Basic Information

Insect: Drosophila kanapiae
Gene Symbol: -
Assembly: GCA_008042475.1
Location: VNJM01003527.1:155392-159231[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.46 36 5.1 6.6 2 23 353 375 352 375 0.96

2 17 0.049 3.9 8.2 0.1 1 23 382 407 382 407 0.94

3 17 0.032 2.5 8.8 2.2 2 23 418 439 418 439 0.93

4 17 0.041 3.3 8.4 0.1 3 23 480 501 479 501 0.95

5 17 0.0039 0.31 11.6 0.4 3 23 509 529 507 529 0.95

6 17 0.029 2.3 8.9 0.7 1 23 537 560 537 560 0.97

7 17 0.0057 0.46 11.1 0.3 2 23 565 586 564 586 0.97

8 17 0.0022 0.17 12.4 0.5 1 22 634 655 634 658 0.90

9 17 0.33 26 5.6 1.4 3 21 665 683 665 684 0.90

10 17 0.098 7.8 7.2 0.6 1 23 703 728 703 728 0.96

11 17 0.78 63 4.4 1.4 2 23 746 768 745 768 0.94

12 17 0.0057 0.45 11.1 0.3 2 23 774 796 773 796 0.92

13 17 0.017 1.3 9.6 0.2 2 23 800 822 799 822 0.95

14 17 2e-05 0.0016 18.8 1.0 1 23 828 850 828 850 0.97

15 17 0.0081 0.65 10.6 0.9 1 23 854 877 854 877 0.93

16 17 1.4e-05 0.0011 19.3 1.4 1 23 883 906 883 906 0.97

17 17 0.00017 0.014 15.9 0.4 5 23 919 938 910 938 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.46	36	5.1	6.6	2	23	353	375	352	375	0.96
2	17	0.049	3.9	8.2	0.1	1	23	382	407	382	407	0.94
3	17	0.032	2.5	8.8	2.2	2	23	418	439	418	439	0.93
4	17	0.041	3.3	8.4	0.1	3	23	480	501	479	501	0.95
5	17	0.0039	0.31	11.6	0.4	3	23	509	529	507	529	0.95
6	17	0.029	2.3	8.9	0.7	1	23	537	560	537	560	0.97
7	17	0.0057	0.46	11.1	0.3	2	23	565	586	564	586	0.97
8	17	0.0022	0.17	12.4	0.5	1	22	634	655	634	658	0.90
9	17	0.33	26	5.6	1.4	3	21	665	683	665	684	0.90
10	17	0.098	7.8	7.2	0.6	1	23	703	728	703	728	0.96
11	17	0.78	63	4.4	1.4	2	23	746	768	745	768	0.94
12	17	0.0057	0.45	11.1	0.3	2	23	774	796	773	796	0.92
13	17	0.017	1.3	9.6	0.2	2	23	800	822	799	822	0.95
14	17	2e-05	0.0016	18.8	1.0	1	23	828	850	828	850	0.97
15	17	0.0081	0.65	10.6	0.9	1	23	854	877	854	877	0.93
16	17	1.4e-05	0.0011	19.3	1.4	1	23	883	906	883	906	0.97
17	17	0.00017	0.014	15.9	0.4	5	23	919	938	910	938	0.90

Sequence Information

Coding Sequence: ATGTCGGAAAACCAGAAAAACAATAGCTGCCTGCATTGTAGTGTTTTCAATACGAAATACCGGTACCAGGAGATCTTCGATGAGTTCGGCGCGGAGCTCGGCCTGCAATCGTTGCTGGCCAAGCACTTTCAACTGAATGTGGAACCCGATCCACGGCAGCGTCAGCTTCTGTGCGAGGTTTGCGTCAACACACTCATCCGGCTGTTCGATATCGATGaactgcaacggcaacagAATGCGGCGAGGTCCAGAAACAAACACCCCGGCCCGGAGCCGCCCCAACAAACTGTTGTCAATCCCGTTGCAGTCAAGGCTCCGCCAACGGCAGCCAAGCCTGCTCCTCcccctcctgctgctgatgctccCAAAAGGGCAAAGATTCTCAAATCCTTAGTGGTGGctgcacctcctcctcctcccatcAGGGAACCAAGTGCACGGATTTGCAAGAGAGTTGCGCCACCTCAGGTTGCATCTAAGCCATCTGGTAAAGTCTATGAGCCTGTAAAGCCTGCCAAGGAGCCTGCGAAGCCTGCCAAGGAGCCTGTAAAACCTGCCAAGGAGCCTGTGAAGCCTGCCAAGGAGGCATCGCCCGTCAAACTCAAGGATGCAGATCAGGAACATATCAGTGTCCTTATACAAAACCTACTCGACGAAGATGAAGTCATGTGCGAGGATGTGGCAGACGAACCAGAGCCCATCTCTGAAGAAGTAGAATTCAAGGCTGTTCCCATTCCAGAGCAGCCGgcaatcaaaaagaaaatggtgCTGCTAAACAAGAGAGCCGTGCGGCAGCCTAGTATAGATGAAGATGTTTACATTTACGAGCATGAGGaaattTTGGAACCAAAGAAGGTGAAGGCCGAAGCCAAGTCATCAGTTAAGCTAACAGTTCAAGCGGAGGACAGCCAGAGTGAGGGAGAAGCCGAAGAGAGTCATGTGGTTCTCTTCGACTTTGTGATGATTAAAGAAAAGGATGACATTGACGACATAGCCGAGTATTTATCTACGGTGGTGAAGACCAGCTTTGAGAAGCTAACCTTTGAATGGGCCACGAAGTGCAAACACTGCTCCTTGAAGTGTTCCAACTTTGAGAGCCTTCTAAGTCACACGCTAAAGTCTCATGAATGCCGCGGTAATGCCTACAAGTGCCCAATTGAAGGCTGCAACAAGAAGCTGAAGGGCAGCAAATTTCTGGCCATGCATTTGGTTGTTTTGCATGCTCCCGTAGCTGAAATACCAATTTACGGCAGCTGTCCGGAGTGCAAGATGACCTTCTCCAACATCTTGCAGTATAACAAACACTCTTGCGCTCATATGATCAAAAAGAAGCGCGGTGTTCGTTTATATTGTGAAATGTGTGCGCTGGACTTTCCCTCCTGGAAGCGTTTCAACTTTCACAATCAATTCCATTTGGAGAAGCACAGGCCTCGCGCTTGCTTTGTCTGTGATTATGCCAGCACCAACATCGATGAGCTGTTCCAGCATTTAAATTACTCCCATGAGCCGGTGGGCACCTTGTTTTGCGACCTTTGCGATCGCACTTTTCGTGATCCTGGGGTGTTCATGGAGCACAATAAGTCGCATGCCAATGTCAGCAGCACTACGTATCACTGCAACGAATGCATGGCGCCTTTCGATTCACGTGGTCGCCTAAATGGACACATGcGCTCCATGCACGGCAGCATTATTAGCTGCGAGCTCTGTTCCCGGGAGTTTGGCAGCGAGGCCACCTACAGCATACACATGAAAAAGCATCTGATTATCGAGCGCGTTCTGCACATTTGCCCCAACTGTGGACTGCTGGACGATAGCCAGGAAAAGATGGCTGCACATGCCGGTACCAAGAATTCGCCCTGCTTTGGCGCCAAGATATACACGGAGTTGATGCGCGATGCCTTTGCCTGTGAATACTGTTCGTCGTACTTTAAGCAAAAGACCGACCTGCAAGCACATCGCGAGTCGGGCATCCATAAAAATGGTTTGTTTTGGTGCCAGCCGTGCGGCAAGGATTTTCCTCACATGAAACTGTACCGCCATCACCTGCGCAACTATCAGAAACTGCGAACGGATACGACGCATCGCAAGCTGGAGATCTGTATCTTCTACATGTGCGATCAAAAGGACTGCATGGAGGCCTATGTGAACTGGAACTCTTTGTATACGCACAAGCGGCGCACCCACGAATCGTCGGATAAGCAGGCGGCGACGGCTTCAAAGTCCGGTCAGGATTGGGTTTGCCAGTTCTGCATGAAGGAGTGTCGCTCGAAGATGTCCTTGTCTGTTCATGTGGCAAGGAGTCACAATAATGATAACGTGGTCTGTTCCTTATGTAATGCCTCGTACAAGAGCCAGGATGCCTTGGACAAGCACCATGCCTACTGGCATGAGCCCATCGAGTGTCCGCAGTGCTTTAAAATTGTCAAGAATCGTCGAAATTACGACACGCATGTCAATGTGGTgcattcaaacaaaaaacgctATGCCTGCAGTGTTTGTGAGAAAGGATTTTATCACAAAAGCGAAATGGAGGCTCATCAAAGGctccatggCCAGTTGTACAGCTGCGAACAGTGCAGCTTCACCACGCGAAACAAGAAGTCTCTGTCCGTTCATGTCCTGGGTCAGCACTACAAGCGTTTCGCCTTCGAATGCAAGGTTTGCAACAAGAGATTCGGACGTCGTCAGGGCCTGAATACGCACATACAGCGGCAACATGGTACCAAGTACTTGTGTCGCTATTACTTTGAGGGTGGCTGCAATCGCACCTTTGTCAGTCGTTCTCAGCTGAATGTTCATGTACGGAAAGTGCACGAGGGAAGTATTTTTctgcaggaggaggacgaggttGACAGCGATGGGCCATCTACATCCAAGAGGCGCTGCTATCGCATTGACGATGACAGCAATATTGAGTTTGTGGAAATTGGAGAGGGCGAAGAGCTGGACGACGATGGTGAAGAGGAGGAGGTtgaggaggaagaggaattTGTAGACGATCCCGATTTAGACACTAAGCATTAA
Protein Sequence: MSENQKNNSCLHCSVFNTKYRYQEIFDEFGAELGLQSLLAKHFQLNVEPDPRQRQLLCEVCVNTLIRLFDIDELQRQQNAARSRNKHPGPEPPQQTVVNPVAVKAPPTAAKPAPPPPAADAPKRAKILKSLVVAAPPPPPIREPSARICKRVAPPQVASKPSGKVYEPVKPAKEPAKPAKEPVKPAKEPVKPAKEASPVKLKDADQEHISVLIQNLLDEDEVMCEDVADEPEPISEEVEFKAVPIPEQPAIKKKMVLLNKRAVRQPSIDEDVYIYEHEEILEPKKVKAEAKSSVKLTVQAEDSQSEGEAEESHVVLFDFVMIKEKDDIDDIAEYLSTVVKTSFEKLTFEWATKCKHCSLKCSNFESLLSHTLKSHECRGNAYKCPIEGCNKKLKGSKFLAMHLVVLHAPVAEIPIYGSCPECKMTFSNILQYNKHSCAHMIKKKRGVRLYCEMCALDFPSWKRFNFHNQFHLEKHRPRACFVCDYASTNIDELFQHLNYSHEPVGTLFCDLCDRTFRDPGVFMEHNKSHANVSSTTYHCNECMAPFDSRGRLNGHMRSMHGSIISCELCSREFGSEATYSIHMKKHLIIERVLHICPNCGLLDDSQEKMAAHAGTKNSPCFGAKIYTELMRDAFACEYCSSYFKQKTDLQAHRESGIHKNGLFWCQPCGKDFPHMKLYRHHLRNYQKLRTDTTHRKLEICIFYMCDQKDCMEAYVNWNSLYTHKRRTHESSDKQAATASKSGQDWVCQFCMKECRSKMSLSVHVARSHNNDNVVCSLCNASYKSQDALDKHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYACSVCEKGFYHKSEMEAHQRLHGQLYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKVCNKRFGRRQGLNTHIQRQHGTKYLCRYYFEGGCNRTFVSRSQLNVHVRKVHEGSIFLQEEDEVDSDGPSTSKRRCYRIDDDSNIEFVEIGEGEELDDDGEEEEVEEEEEFVDDPDLDTKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00609312;
90% Identity: iTF_00569851;
80% Identity: -