Dpar010118.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila paramelanica
Gene Symbol
-
Assembly
GCA_035043915.1
Location
JAWNMO010000617.1:7174327-7176280[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.9e-08 4.6e-06 26.7 1.9 1 102 23 129 23 135 0.90

Sequence Information

Coding Sequence
ATGCTGCCATCTCCCATGGTGCAACCCACTTTGCACCAGCCGCTGCACTCCAAGGTCTCCAACTACTTAAACAATCAACGACGCACGGGACAGTTTTGTGATTTACAGTTGCAGCTCGATTCGGACGATGCATCCTGCACATGTAGTGCACATTTCTGCGTGGTGGCCGCTCAAAGTCAGCTCATTGGAGTCAatcagcagaagcaacaacagttcTCCATACAGAATCCGCTAAAGGTAACCATACGCAATTTTAACTGCAGCGTGTGCCTGCACACCATAGTCGATTTTTTCTACGAGGACATTGTTTCTGTGTCCAAAGAGCATGAGGAGCACTTTCGTGAGCTAGCCAAAATACTTTCCGTTACGGAGCTGTTGCATTTATATCAAATAGAACAGTCCAGCGATGTGAATACGGGCGTGGAGCCGACAGCAGTGAAAGCCGGAGAAGTGGAGGATAATATGCAGCCGGCTAAAATGCCGGATGTTGTTTTTGAGAATCAGCAAAGCTATTTTAAGCTGAAAAATCCGCGCGCTGTCAAATCCAGCAGCAAAATCAACTATTGCATTGGCTGCGATTTCAAGTGCTACCAGGTGCAAAAGATGATCGATCACATGACCAGCTGCGAGCCGTCGCACCTGACATGCTCTCTGTGCGAAGTTGGCTTTCTGGACTGGCGGGAATACGATGCGCATCTGCGTCGACATGGCTCCGATCTGCGCAAACCCTTCTTCTGTCTGCAGTGCGATAATCGGTTCAGCACCCGCGCAGCTCTGCTTATCCATCAGCCCAAGCACTCGACGGAAACGCCCCATGTGTGCACGCACTGCGGCAAGGCCTTCAAGTGGAAGCAAGGCCTGAGTAATCACATGCTGGTGCACAATCCAGAGAAGCAGATGCTCTGCGATGTCTGCGGCTACAGCACCACGCACATGAAAGCCCTGAAGAGTCACAAACTGTTGCACACCGGCGAATATTTTGCCTGCACTGTGGCTGGCTGCAAGCATCGCGCAAACCGCAAGGAGAACATGAAACTGCACATCGAGACGCACAAACAGGGACGCGATTTCATTTGCGAGATCTGCGGCTGTAAGTTCAGCCAGAGCAAGAATCTAAAACGACATGCGTTGAAGCACACCGAGGGTGGCCTCAATCGTTACAAGTGCCAGTTGTGTGGATTCAGTAGCCATCGCTCGGACAAGATGAAGGAGCACGTGCAGCGCGTGCACACGGAAAAAGCGGTGCAACTGGAGCTGTCCGAAACAGTGGATAGTTcgtttgaaaacaaaatgccagATGATTTTGTTCTGCCGCCCATCGATGCGTTGCCGGCTAATGCGAAGGATACCCGAAAAAATACAACGGAAACTTTGCGACATAATCGGAAAAAATTGCCAGAATTGACGACCACAGCTGTGAAACGTCTAAAGAAACTACTGAAGCTGAAAAGACGTCGCTTGGAGCCAcctaacaacaaaacaatcaaCATGTCCGAGGCACGTTTCGATGAATACGAACACTACAATTTCGACCATGGCAAACACATCTTCAGCGGCCACAGCGGCAAGCAGCGCTCCAAGAAGGAGGCCAGTGAACATACCAATCATAACGATCCCTGCGGCCATTCCAGAAAAATTCTAACGAAGCTCGTGaacaccaataacaacaaaaaaacgtgCAAAAACTAA
Protein Sequence
MLPSPMVQPTLHQPLHSKVSNYLNNQRRTGQFCDLQLQLDSDDASCTCSAHFCVVAAQSQLIGVNQQKQQQFSIQNPLKVTIRNFNCSVCLHTIVDFFYEDIVSVSKEHEEHFRELAKILSVTELLHLYQIEQSSDVNTGVEPTAVKAGEVEDNMQPAKMPDVVFENQQSYFKLKNPRAVKSSSKINYCIGCDFKCYQVQKMIDHMTSCEPSHLTCSLCEVGFLDWREYDAHLRRHGSDLRKPFFCLQCDNRFSTRAALLIHQPKHSTETPHVCTHCGKAFKWKQGLSNHMLVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEYFACTVAGCKHRANRKENMKLHIETHKQGRDFICEICGCKFSQSKNLKRHALKHTEGGLNRYKCQLCGFSSHRSDKMKEHVQRVHTEKAVQLELSETVDSSFENKMPDDFVLPPIDALPANAKDTRKNTTETLRHNRKKLPELTTTAVKRLKKLLKLKRRRLEPPNNKTINMSEARFDEYEHYNFDHGKHIFSGHSGKQRSKKEASEHTNHNDPCGHSRKILTKLVNTNNNKKTCKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00479777; iTF_00549665; iTF_00549857; iTF_00554497; iTF_00560609; iTF_00573441; iTF_00482370; iTF_00499170; iTF_00532674; iTF_00544610; iTF_00805314; iTF_01327458; iTF_00518723; iTF_00557315; iTF_00564771; iTF_00576643; iTF_00520036; iTF_00553156; iTF_00582372; iTF_00803940; iTF_00537829; iTF_00570693; iTF_00574181; iTF_00803173; iTF_01555525; iTF_00511590; iTF_00538534; iTF_00573638; iTF_00583078; iTF_00620166; iTF_01324262; iTF_01326534; iTF_01554278; iTF_00495975; iTF_00496167; iTF_00520231; iTF_00832295; iTF_00513576; iTF_00519496; iTF_00545544; iTF_00567112; iTF_00567848; iTF_00486153; iTF_00540489; iTF_00549129; iTF_00806089; iTF_01320585; iTF_01551305; iTF_01554825; iTF_00476746; iTF_00479594; iTF_00511402; iTF_00513034; iTF_00538346; iTF_00542026; iTF_00553994; iTF_00589834; iTF_00608746; iTF_01328010; iTF_00510123; iTF_00520747; iTF_00530379; iTF_00582571; iTF_00583819; iTF_01321483; iTF_00495244; iTF_00528364; iTF_00576460; iTF_00610028; iTF_00619980; iTF_01322220; iTF_01325964; iTF_01555020; iTF_01560012; iTF_00495437; iTF_00570509; iTF_00586989; iTF_00610221; iTF_01551117; iTF_00512846; iTF_00572718; iTF_00598990; iTF_01325038; iTF_01558606; iTF_00493775; iTF_00496751; iTF_00547471; iTF_00552431; iTF_00558223; iTF_00572911; iTF_00586799; iTF_00803727; iTF_01325231; iTF_01557679; iTF_00509392; iTF_00541872; iTF_00548944; iTF_00566928; iTF_00597520; iTF_01356432; iTF_01559344; iTF_01570512; iTF_00508465; iTF_00521521; iTF_00544049; iTF_00545361; iTF_00557457; iTF_00558865; iTF_00561329; iTF_00593233; iTF_01322769; iTF_00496946; iTF_00498994; iTF_00558034; iTF_00562770; iTF_00568562; iTF_00574386; iTF_00608562; iTF_00614482; iTF_00528179; iTF_00532499; iTF_00535635; iTF_00596051; iTF_01550579; iTF_01559155; iTF_00472660; iTF_00500436; iTF_00502644; iTF_00551892; iTF_00577172; iTF_01323508; iTF_01327284; iTF_01328180; iTF_00485973; iTF_00562581; iTF_00568373; iTF_00589653; iTF_01324469; iTF_01553557; iTF_01557141; iTF_00502102; iTF_00502838; iTF_00530518; iTF_00535446; iTF_00540662; iTF_00547638; iTF_00593430; iTF_00595542; iTF_00806262; iTF_01325782; iTF_01557878; iTF_00497719; iTF_00522519; iTF_00559607; iTF_00564951; iTF_00599159; iTF_00472472; iTF_00473368; iTF_00543864; iTF_00551704; iTF_01326744; iTF_00476921; iTF_00493977; iTF_00525465; iTF_00832473; iTF_01322969; iTF_00497530; iTF_00518554; iTF_00522330; iTF_00542714; iTF_00554682; iTF_00599706; iTF_01320762; iTF_01323674; iTF_00498267; iTF_00553339; iTF_00553819; iTF_00583259; iTF_00589115; iTF_00596219; iTF_00510844; iTF_00513756; iTF_00520924; iTF_00537628; iTF_00542556; iTF_00560412; iTF_00577340; iTF_00583996; iTF_00802972; iTF_00805532; iTF_01322044; iTF_00498429; iTF_00509213; iTF_00521725; iTF_00559069; iTF_00473182; iTF_00525278; iTF_00559806; iTF_00588958; iTF_00595358; iTF_00598462; iTF_01321310; iTF_01552766; iTF_00500607; iTF_00508671; iTF_00516575; iTF_00614303; iTF_00482560; iTF_00501920; iTF_00516384; iTF_00544800; iTF_00552608; iTF_00561152; iTF_00597728; iTF_00598272; iTF_00599904; iTF_01554080; iTF_01555712; iTF_00517282; iTF_00531265; iTF_00506434; iTF_00475335; iTF_00534697; iTF_00475532; iTF_00514477; iTF_00490895; iTF_00534898; iTF_00517107; iTF_00551156; iTF_00491094; iTF_00506233; iTF_00617018; iTF_00531068; iTF_00551004; iTF_00563292; iTF_00563486; iTF_00617214; iTF_00523074; iTF_00575713; iTF_00528931; iTF_01549867; iTF_00575949; iTF_00523282; iTF_00529138; iTF_01549683; iTF_00507220; iTF_00506999; iTF_00586083; iTF_00585539; iTF_00602155; iTF_00534188; iTF_00585332; iTF_00586266; iTF_00569092; iTF_00479049; iTF_00470991; iTF_00471161; iTF_00569276; iTF_00478846; iTF_00587722; iTF_00587525; iTF_00526892; iTF_00526694; iTF_01556397; iTF_01556233; iTF_00584530; iTF_00584710; iTF_00546773; iTF_00546983; iTF_01549206; iTF_01548974; iTF_00901624; iTF_00901809; iTF_00610971; iTF_00610778; iTF_00607198; iTF_00607399;
90% Identity
iTF_00495975; iTF_00496167; iTF_00567848; iTF_00542026; iTF_00547471; iTF_00541872; iTF_00561329; iTF_00547638; iTF_00589115; iTF_00588958; iTF_00598462; iTF_00561152; iTF_00598272; iTF_00805314; iTF_00803940; iTF_00803173; iTF_00803727; iTF_00802972; iTF_00805532; iTF_00512846; iTF_00513034; iTF_00529138; iTF_00528931; iTF_00530518; iTF_00530379;
80% Identity
iTF_00567848;