Basic Information

Insect: Drosophila obscura
Gene Symbol: PRDM5
Assembly: GCA_018151105.1
Location: NW:1919565-1923709[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00085 0.052 13.7 0.0 2 23 210 232 210 232 0.96

2 7 1.5e-06 8.9e-05 22.4 2.8 1 23 906 928 906 928 0.98

3 7 0.00044 0.027 14.6 2.0 1 21 958 978 958 979 0.94

4 7 6.1e-05 0.0038 17.3 2.7 2 23 986 1007 986 1007 0.98

5 7 0.0089 0.54 10.5 1.1 1 23 1013 1035 1013 1035 0.98

6 7 0.0085 0.52 10.6 1.0 1 23 1041 1064 1041 1064 0.97

7 7 0.0012 0.076 13.2 0.4 1 23 1074 1096 1074 1096 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00085	0.052	13.7	0.0	2	23	210	232	210	232	0.96
2	7	1.5e-06	8.9e-05	22.4	2.8	1	23	906	928	906	928	0.98
3	7	0.00044	0.027	14.6	2.0	1	21	958	978	958	979	0.94
4	7	6.1e-05	0.0038	17.3	2.7	2	23	986	1007	986	1007	0.98
5	7	0.0089	0.54	10.5	1.1	1	23	1013	1035	1013	1035	0.98
6	7	0.0085	0.52	10.6	1.0	1	23	1041	1064	1041	1064	0.97
7	7	0.0012	0.076	13.2	0.4	1	23	1074	1096	1074	1096	0.98

