Basic Information

Insect: Drosophila oshimai
Gene Symbol: zfh1
Assembly: GCA_018150695.1
Location: JAECWM010000267.1:1003768-1007973[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.7e-05 0.0027 18.0 1.1 1 23 142 164 142 164 0.97

2 15 0.00076 0.057 13.9 1.2 3 23 172 192 170 192 0.94

3 15 0.00025 0.019 15.4 0.2 1 23 346 368 346 368 0.98

4 15 0.00012 0.0089 16.4 0.7 1 23 374 396 374 396 0.98

5 15 1.3e-05 0.00097 19.4 2.3 1 23 427 449 427 449 0.97

6 15 0.0039 0.29 11.7 2.0 1 23 479 501 479 501 0.94

7 15 0.0099 0.74 10.4 1.3 1 23 507 530 507 530 0.97

8 15 0.024 1.8 9.1 0.4 3 19 539 555 538 556 0.95

9 15 0.00014 0.011 16.2 5.6 1 23 565 587 565 587 0.97

10 15 0.043 3.2 8.4 0.4 2 23 593 614 592 614 0.96

11 15 8.5e-06 0.00063 20.0 1.0 1 23 623 645 623 645 0.98

12 15 0.00096 0.071 13.6 0.1 3 23 653 673 651 673 0.97

13 15 5.1e-05 0.0038 17.6 0.5 1 23 679 701 679 702 0.95

14 15 0.034 2.5 8.7 0.3 1 23 712 734 712 734 0.97

15 15 0.0051 0.37 11.3 0.2 1 23 1260 1282 1260 1282 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.7e-05	0.0027	18.0	1.1	1	23	142	164	142	164	0.97
2	15	0.00076	0.057	13.9	1.2	3	23	172	192	170	192	0.94
3	15	0.00025	0.019	15.4	0.2	1	23	346	368	346	368	0.98
4	15	0.00012	0.0089	16.4	0.7	1	23	374	396	374	396	0.98
5	15	1.3e-05	0.00097	19.4	2.3	1	23	427	449	427	449	0.97
6	15	0.0039	0.29	11.7	2.0	1	23	479	501	479	501	0.94
7	15	0.0099	0.74	10.4	1.3	1	23	507	530	507	530	0.97
8	15	0.024	1.8	9.1	0.4	3	19	539	555	538	556	0.95
9	15	0.00014	0.011	16.2	5.6	1	23	565	587	565	587	0.97
10	15	0.043	3.2	8.4	0.4	2	23	593	614	592	614	0.96
11	15	8.5e-06	0.00063	20.0	1.0	1	23	623	645	623	645	0.98
12	15	0.00096	0.071	13.6	0.1	3	23	653	673	651	673	0.97
13	15	5.1e-05	0.0038	17.6	0.5	1	23	679	701	679	702	0.95
14	15	0.034	2.5	8.7	0.3	1	23	712	734	712	734	0.97
15	15	0.0051	0.37	11.3	0.2	1	23	1260	1282	1260	1282	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGAGATATGGCGGGATCCAGTGGATACAGCACCACGTCTCCTCCGAGGTGGACATTCTGGAGAACGACGCCGACGGCGAGCTGGTCGTTGGAGAGGGGACGTCGGGTGAGGACCTGGACCATATGGCCGCCGAGAACCTGATATTCATGGCGCGCGACGGGCAGCTGAGCGAAATCATAGCGGCCAGCGAGTCGGGTGGAACTGTTTTGGTCACAGCCGACGGCACCACAGTGGCCTACGCTGAGTCCTTTGATGACGACGCCCAGGTGGTTACCGAGGAGGTTATCACGGACGACTGGGTGCAGCACCAGGGGGCCGAGCGTGTGGAAATCGCCGCAGAGCAGATAGCTGGCATCAGCAGCTCACAGGAACTCCTAGACATGGAACAGGACGAGTACACGGCCTTGAGACCTTATCCCTGCGACTTCTGCAGTCGTCGCTTTCGGAAGAAGGCCACGTTGAACAACCACATGCTGGCCCACCAAAACGATCGGCCGCATCTCTGTAAGCTGTGTGGAGCCCGATTTTCCCGACGAGCCGAGCTCATCAGTCACTTCAAGGCCCACGCAGAGGCCCAGGATGCAGCCGATGCCGAGGCAGCAGCAGCTGCAGCCGATTCCTCCTCCTCCATTAAGTTCGAGCACCAGTCCCAAAGGCAGTTGGACGATCACTACTACGAGCACGAGCAGGAGTGGCCAGTTTACCAACAGCAGCAGGAGCAGGAGCAGATGCAACATGAGCAACTCCAGCAGCACCATCAGATCGTCTCAAGGAGCGAGGTGCAGGTGGTGGCCAGCTACTCCACCGCAGTTGCTCCCCAGGCAGTTCCAGCGCGCGGTAGAATTAGTCGGCTGAAGCCCAAGGAGGAGAGCAGCCACTTTATCGTGACATCCGACAAGCCGGCGGCGAGCGAGTTGAGAGATTACATGGACAGTGAGCCGGCTCAGCCTGTCACTACGTCGCAGCCCATCGTTGACGAGCCTCCCGCCCGTCCAAACTTCCCAGTGCTGGACGACAGCAAGCCCTTTGTGTGCCAACAGTGCGGGTTGGCCTTTGCCCGGGAAAAGGCTCTTGTCTCACACACGAAGAACCACCGCGTGGACTCGCCATTCGAGTGCAATCAGTGCCAGGAGATGTTCTGGGACAACAGCAGTCTGCAGGAGCACCAAAAGACGCACCAGTTCGAGGAAAGCAACTCGGAGTACGATCCTGCGTCCGCGGAGGATAGCGCCAGTGAATCGGAGCCAGAGGAGCAGTTGTACGGCGACTTCTACTGCAACGAGTGCGGGATCTCTTTCCACCGCCAGGATCTGCTGCGGCGCCACGCCAAGCAGCACTTCAAGCAATCGGATCAGGCGGCTGGAGAAGGCCACTTTGATGCCACTGCTGGCGGAGATGTGGAGCTTGCCAAAGATACAGGCGGTCACTGCTGTCACACGTGCGGAAAGTCCTTTCCCAGCGCCCTGGAGATGCTCGCCCATGCCGAAATACACGCCAGGTTTCCGCCCTTTAAGTGCGTCCTGTGCGGAATAAGCTTCTACGAGGAGCAGGCAATCAAGCGTCACCTGCACACCCGCCACTCTAGTGAACTAAAGGCCAACTCCTGCGTACTGTGCGGCAAGGAGTGCCGCGATCGCAAGGCGCTGATCAAACACGCCTGGGACCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCGCGCCTGAAGCGGCACATGGCCTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCAGGAGGAGTTCCCCGACGGGCGCACGTTGTCCAACCACCGGCACTCGCACAGCACCACCTCGCCAGGCAAGCTGTTTCCGTGCCACGAGTGCGGCAAAACCTTTGGATCACGGAGCTCCCAGCAGATTCACGTGCGCATCCACACTGGCGAGCGGCCTTACGGCTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGTACGCTGCGCAAGCACGAGCGGATCCACACGGGCGAGAAGCCGTACGCCTGCTCCGTCTGCCCGCGCGCTTTCAACCAGCGGGTCGTGCTGCGCGAGCACATCCGTTCCCACCACTCGGGACTGGATGTCGCACGGAACACGTACCACTGCACCGTCTGCTCCGAGGACCTGGCCTCGTCGAACGACCTCATCCAGCACCTCATCCAGCACAGTGACTCAAACACCGCCAAGCAGCGACAGCCCATTACGGGACCGCGGAAGTACAAGCGGCGTCGCAAGCTGCAGCCGCATGAGATCGCCCACATGCGAGCGGAGCACAAAGACGCCAATGGCGACGAGGATGTTCTTGGAGAAGGCGAAGAGTACGCCAGCGACATTGATCTATGCGACTTTGATGTGGAGAACGTGGACGATCTCTTTGACATGGCTGAGTCGCCCAAGAAGGAGAAGCGAAAAAGGGCAACGGCAGCCACAAAGGCTGAGCCCAAGCCCGTGGCCAATGGAAGATCGGCAAAGCTTGCCCCAGAAAAGAGCAAGACCAAGTTGAGATACGACTCCACCAGCAGTCAGCAATCGGATCGCATATGGGAGGAAAAGTTCCTGCACGACAGCCAAGTGGGTCTCTTCCAAATCGATTCGCTCGTTGTGGTCAACGATACTCATCTGCAGCCCGCCAGTTCCTCAGCATCTTCGGCCGTGCCCCTCACAAGAGGTGGGGCCAAGCAGCAGGGAAAAGTGCCAGCAAAGCCTGTAGAAGGAACAGGGAATTTCAATTCCTCTGCAGCCACATCCGTTCCCACATCCTCCGCTTCCACCTCCACTTCTAGCAGTCGCAGCAAGAAGAAGGCAGCAACCACCAAGACAGCCAGCAAAGCACCGCCTGCCACCAATTCGCGACCCCGGATGATTCACACGGAAAAGGCCAAGGTGCCGAGAGCAGTTGGTGGAGAATCCTCTAGCAGTGCGGCCAAGAAAACGCGCTCCAAGACCTATATCAGTCGCACGGAAACAAGCAATCTGGGCCTGGACAAATCCCGCAGCAGTGCCTCCAACATGGTGGATGACTATGAAATCATTTCTCCGGCCACCCATCCACCGAATCAGATCAGCTCCAGTCCCTTGCACATCAAACAGGAGCAGGAGCAACAGCACCGTGTCCAACTGATGTACGATGATAATCTTCTGATAGACGCTGCTCTGCTGAGGGAGAAGACGTACGAAAAGTTCAACCCAAGCATTGTTAACGACCTGGAGGAGATTCTACGCTCGCCCCTAAAGCACGAGAGGAATTCCCGTCTACGCTTCACCAGCGAGTCCTCGACCACGCCACAGTTTCTGCCCGAAGAGGAGCAAAATCTAATCAAGATCGAGCCAACGTCTCCGGACTTGCGGGAAATGGTGGAGAGTCAGCAAAGAGTCACAGCTCCAAGTGGAAGCACTCCATCGTCCTCTTCCTCTGCCAGAACTTCCAGACATCTGCGACAGATTACTGCCAATGGTGCAAGGGCAGGGAGCAAAAGATCAGCAGGAAGCGTTGCCAGCAAATCCTCACCAGCCTCGGGAGTGGCCACCAAAAAAGCCAACACTGCCACCAGGGTCAGCAGCTCATCCTCCTACCTAAGCTACGGGGTTGATGCCTACAATGTGAACGTACCTGCCAACGCCAGCAATGGCGATGTGGGCAGCGGATTCTTTTCCATCTCGGAGGTCGTATCCGCTGCCGATGCTGCGGATGCGGCTGCCAAGGCTGCGGCGGCTGGTAAATCGGAGCGTAAAACTCGCAGCTTTGAGTGCGAAATGTGCTCGGCCATCTTCTATGATCGGGCCCAACTGCTGGAACATGTGCACATCCACATCTAG
Protein Sequence: MNNQRYGGIQWIQHHVSSEVDILENDADGELVVGEGTSGEDLDHMAAENLIFMARDGQLSEIIAASESGGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKATLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAADSSSSIKFEHQSQRQLDDHYYEHEQEWPVYQQQQEQEQMQHEQLQQHHQIVSRSEVQVVASYSTAVAPQAVPARGRISRLKPKEESSHFIVTSDKPAASELRDYMDSEPAQPVTTSQPIVDEPPARPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQEHQKTHQFEESNSEYDPASAEDSASESEPEEQLYGDFYCNECGISFHRQDLLRRHAKQHFKQSDQAAGEGHFDATAGGDVELAKDTGGHCCHTCGKSFPSALEMLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHSSELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDANGDEDVLGEGEEYASDIDLCDFDVENVDDLFDMAESPKKEKRKRATAATKAEPKPVANGRSAKLAPEKSKTKLRYDSTSSQQSDRIWEEKFLHDSQVGLFQIDSLVVVNDTHLQPASSSASSAVPLTRGGAKQQGKVPAKPVEGTGNFNSSAATSVPTSSASTSTSSSRSKKKAATTKTASKAPPATNSRPRMIHTEKAKVPRAVGGESSSSAAKKTRSKTYISRTETSNLGLDKSRSSASNMVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVQLMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTAPSGSTPSSSSSARTSRHLRQITANGARAGSKRSAGSVASKSSPASGVATKKANTATRVSSSSSYLSYGVDAYNVNVPANASNGDVGSGFFSISEVVSAADAADAAAKAAAAGKSERKTRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605719;
90% Identity: -
80% Identity: -