Basic Information

Insect: Drosophila paramelanica
Gene Symbol: RREB1
Assembly: GCA_035043915.1
Location: JAWNMO010000557.1:2042298-2048446[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.034 2.1 8.9 0.8 1 21 228 248 228 250 0.93

2 12 0.00032 0.019 15.3 0.2 1 23 260 282 260 282 0.98

3 12 9.9e-06 0.00061 20.0 3.9 1 23 288 310 288 310 0.98

4 12 0.17 11 6.7 1.6 2 20 489 507 489 509 0.93

5 12 0.0079 0.49 10.9 0.1 1 23 644 666 644 666 0.97

6 12 3.5e-05 0.0022 18.3 1.4 1 23 676 698 676 698 0.99

7 12 0.00078 0.048 14.0 2.0 1 23 704 727 704 727 0.97

8 12 0.0029 0.18 12.3 2.1 1 23 1004 1027 1004 1027 0.95

9 12 8.1e-05 0.005 17.1 0.3 2 23 1354 1375 1353 1375 0.97

10 12 0.14 8.4 7.0 6.3 1 23 1381 1404 1381 1404 0.97

11 12 0.0079 0.49 10.9 0.5 3 23 1603 1623 1601 1623 0.96

12 12 0.0013 0.078 13.4 4.8 1 23 1629 1651 1629 1651 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.034	2.1	8.9	0.8	1	21	228	248	228	250	0.93
2	12	0.00032	0.019	15.3	0.2	1	23	260	282	260	282	0.98
3	12	9.9e-06	0.00061	20.0	3.9	1	23	288	310	288	310	0.98
4	12	0.17	11	6.7	1.6	2	20	489	507	489	509	0.93
5	12	0.0079	0.49	10.9	0.1	1	23	644	666	644	666	0.97
6	12	3.5e-05	0.0022	18.3	1.4	1	23	676	698	676	698	0.99
7	12	0.00078	0.048	14.0	2.0	1	23	704	727	704	727	0.97
8	12	0.0029	0.18	12.3	2.1	1	23	1004	1027	1004	1027	0.95
9	12	8.1e-05	0.005	17.1	0.3	2	23	1354	1375	1353	1375	0.97
10	12	0.14	8.4	7.0	6.3	1	23	1381	1404	1381	1404	0.97
11	12	0.0079	0.49	10.9	0.5	3	23	1603	1623	1601	1623	0.96
12	12	0.0013	0.078	13.4	4.8	1	23	1629	1651	1629	1651	0.99

Sequence Information

Coding Sequence: atgctggccacacagcagcagcaacaactcacggcaactgcaacaacaacagcagcagcagcagcagcagctgcaacaacaacagcagcaacaacaacagcagcaacagtagcactTGAGGATGCGGTTATGGAGCGACAGCGTCGCGATTCGAGCACCTCGGAGTCCTCGCTGGAGCATCTCGACTTGGGCCGCACACCAAAGAAGCTCTGCAGCGTTGGCGGCGCGCCGCAGCCGACGTCTACCCCGCACGAGGCAACGTCGCGCAAGCGCAAgctccgccagcagcagcaacaacaacagcaacaacatttgctgTCCGACGAGGAGgaagagcagctgcagctgcagcgactgCGCGACAGGCAGCGACGCAGcgccgctgccagcgccaGCATCGTGGTCGATTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAACCGCAGCGCGACGAACGGAGAGCTGGGCGAGTCCGGTTTTGTCGATGGCAGCGCCAACAGCGTTTTTCTGcagagcagcgccagcagcggcagcgctgcGCAGGCATCAACGACGGCGCCGCCGCTGgcgtcgagcagcagcagctccggcGGCTCCTCGCCGCAGGATCTGTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATACCTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGATGCCACAACTACGCCAACGGCGACACCGAAAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCCTCCTCGCTGGACAGACACGTGCTGGTTCACACCGGCGAGCGTCCGTTCAACTGCCGTTACTGTCCGCTGACGTTCACCACCAACGGCAACATGCACCGTCACATGCGCACCCACAaggagcaccagcagcagcagcagcagcagcaacattcccagcagcagcagcaacagtcgcagcagcagcagcaacattcacAGCAGCACGCAGCGACcggcagcagcagcagccacaacaacaacaacaacaacaacaacaataataataatagtcaaaagacaaacaacaacaatgtggaggaagaggaagacgaacggcaactgttgcaggCGTGCAAGCGACGTCGCCACAAaaccaacatcaacaacaacaacatcattttGAGCGACGAACGCGAACTGGACTCGGAGCAGGAACCGGAACAGGATCACGATGACGATCACGATCACGATGACGATCACGATAACGATCAGAATATGGCGCAGATGATCACCAGCACACCGGACGTGGACACGCTGCTGGCCTCCGGCGGCAGTTcgccggcgccgccgccaTCGCTGGCCAATTGTCCGGCGTGCGATTCCGGCGAATTTGAGACGCTGGCGGCGCTGTGGGCGCACCTGGATGAGCAGCACGCGGATATTCCGGCCAAGTGTCGCGACTGCGATGTCATCTATGCGACGCACCGCCAGCTGCAGGCGCACAGCTGCCGGGGGGCGGGGCTGCCGCCTCTGATCGGACAGAGCAGCTCGCCGCTGCACAAACAGGAGCTGCCCGATGAACTGGATGCGGACGAGGAGCAGCATAACGATCGGGAGCTGAACAGCGAGGAGCGCGACGAGTTCTTTCAGCAGCTGTATCTGAAGGGCAAATCCGGCGGACAGCTGCCGTCGCCGATCAAACACGAACCGTCCGATCAGCGCCAGGATCTGGCCGATATACAGAGCATATTGCAGATGACCAGCTCCAGTTGTACGTCCAGTTTTCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCTTGGACGGGCGCGATGGGGAGGAGGAGGCGCAGGATGCGTTCACCAGCGAATTCCGCCGGATGAAATTGCGCGGCGAATTCCCCTGCAAATTGTGCACAGCGGTTTTCCCCAATCTGCGCGCCCTGAAAGGACACAATCGCGTCCATTTGGCGGCCGTCGGTCCGGCGGGTCCGTTCCGTTGCAACATGTGCACGTATGCGGTGTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGGGATCGTCCGTACGAGTGCGCCGTCTGCAATTACGCGTTCACCACGAAGGCCAACTGTGAGCGCCACCTGCGGAATCGCCATGGGAAGACGAGTCGCGAGGAGGTGAAGCGGGCGATTGTCTATCATCCGGCGGAGGATGCCAGCTGCGAGGAGCCGGCaacaggcagcaacagcagcagcagcagcaaaccaacagcagcagcaaccaatcAACTGGATCTGAACGATCTCAGCTATCGTTCGTtgacaccgccgccgccgccgcctgcgCCGCCGCTCGAGCTGAGCAGCTCGTCGCAGCTGAAGCACATGCTGCTGGCGGAGGCGATGCCGGCGAAGACACCGCTCAAAATCCAGGTGAAGAGCCTCGACCAGCTGGTGGAGAAGCCAATTGAGCAGCTGCACGAGAAGCCCGCCATCGATCTGAGCATGGATGTGCTCGATCTGAGCAAGAAGCCGGCGGCGACAACGCTGGAGCTGCTCGAACGGGAGCGTGAAAAGGAGCGGGAGAGGGAGCGCGAGAGGGAGCAtgaattgctgctgcagcaacagcaacagcagcaacagcagcagcagcaacagcagcaactatttGGTGATCCCGCGACGCAATATGTGCAACAGCTGCTCCGGAATCTGATGTTCCAGCAGAGTTCCGGTTTTCCGTTCTTCGGTTTTATGGCGCCGCCAGCAAATCTGGACAAATccttggcagcagcagcagcagcaacagcaacacaaacagcggcagcagcagcagcagcagtgcccGCTGTTGCCGCGCCCGTTGCAGCGGTGCCGCCCGCCTTGGGACTGCCGCTGGCGGCGGGCGGACCCGTCAAGATGGTGATCAAGAACGGCGTCCTGATGCCCAAACAGAAGCAGCGGCGCTATCGCACCGAGCGACCCTTCGCCTGCGAGCACTGCACCGCCCGGTTCACGCTGCGCTCCAACATGGAGCGGCACGTCAAGCAACAGCATCCGCAGCACTATGCGCAGCGCCAGCGCAGCGGCCATCACGTCCTGCGCGGCAGGGCGGCCAATTCGggagcggcggcagcagcggccgcggccgcggcagcagcagcagccgccgcagcagcagcagcgatgagCCAGCAACATGTTCATCCGCATTCGCATCCGCATTCGCATCCGCATGCGCATGCGCTGGCGCCGCATCCGGCGCCCATTTCGGATCATGTGAAGTACGCGATCCTGGCACAGCAGCTGAAGGCGCGCAAGGACACGgatctgctgcagcaggcgctggcgcacggcagcagcagcattgccGGGCATCCGCTGCTCCAAGCGAACTACACGAaaagtgcgagcaacaacCTGGACGATGATGAGCCGCCCAAGTTGATCATTGACGAAGATGAGGAGGAGGATTTCGATGATGGCGAGGAGgaggatgacgacgacgacgaggaggaggagttgctcgaacaggagcaggagcaagAGTTGCCATcagaaaagcagcaacagctgacgGAGCAACTGCCTCCGGAGTCGGTCAACAAAAAAGTGGAGCAACCGGAAACGGAGCAAAAAgtaattgccacgcccaccaccacaagcagcagcagcgtaacGCCCACTGTGGTGCAGGCGAGCACAATGAAGAGCATGATTGCCCAAGCGGATTCGGTGGCGAAATCATTGAAAGAGGTGGCCAGTTCACCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAACGCGACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCGAGCGACGTGGCCAATCACATGGAACAGAGCGACGAGGAGGGACTGGTGGCCTCCGGCAGCGCCagcgagagcaacaacagcggcaccGAGGAcgtcaccagcagcagcagcagcagctgctgcaacgaACCGAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGGGTCAGCTGTCCGTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTGCGCCGCCACATTTTGACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGGCATCTGTTGCGGAAGCACGGCAACGTGGAGTCCGCGATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCAGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGACGCCGGCAGGCGGCGGAACTGGAACGGGAGCGGGAACGCGAACGCGAGCGAGAATTGGAGAGGGAGCGGGAACGGGAGCGTGAGCGCGAAAAGGAACTGGAACgtgaacgggaacgggaacgagaTCTCATCCAGCAGCTGACGGCGGCGGCACAGCTCGGCCAGCAAATGGCCGccgcggtggcggtggcggcagccGCGAACGCCGGCGAACCGGAATCGAACGGCAGCGAGCTGCCGTTCAAGTGTCACCTGTGCGAGTTCTCGTTCGGAGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGAGCACGAGTTCgccctgctgctggccaaaggAGCCATCGAaacggagcagcagcagcagcagcaaccgcagcagcaatcgACACCAGCTGCGGTCCACTCCGAGGATGAGTCCAGTGCCGGGCCGGGTGCAGCGCGTGCCGGCAAATATCCGGATTATAGCAACCGCAAGGTGATCTGTGCGTTCTGCGTGCGCCGCTTCTGGTCGACGGAGGATCTGCGCCGGCATATGCGCACCCATTCCGGCGAACGGCCGTTCCAGTGCGAGATCTGCCTGAGGAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGCCACAACGGGGAGCAGGGCGGCTCCGATTGTTCCGACGATGAGCAGCTGGCGACGCCGCCCACAACGCCAGCGCCAACGCCGctacccaacaacaacaacaacaataatacttgccacaacaacaacaataacaacaacaacaacaacaaacgactGCCGAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTGAGTCGCCTGGGCGAGCACAAGGAGAACATCGCCGAGGCGACAACTGCGACGCCCGCCGCTGCCAGCGGCGATCTGATTGGCAACCTGCTCGGGATCAGCGATCAGGGCATACTAAACAAGCTGCTCTCCTCCGCGGACGAGGCCGCCAAGCTTCTGGGCGTGGACAAGTAA
Protein Sequence: MLATQQQQQLTATATTTAAAAAAAATTTAATTTAATVALEDAVMERQRRDSSTSESSLEHLDLGRTPKKLCSVGGAPQPTSTPHEATSRKRKLRQQQQQQQQQHLLSDEEEEQLQLQRLRDRQRRSAAASASIVVDYSASGDASSLRKKFRLNRSATNGELGESGFVDGSANSVFLQSSASSGSAAQASTTAPPLASSSSSSGGSSPQDLCHSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCPLTFTTNGNMHRHMRTHKEHQQQQQQQQHSQQQQQQSQQQQQHSQQHAATGSSSSHNNNNNNNNNNNNSQKTNNNNVEEEEDERQLLQACKRRRHKTNINNNNIILSDERELDSEQEPEQDHDDDHDHDDDHDNDQNMAQMITSTPDVDTLLASGGSSPAPPPSLANCPACDSGEFETLAALWAHLDEQHADIPAKCRDCDVIYATHRQLQAHSCRGAGLPPLIGQSSSPLHKQELPDELDADEEQHNDRELNSEERDEFFQQLYLKGKSGGQLPSPIKHEPSDQRQDLADIQSILQMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCTYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEEPATGSNSSSSSKPTAAATNQLDLNDLSYRSLTPPPPPPAPPLELSSSSQLKHMLLAEAMPAKTPLKIQVKSLDQLVEKPIEQLHEKPAIDLSMDVLDLSKKPAATTLELLEREREKEREREREREHELLLQQQQQQQQQQQQQQQLFGDPATQYVQQLLRNLMFQQSSGFPFFGFMAPPANLDKSLAAAAAATATQTAAAAAAAVPAVAAPVAAVPPALGLPLAAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCTARFTLRSNMERHVKQQHPQHYAQRQRSGHHVLRGRAANSGAAAAAAAAAAAAAAAAAAAAMSQQHVHPHSHPHSHPHAHALAPHPAPISDHVKYAILAQQLKARKDTDLLQQALAHGSSSIAGHPLLQANYTKSASNNLDDDEPPKLIIDEDEEEDFDDGEEEDDDDDEEEELLEQEQEQELPSEKQQQLTEQLPPESVNKKVEQPETEQKVIATPTTTSSSSVTPTVVQASTMKSMIAQADSVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSCCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAELERERERERERELEREREREREREKELERERERERDLIQQLTAAAQLGQQMAAAVAVAAAANAGEPESNGSELPFKCHLCEFSFGERLQCLEHIKQLHEHEFALLLAKGAIETEQQQQQQPQQQSTPAAVHSEDESSAGPGAARAGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGGSDCSDDEQLATPPTTPAPTPLPNNNNNNNTCHNNNNNNNNNNKRLPKLHELLDKANEWRVSRLGEHKENIAEATTATPAAASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547526; iTF_00541976; iTF_00561209;
90% Identity: iTF_00561209;
80% Identity: -