Sequence Information

Coding Sequence: ATGAACGATGCGGCTTTCTCGGGCTTCTACggcggcattggcattggcaacCAGCTGCACCCGCCCctccatcagcagcagcagcaacaccaacagcaccCGCATCAGGAGCTGTCCCTGTCCACGCCCGTGCACGCCCTGGAGCCGGACACCAACTTCACGAGCTTCTTTGACGACGACATCGTGACCTGCGGCTCCACATCCTCCTCCGCCGTCTGGCTGCCCATCCAGCTGGGCAACGGCATCCTACCTAATGGAGCAGCTATCAATGCAGCGAACAAGGCAGCCGCAGAGGTTCCCTTTGTCCAGATCCACACCACggacctgcagcagcaggcgcagccCGAGAAGAGCTATCGCAATGCCTTCCGCCGCAGGACGGCGGAGATCAAGTCCGAGGAGCTGATCAAATCCGAGCTGGCCGAGGCCGCGGCCAAGGAACGCCTgaatgccacgcccacaccgcCCACGCGCAACTCCAGCTGTGCCAGCGTCGAGGGCAAGGCCATGGTGCAGGAGGTGCCGATACTCTTCAGGTGCCCCAACTGCCCGTTCCTCAGCCTCTGCGAGGTGAAGTCCAGCCAGCACGTGAACAACTGCTTCGGAACCAGCGCCGAGCAGCAGAGACAGTGTCCAGGCTGCCCGAACATCTTCTACAGCAGCGATGCCCTCAATGTGCATCTCAGCATGGACCACCAACTGGATGACGATGAGATTGCGACCCTGCTGGGCGGCACAGCCACACCGGCCGCTGCGGCCGCCTCCGGCCACAAGCAGCCGCTGCCCAAGAGCCGGATCTTCATCAAGAGCGTGGACTGCCTGAGGGAGCCCCAGCAGGATTTCCTACCACTGCTACAGCAGGACACCGACTCTCCAGTCACATCCAGCAACATTCTTGATCTGCTCGATGAGGTGGTGCAGACACCTGGTCCGCTGCCGCCCGGTGggcaagtggcagtggcgccGCCGCCCTGCCACAAGCCCAGCAGCCAGAAGATATCCATCAAGAGCGTGGACGTGCTGAGGGAGCCTGCGCTGCTGACCTTTGACTTTCAGCTGCCCAATGGCTGCCAGGAGATGCCTCTGCTGGCGGAAAGCAATCTCGTGgatgtgccagtgccagtgccagtgtcgGTGATGGAGGTGGAGCCCAAGCCGCGTCAGCCCAAGATCTACATCAGAAACGTGGACATCCTCAAGGAGCCGATGCTGCTGCCCTCGTCCCTGCCCGGCATGGGCTTCAATGGGAGCGTGGCCACGACGATAGCGATgcagaatggaggaggagttGCCAGCGATGTCTTCCAGGCGGATACGTTACTCACGCCAACGGGTCCGCTGCCAGGTTTCGAGCCCAGCCTGGCGCCCCTGGCCAACATGTGCTCCGAACCCTTTCCCTTCGACTCCGTGCTGAGTGTGGGCGGTGGTGGGGGTGCCTCCACACTGGAGAACACTCGCTTCAGTgccttggacttggactttgGCGTAGATTTTGACCATGGCATGGCGCCACTGCTCACCGAGGCCACccctccgccaccgccaccgccacagccacagcctcagccGTCAGTGCAGTCCGGCCTCTCGGAACTGGAGCAGCCCGTCCAGCTGCAGCACTACCTGCCGCCGACTCCGAGCACCACCAAGCAGAAGATCTTCATCAAGAACGTGGACATCCTGAAGGCACCGCAGCGCGGCACTCTCCACCTGCGCACCGTCGACGAGCTCAATTTTATGACCCGCAACGAGGTGGAGCGCCTTATAGTTCCCAACCTCGAACCCATGCCCAAAATGGAGCCCCTGATggaccagcagcaccagcatcagcagcagcatacgCACACGCAGCCACAGTCGCAGCCTCAGCCGCTGGATCCCCTGCAGCTGGAACCGCCCAACTCTCAGACGCTGAGCGAGTTCCAAGCTCCGCTGAGCGGCAGCTGGCCGAGCGAAGACAGCTACGACCTGGCCGGGGATCTGGAGGGCTGGCCCTGGATCGAGGAGGCAGTGCAAGAGGTCATACCAACTGAGACGGCCGCCGCCTCCGAACCACAAGTGGAGGCGCTTCCCCAGTGCTCCTCCTCTGACGATTTCCCCCAGTTGTATCCCTCGCCGCCTGAGCCAGTACAGAGCGGAGGAGACGCTGTGCCTCCCCTGGTGCCCGTCAGCGCCACGGATGATACTGCAGTCGCTGCCGCTGGCACCGCTGGACCGATCAGTCTGCCCCTTCCTCCGCTGGTTCCTCTGGCGGCGGAGGCGGGCGAGAAGCCGGGACGCATCTATGTGGCCAACAATCTGCTGCCCGCCGCCGTGGACCCGCTGCCGGGTGGAACTTCGGTGCGCGGGCGTCCCTATGGCACCAAACTATCGGCGGCGACCGGCGGAGGAAAGCGGAAAGCTGCGCCGAGCATCAGCCAGGTGGCCGAGGGAGGCAAGTGCCAGGTGGAGGGCTGCATGTTCCGCTTTAAGTCGCCGGCGACGCTGGAGTATCATGGCCGCTGCCACAACGACGTACTGGGATCGCCCCAGCCGATGGTCTGTCCAGAGTGTCGCTCCTCGGACTTCAGCAACTGGAACTGCCTGCACACGCACCTGTGGCGCACGCACCAGATCGACATGGAGCTCTACTGCTGCCAGTTGTGCAGCTTCAAGACGCCCATCTACTCGCGGCTGGTCAACACCCACGCCAAGATCCACTCCGAGGAGCGCAACTACAAGTGCGAGCAGTGCGGCAAGGGATTCAAGAACACAAAGCAGCTGAAGAACCACCGACGGCTGCACCGCACCCAGGGACTGGGCATGGGCAAAGGACCGCTCCAAGATCAGGCCACAGCCGATGCTCCTCCCGGCCCGCCCACGGCCATCCTGCATCGctgcggcgactgtggggcgGCCTTCAAGCAGCGCAAGACCCTGCGCGAGCATCTCTGCAAGGAGCGTAACGAACAGCCGCAGTGCTCCCTATGCCAGCGGCTCTTCAGCTCCAAGAGCAGCCTCAAGCTGCACCAGCGCAGCCACCAGGCGAACAAGCGCTTCCAGTGCGACACCTGCGAGTACGAGGCGAGCGACCACAACGCCTTCCGACGACATCTGGCCACGCATCGGGATCGCAAGCGATATGCGTGTCCCCATTGCGACTTTCGGGCGATACAGAGCACCGCCTTTCGGATACACCTGCAGAAGCGCCATCCCGAGCAGGAGCTCTCGTCCATCATCTACAAGTGCGATCTGTGCAGCTTCTCCAGCATCAATCAgagcctgctgctggttcACCAGGCCAAGCACGAGCACGAGGCGCCGCCACCCAACCAACAGCCGCCGcttgctgtgcctgttcccgAGGCAGCACCAGCGACGGCCTCAACTCCATCACAGATCAAGGTGGAGACCAGCCTGCTGCTCGCTCATTCCAGTACAAATGTCGCCACGAGGCAGGCGGGCGGTTCCTTGGCAGATGTCCCACAATCATTGTAA
Protein Sequence: MNDAAFSGFYGGIGIGNQLHPPLHQQQQQHQQHPHQELSLSTPVHALEPDTNFTSFFDDDIVTCGSTSSSAVWLPIQLGNGILPNGAAINAANKAAAEVPFVQIHTTDLQQQAQPEKSYRNAFRRRTAEIKSEELIKSELAEAAAKERLNATPTPPTRNSSCASVEGKAMVQEVPILFRCPNCPFLSLCEVKSSQHVNNCFGTSAEQQRQCPGCPNIFYSSDALNVHLSMDHQLDDDEIATLLGGTATPAAAAASGHKQPLPKSRIFIKSVDCLREPQQDFLPLLQQDTDSPVTSSNILDLLDEVVQTPGPLPPGGQVAVAPPPCHKPSSQKISIKSVDVLREPALLTFDFQLPNGCQEMPLLAESNLVDVPVPVPVSVMEVEPKPRQPKIYIRNVDILKEPMLLPSSLPGMGFNGSVATTIAMQNGGGVASDVFQADTLLTPTGPLPGFEPSLAPLANMCSEPFPFDSVLSVGGGGGASTLENTRFSALDLDFGVDFDHGMAPLLTEATPPPPPPPQPQPQPSVQSGLSELEQPVQLQHYLPPTPSTTKQKIFIKNVDILKAPQRGTLHLRTVDELNFMTRNEVERLIVPNLEPMPKMEPLMDQQHQHQQQHTHTQPQSQPQPLDPLQLEPPNSQTLSEFQAPLSGSWPSEDSYDLAGDLEGWPWIEEAVQEVIPTETAAASEPQVEALPQCSSSDDFPQLYPSPPEPVQSGGDAVPPLVPVSATDDTAVAAAGTAGPISLPLPPLVPLAAEAGEKPGRIYVANNLLPAAVDPLPGGTSVRGRPYGTKLSAATGGGKRKAAPSISQVAEGGKCQVEGCMFRFKSPATLEYHGRCHNDVLGSPQPMVCPECRSSDFSNWNCLHTHLWRTHQIDMELYCCQLCSFKTPIYSRLVNTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMGKGPLQDQATADAPPGPPTAILHRCGDCGAAFKQRKTLREHLCKERNEQPQCSLCQRLFSSKSSLKLHQRSHQANKRFQCDTCEYEASDHNAFRRHLATHRDRKRYACPHCDFRAIQSTAFRIHLQKRHPEQELSSIIYKCDLCSFSSINQSLLLVHQAKHEHEAPPPNQQPPLAVPVPEAAPATASTPSQIKVETSLLLAHSSTNVATRQAGGSLADVPQSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00515212;
90% Identity: iTF_00474794;
80% Identity: -