Basic Information

Insect: Drosophila parthenogenetica
Gene Symbol: -
Assembly: GCA_035047505.1
Location: JAWNPM010000174.1:5777902-5783220[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.3e-15 7.7e-12 44.8 0.0 6 73 424 487 420 490 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.3e-15	7.7e-12	44.8	0.0	6	73	424	487	420	490	0.89

Sequence Information

Coding Sequence: ATGAGTCTGCCGAATCCAAATGTGGACAAGGGTATTTGTGGCCCAAAGCAGTCGTTTAACCTGAGCAGTTCCAGCAACGATTCAGCTCCGACTAACAACGGCTTCAATCACAATGCACATGGGCAATTGTATGAATCGGACATTTCGCAGCCGTTGCCAGGAGCACAGCACAGTGCCATCGAGAATGGTGGCACTTCAAGCAACCGCAAATCGAAGAAACATAAGAACAAGAAATCAAAGAAGCGTCGCGATTCAAAGGAAGTTGCTCTTGTCGGCTGGAATGGCGCTTTTCCGAATCTTTCGTCCACCCACAGTCTCGAGAGTAACTCGGATGTGGATGTTTCGCAGCTGCCGGCTGATCTAAAGGCTATAGGTGCCACTGGCTTAAGCGTCTTCCCCAGGGAGGAGCCgccccaacaacagcagcagttaccGCTGCCTTCGACTTCGCCGCCGCCCTTGTTGTCGTCGTCTCCGTCAACTTCGTCTTCTTCTCCTACCACTACTCACTCCTCCTCGCCGGTTTTACCTGACAAAACTTCCGagataccaacaacaaccacaacaagttcaacaacaacaatcacagcgacaacaacaacaagttgtaCAATTAATAATTCGACTGCATCATCCAGTCCCAAGTCCAACATGAACTACAGTACAGCCTCGATTGGTTGCCCAACTTCAGAACCATCATCAGAGCTTGAAAATGTAGCAGAACCTGAACATGAACCTGAACCACAACCAGAATCTGAATCAGAAACACTCACTGATTTCTCAAGCCAGACACACAAGAGTCACAAAAAAATTCGACGAGAGCACGCTGGTGAAAAGGTGTCCGCAACACCACCTCCGAAGGCTCCTAGGACTGAAGAATCTTTGAATGCAGCTGCAgactctgcctctgcctctgcctctttcTCGGCTATGACTGGCAACAGGGAGTCACGTAAACGTCCTCCTTCCAACACACTTAATAGTTCACCCATCGAACAGCTGGAGAATGATTTTAAACGTGTGAAGACATCAAAGTCGGAGGAGGGCTCACCGCCATTTATACCCACAATGCGTCAACGATCCAAATCCTTCTTTCAGGTAAACCCAGAGATGGTGCCACGTGTGACACGTTCCCGCAGCATTTGTGCCAGCAATATCTCGGATCTTGATGAGATCAAGGTGGCCAAGATGGCGCCAGTGAATCCGGGCCGTAAGGTGCCCGAGAGACGTCGCTCCATGGCAGCTAATAAGCTGCCCGTGACCGATAAATACTATTGCTTGCCCTTCAAGTACGGCTGGAAACGTGAACTTGTCCTGCGCAGCAATGCCTCCTTGTCCCGTCAACGTGGAGATGTTATATTCATATCGCCAGCTGGCAAAAAACTGCGCTCCCGTGATGATATTATACCGCTACTATCTGGTGAACTCACCATCGATCATTTCTGCTTCCAACGGCAAATGCAACAAGCCGGCGATGAATTTGAATCTGTGCGTCAAGCTCAACCGGCAATGGCACGCCGCAAATCGATGGCTGCTGCCAAGcaagtgcaacagcaacagacacAGCAAATGCatcaacagctgcagcaacaaccgaatatacagcaacaaaatgtgcaGCAACCCAAAGTACAACAACAGAatctacagcaacaacaacagcagcagcacaataTACATAAGCGCACACCTGCCTCTGGCAAACGTGTGCCCAAGCCGAAGGTGCCAAAGGGCGCTAGTCCTCCTCCAGAGGGTTGGACATCCACAATGGCCGTTAAGGGTAATGCACGTGTCCTGGccgccagcaacagcaattccGGAGGAGGATCCGGATCCAGTGCCAATCAAAATTCACGCAAACGCAGCAATCAATCGACCAAATCACCAAAGATACAACCAGCAGTGCTGCCGTTGCAGCCCAAGCCTCAAACTCCGGCTCCAGCTCCACCGCTGGCAACTCCCCAATTGCAGACTCAACGTCAATCTCAAGTGAATGCTTCTCAGCTGCAACCGCAACGTCAATCCCAAACTGCTATTCAAGCTCAAGTACAAGCGGCAGCACAAGTCCCGACTCAATCTCAAGCTGGTGCACAGCCTCAGGCTCAGTTGGGTCCACAGAAACTAGTGGATAATCGTATGATATGTGTCTATTGTCTGCAGTCGATCAACGAAAAGGAGAGAGCTTATTCTCTTGGTTcgaacaaagccaaaaactatATTTGTCAGCTTTGTATCAAACCCGTGAGAACTGTGTTGCATCCGCAGACAGAAGGAGAAGTAGCGGATGCCGAAAATCAGCCGGAAAATGAACCAAGCGATGAAAATACCAATGCCAATGTCAATACCAATGCTAGCGCTAATGCTGGTAACAACTTTGCTACAAAGGAAGCCCTTTATGAGCAAAACGGTGATAGCAATGGCAGCATGTTGGGTATTGCCGAGGAGATTGAATTACCTGGTGAATTGCCACCAGCTCAGCTACTTAGCGATAATACGCACATTTCACGTGCCGGCAATAAGATCACGCCAAAGCCCCAGGAAATCGTTGTCATTAATGGACGCAAGGCACTTGCCATCGCTGGCGAACCTCCGCGTCCACGTTTACAAGTCATACCACGTGAGCCGAACTTGGAGCTGTATGAAAAGCACTATCGTCCCAAGCATCTTCGGCACTCGAGCAGCAAGGAAAAGCGGCAGGGCTTATTGGAAAGCATGTCAGCTGGTATTCAGAGCTGTCAGGTGATGTCGGCTGTGATGAAAACTCTTGATCTGCATGATCGAGTGCGTATGTCTTATGTGTGCAAGACTTGGGCCATGATTGGTCGCGATCGCAGTGTTTGGCGTACTTTGAAGCTGCGCAATACGCACATTAACAACTGGGTCTATTGTATGCGTGACATGGTGCGTAATCGCACTCGGGAACTGGACATGATAGGCTGCAAGTGGGCGAGTCCCAAGCTGCGCATGGAGGGTGATTTACGTGTGTTGAAATCACTGCGTATTTTACGTACTGATGCGTGTGAAGCTGATTTTATGAACTTGATCTTTAAGCGTCTCACgcgactgcagcagctgcgTGCCACATGCACCAGCCGTGGTCTTAGCTTGACCAACATTGATAGAATGGTGGATCTGCAAGTGTTGCGTATTCGCATGACTGAGCCGAAGGCAACCATTTCATCGCTGCAACCGTTGCAGAAGCTAGAGAATCTGCGTGAACTGAGTCTGCGTGGCATCAACAACATGTCCCAGCTGgatttgctgcagctgcagggATTGACGAAACTGGAGACATTGATACTCGGCTCCTGTCGTGGCATGAAGGTGGCTGCCTTTGGGGATCAAGTGTTGCCCAATCTAAAGCGTCTGCGTCATCTGCGCCTCGAGAATCATCCTAGCAATCGTTCGTTTAATATTACTGAGATCATGAAGGGCTTGGCCATTGCTAGTCCTGCTAGCGGTGATGGTGTCAAGCGTCTCGAACTCATCAATGTCAATGTGGATGAAGAGTTTAGTCGTCAGCTTGGTGTATGTAAATCCGTTGAGGAGTTGCTTTTGATGCCAAATTTCCACAACAATACAGCCAACATGATGCACTACGTCATGCAGGCCATCAATGAGAACAGCGAGCAGCTTAAAGTCTTTCGCTTGGGCATTACCTTTGAGCTTCTGAGCGTTACGCGTGCACTGGCCATGAATCAGGAAAAGGATTGTATTCCGGTGGCATTGCCGATACCCGGAGTGCCTGAGAACGACATGCTTAATCAGTCGGATGAGACAATTGCCTATCTGCCAGTGGACCGACTAGAGTCAATACTGCACCACATGATGCCACAGGCTTGGCTAACTGTTGCCAAGGTATCGCAAAGCGAGACAACTAACTTGAAATTCCTTATGGCCTCGCCAAACAATGATTCTGGTGGTGGTGCTAATAACAACTAA
Protein Sequence: MSLPNPNVDKGICGPKQSFNLSSSSNDSAPTNNGFNHNAHGQLYESDISQPLPGAQHSAIENGGTSSNRKSKKHKNKKSKKRRDSKEVALVGWNGAFPNLSSTHSLESNSDVDVSQLPADLKAIGATGLSVFPREEPPQQQQQLPLPSTSPPPLLSSSPSTSSSSPTTTHSSSPVLPDKTSEIPTTTTTSSTTTITATTTTSCTINNSTASSSPKSNMNYSTASIGCPTSEPSSELENVAEPEHEPEPQPESESETLTDFSSQTHKSHKKIRREHAGEKVSATPPPKAPRTEESLNAAADSASASASFSAMTGNRESRKRPPSNTLNSSPIEQLENDFKRVKTSKSEEGSPPFIPTMRQRSKSFFQVNPEMVPRVTRSRSICASNISDLDEIKVAKMAPVNPGRKVPERRRSMAANKLPVTDKYYCLPFKYGWKRELVLRSNASLSRQRGDVIFISPAGKKLRSRDDIIPLLSGELTIDHFCFQRQMQQAGDEFESVRQAQPAMARRKSMAAAKQVQQQQTQQMHQQLQQQPNIQQQNVQQPKVQQQNLQQQQQQQHNIHKRTPASGKRVPKPKVPKGASPPPEGWTSTMAVKGNARVLAASNSNSGGGSGSSANQNSRKRSNQSTKSPKIQPAVLPLQPKPQTPAPAPPLATPQLQTQRQSQVNASQLQPQRQSQTAIQAQVQAAAQVPTQSQAGAQPQAQLGPQKLVDNRMICVYCLQSINEKERAYSLGSNKAKNYICQLCIKPVRTVLHPQTEGEVADAENQPENEPSDENTNANVNTNASANAGNNFATKEALYEQNGDSNGSMLGIAEEIELPGELPPAQLLSDNTHISRAGNKITPKPQEIVVINGRKALAIAGEPPRPRLQVIPREPNLELYEKHYRPKHLRHSSSKEKRQGLLESMSAGIQSCQVMSAVMKTLDLHDRVRMSYVCKTWAMIGRDRSVWRTLKLRNTHINNWVYCMRDMVRNRTRELDMIGCKWASPKLRMEGDLRVLKSLRILRTDACEADFMNLIFKRLTRLQQLRATCTSRGLSLTNIDRMVDLQVLRIRMTEPKATISSLQPLQKLENLRELSLRGINNMSQLDLLQLQGLTKLETLILGSCRGMKVAAFGDQVLPNLKRLRHLRLENHPSNRSFNITEIMKGLAIASPASGDGVKRLELINVNVDEEFSRQLGVCKSVEELLLMPNFHNNTANMMHYVMQAINENSEQLKVFRLGITFELLSVTRALAMNQEKDCIPVALPIPGVPENDMLNQSDETIAYLPVDRLESILHHMMPQAWLTVAKVSQSETTNLKFLMASPNNDSGGGANNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00470866;
90% Identity: -
80% Identity: -