Basic Information

Insect: Drosophila ochracea
Gene Symbol: Hr39
Assembly: GCA_035044125.1
Location: JAWNML010000059.1:13885402-13888781[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.7e+04 -9.3 14.7 136 201 153 216 25 221 0.50

2 3 2 1.7e+04 -10.6 27.3 40 147 215 334 188 371 0.34

3 3 3.6e-100 3e-96 323.3 18.3 1 408 506 906 506 906 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.7e+04	-9.3	14.7	136	201	153	216	25	221	0.50
2	3	2	1.7e+04	-10.6	27.3	40	147	215	334	188	371	0.34
3	3	3.6e-100	3e-96	323.3	18.3	1	408	506	906	506	906	0.89

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGTTAACATGTCGACGACGACAGTGACGCCagcgtcgcagcagcagcagcaacagcagcagcagcagcgccacaaTGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGGCAactataataatcataatcacaATCATAATCACAATCACAGCGGCAGCTTGTGCATTCCCCTCGGCGGCAATGGGGAAGAGTCCGATTCGGATGCGGAGCTGGTCAACATTGAGAATCTGAAGGTGCGACGACGTGCGTCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACgaatggcggcggcggtggcggcggcgtcggTGACGAGGAAGAGCTCATGGATACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcaccagcagcagcagcagtgccacAACAATGGCCAGCAGTCAGGTGAACGCCATGTTGCAACCCATCAAAACCGAACTGGAGAACATAGCCGGCgagatgcaacagcagcagcaacagcagcagcagcaacaacaacagcagcagcagcagcagcagcagcaacaacagcagcaacatcagcagcaacaactccagctgcaacaacaacagcaacaacaattgctgccaCTGAAGCAACAGACCTATGCACCGAACAATAAACTGAAATTGGCGCCGACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcatCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCCATTTGCCACTGCTGCCCGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACACACAGCAGCCCCTCCCAGTCGCCGCTTACGTCCCGCCACGCCCCCTATACGCCGTCGCTGAGCAGGAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCCATTCAGGCGCGTCATGCGCCACTCGCTGGCGTCGCTGCCCTGTTCACGGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGCGGGTGGTGCTGCATTGGATGCTAGCGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCACGTCAGCAGCTGATCAATTCGCCGTGCCCGATTTGTGGGGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGATTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgaggcGGACCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTACCAGTGCTCCTATACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCCGATCAGgcggcagccgctgcagccgccgccgccgttgtcaatcaacagcagcagcagcagcatcagcagcaacatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcagcaacaacaacagcaacagcagcagcaacagcagcaacaacatggtCCACTCAATGGctttggtggtggtggctccAATTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAATCGGAGCAGCTAAACCATCATACGTCATCATCAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACGGGTGGCTCATCGTCAACCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATTGCACACCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGACACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGTTGAATCTGACCGATCATTTGCGTCGTCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTCCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTgcagattttaatttgctaatgGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPVNMSTTTVTPASQQQQQQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIGNYNNHNHNHNHNHSGSLCIPLGGNGEESDSDAELVNIENLKVRRRASDKNGPRPMSWEGELSENETNGGGGGGGVGDEEELMDTETVIKSEVSSSTSTSSSSSATTMASSQVNAMLQPIKTELENIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQLQLQQQQQQQLLPLKQQTYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPLAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQHQQQHQQHQQQRLQQHQQQQQQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQSEQLNHHTSSSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSTGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00564700;