKRVAPPPVLPAASKPSGKVNECAKPAKEPVKPAKEASPVKPKDADQEHISVLIQNLLAEDEVMCEDVADEPEPISEEDEFKAVVIPEEPPTKKKMVLLNKRAVRQPSIDEDVYIYEHEEILAPKKEKVEAKSTVKLTVQAEDSQSEGEAEESHVVLFDFVMIKEKDDIDNIAEYLSKVVKTSFENLTFEWSMECKHCSQKCSTFESLLSHTLKAHESRGNAYKCPIDGCNKKLKGSKFLAMHLVVLHAPVAEIPIYGSCPECKMTFSNILQYNKHSCAHMIKKKRGVRLYCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCDYASTNIDELFQHLNYSHEPVGTLFCDLCDRTFRDPAVFMEHNKSHANVSSTTYHCSECMAPFDSRGRLNGHMRSMHGSIISCELCSREFGSEATYSIHMKKHLIIERDLHICPNCGLLDDSQEKMAAHAGAKNSPCFGAKIYTEMTRDAFACEYCSSYFKQKTDLQAHRESGIHKNGLFWCQPCGKDFPHMKLYRHHLRNYQKLRTDTTHRKLEICIFYMCDQKDCKEAYVNWNSLYTHKRRTHESSDKQAATASKSGQDWVCQFCLKECRSKMSLSVHVARSHNNDNVVCSLCNSSYKSQDALDKHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYACGVCEKGFYHKSEMEAHQRLHGQLYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKICNKRFGRRQGLNTHIQRQHGSKYLCRYYFEGGCGRTFVSRSQLNVHVRKVHEGSICLQEEEEMEEEVDSDGPSTSKRRCYRIDDDSNIEFVGIGESDELDDDEEEIEEDEEFVDDPESDTKH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00609312;
- 90% Identity
- iTF_00526052;
- 80% Identity
- -