Basic Information

Insect: Drosophila ochracea
Gene Symbol: ush
Assembly: GCA_035044125.1
Location: JAWNML010000059.1:10361982-10367359[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.053 3.3 8.2 0.0 1 20 238 257 238 259 0.89

2 9 0.00031 0.019 15.3 0.8 1 23 314 336 314 336 0.98

3 9 0.055 3.5 8.2 1.0 2 21 387 406 387 407 0.92

4 9 0.038 2.4 8.7 3.0 2 21 794 813 793 814 0.93

5 9 0.0099 0.62 10.5 0.0 3 21 864 882 862 883 0.91

6 9 0.02 1.3 9.6 0.0 2 23 953 974 952 974 0.98

7 9 0.0042 0.26 11.7 1.3 1 23 980 1002 980 1002 0.99

8 9 0.0013 0.084 13.3 1.8 1 23 1067 1090 1067 1090 0.96

9 9 0.33 21 5.7 0.7 2 20 1200 1218 1199 1220 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.053	3.3	8.2	0.0	1	20	238	257	238	259	0.89
2	9	0.00031	0.019	15.3	0.8	1	23	314	336	314	336	0.98
3	9	0.055	3.5	8.2	1.0	2	21	387	406	387	407	0.92
4	9	0.038	2.4	8.7	3.0	2	21	794	813	793	814	0.93
5	9	0.0099	0.62	10.5	0.0	3	21	864	882	862	883	0.91
6	9	0.02	1.3	9.6	0.0	2	23	953	974	952	974	0.98
7	9	0.0042	0.26	11.7	1.3	1	23	980	1002	980	1002	0.99
8	9	0.0013	0.084	13.3	1.8	1	23	1067	1090	1067	1090	0.96
9	9	0.33	21	5.7	0.7	2	20	1200	1218	1199	1220	0.91

