Basic Information

Insect: Drosophila obscura
Gene Symbol: Aef1
Assembly: GCA_018151105.1
Location: NW:5965409-5969069[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.0095 68 3.4 0.1 21 46 198 223 193 225 0.87

2 4 2.7e-05 0.19 11.5 0.0 21 52 226 257 223 259 0.89

3 4 0.02 1.4e+02 2.4 0.1 21 48 254 281 251 285 0.86

4 4 8.7e-05 0.62 9.9 0.1 21 47 282 308 278 315 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.0095	68	3.4	0.1	21	46	198	223	193	225	0.87
2	4	2.7e-05	0.19	11.5	0.0	21	52	226	257	223	259	0.89
3	4	0.02	1.4e+02	2.4	0.1	21	48	254	281	251	285	0.86
4	4	8.7e-05	0.62	9.9	0.1	21	47	282	308	278	315	0.88

Sequence Information

Coding Sequence: ATGATGCATATCAAGAGTTTGCCCCATGCTCATGCCCATGCTGCTGCCACGGCGATGAGCAGCAACTGTGACATTGTTATTGTGGCCTCTCAGCCGCAGACGACGattgccaacaacaacaacaatgataCGGTCACACAGGCCACTCATCCCGGTCATGTGGCAGCGGcggcccaacagcagcagcagcagcagcagcaacagcagcagcaggcgcagcagcagcatcaccaacagcagcaacaggcgcaacagcaacaacagtctTCTGGACCCCCCTCAGCGCCACCAGCTCCAGCGGAACTCGCCGCCTTACCCTTCCAAATGCATCTGAATGGAATTTCGGCCGAGGCGCATAGTGCCGCTCAGGCTGCAGCCATGGCGGCTGCTCAGGCCGCAGCAGCTCAAGCAGCGGCGGCGGATCAACAGCAGCCACCGTCAGCGCCTCCACCGCATCTGGTCCATCTGGCCACGCACAGCCCGACCATGTCGAATGATCACTATTTGGCCAATGGCCATGGCGAGCACCAGGGTGAGGGGGCTGGCAGCAATGGAAACTCtggcggtggcggaggcggtggcgcGAGAGACCAGGAAAAGCCGTTCCACTGCACCGTGTGCGATCGACGCTTCCGGCAGCTGAGCACACTGACCAACCATGTCAAGATCCACACTGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACCTTCCGTCAATCGTCCACGCTGACGAACCATCTGAAGATCCATACGGGGGAAAAGCCCTACAACTGCAACTTCTGTCCCAAGCATTTCCGTCAGCTGAGCACTCTGGCGAATCATGTCAAGATCCACACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAAAAGCAATTCCGGCAGTCCAGCACGCTCAACAACCACATAAAGATCCACGTCATGGACAAGGTCTACGTTCCTGTCAAGATCAaaacggaggaggaggaggggtgACTAGGACGGATGGCGTTGGCGgggcatcatcagcagcagcaccatcatctgccgcagcaacagcatccgCACCACCAACAGCCACCGCATCCGCATCATACTCCGCCCCATGCCCATGCACATGCTCATGCCCACCACATCGACCATCAGCGAGGAATAACCATTACCACTCTGCCCTCCACCACGTCTGTGGcgcaacaccagcaacagcagcagctccttcaccatggcaatggcagttCTCCCCACCATTTCAATGTGGCCTCGTTGGGTGATTTGTCCAGCGCCATGCAGCTGGGAGCTGTGACAGCCGATGGCAACTTTGTCACCATGaatggggtggtggtgggccGCATTCAACACACGCGCgaagagctgcagcagctcggaGTGATTAAGGTCGAGTCACCATCGAATGGTGTGACCACCGTGCCGACGTCTGTGGCGTCGTCAACGCAGCGCGAGTGA
Protein Sequence: MMHIKSLPHAHAHAAATAMSSNCDIVIVASQPQTTIANNNNNDTVTQATHPGHVAAAAQQQQQQQQQQQQQAQQQHHQQQQQAQQQQQSSGPPSAPPAPAELAALPFQMHLNGISAEAHSAAQAAAMAAAQAAAAQAAAADQQQPPSAPPPHLVHLATHSPTMSNDHYLANGHGEHQGEGAGSNGNSGGGGGGGARDQEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEEEG*LGRMALAGHHQQQHHHLPQQQHPHHQQPPHPHHTPPHAHAHAHAHHIDHQRGITITTLPSTTSVAQHQQQQQLLHHGNGSSPHHFNVASLGDLSSAMQLGAVTADGNFVTMNGVVVGRIQHTREELQQLGVIKVESPSNGVTTVPTSVASSTQRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591971;
90% Identity: iTF_00564166; iTF_00575110; iTF_00601418; iTF_00601314; iTF_00515253; iTF_00515150;
80% Identity: iTF_00564166;