Basic Information

Gene Symbol
-
Assembly
GCA_018151105.1
Location
NW:1542921-1543493[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.2 4.1e+03 -2.3 0.0 14 29 14 29 12 32 0.81
2 2 2.4e-21 2.3e-18 65.8 11.0 6 68 85 147 80 149 0.94

Sequence Information

Coding Sequence
ATGGAGGGTTCTTCGTCATGGTTAGGGGACAGCAGGGAACACGGCATGTCGGCTGTCGGATATAAAGCAGGGCTAGGCACGCTCCTGTTGGACTACTCAGCCATGGACGTGGACCTCAAGAGAACAGCCTACTACCCCTATTTGGGGGCGCAGGAGCCTGTACTTGTGCCAGGAACGCAGCCCAATCCTGTTCTGGTGATCAATGCCAATGcagcagaggcacagCCGAAGCTGGGACCTGTGGCTCAGATCTTGTGCTGTCCACACTGCCGATCCACGATGGAGACCCGTCTGGAGCCGCGAGTGACCAAGCATACCcatgcctttgcctttgctctCTGTCTGACGGGCCTGTTCTGCCTGGTGCCGCTGCCGTACTGCCTGAAGAGCTGCCAGAGCGTGGACCATTACTGCAGTCAGTGCAATCGGTTTCTTGGAAAGGCTTCCAGTTAA
Protein Sequence
MEGSSSWLGDSREHGMSAVGYKAGLGTLLLDYSAMDVDLKRTAYYPYLGAQEPVLVPGTQPNPVLVINANAAEAQPKLGPVAQILCCPHCRSTMETRLEPRVTKHTHAFAFALCLTGLFCLVPLPYCLKSCQSVDHYCSQCNRFLGKASS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00518116;
90% Identity
iTF_00611731;
80% Identity
-