Basic Information

Insect: Drosophila paranaensis
Gene Symbol: ush
Assembly: GCA_035047545.1
Location: JAWNPL010000153.1:8527977-8536195[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0066 0.45 11.1 0.0 1 20 181 200 181 202 0.90

2 9 0.00028 0.019 15.4 0.8 1 23 257 279 257 279 0.98

3 9 0.051 3.4 8.3 1.0 2 21 324 343 324 344 0.92

4 9 0.049 3.3 8.4 2.9 2 21 725 744 724 745 0.93

5 9 0.0091 0.62 10.7 0.0 3 21 793 811 791 812 0.91

6 9 0.0066 0.45 11.1 0.0 2 23 871 892 870 892 0.98

7 9 0.0039 0.26 11.8 1.3 1 23 898 920 898 920 0.99

8 9 0.0014 0.092 13.3 1.9 1 23 975 998 975 998 0.96

9 9 0.31 21 5.9 0.7 2 20 1105 1123 1104 1125 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0066	0.45	11.1	0.0	1	20	181	200	181	202	0.90
2	9	0.00028	0.019	15.4	0.8	1	23	257	279	257	279	0.98
3	9	0.051	3.4	8.3	1.0	2	21	324	343	324	344	0.92
4	9	0.049	3.3	8.4	2.9	2	21	725	744	724	745	0.93
5	9	0.0091	0.62	10.7	0.0	3	21	793	811	791	812	0.91
6	9	0.0066	0.45	11.1	0.0	2	23	871	892	870	892	0.98
7	9	0.0039	0.26	11.8	1.3	1	23	898	920	898	920	0.99
8	9	0.0014	0.092	13.3	1.9	1	23	975	998	975	998	0.96
9	9	0.31	21	5.9	0.7	2	20	1105	1123	1104	1125	0.91

