Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:3201759-3205279[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 4.5e-05 0.0027 17.7 4.8 1 23 174 197 174 197 0.97

2 16 0.00051 0.031 14.4 1.0 1 23 243 266 243 266 0.95

3 16 0.01 0.63 10.3 5.8 1 23 333 356 333 356 0.96

4 16 0.0013 0.08 13.1 0.7 2 23 412 433 411 433 0.97

5 16 6.3 3.8e+02 1.6 1.1 1 20 546 565 546 567 0.88

6 16 0.013 0.81 10.0 0.5 1 23 576 598 576 598 0.94

7 16 0.0001 0.0062 16.6 0.9 1 23 605 628 605 628 0.97

8 16 0.0007 0.043 14.0 0.8 2 23 637 658 636 658 0.95

9 16 0.0033 0.2 11.9 0.1 2 20 685 703 684 708 0.90

10 16 0.0015 0.094 12.9 1.6 1 23 743 766 743 766 0.96

11 16 3 1.8e+02 2.6 0.7 3 22 775 794 773 794 0.95

12 16 0.3 18 5.7 1.9 1 23 803 826 803 826 0.95

13 16 3.6e-05 0.0022 18.0 0.1 1 23 848 871 848 871 0.97

14 16 0.034 2.1 8.7 0.2 1 23 881 903 881 903 0.94

15 16 5.9e-05 0.0036 17.4 3.7 1 23 909 931 909 931 0.99

16 16 6e-06 0.00037 20.5 3.2 1 23 937 959 937 959 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	4.5e-05	0.0027	17.7	4.8	1	23	174	197	174	197	0.97
2	16	0.00051	0.031	14.4	1.0	1	23	243	266	243	266	0.95
3	16	0.01	0.63	10.3	5.8	1	23	333	356	333	356	0.96
4	16	0.0013	0.08	13.1	0.7	2	23	412	433	411	433	0.97
5	16	6.3	3.8e+02	1.6	1.1	1	20	546	565	546	567	0.88
6	16	0.013	0.81	10.0	0.5	1	23	576	598	576	598	0.94
7	16	0.0001	0.0062	16.6	0.9	1	23	605	628	605	628	0.97
8	16	0.0007	0.043	14.0	0.8	2	23	637	658	636	658	0.95
9	16	0.0033	0.2	11.9	0.1	2	20	685	703	684	708	0.90
10	16	0.0015	0.094	12.9	1.6	1	23	743	766	743	766	0.96
11	16	3	1.8e+02	2.6	0.7	3	22	775	794	773	794	0.95
12	16	0.3	18	5.7	1.9	1	23	803	826	803	826	0.95
13	16	3.6e-05	0.0022	18.0	0.1	1	23	848	871	848	871	0.97
14	16	0.034	2.1	8.7	0.2	1	23	881	903	881	903	0.94
15	16	5.9e-05	0.0036	17.4	3.7	1	23	909	931	909	931	0.99
16	16	6e-06	0.00037	20.5	3.2	1	23	937	959	937	959	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGCGATACAAATGGGCGTTACTGGATTGAGACGCCGGTGGATAAGTATGCCGAGAAGACCTTCAATCAGCTGTTGCTGGAGCTAACCAAGATTGAGTTGACCATGGTCCAGGCCGAGAAGTTGCCCCACTGGCTGTGCTCCAGCTGCTCCCAGAAGCTGGAGAGCGCCTATGACTTTGTGCTGCAGGCGAAACAGATGCACAAGCTGTGGCTGCAACAACTGGAAGATACGGGGCAGATAATGAGCACTGGAGCGTTGGAGTGCCTGCGGGAGACACCCATACATCTGTTTGAGATCGAGGGTGTTACCATCAAAACCGAAGCGCTGGAGTCAACGGTTGCAGACAATGGGAATAGCTCATCCGATCCTCTAGTCCGCACACGCGTCAAAAAACGGACCATTTTTCACTTTAGCGACACCGAGGATGACCAGGATGATGTGCCGCTAAGGCAGCGCAGGACGGGCAGTCAAGTGAACAGCTCATCAGCTAAGCTGCACAAGTGCAACCTGTGCGGCAAATCCTTTAGATATATTACAAATCTCTATCGCCACAAGAAAAGGGATCACGGCTATCCAGGCCCTTCAAAGGGAGAGAGCTCCGAATCCTGCCAGgacaacacacaaaagagCGCCGTGGCAGCGCAGGACAGTTCCAATTTGGAacaaaatgatgatgataatgatgggGATGATGATAACTACTACAAATGCGATCAGTGCGACAAATCCTTCAAGTACATAATGGTGCTAGTCAGGCACAAGCAGAATGCCCATGAAGCCAATCAATATCAAATGCCAATCAGATCTGGTCCCAAGCGAAGAAACAGAAGGGACGTGGGTGAAGCAGCAAGTCCAGCTTCTTCGGGGACATCCACACAACGAACCAGAATCAGCAACGACAGCCTTGTCCATAGCCTCATCAAAACAGTGCAGTTTTCGGATGAGGATGGAAACAACGGCCCCGATAACTACTACAAGTGTGATCAGTGCCACAGATCGTACAAATACATTGTAAGCCTCAtcaagcacaagcacaaggaTCACACGGAAGCTGACAAAAACTCGGACGCCGAGGACAATCAACCATTAGCCTCCACATCCGCCTGCGCCTCCGCAGCCTCAGGCACTGCCACCAAGGCATCGCGAATCAATCGTCGCGTTCAGGGCTTTGACCTGCATCGCTGCGAGCCAAATGGTGCAAAGGAAATTCAGTGCATGATCTGTCTGCGGAAATTCACTAAGCTGCGGGAGCTGAGAGATCACCTGAGGGCGCATCCCACAGACTTTAATTTCCAGGCGCACGGCGAGCCCATCGAACGCATTGCCGAGGGCTTCTTCAAGACGGCTGTGGAGTCCACAGTGGAGGGTTTGAAGAAGAGAATTCTGCATGACCTCAAGATAGGCGTCTTCGGACGCTTCTATTCCATTACCAACGAGGCGCGCTACGAGATGAGTTTGGACAGCTCGGACACGGATAGCGATGGCGATGCAGATGTTGTACTGCGACGTAGCTATGCCTGCGAGCTATGCGACTCGCCGGAGGCCAGGTGGCCCCGCAAGTATCAGCTGCACGAGCATcacaggcagcagcacacCTGGGAAGAGGCTCCGCATGTCTGCCAGCGCTGTGATTCGCGTTTCCTAAGTCTCCAGCTGCTGGAGCATCACACCCTTCAGCTCTGCCAGAACACACTGAAGCGATACATGTGCGACAAGTGCCCGCAGCGATTCTTCTGGCGAAGAAATCTGCGTGCCCATTTGGTCGAGCACAAGAGCAAGCAAGACAACTATCCGTGCGACCAGTGCCAGCGTAGTTTTCAGGATAAAAGCGCCGTGACCAAGCACAAGTTGACGATGCATCGCGATGAAAAGAATCAGCTTATTCCCTGCCGCTGGTGCTCACGGACCTTCTATCGTCCCGCCCTCCTGCACAAGCATGTCGAACGGCATGGCTTCACCGGCGACGATTTGCCACTGGCAGAAACATTGCTGGCCGATGCAGCCAAGCCATCGGGCCCAAAGACTGTCCAGTGTAAGATCTGTGACCTGCAGTTCGTAAGCGTAGCAGATCTTCGTCGCCACAATGCAATGCTGGGCCACAGTGAGCGAATAACCGACTACATGATCAGCACCGAGGCTGGtttcgagctgctgctggaggataCAGATGACAGCGATGACGACACTACGGGCGGTAGGTCCTACTCGTGCGATCTCTGTCAGATGACGTTTCGTCGCCGGAGGGAGATGAGCGAGCATCAGTATTCACTGCACGCTTTTGACAAGCTGCCGTATGGCTGCGAACATTGCATTTATAAGACCGTGGATAAGCTCATGCTGGAGCATCATCTGCGCACACAATGTCTGAACAGCGAGAAGCCATTCAGCTGCTCCCGCTGCAGATACAAGTTCATGTGGAAGGAGAACCTGGAGCAGCACTTTGCCACTCAGCATCCCAAGCAGCTGCCCGCCCAAGAGCAGTCGTCTATGCCCCTGAGAAGAAGACGACGCTTCAGATACCAATGCCCACAGTGCTGGCGTTCGTTTGTGGTGCAGCCCAGCCTCGATAAGCATATAAGGGACATGCATGTGGCCAAGAGGAATCCGGGCAAGAAATACCTCTGCTCCCTGTGCGGCCTGGAGTCGCTGACGCCCAACAAGCTGAACATACATATGCGCCGCCACAACGGAGAAAAGCCCTTTAAATGCGATCTGTGCGACATGCGCTTCACCGTCCACTACGAGCTGAAGGTCCATCGGAGGAAGCACACCGGCGAGCGGCCCTACCAGTGCACCTTTTGTGACAAGCATTTCGCCCGACCCGACAAACTGAGACGCCATGTCTACATGCACAGTGCTCGTCGTTAG
Protein Sequence: MTRTCRICGDTNGRYWIETPVDKYAEKTFNQLLLELTKIELTMVQAEKLPHWLCSSCSQKLESAYDFVLQAKQMHKLWLQQLEDTGQIMSTGALECLRETPIHLFEIEGVTIKTEALESTVADNGNSSSDPLVRTRVKKRTIFHFSDTEDDQDDVPLRQRRTGSQVNSSSAKLHKCNLCGKSFRYITNLYRHKKRDHGYPGPSKGESSESCQDNTQKSAVAAQDSSNLEQNDDDNDGDDDNYYKCDQCDKSFKYIMVLVRHKQNAHEANQYQMPIRSGPKRRNRRDVGEAASPASSGTSTQRTRISNDSLVHSLIKTVQFSDEDGNNGPDNYYKCDQCHRSYKYIVSLIKHKHKDHTEADKNSDAEDNQPLASTSACASAASGTATKASRINRRVQGFDLHRCEPNGAKEIQCMICLRKFTKLRELRDHLRAHPTDFNFQAHGEPIERIAEGFFKTAVESTVEGLKKRILHDLKIGVFGRFYSITNEARYEMSLDSSDTDSDGDADVVLRRSYACELCDSPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDSRFLSLQLLEHHTLQLCQNTLKRYMCDKCPQRFFWRRNLRAHLVEHKSKQDNYPCDQCQRSFQDKSAVTKHKLTMHRDEKNQLIPCRWCSRTFYRPALLHKHVERHGFTGDDLPLAETLLADAAKPSGPKTVQCKICDLQFVSVADLRRHNAMLGHSERITDYMISTEAGFELLLEDTDDSDDDTTGGRSYSCDLCQMTFRRRREMSEHQYSLHAFDKLPYGCEHCIYKTVDKLMLEHHLRTQCLNSEKPFSCSRCRYKFMWKENLEQHFATQHPKQLPAQEQSSMPLRRRRRFRYQCPQCWRSFVVQPSLDKHIRDMHVAKRNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSARR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00481028;
80% Identity: -