Basic Information

Insect: Drosophila obscura
Gene Symbol: zld
Assembly: GCA_018151105.1
Location: NW:1616234-1622806[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.019 1.1 9.5 0.1 2 23 127 149 126 149 0.94

2 6 0.0037 0.23 11.7 2.9 1 23 415 439 415 439 0.92

3 6 0.006 0.37 11.0 4.0 2 23 1299 1321 1298 1321 0.95

4 6 0.002 0.12 12.6 1.6 1 23 1327 1349 1327 1349 0.96

5 6 0.0013 0.082 13.1 4.4 1 23 1356 1379 1356 1379 0.92

6 6 3.2e-05 0.002 18.2 6.6 1 23 1385 1407 1385 1407 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.019	1.1	9.5	0.1	2	23	127	149	126	149	0.94
2	6	0.0037	0.23	11.7	2.9	1	23	415	439	415	439	0.92
3	6	0.006	0.37	11.0	4.0	2	23	1299	1321	1298	1321	0.95
4	6	0.002	0.12	12.6	1.6	1	23	1327	1349	1327	1349	0.96
5	6	0.0013	0.082	13.1	4.4	1	23	1356	1379	1356	1379	0.92
6	6	3.2e-05	0.002	18.2	6.6	1	23	1385	1407	1385	1407	0.97

Sequence Information

Coding Sequence: atgcagcagcaaagtTACACCAGCAGCTACATCAACAGCTACGAGCAGttctaccagcagcagcaacaacagcagcagcagcaaagcagcgACTATAGCTTTGGCGGTGGTCTGGTGGGCGGCGGGGACTTCAGCAAGCATGCGGCACAGAGCTCAGGGGTGCGGTACCATCCGTACCTGCAGACGCCGACATCGGCGCTACCCAGCGCCGCGGAGGAGGCGGTGAGTGCTCCCAGTGCTGTGAGTACCACCACATCGGCGATGAGTCCGCGTgtcgtcagcagcagcagtcccacATCGACCTCATCGCACCTCCAGCTGGGCGGAGGACCACCCGGTTCTCCCAGCGGAGCCGGCGGCGGAGGGGGCTGCAAGTTGCAGTGCAAGAAGTGCGGCATTCTCACCACCAACGAAcaggagctgcaggagcacATCGCCAATGTGCACGGAGAGTCGCCGTACGGGAGCAGCGGGTACGCCAGTTCGCCGTACATCAAGGAGGAGATGCCCACCCCTCAGCCACCGGGCGGCTCCAATCCCGGAGAGCTGCTCGACCTCGACTCGCAAAAGATGGTCTACCACCAGCAGTTGcttcagcaacagcagcagcaccagcaacagcagcaccagcacgaGGCTGTCGTCGCCGGCCTGCCTCTGTCGCTGCCCGATCCCCTGCACTCCATGCAGTCCATGCAGCAGCGCGCCCTACACAGCTGGGAGCAGCCGCAGAcgggagtcggagtcggagtcgagGGCCTGCCGCCCtacatgcaacagcagccgggTCTCGGCCTTGGCGTTGGCCTCGGTCTGggcgtcggcgtcggcgtcggcgtAGAGAAGTCGCCGTACTACTCGCCCAAGCAGTCGCCCTACCACCAGGCGGGCGGAGGAGTCGGCGTTGGAGCTACACTCATCAAGCAGGAGTACGGCGGCCACGGGCTGATCAAGTCCGAGTATCCCGACTCGCAGCACTACGTGGACAAGTCGTTCGATCCGACGGCTGGCAGTGGTGGAGGAGTCGATCTGTGCGCCAATGTGGCCACCAGTCCGGCCGAGTTCCCCAGCACTACGACGGGCGGACCGGGCCAGGATGGGGCCCCGCCAGCGGTGGCCGGGGGCCAACAGGCCGCCTACCGTGGCTTCGAGCCGCCCAGCTCAAGCTCCGTGCTGCCGGCCAACAGCCTCACGGCCAAGGCGGCCACCTGGAAGTCGAATGAGGCGCGCAGGCCCAAGACATACAACTGCACGGCCTGCAACAAGTGGTTCACCAGCTCGGGACACCTCAAGCGTCACTACAACACAACGCTGCACAAGAACGCGGTCAAGTCGAGCGGCCAGCCGGATCCAGCCACGCTGCCCATTTCGGCGCACCATCATCCGTCGCGCGATCCCGTAACCAAGCCAAGTCGTCGCGGGAAtgccgccgctgcagctgcggccgctgcagcagctgccgcgGCCGCTTCGGCGGTGCCGCAAGTACAACCACCACCGCCGGCGAATGTGCAACCACCGGAGCCGCCTAGAAGTCCGCCCGATTATGGCGGTGGAGGCGGGGTGGGAGCGGTGGGTGGCGCTGCCATGTCCCAGTACTCGGCCTCGCCATCGCCcaccacgcagcagcagcaccatcaacaccagctccagcagcagcagcagcagcaggccaacgGGAACGGGTATCCGGGTAACGGCGGCGCCAatggctacggctacggcatGCAGCAACAAGTGCAATCCACGACAAACGCTTCACCACAGCACGCTTCcagccatcagcagcagcatccgcattcgcattcgcagcagcagcatcttcaacagcagcagcagcaacaacagcagcagcatagcagcagcaacaacaacaactccgtTTTGAACGGTCACCCAAACGGGCTAGCAGGTCCCTCCGCCCCActcaacaccaacaacaacaacatcacaCAAATGCCGTCCTCCCAAATGAGGGGCCTGCTgaacgaaacaacaacaaccaccaccCCCAAAACcaccccaacaacaacaacaacagccacaatgCCAATGGAAACGGAAGCAATGGCAGCTATAAAGATCGAGCATCTGGAGGACagcaaccacacacacaacagccacaacagccgcagcagcagcttaatggccatggaggaggagcaggatcaggagcgggagcgggcAGTAGATCacctacagcagcagcagcagcagcagctggagcagcaggaacaacagcagcaggtcAGCTATCTGCTGGCATCGGCGGCATCCCGTCCCTACAgctccaacagcaacagcagcaacacgccCAACACGgcggtcagcagcagcagcaacaccagcaacaccagcagcaccagcagcagcagcagcaacaacaacagactCTCGCCCCTTACTATCTACCatcttcagcagcagccgccgctgcggcaggagcagcagcagcagcaggcaatgGATTTCTCGCGCACCACCCCgccgccgcagctgctgccgcctatGGGAATGGGCCAGCCGCAGCAGTCGCTGCTGCCGCCTATGGGAATGGACTACAACATGCTGGCTTTGGatatgcccatgcccatgcacatgcccatgcccagcaGTATgctgcagtgcagcagcaccagcaccacgcCGCTAGCTACTATCACCACCACCAGTATGGACactatgcagcagcagccgcagcagctggTGCACCACTACCAGGCGCTGCTccacccccaccaccaacatcagcagcagcagcagcagttggaggagcagcagcagcaggaggaggaacaacaacagcagcaggaggaggagcatcaTCACCAGCacctacagcagcagcagcagcagcaggatccGGGGGCACTAATCCTATCTCCGGACAATatgccacacagcagcagTTCGCCGGGCACCAGCAGCTctccgccgccgcagcagctgcagcagcagcacacgcACACCACCCTcaccatgcccatgcccatgccgccCACCATGCACATGCCCATCACCACCACAGcgccgcagctgctgccgctgcagctgcagccgccgccgccgcacaTCACCAACACCATGCCCATGCCGCCCACCATGCACATGCCCAtcatgccgccgccgccgccatgctaccagcagctgcagccgctggATCCCACAACGAGCTATCACACTATTATTGGTAGTTCCGTCGCCGAGTCCGGCTACACCACGAACGGGCATCACAATCCCCACGCCCATGCCCACGCCCACCCCCACCAGATCACGACCAGCGACGGCCAGGTCCTGCAGCTGATGCCCGCCTCCCTGTTCGCCCCCTATGCCCCGCTCTCGCCCTACTCGACGGTGGCGGCCCAGCGATCGCCACAGGAGGGGGACCTGCCGCCGGTGCACACCCTGACGACGGCCCTCCAGGCCCACGCCCAGGCACAGCAAGAGCAGGCGCACACGCCCACGCTTACGGTGCTCAGCACCCCCTACTCGCCCACGGTGAGCAGTTCGCGGGCCACGCCCGCCCTGGAGATGGACATGGCCacactgctgcagcagcaacaacagcagcaggactaCGAACTGGAGCAGTACCAGCACCAGATTCAGCAGCATCAGATGGACCAGCTGCATCACCACCAAcagatggagcagcagcaggccctggaacaacagcagcagcagcatcagcaacagcaacagcaacatcaacagcagatGCAACTGGTGGAGatggaacagcagcaacagccgccgACACAAACGGTGGCACAGTCGGTGCCGAAAAAGCGAAGAGGAACGGCCGCCGCCACACCATCCACAACGAAGCGGCGACGCAACAGCAGCGTGAGATCGACATCGCCGCACTCGACAACGCTGCCATCCGGGCGGATCAAGTGTCTGGAGTGCGACAAGGAGTTCACCAAGAACTGCTACCTCACGCAGCACAACAAGAGCTTCCACTCCGGTGAGTACCCCTTCCGCTGCCAGAAGTGCGGCAAGCGCTTCCAGAGCGAGGACGTTTACACTACACACCTGGGCCGGCACCGCACCCAGGACAAGCCGCACAAGTGCGAGCTCTGTCCGAAGCAGTTCCATCACAAGACAGATCTGCGGCGCCACGTGGAGGCCATACACACGGGCCTCAAGCAGCACATGTGCGACATTTGCGAGAAGGGCTTCTGTCGCAAAGATCACCTGCGCAAGCATCTCGAGACCCACAATCGACCCCGGGTTGTGGGCAAGaaatctgctgctgccgccgcagccgccgctgttgtggcagccgctgcagcagcaacagcagcctcgcagtctcagcagcagcagcaacagttggTGACTACCGTTCTATCCACCCTTCCCGCCTCTGACACGCCCACGGCCATCAATCCCATTAAGGCGGCCTTTGCCCGCTCCCTAACGGTGACGGCCGTGTCCGCATTGTCGCCCCGCACCACGCCCACCTCCAATCCGCATCTGAAtgccagtctcagtctcaatCTGAAGCGATCCATCGACGATGTGGCCGCCGACGATGACAGCCTGCTGGAggacgatgaggatgaggaggagggggaggaggagctgctgctggacgagGCTGAGGAGGATCAGATGGTAGAGCAAATGGAGGCGCAGCAAATCCTGTTGGTCACTGCTGCCGCAGGGGACAGTCACCATCTGCTGATCAAGGACGAGTTTCCCGAGGAGGAGTACGAGTTGATTGAGAAAGATATTGAATTGTATTGA
Protein Sequence: MQQQSYTSSYINSYEQFYQQQQQQQQQQSSDYSFGGGLVGGGDFSKHAAQSSGVRYHPYLQTPTSALPSAAEEAVSAPSAVSTTTSAMSPRVVSSSSPTSTSSHLQLGGGPPGSPSGAGGGGGCKLQCKKCGILTTNEQELQEHIANVHGESPYGSSGYASSPYIKEEMPTPQPPGGSNPGELLDLDSQKMVYHQQLLQQQQQHQQQQHQHEAVVAGLPLSLPDPLHSMQSMQQRALHSWEQPQTGVGVGVEGLPPYMQQQPGLGLGVGLGLGVGVGVGVEKSPYYSPKQSPYHQAGGGVGVGATLIKQEYGGHGLIKSEYPDSQHYVDKSFDPTAGSGGGVDLCANVATSPAEFPSTTTGGPGQDGAPPAVAGGQQAAYRGFEPPSSSSVLPANSLTAKAATWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPSRDPVTKPSRRGNAAAAAAAAAAAAAAASAVPQVQPPPPANVQPPEPPRSPPDYGGGGGVGAVGGAAMSQYSASPSPTTQQQHHQHQLQQQQQQQANGNGYPGNGGANGYGYGMQQQVQSTTNASPQHASSHQQQHPHSHSQQQHLQQQQQQQQQQHSSSNNNNSVLNGHPNGLAGPSAPLNTNNNNITQMPSSQMRGLLNETTTTTTPKTTPTTTTTATMPMETEAMAAIKIEHLEDSNHTHNSHNSRSSSLMAMEEEQDQERERAVDHLQQQQQQQLEQQEQQQQVSYLLASAASRPYSSNSNSSNTPNTAVSSSSNTSNTSSTSSSSSNNNRLSPLTIYHLQQQPPLRQEQQQQQAMDFSRTTPPPQLLPPMGMGQPQQSLLPPMGMDYNMLALDMPMPMHMPMPSSMLQCSSTSTTPLATITTTSMDTMQQQPQQLVHHYQALLHPHHQHQQQQQQLEEQQQQEEEQQQQQEEEHHHQHLQQQQQQQDPGALILSPDNMPHSSSSPGTSSSPPPQQLQQQHTHTTLTMPMPMPPTMHMPITTTAPQLLPLQLQPPPPHITNTMPMPPTMHMPIMPPPPPCYQQLQPLDPTTSYHTIIGSSVAESGYTTNGHHNPHAHAHAHPHQITTSDGQVLQLMPASLFAPYAPLSPYSTVAAQRSPQEGDLPPVHTLTTALQAHAQAQQEQAHTPTLTVLSTPYSPTVSSSRATPALEMDMATLLQQQQQQQDYELEQYQHQIQQHQMDQLHHHQQMEQQQALEQQQQQHQQQQQQHQQQMQLVEMEQQQQPPTQTVAQSVPKKRRGTAAATPSTTKRRRNSSVRSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKRFQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRVVGKKSAAAAAAAAVVAAAAAATAASQSQQQQQQLVTTVLSTLPASDTPTAINPIKAAFARSLTVTAVSALSPRTTPTSNPHLNASLSLNLKRSIDDVAADDDSLLEDDEDEEEGEEELLLDEAEEDQMVEQMEAQQILLVTAAAGDSHHLLIKDEFPEEEYELIEKDIELY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471941;
90% Identity: iTF_00603652; iTF_00581093; iTF_00474089; iTF_00518030; iTF_00481142; iTF_00575158;
80% Identity: -