Sequence Information

Coding Sequence: ATGCAACTGCTGAAAGATTCCAAAGATCTGGGCGCACACGAGCTGAGCgaggagaagcagcagcaacagctggaggagcagcccGAGgacgagcagctggagcagcacgCCAGCAGCGCCTCTGAGCAGCTCGAGGAGACCGACATGGATCAGGAACTGGCCGAAGAGGAGCCAGTGGCGGCCAGTGCACAACAGCAAAACGCAGCCGACAGCTCGACGACTCCGCCTCGCAGTCCCACGCCCCCGGAGCTGGTGCCCAAGCTGGAGCGAGCCGATTCGCCGGCCACGCCGCCTTCAGTGGCCGCTACGCCCAGTCCTCCACCGACGCCAACGCCGCCGCTAGTGCTGCCCAAGCTGCGGCTCAATGCGCTGCTCGCCTCCGATCCGGCGCTCAAGCCCGACGCCAAGGAGCTCAATCTGGAGCCACGCCTGCTCGGCCCACCCCCACAGCTGGCCAAGcccgagcagcaacagcagcagcagcagcagagcttgCCCGATCCCAGCAGCCTGGTGGAGCCGCTGCTCAAGCCGGCGCGCTTCATGTGCCTGCCCTGCGGCATAGCCTTCAGCTCGCCCTCCACGCTGGAGGCGCACCAGGCCTACTACTGCTCGCACCGCAACAAGGATGCGGACGAGGACTCGGCCGGGGGCGACaaggcagcagctggagctggcggtGGCTCAAATGCCACTGCCAGCAGCGGctccagcggcggcagctccgGCTCGGAGCCACCCGCCAAGATGGCGCGCACGGGCAAGCAGTACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCACCAGACCTCGCCGGCCGCGCCCACCCTCAACAGCCTCTCCGGGCTGGCGGCCAATGGCGtggtcgccgccgccgctgccgccgccgctgcggtCAATGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCGCGCCGCAGCGACGGACAGCTGACGCCCAAGCCCGAGGCGAGTGCCAACAGCAACTCTGCAGGCCCTGCAGTGGGTGgatccgctgctgctgctgctgcagctggggtCAAGCTCAGCGGCGCTCACAGCCCGCAGACACGCAACAAGACGCCGACGCCGGCAAtggtcgctgctgctgcggctgcggcggccgctgctgcagctgccgcctcGCTGCAGGTGGCACCGCCGCAGCCCTTCCTGGCGCTGCCCACCAATCCCATCATCATAGTGCCCTGTTCGCTGATACGTGCCGCCAGCCTCATTCCAGGACCACTCACCACCTCCACGTCGGGCATTGTCAATCCGGAGTCCACATGCTTCACCCTCGACAACGGCGCACTCAAGCCGCTGGCCACGGCGCTCAGCATCAATGCGTTGACAGGCaacgccacgcccacgcccacacccatgCCCAGCAGCAGTCAGCTGAGCATGCCGGCTCTGGAGCCGGAGCGTCACAGCGCAGGCAGCCTCCTGGAGACGGAGGCCAAGAGCAGTCCGCCGGAGCCCAAGCGCAAGGAAGCCAGCGGCATGCGCGAAACCACGCCCCTGGACCTATCGCTGCGTCGGTCGCCCATTTCGCCGCTACTGCAGCGCCAGCGGCTGATGGAGGAGGCGCTACTCAGCGCCGGCAAGGAGAACATGGAGAGCAGTGCCCGCACCGGAGGCAGCGTTACGCCGGAGCAGATTGTGTGCGCGCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGACGCGCGATCAGCCCACGCAGCTCAGGCGCGGGCAGCGCTGCCTCCATGTCGCCTCCAGCGCTGGCCGTGCCCCATCTGCTGGACAATCTGCAGCCATTGCGCTCGATGCTGCCCGCCGACTTTGCGCTCTCCGAGTCACTGCTGGCTAAGACCAATCCGGAGCTGGCGCTCAAGctggcagcagccgctgccgcagccgtggcgggcagcagcagcgctgagCTGGCCAGCAAGCTGGGCTTCAGCCCACAAACGGGCGCCGCCCCTCCTCCGGCTGTGGCCAACGTGGCCGCCAATGCGCCCAGCAGCCAGCCGCAGATCTACGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATCGTCTTCTGCAAATACGAGAACTATCTGGCCCATAAGCAGCACTACTGCTCCGCCCGCAACCAGGACACTGGTGCGGATGGGGACTCCAAGCACGCCGTGACTCCGCCCGCCGCAGCGGGTCCAGGCGCAGTTGCGGGCGCTTCCTCGCTGGAGACCACGCCCGTGGCCTATCAGCAGCTGATCTGCGCTGCCTGCGGCATTAAGTACACCTCGCTGGACAATCTGCGCGCCCACCAGAACTACTATTGCCCCAAGGGCGGGGCGGCGGCCACGCCCGCGGAGGCAGCCACGccacagctgccgctgcccaagGAGAAGTGCGTCAAGTGCAAGACGCTGCATGAGCACGGCCAGCCGTGTCCCACGCCCCCGGCCACGCCCCAGCTGGCGCCGGCCAGCCCGGCCAACAGCGTGAACAAGTGCCCGGTGTGCGGCGTGGTCAGCCCCACCGCGGCGCTTGCCCGCAAGCACATGGAGATGCACGGGACGGTCAAGGCGTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGCGCACCCACATCCGCACCCACTTCGACAAGAAGACCAGCGACGTGAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGacgcggctgcggcagcagcccCGCCACCACCCACCATGGGCCTCGACCTGCCCGCCGTGGCAGCCGCccaggagcagctggagcagcatgCGGCGCAGATCTTCAACTGCGACCACTGCAACTACGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAACTGTTGCATCCACATGTGGCTATCAGCTCGCCCTCCATATCTCCCGAGTCCCGTGAACAGGATACCAATGCCCATGCCCTGCCCGAGGTGGCGCTGGTAAACGGCGAGCGCGAGGCGGCCAGTTTCCACATCAAGTCGGAGCCCTTGGACCCACCGGTGGCCACGTTGGGTCTGGTGCATGAGAACAACAATTCGCCCATCGGCACGCCGCATACCCACATCAAAGCCGAGCCGCTGGACATGGGCATAGAGCTAACCGCAGCCACACTGCCACCGCCCATGGCCAATTCGCCGCTGGGGCCGAGCGCCGCGGAGGCCATGAAGAAGTACTGTTCCACCTGCGACATCTCGTTCAACTATGTGAAGACCTTTTTGGCCCACAAACAGTTCTACTGCAAGAGCAAGCTGCACCGGCCGGAGGCCAGTGACAGCCCCAGTCCCACTGTGGGCGTTGGTGGCGCCGCCATGCCGCTGCAGTCGCCCagcgagctgttgctgctgcagaagAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MQLLKDSKDLGAHELSEEKQQQQLEEQPEDEQLEQHASSASEQLEETDMDQELAEEEPVAASAQQQNAADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLEPRLLGPPPQLAKPEQQQQQQQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEDSAGGDKAAAGAGGGSNATASSGSSGGSSGSEPPAKMARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVVAAAAAAAAAVNALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEASANSNSAGPAVGGSAAAAAAAGVKLSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALSINALTGNATPTPTPMPSSSQLSMPALEPERHSAGSLLETEAKSSPPEPKRKEASGMRETTPLDLSLRRSPISPLLQRQRLMEEALLSAGKENMESSARTGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSAASMSPPALAVPHLLDNLQPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSSAELASKLGFSPQTGAAPPPAVANVAANAPSSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTGADGDSKHAVTPPAAAGPGAVAGASSLETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHEHGQPCPTPPATPQLAPASPANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAAAAPPPPTMGLDLPAVAAAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDTNAHALPEVALVNGEREAASFHIKSEPLDPPVATLGLVHENNNSPIGTPHTHIKAEPLDMGIELTAATLPPPMANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPTVGVGGAAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -