Dpav004810.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila parvula
Gene Symbol
ZNF296
Assembly
GCA_018904695.1
Location
JAEIIG010013546.1:68922-73409[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0018 0.13 12.8 1.5 1 23 210 232 210 232 0.96
2 25 2.3 1.8e+02 2.9 3.3 1 16 239 254 239 261 0.79
3 25 1.4 1.1e+02 3.6 0.6 2 23 293 314 292 314 0.93
4 25 0.0024 0.18 12.4 0.4 1 23 387 410 387 410 0.94
5 25 7.3 5.5e+02 1.4 2.7 1 23 451 473 451 473 0.91
6 25 0.0035 0.26 11.8 0.1 3 23 484 504 482 504 0.95
7 25 0.042 3.2 8.4 0.4 1 23 584 607 584 607 0.96
8 25 0.0099 0.75 10.4 0.3 2 22 614 634 613 634 0.93
9 25 0.048 3.6 8.2 1.8 2 23 644 665 644 666 0.95
10 25 0.0025 0.19 12.3 1.5 2 23 688 709 687 709 0.97
11 25 5.1e-06 0.00038 20.8 4.3 1 23 716 738 716 738 0.98
12 25 0.017 1.3 9.6 0.5 1 23 873 896 873 896 0.91
13 25 0.08 6.1 7.5 3.2 1 22 903 924 903 924 0.95
14 25 0.096 7.3 7.3 1.2 1 23 933 956 933 956 0.93
15 25 8.5e-05 0.0064 16.9 2.3 2 23 975 996 974 996 0.97
16 25 0.00012 0.0087 16.5 0.9 1 23 1003 1025 1003 1025 0.98
17 25 0.029 2.2 8.9 0.0 2 21 1052 1071 1051 1072 0.93
18 25 0.035 2.7 8.7 4.0 1 23 1118 1141 1118 1141 0.96
19 25 0.0028 0.21 12.1 0.5 1 23 1178 1201 1178 1201 0.96
20 25 0.0004 0.03 14.8 1.4 1 23 1227 1250 1227 1250 0.97
21 25 5.1e-06 0.00039 20.7 0.2 2 23 1277 1298 1276 1298 0.95
22 25 0.0026 0.2 12.2 2.6 1 23 1304 1326 1304 1326 0.99
23 25 2e-06 0.00015 22.0 2.0 1 23 1332 1354 1332 1354 0.97
24 25 1.8e-07 1.3e-05 25.3 2.4 1 23 1360 1382 1360 1382 0.99
25 25 0.014 1 10.0 0.1 1 21 1388 1408 1388 1412 0.89

Sequence Information

Coding Sequence
ATGCTTCCCTCAAATATCTGCCGCACTTGTGCGGTTCAGAACAAAGATTTGCGGCCCTTGTCTAGCTGTCTGGGCAAAGACGCCTCCAAAACATTCTATGATGTGCTCCAAGAGCTAACCCAGATCGATCCCCTGGAGGAGAGCTCGGATGACAATCTGCCGCAGCATCTATGCACCGACTGCTTGGCGAGTTTGGAAAGTGCCTACGCCTTTGTGGAACAGGCCCGGAAAGTCAATGGCGAGCTGTTGGTTCGCTTGCGGGAATGCCTTGACGAAATGCCCATTGACATACCGCAGGAGCAGCAGAAGATCATCAAAACCGAAGTGGATATAGACGAAGCGACTCCCAAGTGTGATGTGGATGTAGATAACGCAGAAATATCGCCTGTGGAGTTTAAATGGCAGCTGAAAAGTGACAGCGATGAGGACTCTGCTGGAGCAGGAGCCAGTGATGAGAATGAGGTGGAGAGGAAGCCTTATCCTCTTAGGCGTAGTGCGCGCAAAATCAAGCTACCCGTGGAGAGCGATAATGAGGACTCAACTTTAGCGGAGATCGTCCCCATTAAACGCCGTCGTGGCCGACCGCCTGGCTCGGCCAAGCGCCAGAGCATGACCCCCGATGGACGCCACGCCTGCAAGGTGTGCGGCAAAACCTTCTCCTGGTTTCGCGATATGCAGCGTCATGCCCGAATCCATTTCGAGAAATCCAACGCCTACGTTTGCGATACCTGCGGCAAAGGATTCCTGCGTAAGGACAAGTATTCCTTCCATTTGCGCTGTCACGAAAAGCGTGAGGCCAAGAGCAAGGCTCTCCAGCTGGCCAGCGAGTGGCGCTTCGCCGAGCGGCTGTACAATTCCGGCAGGCTAAAGAGGATCGAGTGCAAGCTGTGTGGTCTAAAGTGCCTGCGAATTCAGGAGCTCCGAATTCACTTGGTCAGCCATGGGAAGGTGGAGAGCTTGCTCCAGTTGACTGAGGATAGCGATGTGATCAGGGAGCACTATGCCGACCAGCCTTGCAACTTGGAGGGCGTGAGACAACAAATTATTAAGGACATAGCGGCTGGACAGCTGGATAAGTTCTGTTCCGTGGTAAATTTCCATGGCTATGAGCTGGGAGTGTGTGACTCGGACGAGGAAGCGACCAGCGCAGAGTCCAAATACGAGTGCACGGCGTGCAATCTTCCTTTCTCGCGAAAATATCAAGTGTTGAGGCACACATTGGAGGAACATGCTCAATCTACGCCTTCAACGCTACCCTGGCAACGTTGCGATCTCTGTAAAGTAGGATTCCTCTGCTCCAGACTCTATGATTGCCATGTAAACACTCAGTGTCACAGCAAGCTGAAGCGGCATCGCTGCCCCAAGTGCCCGGGAAAGTTTATGTGGGCGGAGAATTTGCATGGGCACGCCTGCTCCCACCGAGCAGCGATGCCTGCCCGCCAGATTTTCTGCTCCTTGTGCGACAAATCACTGCCCACCTTGGCCCAGTTGCGTATTCACCTGGTTAGCCACCAAAATATGAGTGGCATCGATCCGGGGCACAGTTCGACCTTCTTTCAGTCGTTCTACCCCAAAGGAGTGGACTGCACCTCGTCGGAGCTTGCTGTCCGCATAGCTGAGGACTTTGAGGTGCAGGATTTCGATCGCTACTACAACGCCTGCACGGGAAGTGGCCAGGAGCTGGATCTGTTCGATTCCGAAACGGAGCAGAGCGGCGATGACCAGGAGGAGAGCGAAAAGACAGCCTCGCATACCTGTCTGCTTTGCGGAGTAGTGACCAACAGACTCCTGAGCCTGCTGCAACACCAGAACAGCGCACATTTAAAGGATCTGCCATGTTCCTGCCAGGATTGTGGTGCTGGCTTTATAAGCGACGCCCTGCTGCAACAGCACAGACGGCGTGTCTGCGCCAAGAAACATTTCCGCCGGCAGTGCCGGAGCTGTAACCTTCGGTTCGTGTGGCCGAGTAACTACGAACAGCATCTGAGGTCCCACCACAGCCAGACGGAGGAAGAGGAGGAGGAACCGGCAGAGGAGCCTGCGCATCGTGAGGCTAGGCTGCAGTGCGACGAGTGCGAAAAGGTCTTCATCTGGCACAAGGATCTCACTCGTCACAAGCGCCTGCACTTGCCGCAGTCGGCGCAGTTCGAGTGCCCGCACTGCGATCGCAAGTTCCACCGCAAGGATGGCCTAAAGTCACACCTGAGGATCCACACAGAAGAACAACTGCTGGAACAGCCCTTAACCTCCGACAATGGTCAGGTCCTGGCCCTGCTAGCTCGTCCTCATGGCTGCAAGCAGATTCAGTGCATGATCTGCCTGTCACGGCACTCCAAGATCTCTGATCTGCGAACGCACCTGGCCTCCCATCAGTACGGACTAAGCTTCTCCACGGAGATCGATATTTCCAGTGTCTCCAAGTCCTTGTACCCAGAATTAGGCATCGTATTGGACAGGGATGAGCTAGCGGATCGGATTATGGCTGATGTGGACCAAGGACTGGAGCTGGATCGATTTATTTCCATCACCAATGAAGCGGGCCTGGAACTCAACTTGGATAGCAGCGAAACGGACACGGAATCTGAGCAGGAGGAAGAGATCCCATCCGGCCAGAACTACGCCTGCAATCTTTGTCCCACGGAGGTAAAGAGAAAGCATAAACTCTATGCCCACCAAGGAGAGGCTCATCAGTGGGAGGACGCACCGTACGTTTGCTTACATTGTCAGGCCAGGTTTGTAAGCGAGTGCCTGCTGCAACATCACTCCCGGACCTTCTGCGGCAATGCCCAGAAGCGCTTCCAGTGCCGCAAATGTCCTCTACGCTACCGCTGGCGGGAGAATCTGAAGCTCCACCTATATCTGTCCCATCAGCAGGCTGAGATGCCAACGGCAGAAGATTTGCCACAGGCGGACGGCGAACTGCAATGCCGGGAGTGCCAGCGAACGTTCAAAATGCAGAAGGATCTCACGCGGCACACTCTGATGCATGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGTGCACGTCGCTTTTACCGCTGGGCCAATCTCCTGCAGCACATCACGCGCCACGGCATCCGGGCTAGCCAGTTGCACTATGCAGAGGCTCTCCTGGACTTCTACGGGAATCCTGGCGGTCAAAAAACGGTGGAGTGCCGGGTGTGCAACGTGAGCTTCTCCAGCATTGCTGCCCTGCGTCTGCATCTGGAGACCATGCCGGCGGGTAGTCACCACGAGCTCTCCTCACTGAAGAACTACTCGATCACCAACCAAATGGGTTTCGAGCTGGAACTCCAGGACTCGGAAACCGATGGGGAGCAGTCCAAACCGGAAGGAGTGCCTGCCTATTACACGTGCGGCATGTGCCAGCTGAGGTGCGTGCGAAAGTTCGAGCTGCACCAGCACCAGCAGGCCATGCACCGGCTGGAGAAGATTCCCGACGGCTGCGATCAGTGCATCTTCAAGAGCGTATGTCCCGATCTCATTGCCCACCATAAGAGGACGCAGTGTGACAATAGGGAGAAGCAGTTCACGTGCTCTCGCTGCGGCTACAAGTTCATGTGGGAGTCAAATCTGCTGGCGCACATGCAGCTGCAGCACGGAAAGCCGGACAACCCGGAGCAGGAGGAGGGTAAGGAGGCTTCAGTGGAGGAACCGAAGCCTGACTGCCCGGTGTTCCAGTGTGCCCTCTGCCCCAGGAAGTATAATCGAAAGGATCGCCTTACGGCGCACGTGAAAAAGTTCCATGGGCCCGATGGCAGGGGCCCCGATGTGGTAAAGGTTCCTCCGAACCGATCCAGCTCCCCCAAGGAACCAAAGCGCTTCCTGTGCGCCTTCTGCGGCAAGGCGGTCAGCTCATCCTCCAATCTGATCATTCACATGCGCCGCCATACCGGCGAAAAGCCTTTCAAGTGCGAGTTCTGCGCAATGGCCTTTCCCCGATCCTCGGACCTCCAATGCCACCGTCGCACGCATACTGGGGAGCGGCCGCACGTGTGTACCGTCTGCCAGAAAGGATTCGCTCGCTCCTACAAGTTGCAGCAGCACATGCGTATCCATAGCGGCGAGCGGCCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACGCAGTCCAACGACCTGACACTGCACATCCGTCGGCATACAGGCGAGCGGCCCTACCTGTGCGGCGTCTGCGGGGAACGCTTCATCCAGGGAACGGCGCTGAAGAATCATCGCCTGCAGCAGGGCCACTATGAGGAGGGTCAGAATTCTGGGGAGCCGGCGAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence
MLPSNICRTCAVQNKDLRPLSSCLGKDASKTFYDVLQELTQIDPLEESSDDNLPQHLCTDCLASLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQKIIKTEVDIDEATPKCDVDVDNAEISPVEFKWQLKSDSDEDSAGAGASDENEVERKPYPLRRSARKIKLPVESDNEDSTLAEIVPIKRRRGRPPGSAKRQSMTPDGRHACKVCGKTFSWFRDMQRHARIHFEKSNAYVCDTCGKGFLRKDKYSFHLRCHEKREAKSKALQLASEWRFAERLYNSGRLKRIECKLCGLKCLRIQELRIHLVSHGKVESLLQLTEDSDVIREHYADQPCNLEGVRQQIIKDIAAGQLDKFCSVVNFHGYELGVCDSDEEATSAESKYECTACNLPFSRKYQVLRHTLEEHAQSTPSTLPWQRCDLCKVGFLCSRLYDCHVNTQCHSKLKRHRCPKCPGKFMWAENLHGHACSHRAAMPARQIFCSLCDKSLPTLAQLRIHLVSHQNMSGIDPGHSSTFFQSFYPKGVDCTSSELAVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDQEESEKTASHTCLLCGVVTNRLLSLLQHQNSAHLKDLPCSCQDCGAGFISDALLQQHRRRVCAKKHFRRQCRSCNLRFVWPSNYEQHLRSHHSQTEEEEEEPAEEPAHREARLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRIHTEEQLLEQPLTSDNGQVLALLARPHGCKQIQCMICLSRHSKISDLRTHLASHQYGLSFSTEIDISSVSKSLYPELGIVLDRDELADRIMADVDQGLELDRFISITNEAGLELNLDSSETDTESEQEEEIPSGQNYACNLCPTEVKRKHKLYAHQGEAHQWEDAPYVCLHCQARFVSECLLQHHSRTFCGNAQKRFQCRKCPLRYRWRENLKLHLYLSHQQAEMPTAEDLPQADGELQCRECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHITRHGIRASQLHYAEALLDFYGNPGGQKTVECRVCNVSFSSIAALRLHLETMPAGSHHELSSLKNYSITNQMGFELELQDSETDGEQSKPEGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCDNREKQFTCSRCGYKFMWESNLLAHMQLQHGKPDNPEQEEGKEASVEEPKPDCPVFQCALCPRKYNRKDRLTAHVKKFHGPDGRGPDVVKVPPNRSSSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYLCGVCGERFIQGTALKNHRLQQGHYEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00491633;
90% Identity
iTF_00525995;
80% Identity
-