Basic Information

Insect: Drosophila parvula
Gene Symbol: zfh1
Assembly: GCA_018904695.1
Location: JAEIIG010037150.1:6473-10797[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.6e-05 0.002 18.5 1.0 1 23 151 173 151 173 0.97

2 15 0.00081 0.062 13.8 1.2 3 23 181 201 179 201 0.94

3 15 0.00027 0.02 15.3 0.2 1 23 371 393 371 393 0.98

4 15 0.00013 0.01 16.3 0.8 1 23 399 421 399 421 0.98

5 15 1.3e-05 0.00095 19.5 2.8 1 23 453 475 453 475 0.97

6 15 6.7e-06 0.00051 20.4 1.6 1 23 510 532 510 532 0.95

7 15 0.011 0.8 10.3 1.3 1 23 538 561 538 561 0.97

8 15 0.026 2 9.1 0.4 3 19 570 586 569 587 0.95

9 15 0.00015 0.012 16.1 5.6 1 23 596 618 596 618 0.97

10 15 0.046 3.5 8.3 0.4 2 23 624 645 623 645 0.96

11 15 9e-06 0.00068 20.0 1.0 1 23 654 676 654 676 0.98

12 15 0.001 0.077 13.5 0.1 3 23 684 704 682 704 0.97

13 15 5.5e-05 0.0041 17.5 0.5 1 23 710 732 710 733 0.95

14 15 0.036 2.7 8.6 0.3 1 23 743 765 743 765 0.97

15 15 0.0055 0.42 11.2 0.2 1 23 1314 1336 1314 1336 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.6e-05	0.002	18.5	1.0	1	23	151	173	151	173	0.97
2	15	0.00081	0.062	13.8	1.2	3	23	181	201	179	201	0.94
3	15	0.00027	0.02	15.3	0.2	1	23	371	393	371	393	0.98
4	15	0.00013	0.01	16.3	0.8	1	23	399	421	399	421	0.98
5	15	1.3e-05	0.00095	19.5	2.8	1	23	453	475	453	475	0.97
6	15	6.7e-06	0.00051	20.4	1.6	1	23	510	532	510	532	0.95
7	15	0.011	0.8	10.3	1.3	1	23	538	561	538	561	0.97
8	15	0.026	2	9.1	0.4	3	19	570	586	569	587	0.95
9	15	0.00015	0.012	16.1	5.6	1	23	596	618	596	618	0.97
10	15	0.046	3.5	8.3	0.4	2	23	624	645	623	645	0.96
11	15	9e-06	0.00068	20.0	1.0	1	23	654	676	654	676	0.98
12	15	0.001	0.077	13.5	0.1	3	23	684	704	682	704	0.97
13	15	5.5e-05	0.0041	17.5	0.5	1	23	710	732	710	733	0.95
14	15	0.036	2.7	8.6	0.3	1	23	743	765	743	765	0.97
15	15	0.0055	0.42	11.2	0.2	1	23	1314	1336	1314	1336	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGGCTATGGCGGCATCCAGTGGATACAGCACCACCCCGCCGCAGGCGACTCCTCTGAGACGGACATTCTGGAGCACGAAGAAGCCGACGGCGATGATATGGTGAGCGGAGGGGAAGCCGACCCCGATGAGGACGCGGATGCTGATCTGGACCATATGGCGGCCGAGAACCTAATCTTTATGGCGCGCGAGGGGCAGCTGGGCGAGATAATAGCCGCCAACGAGGGTGCTGTCCTGGTCACCGCCGATGGCACTACGGTGGCCTATGCGGAATCCTTTGACGACGACGCCCAGGTGGTCACCGAGGAGGTAATCACCGATGACTGGGTGCAGCACCAAGGAGCCGAGCGTGTGGAAATAGCAGCAGAGCAGATAGCTGGCATCAGCAGCTCTCAGGAACTATTGGACATGGAACAGGACGAGTACACGGCCCTGCGACCCTATCCCTGCGACTTTTGCAGCCGACGCTTCCGGAAGAAGGCCAGCTTGAACAACCATATGCTGGCCCATCAGAATGACAGACCTCACCTGTGCAAGCTGTGCGGCGCCCGCTTCTCCCGCCGGGCGGAGCTCATCAGCCACTTTAAGGCTCACGCCGAGGCCCAGGATGCTGCTGATGCCGAGGCAGCAGCAGCCGCAGCCGTTTCAGCTTCCTCTTCCATTAAATTCGAAAATCAGGGCCACAGGCAAATGGATGATCACTACTACGAGCAGGAGTGGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAGGTTCAGTTTGTGGCCAGCTACACAGCATCAGTGGCTCCTCCACCTGCCCCCTCGCGTGGTAGAATTAGTCGGCTGAAGCCAAAGGACGAGAGCAGCCAGTTCATTGTAATTTCCGACAAGCCGGTGTCCAGCGAACTGCGGGACTACATGGACAGTGAGCCGGCTGCTCAGACAGTGGTGGCCACAGCGCAGCCCATTGATCCTCCGCCTGCGCTGCAGCCAAAATTTCCGGTGCTGGACGACAGCAAGCCCTTTGTGTGTCAGCAGTGCGGATTGGCTTTTGCACGGGAAAAGGCGCTAGTCTCGCACACCAAGAACCATCGCGTGGATTCTCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCATCAATTTGAGGAGAGCAACTCGGAGTATGATCCCGCCTCTGGCGATGATAGCGCCACCGAAACATCGGAGCCGGAGGAGCAGCTGTACGGAGAGTTCTACTGCAAGGATTGCGGCATCTCCTTCCATCGCCAGGACTTGCTGCGACGTCATGCCAAGCAGCATTTGAAGCAGCACGATCATCCGGCGGCCGGGGGAGACGGCAGCTGCTCGGATATCACAGCTGGCGGGGATCAGGCGTTACAGGCCAAAGATGGCAACGGCGGCCACTCTTGTCATACGTGCGGCAAAACATTTACCAGTGCCTCGGAGTTGGTGTCCCATGCCGAAATCCATGCCAGGTTTCCGCCCTTCAAATGCGTCCTTTGCGGCATTAGTTTCTATGAGGAGCAGGCCATCAAGCGGCACTTGCACACCCGCCACCCCAACGAACTGAAGGCCAACTCCTGCGTGCTGTGTGGCAAGGAGTGTCGCGACCGCAAGGCCTTAATCAAGCACGCTTGGGATCACTCGCGCGAGAAGTGCCACTCGTGCTCAAAGTGCGGGAAGAACTTCCACAACAAGGCGCGTCTGAAGCGCCACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGCGAGGTGTGTCAGGAGGAGTTCCCAGACGGCAGGACCCTATCCAATCACCGGCACTCGCACAGTACCACTTCGCCGGGCAAACTCTTTCCCTGCCACGAATGCGGCAAGACATTTGGCTCACGCAGCTCCCAGCAGATTCATGTCCGCATCCATACGGGTGAGCGTCCCTATGGCTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGAACGTTGCGCAAGCACGAAAGGATTCACACGGGCGAGAAGCCATACGCCTGCTCGGTGTGTCCGCGTGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGCTCCCATCATTCGGGGCTGGATGTTTCGCGGAATACGTATCACTGCACCGTGTGCTCCGAGGATCTGGCCTCGTCCAACGACCTCATACAGCACCTCATACAGCACAGTGATTCAAACACCGCCAAGCAGCGCCAACCGGTTACGGGTCCCCGAAAGTACAAGCGTCGCCGCAAGCTGCAGCCCCACGAGATCGCGCACATGCGGGCAGAGAACAAGGATGGCAATGGAGACGATGAGGAGGAGGTTCTCGGCGGTGAAGGGGATGCAAATGGGGATGGCGATGAAGATGAGTACGCCAGCGATATCGATCTCTGCGACTTTGATGTGGAGAATGTGAACGATCTGTTTGAAATGGCCGGACCGACGCCAAAGAAGGAGAAGCGCACGCGGACAACGGCGGCCGCAACCAAGGCAGAACCACACAAGCCTGTTGCCAATGGCGGCGGATCGGCGACGGCGGTGAAGCCTGCCCAGGAGAAGAACAAGTCCAAGCTGCGATATGACTCCACCAGCAGCCAGCAATCGGACCGCATTTGGGAGGAGAAGTTCCTGCAGGACAGTCAGGGGGCGCTCTTTCAAATCGACTCCCTGGTGGTGGTCAACGATACTCACCTGCAGCCCGCGAGCTCAGCCATGCCCAAGACGAGAGGTGCCGCCCGGCAGCAGCAGGGAAAAGGAGCACAGCCGGCAGGCAGCTCCAATTCCTCGGTGGCCACTTCATCAGCCTCTGTGTCCACCTTCAATTCCTTAGCCAGTAGCCGCAACAGGAAGAAGACGGGAACCATAAAGACAACACCTGCCAGCAGTAGCAGCAGCAGCTCCTCGCGACCCCGCATGATACACACGGAGAAGGCCAAGGTGCCGACCAGGGGCTTACCCGGCGGAGAGTTGGCCAAGAAGACACGCTCCAAGACCTACATCACGCGCACGGAGACAAGCAATCTGAGCGGCTTGGACAAGTCGCGCAGCAGCCGAGCTTCCAACATTGTGGATGACTACGAAATCATTTCGCCAGCTACACATCCACCAAACCAGATCAGCTCCAGCCCGTTGCACATCAAGCAGGAGCAGGAGCAGCAGCATCACAACCACCACCGTGTCCAGATGATGTACGACGACAATCTGCTAATAGACGCTGCCCTGCTGCGGGAGAAGACCTACGAGAAGTTCAACCCGAGCATTGTGAACGATCTGGAGGAGATTCTGCGCTCGCCGCTCAAACACGAGCGGAATACCCGCCTGCGCTTCACCAGCGAATCCTCGAACACGCCCCAGTTTCTGCCCGAAGAAGAACAGAATCTGATCAAGATCGAGCCCACGTCGCCGGATTTGCGGGAGATGCTGGAGAGCCAAAGCCAAAGGGTGAGAGTGCTAAGCGGGAACACACCGTCGCCCTCATCTTCCTCCGCTGCCCGTACTTCGCGTCATCGTCAGATCACTACCAATGGACCCAGAGCAGGAAGCAAGAGATCCGCAGCAGGCGGAAGTAGTGGCAGCGCTAGTAAATCCTCACCTGTCACCGGAGTGGCAGCCAAGAAAGTGAGCACTGCTGCCAGCAAGGTGAGCAGCTCGTCCTCGTACCTCAATTACGGTGTGGATGCCTACAATGTGAACGTACCTGCCAGTGCCAACACTGCCGATGTGGGCAGCGGTTTCTTCTCCATCTCGGAGGTCGTATCGGCCGCCGATGCCGCTGATGCGGCGGCAAAGGCGGCGGCGGCCGGGACACCGGAGCGGAAAACACGCAGTTTCGAGTGTGAAATGTGCTCGGCCATCTTTTATGATCGAGCCCAATTATTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQGYGGIQWIQHHPAAGDSSETDILEHEEADGDDMVSGGEADPDEDADADLDHMAAENLIFMAREGQLGEIIAANEGAVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAVSASSSIKFENQGHRQMDDHYYEQEWXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEVQFVASYTASVAPPPAPSRGRISRLKPKDESSQFIVISDKPVSSELRDYMDSEPAAQTVVATAQPIDPPPALQPKFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSATETSEPEEQLYGEFYCKDCGISFHRQDLLRRHAKQHLKQHDHPAAGGDGSCSDITAGGDQALQAKDGNGGHSCHTCGKTFTSASELVSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVSRNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAENKDGNGDDEEEVLGGEGDANGDGDEDEYASDIDLCDFDVENVNDLFEMAGPTPKKEKRTRTTAAATKAEPHKPVANGGGSATAVKPAQEKNKSKLRYDSTSSQQSDRIWEEKFLQDSQGALFQIDSLVVVNDTHLQPASSAMPKTRGAARQQQGKGAQPAGSSNSSVATSSASVSTFNSLASSRNRKKTGTIKTTPASSSSSSSSRPRMIHTEKAKVPTRGLPGGELAKKTRSKTYITRTETSNLSGLDKSRSSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHHNHHRVQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSNTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVLSGNTPSPSSSSAARTSRHRQITTNGPRAGSKRSAAGGSSGSASKSSPVTGVAAKKVSTAASKVSSSSSYLNYGVDAYNVNVPASANTADVGSGFFSISEVVSAADAADAAAKAAAAGTPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00526001;
80% Identity: -