Basic Information

Gene Symbol
RREB1
Assembly
GCA_035047545.1
Location
JAWNPL010000146.1:1060628-1067174[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0057 0.39 11.3 0.6 1 21 251 271 251 273 0.96
2 13 0.00033 0.022 15.2 0.2 1 23 283 305 283 305 0.98
3 13 7.9e-05 0.0053 17.2 7.3 1 23 311 333 311 333 0.98
4 13 0.14 9.6 6.9 0.9 2 20 541 559 541 561 0.93
5 13 0.04 2.7 8.7 0.0 1 23 716 738 716 738 0.97
6 13 1.2e-05 0.00081 19.7 0.7 1 23 748 770 748 770 0.99
7 13 0.00081 0.055 14.0 2.0 1 23 776 799 776 799 0.97
8 13 0.0029 0.2 12.2 2.0 1 23 1046 1069 1046 1069 0.95
9 13 8.4e-05 0.0057 17.1 0.3 2 23 1400 1421 1399 1421 0.97
10 13 0.14 9.5 6.9 6.3 1 23 1427 1450 1427 1450 0.97
11 13 3.1 2.1e+02 2.7 4.2 1 23 1572 1595 1572 1595 0.88
12 13 0.0082 0.55 10.8 0.5 3 23 1647 1667 1645 1667 0.96
13 13 0.0013 0.088 13.3 4.8 1 23 1673 1695 1673 1695 0.99

Sequence Information

Coding Sequence
atgctggccacacagcagcagcagcagcagcagcagcagccgccgcaacagcaacatacagcagcaacagctgccgctgcagctgcagctgtcgcgGGAGTAACTCTTGAGGATGCGGTCATGGAGCGTCAGCGGCGCGACTCCAGCACCTCGGAGTCCTCGCTGGAGCATCTGGATCTGGGCCGCACGCCAAagaagctgagcagcagcagcggcgcgcCGCAGCCGACGTCGACGCCGCACGTGGAGGCGACGTCGCGGAAGCGCAAgctgcgacagcagcaacagcagcagcagcagccagccctCTACTCCGACGAGgaggaagagcagcagcagcagcagcagcagcagcagcatcaacagcatcagcaacagttgctggaGCAGTCGGTGCATCGCATGCGGCACAAGCAGCGGCGCAGCGGCAAtgcagtcgctgccgctgccagcgcGAGCATCGTCGTCGACTACAGCGtcggcagcgacgccagctcGCTGCGCAAAAAGTTCCGGCTGaaccgcagcagcatcagcgccCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGACGGCAGCGCCCACAGCGGCTACTTGctcagcgccagcagcgcgcCGCAGCCGGCGacggcagcgcagcagcagcagcagcctggcTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAGGGCCTGTGCCACTCGAGCGCCGAGTCGGGCATCGGCGCCGGCGACGAGCACATGAAGTACGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATCCGATGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTACTCTCGTCGGCCTCCTCGCTGGACAGGCACGTCCTGGTGCACACCGGGGAGCGTCCCTTCAACTGTCGCTATTGCCACCTGACGTTCACGACGAACGGCAACATGCACCGGCACatgcgcacacacaagcaacaccagcagcagcagcagcagcagcaaccacagcaaccacagcaacagcaacagcagcaacagcaacagcaagttcagtcacagcagcaacagttgcagcgacgccagcaacATGCCAATGCCAGTGCTGGGGCGCAGCGCGCCGAGAGCTATGAGAGCGACGCCAGCTGCTCCACGGAcatctccagcagcagcagcagtgcagccagcaacaacaacaacaacaacaacaacaacagcagcagccaagcgaacaacaacaacaacaacagtcaggaggagcagcaactgttgctggcgtgcaagcagcagcagctgaagaccaacatcaacaacaacaacatcatcgtGAGCGACGAGCGAGCACTGGACACGGatggcgagggcgagggcgatgGGGACGAGGCGGAGAGCGTCGATGTCACCCAGATGATAACGAGCACGCCGGATGTGGCCACGCTGCTGGCGACGTCGTCGGGCGGCAGCAGCCCGCGCAGCCCGCGCAGCCCGGAGGCCGCACAGCTGGCCAGCTGCCCAGCGTGCAGTGCGGATGGGTTCGAGACGCTCGCCGCGCTCTACGCCCATCTGGAGGCGGAGCACGGCGACATACCCGCCAAGTGCCGGGAGTGCGAGGTGATCTTCGGTACGCAGCGTCAGCTGCAGGCGCACAGCTGTCGcgggctgcagctgccgccgctgctgggcGCCAGCTCCTCGCCGCTGCACAAGCAGGAGCCGCCGGAGGAGCACGAGCAGGACCAAGAGCAGCGGGCGCAGGAGCAggatgaggaggaggcggaggaggcggaggcggaggcggaggaggaCGCACTGCGTCTGCAGGCGAACAGCGAACGGGACGAGTTCTTCCAGCAGCTGTATCTGAAGGGCAAGTCGGACGGCTGCTCGCTGCCGTCGCCCATCAAGCACGAGCCGGCGGAGCAGCGCCAGGATCTGGCGGACATCCAGAGCATACTGCAGAtgaccagctccagctgcacctCCAGCTTCCTGCGCAACTTCGAGCAGAGCGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGGCGCGACGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTCCGCGGCGAGTTCCCCTGCAAGCTCTGCGCCGCCGTCTTTCCGAACCTGCGCGCCCTCAAGGGCCACAATCGGGTGCACCTGGCCAGCGTCGGGGCCGCCGGGCCGTTCCGGTGCAACATGTGCCCGTACGCCGTGTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTATGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGCAAGACCAGCCGGGACGAGGTGAAGCGCGCCATCGTCTACCATCCGGCGGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGCTCGACCCGGATCTGTCCGAGCTGAGCTTCCGTTCGCTCAGTCCGGCGCCCTCCGTCGAGGCCAGCTCCCAGCTGAAGCACATGTTGCTATCGGAGCAGCCCGCCAAGCAACAGTTGCcgacccagcagcagcagcagcaacagttgccggcGCAGCCTGCGCTGAAGATTCAGGTGAAGAGCCTGGATCAGCTGGTGGAGAAGCCCCAAGCGCCGGCCATGGATCTCAGCATGGACGTGCTGGACCTCAGCAAGAAGCCGCAGCGCGAGCAcgagctgctcctccagcagcaacaacagcagcagcagcagcagcaacagcagcagcaacagttgctcttCAGTCCGGGCGATGCGGCCACGCAGTACATGCAGCTGCTCCGTAGCCTGATGCTGCAGCAGTCCTCCGGCTTTCCGTTCTTCGGGCTGATGGCGCCGCCGCCCGCGGAGAAGTCGACGCCGGCCATGGCCGTGCCGACgtcagcgacggcgacggcaacggcggcgggagcaacagttgccgccgtgccgctgccgctgccgctgggcGGCCTGGGCGTGCCAGTGCCAGCCGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATgccgaagcagaagcagcgacGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCGGCCCGCTTCACCCTCCGCTCGAACATGGAGCGGCACgtgaagcagcagcatcccCAGTTCTACGCCCAGCGGCAGCGCAGCGGGCACCACGTGATGCGCGGCCGAGCGGCCAACTCGGGCGCCgcccaggcagcagcagccgcagcagcagcagccgccgccgccgccgccgcagccatGAGCAATctgcaccagcaacagcaacaccagcagcagcagcagcagcaacagcagcaacatgcgcCCATCTCGGAGCAGGTGAAGTACGCGAtcctggcgcagcagctgaaggcGCGCAAGGACACGGACTtgctgcagcaggcgctggCGCACGGCTCCAGCAGCGTCGTCGTGAATCCTCTGCTGCACTTTAACTACAACAGCAAtgccaacggcagcagcagcagcaacagcaacagcaatcaacagaagcagcagcagcagcaacagttgcccgTGGATGACGATGAGCCGCCGAAGCTGATCATAGACGAGGACGATGAGGATGAGTTCGATGACAtagacgaggaggaggaggagcaggaggaggaggaggaggaggaggaggaagaagaggaGCACCTCGAGCCAGACGAGccacagctggagcagcagcagaaggagcaactgcagccagcGGTGCCCGAGCCACTGGCTGAGCCCTTGGCCCTGcccgtggccgtggccgtggccgaTCCTCCGGCAGCTGAGCCAACCAGCATGAAGAGCATGATTGCCCAGGCGGAGTCGGTGGGCAAGTCCCTCAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCGAAGCTGGTGGACAACGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagccCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGGGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTGACGCATACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGGCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCCATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTCGAGGAGCAGCGCCGCCGCAAGGCCGCCGAACAGGAGCGccagctcgagctggagcGCGAACGGGAGCACGAGCGTCAGCTGGAACGGGAGCGCGAACTGGAGCGGgagcgcaagcagcagcagctcatccaGCAGCTGACGGCGGCGGCCCAGCTCAGCCAGCAGATggtggccgccgccgccgcccaggCCGCCcaggccgccgccgccgccgcccaggCAACAGCCGTCCAGGCATCAGGGAGCGAGGCGAACGGCAGCGAGCTGCCGTACAAGTGCCACCTGTGCGAGTATTCGTTCGGGGAGCGGATGCAGTGCCTCGACCACATCAAGCAGCAGCACGCGCAGGAGTTTGCGCTGCTCCTGGCCAAGGGCGCCATCGAAACGGAGCAGGAGACGGCACCGAGCTCCGCCGCCGTCGTTGTGTCCGAGGACGAGTCGAGTGCCGGACGGAGCGGCGGTAAGTATCCGGACTACAGCAACCGGAAGGTGATCTGCGCGTTCTGCGTGCGCCGCTTCTGGTCGACGGAGGACCTGCGCCGGCACATGCGCACCCACTCGGGCGAGCGGCCCTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGCGGGCGCAGCCACAACGGCGAGCCGGGCGCCTCTGACTGCTCCGATGATGAGCAGatggccacgcccccaacgACACCGACGCCCACGGCTGTAGCCATGCCCATGCCAgtgcccagcaacaacaacaacaacaacaacaacacttgccacaacaacaacaacacaaacagcaacaacaacaacaacaacaacaagagcctGCGACTGCCCAAGCTCCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTGAGCCGCCTCGGCGAGCACAAGGAGAACATTGCCGAATCCTCAACGCCCACTACGGCAGCGGCCGTAGGCGtaggcgtgggcgtgggcgtggccagcggCGATTTCCTCGGCAACCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCGGACGAGGCGGCCAAGCTCCTGGGCGTCGAGAAGTGA
Protein Sequence
MLATQQQQQQQQQPPQQQHTAATAAAAAAAVAGVTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHVEATSRKRKLRQQQQQQQQPALYSDEEEEQQQQQQQQQHQQHQQQLLEQSVHRMRHKQRRSGNAVAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASSAPQPATAAQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQQQPQQPQQQQQQQQQQQVQSQQQQLQRRQQHANASAGAQRAESYESDASCSTDISSSSSSAASNNNNNNNNNSSSQANNNNNNSQEEQQLLLACKQQQLKTNINNNNIIVSDERALDTDGEGEGDGDEAESVDVTQMITSTPDVATLLATSSGGSSPRSPRSPEAAQLASCPACSADGFETLAALYAHLEAEHGDIPAKCRECEVIFGTQRQLQAHSCRGLQLPPLLGASSSPLHKQEPPEEHEQDQEQRAQEQDEEEAEEAEAEAEEDALRLQANSERDEFFQQLYLKGKSDGCSLPSPIKHEPAEQRQDLADIQSILQMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLASVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKLDPDLSELSFRSLSPAPSVEASSQLKHMLLSEQPAKQQLPTQQQQQQQLPAQPALKIQVKSLDQLVEKPQAPAMDLSMDVLDLSKKPQREHELLLQQQQQQQQQQQQQQQQLLFSPGDAATQYMQLLRSLMLQQSSGFPFFGLMAPPPAEKSTPAMAVPTSATATATAAGATVAAVPLPLPLGGLGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAMSNLHQQQQHQQQQQQQQQQHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVVNPLLHFNYNSNANGSSSSNSNSNQQKQQQQQQLPVDDDEPPKLIIDEDDEDEFDDIDEEEEEQEEEEEEEEEEEEHLEPDEPQLEQQQKEQLQPAVPEPLAEPLALPVAVAVADPPAAEPTSMKSMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELEREREHERQLERERELERERKQQQLIQQLTAAAQLSQQMVAAAAAQAAQAAAAAAQATAVQASGSEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQETAPSSAAVVVSEDESSAGRSGGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEPGASDCSDDEQMATPPTTPTPTAVAMPMPVPSNNNNNNNNTCHNNNNTNSNNNNNNNKSLRLPKLHELLDKANEWRVSRLGEHKENIAESSTPTTAAAVGVGVGVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512904;
90% Identity
-
80% Identity
-