Basic Information

Insect: Drosophila kanapiae
Gene Symbol: ZNF296
Assembly: GCA_008042475.1
Location: VNJM01001679.1:9179-13665[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0017 0.14 12.8 1.5 1 23 210 232 210 232 0.96

2 25 1.8 1.4e+02 3.3 3.6 1 16 239 254 239 261 0.79

3 25 0.074 5.9 7.6 0.7 2 23 293 314 292 314 0.95

4 25 0.0048 0.38 11.3 0.2 1 23 387 410 387 410 0.94

5 25 2 1.6e+02 3.1 2.7 1 23 451 473 451 473 0.96

6 25 0.052 4.1 8.1 0.0 3 23 486 506 484 506 0.95

7 25 0.041 3.3 8.4 0.4 1 23 586 609 586 609 0.96

8 25 0.0094 0.75 10.4 0.8 2 22 616 636 615 636 0.93

9 25 0.038 3.1 8.5 1.9 2 23 646 667 645 668 0.94

10 25 0.0024 0.19 12.3 1.5 2 23 690 711 689 711 0.97

11 25 4.9e-06 0.00039 20.8 4.3 1 23 718 740 718 740 0.98

12 25 0.022 1.7 9.3 0.5 1 23 875 898 875 898 0.90

13 25 0.21 17 6.2 3.3 1 21 905 925 905 926 0.94

14 25 0.022 1.8 9.3 1.4 1 23 935 958 935 958 0.93

15 25 8.2e-05 0.0065 16.9 2.3 2 23 977 998 976 998 0.97

16 25 0.00011 0.0089 16.5 0.9 1 23 1005 1027 1005 1027 0.98

17 25 0.039 3.1 8.5 0.0 2 21 1054 1073 1053 1074 0.92

18 25 0.034 2.7 8.7 4.0 1 23 1120 1143 1120 1143 0.96

19 25 0.0077 0.61 10.7 0.8 1 23 1180 1203 1180 1203 0.96

20 25 0.00038 0.031 14.8 1.4 1 23 1229 1252 1229 1252 0.97

21 25 5e-06 0.0004 20.7 0.2 2 23 1279 1300 1278 1300 0.95

22 25 0.0025 0.2 12.2 2.6 1 23 1306 1328 1306 1328 0.99

23 25 2e-06 0.00016 22.0 2.0 1 23 1334 1356 1334 1356 0.97

24 25 1.7e-07 1.4e-05 25.3 2.4 1 23 1362 1384 1362 1384 0.99

25 25 0.0012 0.093 13.3 0.1 1 21 1390 1410 1390 1414 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0017	0.14	12.8	1.5	1	23	210	232	210	232	0.96
2	25	1.8	1.4e+02	3.3	3.6	1	16	239	254	239	261	0.79
3	25	0.074	5.9	7.6	0.7	2	23	293	314	292	314	0.95
4	25	0.0048	0.38	11.3	0.2	1	23	387	410	387	410	0.94
5	25	2	1.6e+02	3.1	2.7	1	23	451	473	451	473	0.96
6	25	0.052	4.1	8.1	0.0	3	23	486	506	484	506	0.95
7	25	0.041	3.3	8.4	0.4	1	23	586	609	586	609	0.96
8	25	0.0094	0.75	10.4	0.8	2	22	616	636	615	636	0.93
9	25	0.038	3.1	8.5	1.9	2	23	646	667	645	668	0.94
10	25	0.0024	0.19	12.3	1.5	2	23	690	711	689	711	0.97
11	25	4.9e-06	0.00039	20.8	4.3	1	23	718	740	718	740	0.98
12	25	0.022	1.7	9.3	0.5	1	23	875	898	875	898	0.90
13	25	0.21	17	6.2	3.3	1	21	905	925	905	926	0.94
14	25	0.022	1.8	9.3	1.4	1	23	935	958	935	958	0.93
15	25	8.2e-05	0.0065	16.9	2.3	2	23	977	998	976	998	0.97
16	25	0.00011	0.0089	16.5	0.9	1	23	1005	1027	1005	1027	0.98
17	25	0.039	3.1	8.5	0.0	2	21	1054	1073	1053	1074	0.92
18	25	0.034	2.7	8.7	4.0	1	23	1120	1143	1120	1143	0.96
19	25	0.0077	0.61	10.7	0.8	1	23	1180	1203	1180	1203	0.96
20	25	0.00038	0.031	14.8	1.4	1	23	1229	1252	1229	1252	0.97
21	25	5e-06	0.0004	20.7	0.2	2	23	1279	1300	1278	1300	0.95
22	25	0.0025	0.2	12.2	2.6	1	23	1306	1328	1306	1328	0.99
23	25	2e-06	0.00016	22.0	2.0	1	23	1334	1356	1334	1356	0.97
24	25	1.7e-07	1.4e-05	25.3	2.4	1	23	1362	1384	1362	1384	0.99
25	25	0.0012	0.093	13.3	0.1	1	21	1390	1410	1390	1414	0.91

Sequence Information

Coding Sequence: ATGCTTCCATCAAATATCTGCCGCACTTGTGCGGTTCAGAACAAAGATTTGCGGCCCTTGTCCACCTGTCTGGGCAAAGACGCCTCCAAAACATTCTATGATGTGCTCCAAGAGCTAACCCAGATCGATCCTCTGGAAGAGAGCTCGGATGACAATCTGCCGCAGCATCTCTGCACTGACTGCTTGGCGAGTTTGGAAAGTGCCTACGCCTTTGTGGAACAGGCCCGGAAGGTCAATGGCGAGCTGTTGGTTCGCTTGCGGAGATGCCTCGACGAAATGCCCATTGACATaccgcaggagcagcagcagctcattaAAACCGAAGTGGATATAGATGAGGCGACTCCCAAGGGTGATGTGGATGTAGATAAAGCAGGAATATCGCCTGTGGAGTTCAAATGGCAGCCGGAAAGTGACAGCGATGAGGAAtctgctggagcagcagccagtgaTGAGAATGAGGTGGAGAGGAAGCCCTATCCTCTTAGGCGTAGTGCGCGAAAAATCAAGCTACCAGTGGAGAGCGATAATGAGGAGTCACCTTTAGCAGAGCTCGCCCCCATTAAACGCCGTCGTGGCCGACCGCCTGGCCCCGCCAAGCGCCAGGGCATGACCCCCGATGGACGCCACGCCTGCAAGGTGTGCGGCAAGACCTTCTCCTGGTTTCGCGACATGCAGCGTCATGCCCGCATCCATTTCGAGAAATCCAACGCCTACGTTTGCAATACCTGCGGCAAGGGATTCCTGCGCAAGGACAAGTACTCCTTCCACTTGCGCTGCCACGAAAAGCGCGAGGCCAAGACCAAGGCTCTCCAGCTGGCCAGCGAATGGCGCTTCGCCGAGCGGCTGTACAGTTCCGGCAGGCTGAAAAGGATCGAGTGCAAGCTGTGTGGTCTGAAGTGCCAGCGAATTCAGGAGCTGCGAATTCACTTGGTCAGCCATGGGAACGTAGAGAGCTTGCTCCAGTTGACGGAGGATAGCGATGTGATCAGGGAGCACTATGCCGACCAGCCCTGCAGCTTGGAAAGCGTCAGGGAACAAATTATTAAGGACATAGCGGCAGGACAGCTGGATAAGTTCGCTTCCGTGGTAAATTTCCATGGCTATGAGCAAGGAGTGTGTGACTCGGACGAGGAAGCGGCTAGCGGAGAGTCCAAGTACGAGTGCGGGGCGTGCAATCTTCCCTTCTCGCGAAAATATCAAGTGTTGAGGCACACACTGGAGGAACATGCTCAAGCTACGCCTTCAACGCTGCCCTGGCAACGCTGCGACGTCTGTAAAGTAGGATTCCTCTGCTCCAGACTCTACGATTGCCATGTGAACACTCAGTGTCACAGCAAGCTGAAGCGGCATCGCTGCCCCAAGTGCCCGGGAAAGTTTATGTGGCCGGAGAATCTGCATGGGCACGCCTGCACCCACCGCAACGAGGTAGCAACGCCTGCCCGTCAGATCTTCTGTGCCTTGTGCGACGAATCACTGCCCACCTTGGCCCAATTGCGTATTCACCTGGTTAGCCACCAAAATATGAGTGGCATCGATCCGGGACACAGTTCGACCTTCTTTCGGTCGTTCTACCCCAAAGGAGTGGACTGTACCTCGTCGGAGCTTGCTGTACGCATAGCTGAGGACTTTGAGGTGCAGGATTTCGATCGTTACTACAACGCCTGCACGGGAAGTGGCCAGGAGCTGGATCTCTTCGATTCCGAAACGGAGCAGAGCGGTGATGACCAGGAGGAGAGCGAGAAGACCGCCTCGCATACCTGTCTGCTGTGTGGTGTGGTGACCAACAGACTCCTAAGCCTGCTGCAGCACCAGAACAGCGCACATTTAAAGGATCTGCCATGTTCCTGCCAGGATTGTGGTGCTGGCTTTATAAGCGACGCCCTGCTGCAACATCACCGACGGCGTGTCTGCGCCAAGAAACATTTCCGCCAGCAGTGTCGGAGCTGTAACCTTCGTTTCGTTTGGCCGAGTAACTACGAACAGCATTTAAGGTCCCACCACACCCAGggggaggaagaggaggacgaACCGGCAGAGGAGCCTGCGCATCGGGAGGCGAGGCTACAGTGCGACGAGTGCGAAAAGGTCTTCATCTGGCACAAGGATCTCACGCGTCACAAGCGCCTGCACTTGCCGCAGTCGGCGCAGTTCGAGTGCCCGCACTGCGATCGCAAGTTCCACCGCAAGGACGGCCTTAAGTCACACCTGAGGATCCACACAGAAGAACAACTGCTGGAGCAGCCCTTCACCTCCGACAGTGGTCAGGTCCTGGCCCTGCTAGCTCGTCCTCATGGCTGCAAGCAGATTCAATGCATGATCTGCCTGTCACGGCACTCCAAGATCTCTGATCTGCGAACGCACCTGGCCTCCCATCAATACGGACTGAGCTTCTCCACGGAAATCGATACTTGCAGTGTCTCCAAGTCCTTGTACCCAGAATTGGGTATCGTCTTGGACAGGGATGAGCTAGCGGATCGGATTATGGCTGATGTGAACAAAGGACTGGAGCTGGATCGATTTATTTCCATCACCAATGAGGCGGGCCTGGAGCTCAACTTGGATAGCAGCGAAACGGACACGGAATccgagcaggaggaggagatccAATCTGGCCAGAACTACGCCTGCACTCTTTGCCCCACGGAGGTAAAGAGAAAGCATAAACTCTATGCCCACCAAGGCGAGGCTCATCAGTGGGAGGACGCACCCTTTGTTTGCTTACATTGCCAGGCCAGGTTTGTCAGCGAGTGCCTGCTGCAACATCACTCCAGGAACTTCTGCGACAATGCCCAGAAGCGCTTCCAGTGCCGCAAATGTCCTCTACGCTTCCGCTGGCGGGAGAACCTGAAGCTCCACCTATATCTGTCCCATCAACAGGCTGAGATGCCAACGGCAGAGGACTCGCCACAGGCGGATGGCGAACTGCAATGCCGCGAGTGCCAGCGAACATTCAAAATGCAGAAGGATCTCACGCGGCACACGCTGATGCATGCCCGGGAGGCGACAATCTATCGGTGCCGCTGGTGTGCACGTCGCTTCTATCGCTGGGCCAATCTCCTGCAGCACATCACGCGCCACGGCATCCGAGCTAGCCAGCTGCACTATGCGGAGGCTCTCCTGGACTTCTATGGGAATCCTGGCGGTCAGAAAACGGTGGAATGCCGGGTGTGCAATGTCAGCTTCTCCAGCATTGCTGCCCTGCGTCTGCATCTGGAGAGCATGCCGGCGGGGAGTCACCACGAGCTCTCCTCACTGAAGAACTACTCGATCACCAACCAAATGGGTTTCGAGCTGGAACTCCAGGACTCGGAAACCGATGGGGAGCAGTCGAAACCGGAAGGAGTGCCTGCCTATTACACGTGCGGCATGTGCCAGCTGAGGTGCGTGCGAAAGTTCGAGctgcaccagcaccagcaggccATGCACCGCCTGGAGAAGATTCCCGACGGCTGCGATCAGTGTATCTTCAAGAGCGTCTGTCCAGATCTCATTGCCCACCACAAGAGGACGCAGTGTGGCAATCGGGAGAAGCAGTTCACGTGCTCTCGCTGCGGTTACAAGTTCATGTGGGAATCGAACCTGCTGATGCACATGCAGCTGCAGCACGGTAAGCCGGACAACccggagcaggaggagggtAAGGAGGCTTCGGTAGAGGAACCAAAGCCTGACTGTCCGGTTTTCCAGTGTGCCCTCTGCCCCAGGAAGTATAATCGAAAGGATCGCCTTACGGCGCACGTTAAAAAGTTCCATGGGCCCGATGGCAGGGGTCCCGATGTGGCAAAGGTTCCCCCCACTCGATCCAGCTCCCCCAAGGAACCGAAGCGCTTCCTGTGCGCCTTCTGCGGCAAGGCGGTCAGCTCCTCTTCCAATCTGATCATTCACATGCGCCGCCATACCGGCGAAAAGCCTTTTAAATGCGAGTTTTGCGCAATGGCTTTTCCGCGATCCTCGGACCTCCAATGCCATCGCCGGACGCATACTGGGGAGCGGCCGCACGTGTGTACCGTCTGCCAGAAGGGATTCGCTCGCTCCTACAAGCTGCAACAGCACATGCGTATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACGCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACTGGCGAGCGGCCCTACCAGTGTGGCGTCTGCGGGGAACGCTTCATCCAGGGAACGGCGCTGAAGAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAATTCTGGGGAGCCGGCAAGGCGCACGGTTTTGGAACAGTTTACTGTATGA
Protein Sequence: MLPSNICRTCAVQNKDLRPLSTCLGKDASKTFYDVLQELTQIDPLEESSDDNLPQHLCTDCLASLESAYAFVEQARKVNGELLVRLRRCLDEMPIDIPQEQQQLIKTEVDIDEATPKGDVDVDKAGISPVEFKWQPESDSDEESAGAAASDENEVERKPYPLRRSARKIKLPVESDNEESPLAELAPIKRRRGRPPGPAKRQGMTPDGRHACKVCGKTFSWFRDMQRHARIHFEKSNAYVCNTCGKGFLRKDKYSFHLRCHEKREAKTKALQLASEWRFAERLYSSGRLKRIECKLCGLKCQRIQELRIHLVSHGNVESLLQLTEDSDVIREHYADQPCSLESVREQIIKDIAAGQLDKFASVVNFHGYEQGVCDSDEEAASGESKYECGACNLPFSRKYQVLRHTLEEHAQATPSTLPWQRCDVCKVGFLCSRLYDCHVNTQCHSKLKRHRCPKCPGKFMWPENLHGHACTHRNEVATPARQIFCALCDESLPTLAQLRIHLVSHQNMSGIDPGHSSTFFRSFYPKGVDCTSSELAVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDQEESEKTASHTCLLCGVVTNRLLSLLQHQNSAHLKDLPCSCQDCGAGFISDALLQHHRRRVCAKKHFRQQCRSCNLRFVWPSNYEQHLRSHHTQGEEEEDEPAEEPAHREARLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRIHTEEQLLEQPFTSDSGQVLALLARPHGCKQIQCMICLSRHSKISDLRTHLASHQYGLSFSTEIDTCSVSKSLYPELGIVLDRDELADRIMADVNKGLELDRFISITNEAGLELNLDSSETDTESEQEEEIQSGQNYACTLCPTEVKRKHKLYAHQGEAHQWEDAPFVCLHCQARFVSECLLQHHSRNFCDNAQKRFQCRKCPLRFRWRENLKLHLYLSHQQAEMPTAEDSPQADGELQCRECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHITRHGIRASQLHYAEALLDFYGNPGGQKTVECRVCNVSFSSIAALRLHLESMPAGSHHELSSLKNYSITNQMGFELELQDSETDGEQSKPEGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCSRCGYKFMWESNLLMHMQLQHGKPDNPEQEEGKEASVEEPKPDCPVFQCALCPRKYNRKDRLTAHVKKFHGPDGRGPDVAKVPPTRSSSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYEEGQNSGEPARRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00569809;
80% Identity: -