Basic Information

Insect: Drosophila kanapiae
Gene Symbol: zfh1
Assembly: GCA_008042475.1
Location: VNJM01000801.1:202228-206566[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.6e-05 0.002 18.5 1.0 1 23 148 170 148 170 0.97

2 15 0.00079 0.063 13.8 1.2 3 23 178 198 176 198 0.94

3 15 0.00026 0.021 15.3 0.2 1 23 372 394 372 394 0.98

4 15 0.00013 0.01 16.3 0.8 1 23 400 422 400 422 0.98

5 15 1.2e-05 0.00097 19.5 2.8 1 23 458 480 458 480 0.97

6 15 6.1e-05 0.0049 17.3 1.3 1 23 515 537 515 537 0.95

7 15 0.01 0.82 10.3 1.3 1 23 543 566 543 566 0.97

8 15 0.025 2 9.1 0.4 3 19 575 591 574 592 0.95

9 15 0.00015 0.012 16.1 5.6 1 23 601 623 601 623 0.97

10 15 0.044 3.5 8.3 0.4 2 23 629 650 628 650 0.96

11 15 8.8e-06 0.0007 20.0 0.3 1 23 659 681 659 681 0.98

12 15 0.0044 0.35 11.5 0.2 3 23 689 709 687 709 0.97

13 15 5.3e-05 0.0042 17.5 0.5 1 23 715 737 715 738 0.95

14 15 0.035 2.8 8.6 0.3 1 23 748 770 748 770 0.97

15 15 0.0054 0.43 11.2 0.2 1 23 1318 1340 1318 1340 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.6e-05	0.002	18.5	1.0	1	23	148	170	148	170	0.97
2	15	0.00079	0.063	13.8	1.2	3	23	178	198	176	198	0.94
3	15	0.00026	0.021	15.3	0.2	1	23	372	394	372	394	0.98
4	15	0.00013	0.01	16.3	0.8	1	23	400	422	400	422	0.98
5	15	1.2e-05	0.00097	19.5	2.8	1	23	458	480	458	480	0.97
6	15	6.1e-05	0.0049	17.3	1.3	1	23	515	537	515	537	0.95
7	15	0.01	0.82	10.3	1.3	1	23	543	566	543	566	0.97
8	15	0.025	2	9.1	0.4	3	19	575	591	574	592	0.95
9	15	0.00015	0.012	16.1	5.6	1	23	601	623	601	623	0.97
10	15	0.044	3.5	8.3	0.4	2	23	629	650	628	650	0.96
11	15	8.8e-06	0.0007	20.0	0.3	1	23	659	681	659	681	0.98
12	15	0.0044	0.35	11.5	0.2	3	23	689	709	687	709	0.97
13	15	5.3e-05	0.0042	17.5	0.5	1	23	715	737	715	738	0.95
14	15	0.035	2.8	8.6	0.3	1	23	748	770	748	770	0.97
15	15	0.0054	0.43	11.2	0.2	1	23	1318	1340	1318	1340	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGGCTATGGCGGCATGCAGTGGATACAGCACCACCCCGCCGCAGGTGATTCCTCCGAGACGGACATTCTGGAGCACGAAGACGCCGACGGCGATGATATGGTGAGCGGTGGGGATGACGAGGACGCGGATGCTGACCTGGACCATATGGCGGCCGAGAACCTCATCTTTATGGCGCGCGAGGGGCAGCTGGGCGAGATAATCGCGGCCAACGAGGGTGCTGTCCTGGTCACCGCCGATGGCACTACGGTGGCCTATGAGGAATCCTTTGACGACGACGCCCAGGTGGTCACCGAGGAGGTAATCACCGATGACTGGGTGCAGCACCAAGGAGCCGAGCGtgtGGAAATAGCCGCGGAGCAGATAGCTGGCATCAGCAGCTCTCAGGAACTATTGGACATGGAGCAGGATGAGTACACGGCCCTGCGACCCTATCCCTGTGACTTTTGCAGCCGACGCTTCCGGAAGAAGGCCAGTTTGAACAACCATATGCTGGCCCATCAGAATGACAGGCCTCACCTGTGCAAGCTGTGCGGCGCCCGCTTCTCCCGCCGGGCGGAGCTCATTAGCCACTTTAAGGCCCACGCCGAGGCCCAGGATGCTGCGGATgccgaggcagcagcagccgccgcagccgtTTCGGCTTCCTCTTCCATTAAATTCGAAAATCAGGGCCACAGGCAAGTGGATGATCACTACTACGAGCAGGAGTGGTCGCcttatcagcagcagcagcagcagcagcaggaacaggaacacgAACAGGAGCTAGTGCATCATGATCAGATGCTGCaacatcagcaggagcagcagcaacagcatcagcaactGGTCTGCAACAGCGAGGTTCAGTTTGTGGCCAGCTACACAGCATCAGTGGCTCCTCCACCTGCCCCCTCGCGTGGTAGGATTAGCCGCCTGAAGCCAAAGGACGAGAGCAGTCAGTTATTTGTAATTTCCGACAAGCCGATGACCAGCGAACTGCGGGACTACATGGACAGTGAGCCGGCGGCTCAGACGGTGGCAGCCACAGCGCAGCCCATGGCCATTGATCCTCCGCCTGAGCTGCAGCCAAAATTTCCGGTGCTGGACGACAGCAAGCCCTTTGTGTGTCAGCAATGCGGATTGGCTTTTGCACGGGAAAAGGCGCTAGTCTCGCACACCAAGAACCATCGCGTGGATTCTCCCTTCGAGTGCAACCAGTGCCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGATCACCAAAAAACCCATCAGTTCGAGGAGAGCAACTCGGAGTATGATCCCGCCTCTGGCGATGACAGCGCCAGCGAAACGTCAGAGCCGGAGGAGCTGCACGGGGAGGAGCTGTACGGGGAGTTCTACTGCAAGGATTGCGGCATCTCCTTCCATCGCCAGGACTTGCTGCGACGTCATGCCAAGCAGCATTTAAAGCAGCACGATCATCCGGCGACCGGGGGAGACGGCAGCTGCTCGGATATCACTGCTGCCGGGGATCAGGCGTTACAGGCCAAGGATGGCAACGGCGGCCACTCGTGTCATACGTGCGGCAAAACATTTCCCAGTGCCTCCGAGATGATGTCTCATGCCGAAATTCATGCCAGGTTTCCGCCCTTCAAATGCGTCCTTTGCGGCATTAGTTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGCACACCCGCCACCCCAACGAACTGAAGGCAAACTCCTGCGTGCTGTGTGGCAAAGAGTGTCGCGATCGCAAGGCCTTAATCAAGCACGCTTGGGATCACTCTCGGGAGAAGTGCCACTCGTGTTCCAAGTGCGGGAAGAACTTCCACAACAAGGCGCGTCTGAAGCGGCACATGGCCTCGCATCGGGACAAGTCGGTGGTGTGCGAGGTGTGTCAGGAGGAGTTCCCAGACGGCAGGACCCTATCCAATCACCGGCATTCGCACAGTACCACTTCGCCGGGCAAACTCTTTCCCTGCAACGAATGCGGCAAGACATTCGGCTCACGCAGCTCCCAGCAGATCCATGTCCGCATCCATACGGGTGAGCGTCCCTACGGCTGTCGCTTCTGCTGGAAGGCCTTCGCCGATGGCGGAACGTTGCGCAAGCACGAAAGGATTCACACGGGCGAGAAGCCATACGCCTGCTCGGTGTGTCCGCGTGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGCTCCCATCACTCGGGGCTGGATGTTTCGCGGAATACGTACCACTGCACCGTGTGCTCCGAGGATCTGGCCTCGTCCAACGACCTCATACAGCACCTCATCCAGCACAGTGATTCAAACACCGCCAAGCAGCGTCAACCGGTTACGGGTCCGCGAAAGTACAAGCGTCGTCGCAAGCTGCAGCCCCACGAGATCGCACACATGCGGGCAGAGCACAAGGAtggcgacgaggaggaggttCTCGGCGGCGAAGGCGATgcaaatggagatggagaggGCGATGAAGATGAGTACGCTAGCGATATCGACCTCTGCGACTTTGATGTGGAGAATGTGAACGATCTGTTCGAAATGGCCGAGCCGTCGCCCAAGAAGGAGAAGCGCAAGCGGACAACGGCGGCAGCCACCAAGGCAGAACCACACAAGCCTGTTGCCAATGGCGGCGGATCGGCGGCGTCGGTGAAGCCTGTCCAGGAGAAGAACAAGTCCAAGCTGCGATATGACTCCACCAGTAGCCAGCAATCGGATCGCATTTGGGAGGAGAAGTTCCTGCAGGACAGTCAGGGAGCGCTCTTCCAAATCGATTCCCTGGTGGTGGTCAACGATACTCACCTGCAGCCCGCGAGCTCAGCCATGCCCAAGACGAGAGGTGTcgcccggcagcagcagcagggaaaaGCAGCGCAGCCGGCAGGCAACTCCAATTCCTCGGTGACCACTTCATCAGCCTCTGTCTCCACCTTTACTTCCTCAGCCAGTAGTCGCAGCAGGAAGAAGACGGGAACTATAAAGACAACATCTCCcagcagtaacagcagcagctcctcgcgACCCCGCATGATACACACGGAGAAGGCCAAGGTGGCGACCAGGGGCTTACCCGGCGGAGAGTTGGCCAAGAAAACACGCTCCAAGACCTACATCTCGCGCACGGAGACAAGCAATCTGAGCGGCTTGGACAAGTCGCGCAGCAGCCGAGCCTCCAACATTGTGGATGACTACGAAATCATTTCGCCAGCTACACAGCCACCAAACCAGATCAGCTCCAGTCCGTTGCACATCAAGCAGGAGCacgaacagcaacagcaccaccaCCGTTCCCAGATGATGTACGACGACAATCTGCTAATAGACGCTGCCCTGCTGCGTGAGAAGACCTACGAGAAATTCAACCCCAGCATTGTGAACGATCTGGAGGAGATCCTGCGCTCGCCGCTCAAGCACGAGCGGAATACCCGCCTGCGCTTCACCAGCGAATCCTCGAACACGCCCCAGTTTCTGCCCGAAGAAGAGCAGAATCTGATCAAGATCGAGCCCACGTCGCCGGATTTGCGGGAGATGCTGgagagccaaagccaaagggTGAGAGTGCTAGGCGGGAACACACCGTCGCCCTCGTCTTCCTCCGCTGCCCGGACTTCGCGTCATCGTCAGATCACTGCCAATGGACCCAGAGCAGGGAGCAAGAGATCCACAGGAAGCGGAAGTAGTGGCAGCCCTAATAAATCCTCACCTGGCCCCGGAGTGGCAGCCAAGAAAGTGAGCACTGCGGCCAGCAAGGTGAGCAGCTCGTCCTCGTACCTCAATTACGGTGTGGATGCCTACAATGTGAACGTACCTGCCAGTGCCAGCACTGCCGATGTGGGCAGCGGTTTCTTCTCCATCTCAGAGGTCGTGTCGGCTGCCGATGCCGCTGATGCGGCGgcaaaggcggcggcggccgggAAGCCGGAGCGGAAAACACGCAGTTTCGAGTGTGAAATGTGCTCGGCCATCTTTTATGATCGAGCTCAATTATTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQGYGGMQWIQHHPAAGDSSETDILEHEDADGDDMVSGGDDEDADADLDHMAAENLIFMAREGQLGEIIAANEGAVLVTADGTTVAYEESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAAVSASSSIKFENQGHRQVDDHYYEQEWSPYQQQQQQQQEQEHEQELVHHDQMLQHQQEQQQQHQQLVCNSEVQFVASYTASVAPPPAPSRGRISRLKPKDESSQLFVISDKPMTSELRDYMDSEPAAQTVAATAQPMAIDPPPELQPKFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGDDSASETSEPEELHGEELYGEFYCKDCGISFHRQDLLRRHAKQHLKQHDHPATGGDGSCSDITAAGDQALQAKDGNGGHSCHTCGKTFPSASEMMSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCNECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVSRNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDGDEEEVLGGEGDANGDGEGDEDEYASDIDLCDFDVENVNDLFEMAEPSPKKEKRKRTTAAATKAEPHKPVANGGGSAASVKPVQEKNKSKLRYDSTSSQQSDRIWEEKFLQDSQGALFQIDSLVVVNDTHLQPASSAMPKTRGVARQQQQGKAAQPAGNSNSSVTTSSASVSTFTSSASSRSRKKTGTIKTTSPSSNSSSSSRPRMIHTEKAKVATRGLPGGELAKKTRSKTYISRTETSNLSGLDKSRSSRASNIVDDYEIISPATQPPNQISSSPLHIKQEHEQQQHHHRSQMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSNTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVLGGNTPSPSSSSAARTSRHRQITANGPRAGSKRSTGSGSSGSPNKSSPGPGVAAKKVSTAASKVSSSSSYLNYGVDAYNVNVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00569815;
80% Identity: -