Basic Information

Insect: Drosophila helvetica
Gene Symbol: zld
Assembly: GCA_963969585.1
Location: OZ018401.1:5579549-5584801[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.023 2.2 9.4 0.1 2 23 289 311 288 311 0.94

2 6 0.0046 0.43 11.6 2.9 1 23 578 602 578 602 0.92

3 6 0.0074 0.7 10.9 4.0 2 23 1450 1472 1449 1472 0.95

4 6 0.0024 0.23 12.4 1.6 1 23 1478 1500 1478 1500 0.96

5 6 0.0016 0.16 13.0 4.4 1 23 1507 1530 1507 1530 0.92

6 6 3.9e-05 0.0037 18.1 6.6 1 23 1536 1558 1536 1558 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.023	2.2	9.4	0.1	2	23	289	311	288	311	0.94
2	6	0.0046	0.43	11.6	2.9	1	23	578	602	578	602	0.92
3	6	0.0074	0.7	10.9	4.0	2	23	1450	1472	1449	1472	0.95
4	6	0.0024	0.23	12.4	1.6	1	23	1478	1500	1478	1500	0.96
5	6	0.0016	0.16	13.0	4.4	1	23	1507	1530	1507	1530	0.92
6	6	3.9e-05	0.0037	18.1	6.6	1	23	1536	1558	1536	1558	0.97

Sequence Information

Coding Sequence: ATGGCGAGCATCAAAAGTGAAATGCCGCCACTGCATGCGGCAGAGGCTCTGGCCTCAAGCAGTGCCACAgacagcggcggcggcggcggaggaggaggaggaggagggacagcagctggcagcggcggcagtggTGGTGCTGGGACAGGAGCAGCCGGCGGCGGTGTCAACAGTGCCCCGGCCACCCCAAATGCCACAATAAGCGCCGCAGCCGATTCCAGTGATAACCAGCCCGGCACACCGCAACCacctcagcagcagcagccgccacagcagcagcagcagcaaccacagcagcagcagcaacaaacgcagcagcagcagcagcagagcatgGCCACGGATCCACAGGTAACGGGCATCACCCACCAGCCCTATGCCACCCATCACATGTACTCCGCCAGCGGCcagccccagcagcaacagcagcagcaacagcaacagcagcagcagcagcaacagctgtaCGGCGGCCTCTACGGCGGAgaaatgcagcagcagagctACGCCAGCAGCTACATCAACAGCTACGAGcagttctaccagcagcagcagcaacagcagcagcagagcagcgacTACAGCTTTGGCGGTGGCCTTGGCGGCGGCGGGGACTACAGCAAGCATGCGGCACAGAGCTCGGGGGTGCGGTACCATCCGTACCTGCAGACGCCAACATCGGCGCTTCCCAGCGCCGCGGAGGAGGCGGTGAGTGCCCCCAGCGCTGTGAGCACCACCACATCGGCGATGAGTCCGCGCgtcgtcagcagcagcagtcccaCATCGACCTCTTCGCACCTCCAGCTCGGCGGGCCGCCCGGCTCCCCCAGCGGcgccggcggcggcggagggGGCTGCAAGTTGCAGTGCAAGAAGTGCGGCATCCTCACCACCAACgagcaggagctgcaggagCACATCGCCAACGTGCACGGAGAGTCGCCGTACGGGAGCAGCGGGTACGCCAGTTCGCCGTACATCAAGGAGGAGATGCCCACCCCCCAGCCACCGGGCGGATCCAATCCCGGGGAGCTGCTCGACCTCGACTCCCAGAAGATGGTCTACCACCAGCAgctgctccagcagcagcagcagcagcaacagcaccagcacgAGGCTGTCGTCGGCGGCCTGCCCCTGTCGCTGCCCGATCCCCTCCACTCCATGCAGTCCATGCAGCAGCGCGCCCTCCACAGTTGGGAGCAGCCGCAGGCGGGAGTGGGAGTCGGAGTCGAGGGACTGCCACCCtacatgcagcagcagccgggcCTCAGCCTGGGCCTGGGCGTCGGGCTGGGCGTCGGTGTGGACAAGTCACCCTACTACTCGCCCAAGCAGTCGCCCTACCACCAGGCGGGCGGAGGAGGagtcggcgtcggcgtcggcgtcggaGTCGGAGCCACCCTCATCAAGCAGGAGTACGGAGGTCACGGGCTGATCAAGTCCGAGTACCCAGACTCGCAGCACTACGTGGACAAGTCGTTCGATCCGACGGCCGGCAGTGGCGGCGGAGTCGATCTGTGTGCCAATGTGGCCACCAGTCCGGCCGAGTTCCCCAGCACGACGACGGGCGGGCCGGGCCAGGATGGGGCCCCGCCAGCGGTGGCCGTCGGCCAGCAGGCCGCCTATCGCGGCTTCGAGCcgcccagctccagctccgtgCTGCCGGCCAACAGCCTCACGGCCAAGGCGGCCACCTGGAAGTCGAACGAGGCGCGCAGGCCCAAGACCTACAACTGCACGGCCTGCAACAAGTGGTTCACCAGCTCCGGCCACCTGAAGCGCCACTACAACACGACGCTGCACAAGAACGCGGTCAAGTCGAGCGGCCAGCCGGACCCGGCCACGCTGCCCATCTCGGCGCACCACCATCCGTCGCGCGATCCCGTGACGAAGCCCAGCCGGCGCGGAAATGCCGCCGCCGCGGCtgcggccgctgctgcagctgccgcGGCCGCCTCGGCGGGGCCCCAAGTGCAGCCCCCGCCGCCGGCCAATGTGCAACCGCCGGAACCGCCTAGAAGTCCGCCCGACTATGGCGGCGGAGGCGGGGTGGGAGCGGTGGGCGGCGCTGCCATGTCCCAGTACTCGGCCTCGCCGTCGCCCaccacacagcagcagcaccatcaacaccagctccagcagcagcagcagcagcaggccaacGGCAACGGGTATCCGGGCAATGGCGCCGCcaacggctacggctacggcatGCAGCAACAAGTGCAATCTACGACAAACGCTTCACCACAGCACGCTTCCagtcatcagcagcagcatccgcattcgcattcgcagcagcagcagcagcacctccaacagcagcagcagcagcagcatagcagcagcaacaacaacaactccGTTTTGAACGGTCACCCAAACGGGCTAGCAGGTCCCTCCGCCCCActcaacaccaacaacaacaacatcacaCAAATGCCGTCCTCCCAAATGAGGGGCCTGCTGAACGAAAcaacaaccaccaccacccccaaaaccaccccaacaacaacaccaacagccACGGAAGCAATGGCAGCTATAAAGATCGAGCATCTGGAGGACAGCAACCACACccacaacagccacaacagccacaacagtcgcagcagcagcagcagcagcagcagcttaaTGGCcatggaggaggagcagcagcagcaggagcaggagcgggcGGCAGATcacccacagcagcagcagctggatcagcaggaacagcagcatCAGGTCAGCTATCTGCTGGCATCGGCCTCCCATCGTCCCTACAGctccaacagcaacagcagcagcaacaccccCAACACGGgggtcagcagcagcagcaacacggCCAACACGGCggtcagcagcaacagcagcagactCTCGCCCCTTACTATCTACCAtcttcagcagcagccgccgctgcggcaggagcagcagcagctgcaggcaATGGATTTCTCGCGCACCACcccgccgccgcagccgctgccgcctATGGGAATGGGCCAGCCGCAGCAGTCGCTGCTGCCGCCTATGGGAATGGACTACAACATGCTGGCTTTGGatatgcccatgcccatgcacATGCCCATGCCCAGCAGTATGCTGCagtgcagcagcaccagcaccacgcCGCTAGCTACTATCACCACCACCAGTATGGACActatgcagcagcagccgcagcagctgGTGCACCATTACCAGGCGCTGctccacccccaccaccagcatcagcagcagcagcagcagcagttggaggaggaggaacgacaacagcagcaggaggagcatcATCACCAGCacctacagcagcagcagcatcagcagcagcaggatccGGGGGCACTAATCCTGGCGCAGGACAATATGCCACACAGCAGCAGTTCGCCGGGCATCAGCAGCTCtccgccgccgcagcagcagcagcagcagcccatgcacacccacacccacaccaccctcaccatgcccatgcccatgccgcCCACCATGCACATGCCCatcaccaccacagcgcagcagctgctgccgctgcagctgcagccgccgccgccgcacaTCACCAGCACCATGCCCATGCCGCACACCATGCACATGCCCATcatgccgccgccgccgccatgctaccagcagctgcagccgctGGATCCCACAACGAGCTATCACACTATTATTGGTAGTTCCGGCGCCGAGGCCGGCTACACGACGAACGGGCATCCCCACCAGATCACGACCAGCGACGGCCAGGTCCTGCAGCTGATGCCCGCCTCCCTGTTTGCCCCCTACGCCCCGCTCTCGCCCTACTCGACGGTGGCGGCCCAGCGATCGCCGCAGGAGGGGGACCTGCCGCCGGTGCACACCCTGACGACGGCCCTCCAGGCCCACGCCCAggcacagcaggagcaggcgcaCACGCCCACGCTTACGGTGCTCAGCACCCCCTACTCCCCCACGGTGAGCAGCTCGCGGGCCACGCCCGCCCTGGAGCTGGACATGGCCAccctgctgcagcagcagcaacagcagcagcagcaggactaCGAACTGGAACAGTACCAGCATCAGATTCAGCAGCATCAGATCgaccagctccagcagcaccATCACCACCAGCAACAGATGGAGCAGCAGGCCCTGgaacagcagcatcaacagcagcagcagcagcagcagcagatccaACTCGTGCAGGTGgatcagcaacagcaaccgacGCAGACGGTGGTGCAGTCGGGGGCCAAGAAGCGGAGAGCAACGGCCGCCGCCACACCGTCCACGACGAAGCGGCGACGCAACAGCAGCGTGGGATCGACGTCCCCGCACTCGACGACGCTGCCCTCCGGGCGGATCAAGTGTCTGGAGTGCGACAAGGAGTTCACCAAGAACTGCTACCTCACGCAGCACAACAAGAGCTTCCACTCCGGTGAGTACCCGTTCCGCTGCCAGAAGTGCGGCAAGCGCTTCCAGAGCGAGGACGTTTACACGACACACCTGGGCCGGCACCGCACCCAGGACAAGCCGCACAAGTGCGAGCTCTGTCCGAAGCAGTTCCACCACAAGACCGATTTGCGGCGCCACGTGGAGGCGATCCACACGGGGCTCAAGCAGCACATGTGCGACATTTGCGAGAAGGGCTTCTGCCGCAAGGATCACCTGCGCAAGCATCTCGAGACCCACAATCGACCCCGGGTCGTGGGCAAGAAatctgctgccgccgctgccgctgccactgccgccgcagccgccgccgttgtggcagccgctgcagcagcaacagcagaagcagcagcagcggcctcgcagtcgcagcagcagcagctggtgaCTACCGTTGTGTCCACCCTtcctgtctctgcctctgccacgcCCATCAATCCCATTAAGGCGGCCTTTGCCCGCTCCCTGACGATGACGGCCGTGTCGGCGTTGTCGCCCAGGAGCACTCCCAACTCCAATCCCCATCTGAATgccagtctcagtctcagtctcaatCTGAAGCGATCCATCGACGATGTGGCCGCCGACGATGACAGCCTGCTGGAGgacgatgaggatgaggaggatgagggggagggcgagggcgaggaggagctgctgctggacgaGGCTGAGGAGGATCGGATGGTAGAGCAAATGGAGGCGCAGCAAATCCTGTTGGTCACAGCCGCCGCAGAGGACAGCCACCATCTGCTGATCAAGGACGAGTATCCCGAGGAGGAGTACGAGATGATTGAGAAAGATATTGAATTGTATTGA
Protein Sequence: MASIKSEMPPLHAAEALASSSATDSGGGGGGGGGGGTAAGSGGSGGAGTGAAGGGVNSAPATPNATISAAADSSDNQPGTPQPPQQQQPPQQQQQQPQQQQQQTQQQQQQSMATDPQVTGITHQPYATHHMYSASGQPQQQQQQQQQQQQQQQQLYGGLYGGEMQQQSYASSYINSYEQFYQQQQQQQQQSSDYSFGGGLGGGGDYSKHAAQSSGVRYHPYLQTPTSALPSAAEEAVSAPSAVSTTTSAMSPRVVSSSSPTSTSSHLQLGGPPGSPSGAGGGGGGCKLQCKKCGILTTNEQELQEHIANVHGESPYGSSGYASSPYIKEEMPTPQPPGGSNPGELLDLDSQKMVYHQQLLQQQQQQQQHQHEAVVGGLPLSLPDPLHSMQSMQQRALHSWEQPQAGVGVGVEGLPPYMQQQPGLSLGLGVGLGVGVDKSPYYSPKQSPYHQAGGGGVGVGVGVGVGATLIKQEYGGHGLIKSEYPDSQHYVDKSFDPTAGSGGGVDLCANVATSPAEFPSTTTGGPGQDGAPPAVAVGQQAAYRGFEPPSSSSVLPANSLTAKAATWKSNEARRPKTYNCTACNKWFTSSGHLKRHYNTTLHKNAVKSSGQPDPATLPISAHHHPSRDPVTKPSRRGNAAAAAAAAAAAAAAASAGPQVQPPPPANVQPPEPPRSPPDYGGGGGVGAVGGAAMSQYSASPSPTTQQQHHQHQLQQQQQQQANGNGYPGNGAANGYGYGMQQQVQSTTNASPQHASSHQQQHPHSHSQQQQQHLQQQQQQQHSSSNNNNSVLNGHPNGLAGPSAPLNTNNNNITQMPSSQMRGLLNETTTTTTPKTTPTTTPTATEAMAAIKIEHLEDSNHTHNSHNSHNSRSSSSSSSSLMAMEEEQQQQEQERAADHPQQQQLDQQEQQHQVSYLLASASHRPYSSNSNSSSNTPNTGVSSSSNTANTAVSSNSSRLSPLTIYHLQQQPPLRQEQQQLQAMDFSRTTPPPQPLPPMGMGQPQQSLLPPMGMDYNMLALDMPMPMHMPMPSSMLQCSSTSTTPLATITTTSMDTMQQQPQQLVHHYQALLHPHHQHQQQQQQQLEEEERQQQQEEHHHQHLQQQQHQQQQDPGALILAQDNMPHSSSSPGISSSPPPQQQQQQPMHTHTHTTLTMPMPMPPTMHMPITTTAQQLLPLQLQPPPPHITSTMPMPHTMHMPIMPPPPPCYQQLQPLDPTTSYHTIIGSSGAEAGYTTNGHPHQITTSDGQVLQLMPASLFAPYAPLSPYSTVAAQRSPQEGDLPPVHTLTTALQAHAQAQQEQAHTPTLTVLSTPYSPTVSSSRATPALELDMATLLQQQQQQQQQDYELEQYQHQIQQHQIDQLQQHHHHQQQMEQQALEQQHQQQQQQQQQIQLVQVDQQQQPTQTVVQSGAKKRRATAAATPSTTKRRRNSSVGSTSPHSTTLPSGRIKCLECDKEFTKNCYLTQHNKSFHSGEYPFRCQKCGKRFQSEDVYTTHLGRHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETHNRPRVVGKKSAAAAAAATAAAAAAVVAAAAAATAEAAAAASQSQQQQLVTTVVSTLPVSASATPINPIKAAFARSLTMTAVSALSPRSTPNSNPHLNASLSLSLNLKRSIDDVAADDDSLLEDDEDEEDEGEGEGEEELLLDEAEEDRMVEQMEAQQILLVTAAAEDSHHLLIKDEYPEEEYEMIEKDIELY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471941;
90% Identity: iTF_00564237;
80% Identity: -