Sequence Information

Coding Sequence: ATGGGGGAGAAGTGGGCGCGGTCAACGCGCATTGGCGGCCCGCACGAGAAGCAGacgaagcagaagaagcagaaactCGTGGAGCTTATCGGCGCCTTCATATCTATCGCAGCCGTGTTCTGTGTGTATGCCTCTCCACTGTGCACCGTCTTATCCGCCGCATCGCTGGTcgttataatattttATTCCAAAGAATTGGCCGCACACGAGCTGAGCGaggagaagcaacagcaacaccagcagcaccaacaacaacaacagcaacagcttgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCTTGCAACCCGTCGAGACTGACATGGAACAGGAACTGGAGGAGGCGCAAGCGGCAGCCCAGGATTCCAGCGACCAGAAGTTGGCGGACAACCCGACCACGACAACGCCGCCGCGCAGCCCAACGCCTGGAGAACTGGTGCCAAAACTGGAGAGAGCTGATACGCCCCCCTCAGTTCCAGTCACGCCCAGTCCACCACCGCGCACGCCCACACCACCGCCAATTGTACTGCCCAAGCTGCGACTAAATGCGTTGCTTGCCTCAGATCCGGCATTGAAACCCGATGCCAAGGAACTAAATTTGCATGAATCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAGCCGACTCTGCAGCCGGATGTGGAGCCGCTGTTGAAACCGGCGCGATTTATGTGCCTGCCGTGCAGCATCGCTTTCAGTTCACCATCAACGCTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGCAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCCAATGCCAACAGTAGCTCCAGCGGCTCAACTGCCGCCGGCTCCGAGCCGCCCAACAAGGTGTCCCGCATTGGCAAGCAATATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAACCGACACATGCGCATGCATCAAACATCCCCAGCGGCTCCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAAtggtgttgttgccgctgctgctgccgccgctgcggcggctgctgctgctgctgctggtgcgcAGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCATTACTGCAGCTCCCGTCGCAGCGACGGACAATTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGTACTgtagttggagttggagttggtgGAGCTGGTgctagtggtggtggtggtggtggagctgcatcagttgctgctgttgctgccggcaAGCATAGTCCACAGACGCGCAACAAGACGCCAACGCCAGCAATGGTTtgtgctgccgccgccgcagctgcagctgctgctgcctcgcTGCAGGTAGCACCACCGCAACCCTTCCTAGCGCTGCCCACCAATCCGATTATCATAGTGCCCTACTCGCTTATACGTGCTGCCAGTTTGATACCGGGACCACTCACCACTTCTACGTCGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACGGCTCTAAACATAAATACGCTAGGGGGCAGTGCCACGCCTACGCCTACGCCTATGCCCAGCAGCAATCAGATACCGATGCCCGCTTTAGAGCCAGATCGTCCAACTCCTGTGAGCATTTCGAGCAACCTGGAAACGGAACCCAAGAAAAGTCCAGCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACGCCACTGGATTTATCGCTAAGACGCTCGCCAATTGCAGCGCTGTTGCAGCGCCAGCGTCTGGCGCGCTCTGCCGCTGCATTGCTCGACGCCGAGGATGCTGCAGGCAAGGATGCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCAGAGCAAATTGTTTGTGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCTGGAGGTGGCAGCGCTTCGTCGATGTCACCGCCAGCCCATCATATGCTGGATAATTTGCCGCCGTTGCGCTCCATGCTGCCCTCCGATTTTAATCTCTCCGAATCGCTGCTGGCCAAAACGAATCCAGAGTTGGCCCTCAAACTggctgcggcagcagcggctgctgtgGCTGGTAGTGGCTCGGCGGAGCTGGCCAAACTAGGATTTCCAGGAGCTGGTACAGCACCCAGCAGTAGTGCTGCTGCACCATCCTCTGCACAGAATGCACCGCAGATCTATGTGAAGCAGGGCGTCTCCAAGTGCAAGGACTGCAACATTGTCTTCTGCAAATATGAGAATTACTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAGACGGGTCTGGATGGGGATGCCTCCAAAAGCGCTGTAACGCCTCCCAGTGGACTATCATCAGTTGGCGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCAGCCTGCGGCATTAAATACACCTCGCTGGATAATTTGCGTGCGCATCAGAATTACTACTGTCTGAAAGGAGGCgctgcggcagctgccacGCCAGCTGaggcagcaccagcaccacaacTGCCACTCGCCCATCCCAAGGAGAAGTGCCCGAAATGCAAGACTCATCATGAGCACGGACAGAATTGTCCACCACCCCCACCACCAGCAACTCCACAACTACCTGCTCCCTGCTCCACCTCTGCCACGTCGAATAGTGTCAATAAATGTCCCGTTTGTGGCGTAATTAGTCCCACTGCTGCTCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATTCGCACCCATTTCGATAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACATGCATATTTGAGGAGGATGCTGCAGCggtggcagctgcagttgctgctccaACTCAAACCTTGAATCTAGATCTGCCcgctgtggcagcagcggcggcggcagcagcagcagctcaagaGCAACTGGAACAGCACCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTACAAGGGCAATGTGCTGCGTCACATGAAATTACTGCATCCCCATGTGGCCATTAGTTCGCCCTCCATTTCACCTGAGTCGCGCGAACACGAAGCCAATCCACACGCCCTACCCGAAGTAGCGCTGGTTAATGGGGAACGGGAGGCAGCAGCTGTGCCCAGCTTCCACATTAAAACGGAGGCATTGGATGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTGGCACGCCACTTACCCACATTAAAGCGGAGCCCATGGAACTTGGAGTAGATGTATCAGTACCATCGCTACCCCCGCCGATGGCCAATTCCCCGCTTGGGCCAAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAAACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCGCATCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGTGGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MGEKWARSTRIGGPHEKQTKQKKQKLVELIGAFISIAAVFCVYASPLCTVLSAASLVVIIFYSKELAAHELSEEKQQQHQQHQQQQQQQLEDQAEDEQLEQQSNNSSLQPVETDMEQELEEAQAAAQDSSDQKLADNPTTTTPPRSPTPGELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNLHESRLLGPPPKPEQQPTLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSTAAGSEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAAAAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGITGTVVGVGVGGAGASGGGGGGAASVAAVAAGKHSPQTRNKTPTPAMVCAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPYSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPTPMPSSNQIPMPALEPDRPTPVSISSNLETEPKKSPAEPKRKETSGIRETTPLDLSLRRSPIAALLQRQRLARSAAALLDAEDAAGKDAHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGGGSASSMSPPAHHMLDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFPGAGTAPSSSAAAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQETGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSATSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAAAVAAPTQTLNLDLPAVAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHALPEVALVNGEREAAAVPSFHIKTEALDAPVATLSLVHENNNSPIGTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPHRPEANDSPSPTVGGGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -