Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: RREB1
Assembly: GCA_004149445.1
Location: SCDR01000538.1:65504-72096[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.029 3.5 8.8 0.8 1 21 282 302 282 304 0.93

2 13 0.00027 0.033 15.2 0.2 1 23 314 336 314 336 0.98

3 13 8.5e-06 0.001 19.9 3.9 1 23 342 364 342 364 0.98

4 13 0.15 18 6.6 1.6 2 20 569 587 569 589 0.93

5 13 0.0072 0.86 10.7 0.1 1 23 725 747 725 747 0.97

6 13 3e-05 0.0036 18.2 1.4 1 23 757 779 757 779 0.99

7 13 0.00067 0.081 14.0 2.0 1 23 785 808 785 808 0.97

8 13 0.0025 0.3 12.2 2.1 1 23 1081 1104 1081 1104 0.95

9 13 7e-05 0.0084 17.1 0.3 2 23 1430 1451 1429 1451 0.97

10 13 0.12 14 6.9 6.3 1 23 1457 1480 1457 1480 0.97

11 13 7.7 9.2e+02 1.2 4.0 1 23 1594 1617 1594 1617 0.87

12 13 0.0069 0.82 10.8 0.5 3 23 1677 1697 1675 1697 0.96

13 13 0.0011 0.13 13.3 4.8 1 23 1703 1725 1703 1725 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.029	3.5	8.8	0.8	1	21	282	302	282	304	0.93
2	13	0.00027	0.033	15.2	0.2	1	23	314	336	314	336	0.98
3	13	8.5e-06	0.001	19.9	3.9	1	23	342	364	342	364	0.98
4	13	0.15	18	6.6	1.6	2	20	569	587	569	589	0.93
5	13	0.0072	0.86	10.7	0.1	1	23	725	747	725	747	0.97
6	13	3e-05	0.0036	18.2	1.4	1	23	757	779	757	779	0.99
7	13	0.00067	0.081	14.0	2.0	1	23	785	808	785	808	0.97
8	13	0.0025	0.3	12.2	2.1	1	23	1081	1104	1081	1104	0.95
9	13	7e-05	0.0084	17.1	0.3	2	23	1430	1451	1429	1451	0.97
10	13	0.12	14	6.9	6.3	1	23	1457	1480	1457	1480	0.97
11	13	7.7	9.2e+02	1.2	4.0	1	23	1594	1617	1594	1617	0.87
12	13	0.0069	0.82	10.8	0.5	3	23	1677	1697	1675	1697	0.96
13	13	0.0011	0.13	13.3	4.8	1	23	1703	1725	1703	1725	0.99

Sequence Information

Coding Sequence: ATGTTCATGTTAAGTTTAAGTAATTATTCTCTTAATGCTCATGTTAATCCTAATGCTAAGCACAGCAGACAAGCAGCAGCCGTTTACGATCTCAATTAGCCAACTTtcacaacgacagcagcagcaaaaatgctggccacacagcagcagcaacaactcacggcaactgcagcagcagcaacaacaacagcagcagcagcaacagcagcaacagcagcagcagcaacagcagcaacaacaacagcagcaacagtagcacTTGAGGGTGCGGTTATGGAGCGACAACGTCGCGATTCGAGCACCTCGGAGTCCTCGCTGGAGCATCTCGACCTGGGCCGCACACCAAAGAAACTCTGCAGCGTTGGCGGCGCGCCGCAGCCGACGTCAACGCCGCACGAGGCGACGTCGCGCAAGCGCAAGctccgccagcaacagcagcagcagcaacagcaacatttgctgTCCGACGAGGAGgaagagcagctgcagctgcagcgactgCGCGACAAGCAGCGACGCAGcgccgctgccagcgccagcaTCGTCGTCGACTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGCAAGAAATTCCGACTGAACCGCAGCGCGACCAACGGGGAACTCGGCGAATCGGGTTTTGTCGatggcagcgccagcagcgcttTTCTGCAGAgcagcgtcggcggcggcagcggcggcggcagcgctgtCCAGGCGTCAGCGACtgcgccgctgctggcgtcgagcagcagcagcagctcctctgGCGGCTCCTCGCCGCAGGATCTGTGCCATTCGAGCGCCGAATCGGGCATCGGCGCAGGGGACGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCCGATGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCCTCCTCGCTGGACAGACACGTGCTGGTTCACACGGGCGAGCGTCCGTTCAACTGTCGCTACTGTCCGCTGACGTTCACCACGAATGGGAACATGCATCGTCACATGCGCACCCACAAggagcaccagcaacagcagcagcagcattcacagcagcagcaacagtcgcagcagcattcgcagcagcaacattcacagcagcaacactcgcagcagcagcagcgacgtcagcaGGTTCAGGGCGCCAGCTACGAGAGCGACGCCAGCTGCTCGACGGACGTttcaagcggcagcagcagcagtcacaacaacaacaacaacaacaacaataacaacaatagtcagaaaacgaacaacaacaacaatgtggaggaagaggaagacgaacggcaactgttgcagGCGTGCAAGCGACGTCGCCACAAgaccaacatcaacaacaacaacatcattttAAGCGACGAGCGCGAACTGGACtcggagcaggagcaggagcaggaaccGGAGCACGAACAGGATCAAGATCTGGATCAGGATCAGGATCAGGATATGGCGCAGCTGATCACAAGCACACCGGACGTGGACACATTGCTGGCTTCGGGCGGCAGTTCACCGGCGCCGGCGTCGCCGCCATCGCTCGTAAATTGTCCGGCGTGCGATTCCGGCGAATTTGAGACGCTGGCGGCGCTGTGGCAGCACCTGGACGAGCAGCACGCGGACATTCCGGCCAAGTGTCGCGACTGCGATGTGATCTATGCGACGCACCGCCAGCTGCAGGCGCACAGCTGCCGGGGGGCGGGGCTGCCGCCTCTGATCGGAACGAGCAGCTCGCCGCTGCACAAACAGGAGCTGCCCGACGAGCTCGATGCGGACGAGGAGCCAGAAGCCAACGAACGGGAGCTGAACAGCGAGGAGCGCGACGAGTTCTTTCAGCAGCTGTATCTGAAGGGCAAATCCGGCGGACAGCTGCCGTCGCCGATCAAACACGAACCGTCCGATCATCGCCAGGATCTGGCCGACATACAGAGCATCCTCCAAATGACCAGCTCCAGTTGCACGTCCAGTTTCCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGCCGGGACGGGGAGGAGGAGGCGCAGGATGCGTTCACCAGCGAATTCCGCCGGATGAAATTACGCGGCGAATTTCCCTGTAAATTGTGCTCAGCCGTGTTCCCCAATTTGCGGGCGCTGAAGGGTCACAATCGTGTCCATTTGGCGGCCGTGGGTCCGGCCGGACCCTTCAGGTGCAACATGTGCACCTACGCCGTGTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGATCGTCCCTACGAATGCGCCGTCTGCAATTACGCGTTCACCACGAAGGCGAACTGTGAGCGGCACTTGCGGAACCGGCACGGGAAAACGAGTCGCGAGGAGGTGAAACGGGCGATTGTCTATCATCCGGCGGAGGATGCCAGCTGCGAggagccagcagcaacagcagcagcaacaaccacgaACAGCAaacccacaacaacagcagcagcagcaaccaaccAACTGGATCTGAACGATCTGAGCTATCGATCgctgacgccgccgccgccgcctccggcTGCTCTGGAGCTGAGCAGCTCATCGCAGCTGAAGCACATGTTGCTGGCGGAGGCGCTGCCCGCGAAGACACCACTGAAGATACAGGTGAAGAGCCTCGATCAGCTGGTGGAGAAGCCAGTCGAGCAGCTGACCGAGAAATCGGTGATCGATCTGAGCATGGATGTGCTCGACCTGAGCAAGAAgccggcgacgacgacgctggTCGAAAGGGAGCGCGAAAGGGAACGGGAAAGAGAACGCGAAAGGGAACACGAGTTGCtgatgcaacagcagcagcagcagcagcaacagcagcagcaacagcaactgtttgGTGATCCAGCCACGCAATatatgcagcagctgctccggAATCTGATGTTCCAGCAGAGTTCCGGTTTTCCGTTCTTTGGTTTTATGGCGCCGCCAGCGAATTTAGAAAAgtctttggcagcagcagcagcagcaacagcaacacaaacgGCAGCAGCCGCGCCCGTTGTTGCCGCGCCCGTCGCGGCGGTGCCGCCTCCGTTGGGACTGCCGCTGGCCGCGGGCGGACCCGTCAAGATGGTCATCAAAAACGGCGTCCTGATGCCCAAACAGAAGCAGCGCCGCTATCGCACCGAGCGACCCTTCGCCTGCGAGCATTGCACGGCGCGGTTCACGCTGCGCTCGAACATGGAGCGGCACgtgaagcagcagcatccgcaACACTatgcgcagcgccagcgcagCGGCCATCACGTCCTGCGCGGCAGAGCGGCCAATTCgggagcggcagcggcggcggcggcagcagcggcagcggcagcagcagccgcagcagcagcagcgatgagCCAGCAACATGTTCATCCACATCCGCATTCGCATCCGCATTCGCATGCATTGGCGCCGCATCCGGCGCCCATTTCGGACCACGTGAAGTACGCGATcctggcgcagcagctgaaggCGCGCAAGGACACggatctgctgcagcaggcgctggcgcaCGGTTCCAGCAGCATTGCGACGCATCCGCTGCTCCAGGCGAACTACACGAaaagcgccagcaacaacctGGATGATGATGAGCCGCCAAAGTTGATCATTGACGAGGATGACGAGGAGGATTTCGATGAGGTGGAGGAGGAtgacgacgaggaggaggaggaggaggagttgctggagcaggagcagcagcaggagcaggagctgcaacCAGAACAGCAgccggagcagctgcagctgacggAGCAACTGCCTCCGGAGACAGTCACCAAAAAAGTGGAGCAACCGGAAACGGAGCAAAAatcagctgccacgcccaccagcagCGTAACGCCCACAGTGGTGCAGGCGAGCACAATGAAGAGTCTGATTGCCCAAGCGGAGTCCGTGGCGAAATCCCTGAAAGAGGTGGCCAGTTCACCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAACGCGACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGACTGGTGGCCTCGGGCAGCGCCagcgagagcaacaacagcggcaccGAAGAcgtcaccagcagcagcagcagcagctgctgcaacgaACCGAAGAAGAAGTCCGCCTACAGTCTGGCCCCGAACCGGGTCAGCTGTCCGTACTGCCAGCGGATGTTTCCGTGGAGCAGCTCGCTGCGCAGGCACATCTTGACCCACACGGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGGCATCTGTTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTGTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCGGTGCCCAAATCCGTCGAGGAGATTGAGCTGGAGGAGCAGCGACGTCGCCAGGCGGCGGAACTGGAACGGGAGCGGGAAAGGGAACGCGAGCGGGAACTggaacgggagcgggaacgggagcgAGAGCGTGAACGCGAAAAAGAGCTGGAACGGGAGCGTGAGCGGGAGCGGGATCTcatccagcagctgcaggcggcgGCGCAAATGGCCGCCGCGGTTGCGGTTGCGGCAGCTGCGAACGCCGGCGAACCGGAATCGAATGGCAGCGAATTGCCATTCAAGTGCCACCTGTGCGAGTTCTCGTTCGGCGAGCGGATGCAGTGCCTCGAGCACATCAAGCAGCTGCACGAGCACGAGTTcgccctgctgctggccaaaggGGCCATCGAaacggagcagcagcagcagccacagcagcagccacaatcgACACCAGCTGCGGTCCACTCCGAGGATGAGTCCAGTGCGGGACCGGGCGCAGCGCGCGCCGGCAAATACCCGGACTATAGCAACCGTAAGGTGATCTGTGCGTTTTGCGTGCGTCGCTTCTGGTCGACGGAGGATCTGCGCCGGCATATGCGCACCCATTCCGGCGAGCGGCCGTTCCAGTGCGAGATCTGTCTGCGCAAATTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGCCACAACGGGGAGCAGGGCGGCTCCGATTGCTCCGACGATGAGCAGCTGGCGACGCCGCCAACAACGCCAGCGCCAACGCCGCtgcccaacaacaataacaacaacaacaacaataacaacaacaatagttgccacaacaataacaacaacaacagcagcaacaacaacaaacgactGCCAAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTGAGTCGCCTCGGCGAGCACAAGGAGAACATCGCAGAGGCGAcgacggccacgcccaccgcggCCAGCGGCGATCTGATTGGAAATCTGCTGGGGATCAGCGATCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCCGCCAAGCTGCTGGGCGTGGacaagtaa
Protein Sequence: MFMLSLSNYSLNAHVNPNAKHSRQAAAVYDLN*PTFTTTAAAKMLATQQQQQLTATAAAATTTAAAATAATAAAATAATTTAATVALEGAVMERQRRDSSTSESSLEHLDLGRTPKKLCSVGGAPQPTSTPHEATSRKRKLRQQQQQQQQQHLLSDEEEEQLQLQRLRDKQRRSAAASASIVVDYSASGDASSLRKKFRLNRSATNGELGESGFVDGSASSAFLQSSVGGGSGGGSAVQASATAPLLASSSSSSSSGGSSPQDLCHSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCPLTFTTNGNMHRHMRTHKEHQQQQQQHSQQQQQSQQHSQQQHSQQQHSQQQQRRQQVQGASYESDASCSTDVSSGSSSSHNNNNNNNNNNNSQKTNNNNNVEEEEDERQLLQACKRRRHKTNINNNNIILSDERELDSEQEQEQEPEHEQDQDLDQDQDQDMAQLITSTPDVDTLLASGGSSPAPASPPSLVNCPACDSGEFETLAALWQHLDEQHADIPAKCRDCDVIYATHRQLQAHSCRGAGLPPLIGTSSSPLHKQELPDELDADEEPEANERELNSEERDEFFQQLYLKGKSGGQLPSPIKHEPSDHRQDLADIQSILQMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCTYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEEPAATAAATTTNSKPTTTAAAATNQLDLNDLSYRSLTPPPPPPAALELSSSSQLKHMLLAEALPAKTPLKIQVKSLDQLVEKPVEQLTEKSVIDLSMDVLDLSKKPATTTLVEREREREREREREREHELLMQQQQQQQQQQQQQQLFGDPATQYMQQLLRNLMFQQSSGFPFFGFMAPPANLEKSLAAAAAATATQTAAAAPVVAAPVAAVPPPLGLPLAAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCTARFTLRSNMERHVKQQHPQHYAQRQRSGHHVLRGRAANSGAAAAAAAAAAAAAAAAAAAAMSQQHVHPHPHSHPHSHALAPHPAPISDHVKYAILAQQLKARKDTDLLQQALAHGSSSIATHPLLQANYTKSASNNLDDDEPPKLIIDEDDEEDFDEVEEDDDEEEEEEELLEQEQQQEQELQPEQQPEQLQLTEQLPPETVTKKVEQPETEQKSAATPTSSVTPTVVQASTMKSLIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSCCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAELERERERERERELEREREREREREREKELERERERERDLIQQLQAAAQMAAAVAVAAAANAGEPESNGSELPFKCHLCEFSFGERMQCLEHIKQLHEHEFALLLAKGAIETEQQQQPQQQPQSTPAAVHSEDESSAGPGAARAGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGGSDCSDDEQLATPPTTPAPTPLPNNNNNNNNNNNNNSCHNNNNNNSSNNNKRLPKLHELLDKANEWRVSRLGEHKENIAEATTATPTAASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567720;
90% Identity: iTF_00567720;
80% Identity: -